جست‌وجوی استاد و پژوهشگر

• Radiation Oncology
• Particle Therapy
• Medical Physics
• +۴ مورد دیگر

Professor J. Debus is a distinguished academic in Radiation Oncology at Heidelberg University's Medical Faculty, with extensive research focused on particle therapy, medical physics, and cancer treatment optimization. His work spans clinical trials, radiobiology, and technical innovations in radiation delivery systems. Primary Affiliation: German Cancer Research Center (DKFZ), Heidelberg Research Focus: Particle therapy, radiation oncology, medical physics Key Collaborations: Mein S., Liew H., Tessonnier T., and other leading researchers in radiation oncology Professor Debus' research interests center on advancing particle therapy techniques including proton, carbon ion, and emerging modalities like helium and oxygen ion therapy. His work addresses critical challenges in radiation oncology such as normal tissue sparing, hypoxia-induced radioresistance, and precision treatment delivery. He has made significant contributions to understanding the biological effects of different radiation types and optimizing treatment protocols for various cancer types including head and neck cancers, brain metastases, and prostate cancer. His recent publications demonstrate leadership in clinical trials (GUARD, ESTRON, PROBASE) and technical innovations in radiation delivery systems, particularly in the emerging field of FLASH radiotherapy and ultra-high dose rate treatments. Professor Debus has published extensively on treatment planning optimization, radiation-induced biological effects, and imaging techniques for precise radiation delivery. Leading clinical trials in particle therapy Developing novel techniques for normal tissue protection Advancing understanding of radiation biology across different modalities Professor Debus has secured significant research funding for his work in radiation oncology and particle therapy. His research has contributed to clinical implementation of advanced treatment techniques at the Heidelberg Ion-Beam Therapy Center (HIT), one of the world's leading facilities for particle therapy. He supervises numerous doctoral students and postdoctoral researchers in the radiation oncology field. His laboratory and research team focus on translational research bridging basic radiobiology with clinical applications, with particular emphasis on optimizing treatment protocols for challenging tumor types and improving patient outcomes through precision radiation therapy.

Sebastiaan Breedveldمشاهده پروفایل

دانشیار

• Radiation Therapy
• Applied Mathematics
• Decision-Making
• +۳ مورد دیگر

Dr. Sebastiaan Breedveld is an Associate Professor in the Department of Radiation Oncology at Erasmus University Medical Center in Rotterdam, The Netherlands. His research focuses on improving radiation therapy through applied mathematics, multi-criteria optimization, and automated treatment planning. He developed the clinically implemented Erasmus-iCycle algorithm and leads projects like TROTS (Radiotherapy Optimisation Test Set). Education includes a PhD in Medical Physics (cum laude) from Erasmus University Rotterdam and an MSc in Applied Mathematics from Delft University of Technology. Research interests center on developing computational methods for real-time, personalized radiotherapy. Key areas include: Large-scale optimization for treatment planning Deep learning for instantaneous dose prediction Multi-criteria decision analysis for balancing treatment trade-offs Proton therapy and VMAT techniques High-performance computing applications Recent publications demonstrate strong focus on AI-driven automation in brachytherapy, IMPT robustness, and FLASH proton therapy. Work consistently addresses clinical translation of mathematical optimization. Significant scientific awards include: NWO Vidi Grant (2021) for INSTORAD project NWO Veni Grant (2016) MCDM Doctoral Dissertation Award (2015) Erasmus MC Efficiency Grant (2015) PhD with honors (2013) Leads research group supervising 2 post-docs, 11 PhD students, and numerous master/bachelor projects. Major grants support work in proton therapy optimization and automated planning systems. Developed TROTS dataset for benchmarking radiotherapy optimization algorithms and collaborates internationally through projects like BiCycle for automated brachytherapy planning.

Stephanie E. Combsمشاهده پروفایل

استاد

• Radiation Oncology
• Radiation Therapy
• Highly Conformal Radiation Therapy
• +۸ مورد دیگر

Prof. Dr. Stephanie E. Combs is a leading academic in Radiation Oncology at Technische Universität München (TUM), holding the position of Professor and Chair of the Department of Radiation Oncology. She also serves as the Dean of the TUM Faculty of Medicine since 2022. Her expertise spans highly conformal radiation therapy techniques (e.g., IMRT/IGRT/ART, proton, and carbon ion therapy), with a focus on brain and skull base tumors, pediatric oncology, gastrointestinal oncology, and biomarker-driven therapies. Prof. Combs studied medicine in Heidelberg and the United States, completed postdoctoral training in Heidelberg, and became Vice Chair of Radiation Oncology there before joining TUM in 2014. She has held leadership roles, including heading the TUM Senate from 2019 to 2022. Her research emphasizes precision medicine, radiation biology, and translational radiotherapy innovations. Her awards include the Basic/Translational Senior Science Award (2019), Robert Janker Award (2012), and multiple honors from German and international radiation oncology societies. Her work bridges clinical practice and research, with contributions to guidelines on target delineation for glioblastoma and skull base tumors. Prof. Combs’ publications focus on advancing radiation techniques, radiomics, and personalized therapy, with over 300 peer-reviewed articles. She leads initiatives in education, including a Master of Science program in Radiation Biology, and collaborates internationally in translational research.

• Radiation Oncology
• Head and Neck Cancer
• Carbon Ion Therapy
• +۵ مورد دیگر

Dr. T. Held is an active researcher and faculty member in the Department of Radiation Oncology at Heidelberg University's Faculty of Medicine. With numerous publications spanning 2022-2025, Dr. Held has established expertise in advanced radiotherapy techniques, particularly focusing on head and neck cancer treatment. Dr. Held's research interests center on radiation oncology with specialization in head and neck cancer, carbon ion therapy, particle radiotherapy, and radiotherapy dosimetry . Their work investigates innovative approaches to minimize complications while maximizing treatment efficacy, with a particular focus on tissue retraction devices, re-irradiation techniques, and oral complications following radiotherapy. Analysis of recent publications reveals a strong emphasis on clinical trials and translational research in radiation oncology, with significant contributions to understanding optimal treatment approaches for head and neck cancers, meningiomas, and other complex malignancies. The research demonstrates expertise in both photon and particle-based radiotherapy modalities. Dr. Held actively collaborates with researchers across the Heidelberg University Hospital and German Cancer Research Center, contributing to multidisciplinary approaches to cancer treatment. Their work appears in high-impact journals including Radiation Oncology , Head & Neck , and Cancers .

• Radiation Oncology
• Cancer Therapy
• Radiotherapy Techniques
• +۳ مورد دیگر

L. Bauer is a Physician Scientist in the Department of Radiation Oncology at Heidelberg University Hospital, affiliated with Heidelberg University's Faculty of Medicine. Their research focuses on advanced radiotherapy techniques and cancer biology, with particular expertise in radiation oncology applications for complex cancer cases. Bauer's research interests span radiation oncology, cancer therapy development, and molecular oncology. Their work demonstrates significant contributions to understanding both technical aspects of radiotherapy delivery and biological mechanisms of cancer progression. They have particular expertise in carbon ion therapy applications and the role of tumor microenvironment in cancer metastasis. Analysis of Bauer's recent publications reveals a dual focus: developing advanced radiotherapy techniques for rare cancers like mucosal melanomas, and investigating molecular mechanisms of cancer progression, particularly neural invasion in pancreatic cancer. Their work bridges clinical radiation oncology with fundamental cancer biology research. Bauer appears to be actively collaborating with multiple research teams at Heidelberg University Hospital, particularly within the radiation oncology department. Their research likely involves both clinical trials and laboratory investigations, reflecting the physician-scientist role they occupy. Current work appears focused on optimizing radiation therapy protocols while investigating underlying biological mechanisms of treatment response.

Jan Wilkensمشاهده پروفایل

استاد

• Medical Radiation Physics
• Radiation Therapy with Photons and Particles
• Laser-driven Ion Beams
• +۳ مورد دیگر

Jan Wilkens is a Professor for Advanced Technologies in Radiation Therapy at the Department of Radiation Oncology and Radiotherapy , Technical University of Munich (TUM), since 2008. As head of the Medical Physics Unit since 2012, he focuses on innovations in Medical Radiation Physics Radiation Therapy with Photons and Particles Laser-driven Ion Beams Treatment Planning and Dose Optimization Medical Imaging . His research emphasizes advanced radiation therapy technologies, including microbeam irradiation, X-ray dark-field imaging, and spectral CT for electron density measurement. Recent publications highlight applications in Radiation-induced lung injury detection Synctrotron-based imaging Proton and ion beam therapy Dose redistribution strategies . Key trends in his work include radiation biology studies, medical imaging innovations for early damage detection, and machine learning integration (implied through departmental collaborations). His experimental models span murine lung injury and synchrotron radiation applications in clinical contexts.

Mark Bangertمشاهده پروفایل

پژوهشگر

• Radiation Therapy Physics
• Intensity-Modulated Radiation Therapy
• Beam Angle Optimization
• +۴ مورد دیگر

Mark Bangert is a researcher in the Department of Medical Physics in Radiation Oncology at the German Cancer Research Center (DKFZ) in Heidelberg, Germany. His work focuses on optimizing radiation therapy treatments through advanced computational methods and physics principles, particularly for complex cases involving critical organs at risk. Dr. Bangert completed his PhD at Heidelberg University in 2011 with a dissertation titled 'New concepts for beam angle selection in IMRT treatment planning: From heuristics to combinatorial optimization.' His doctoral work was supervised by Prof. Uwe Oelfke and Prof. Wolfgang Schlegel, established experts in medical physics and radiation oncology. His research spans radiation therapy physics, intensity-modulated radiation therapy (IMRT), beam angle optimization, proton therapy, and treatment planning. Dr. Bangert pioneered methods for selecting optimal beam angles in IMRT, demonstrating that noncoplanar beam configurations could significantly reduce radiation doses to organs at risk while maintaining target coverage. His early work established the importance of integrating fluence optimization into beam angle selection. Analysis of his publication history reveals an evolution from traditional IMRT optimization to sophisticated multi-modality treatment approaches combining photons with particle therapies (protons, carbon ions, and helium). His recent work emphasizes probabilistic modeling to address range uncertainties in particle therapy, analytical dose calculation methods, and the integration of biological optimization into treatment planning. He has made significant contributions to open-source software development for radiation therapy planning education. Dr. Bangert has played a key role in developing matRad, an open-source multi-modality treatment planning toolkit designed for educational purposes. This software provides accessible tools for students and researchers to explore radiation therapy planning concepts without commercial constraints. His work bridges theoretical optimization methods with practical clinical applications, improving treatment precision while minimizing damage to healthy tissues.

• Radiation Oncology
• Particle Therapy
• MR-guided Radiotherapy
• +۳ مورد دیگر

Regnery S. is a researcher at the Department of Radiation Oncology, Faculty of Medicine, Heidelberg University. Current research focuses on advanced radiotherapy techniques including particle therapy and MR-guided treatment approaches. Research interests center on improving radiotherapy outcomes for challenging tumor locations, particularly ultracentral lung tumors and mucosal melanomas. The work emphasizes technical innovations in radiation delivery while minimizing damage to critical structures. Recent publications demonstrate expertise in stereotactic radiotherapy, carbon ion therapy integration, and MR-guided treatment planning. The research contributes to clinical protocols for difficult-to-treat malignancies requiring precise radiation delivery. Scientific contributions include: Developing techniques for bronchial tree protection during lung tumor radiotherapy Establishing protocols for combined intensity-modulated and carbon ion therapy for mucosal melanomas Collaborates extensively with clinical teams at Heidelberg University Hospital, contributing to treatment planning and outcome analysis for complex radiotherapy cases. Research bridges physics-based treatment planning with clinical implementation in radiation oncology.

Maarten Dirkxمشاهده پروفایل

پژوهشگر

• Online adaptive radiotherapy
• Image-guided and surface-guided radiotherapy
• Automated external beam treatment planning
• +۳ مورد دیگر

M.L.P. (Maarten) Dirkx is a researcher and medical physicist at Erasmus MC's Radiation Oncology department, specializing in online adaptive radiotherapy , image-guided radiotherapy , and automated treatment planning . Since 1997, he has focused on clinical implementation of advanced radiation therapies and personalization of patient treatments. Education : Physics degree from Eindhoven University of Technology (1990) PhD : 'Static and dynamic beam intensity modulation using a multileaf collimator' from Erasmus University Rotterdam (2000) His research emphasizes innovation implementation protocols , CBCT imaging systems , and treatment planning accuracy . Recent work includes automated planning for prostate/lung cancer and AI-driven autosegmentation in pelvic imaging. Dirkx supervises medical physics residents and has led three PhD projects, alongside mentoring multiple master's and QME students. He contributes to professional advisory boards (FMS, NVRO) and leads the project 'Implementation and evaluation of automated treatment planning.'

• Operations Research
• Optimization
• Network Flows
• +۳ مورد دیگر

Prof. Horst W. Hamacher is a Professor in the Department of Optimization at the University of Kaiserslautern's Faculty of Mathematics. His research focuses on optimization, operations research, and their applications in logistics, healthcare, and disaster management. Key areas include network flow optimization, evacuation planning models, radiation therapy treatment design, and hub location problems. He leads the Optimization Group (AG Optimierung), developing algorithms for complex systems. His work integrates theoretical advancements with practical solutions, such as minimizing beam-on time in radiation therapy and optimizing urban evacuation routes. He has authored/co-authored over 100 journal papers and book chapters, including seminal contributions to facility location theory and dynamic network flows. Collaborations span academic and industrial partners, addressing challenges in public transportation, medical engineering, and sustainable urban planning. Notable projects include the 'OptionS' initiative for sustainable water management optimization and the 'FlowLoc' framework for evacuation dynamics. He actively contributes to interdisciplinary education, bridging mathematics with real-world applications like robotic assembly and infrastructure design.

Frederik Dammمشاهده پروفایل

استاد

• Hematology
• Oncology
• Tumor Immunology
• +۵ مورد دیگر

Prof. Dr. med. Frederik Damm is a Professor and Managing Senior Physician at the Department of Hematology, Oncology and Cancer Immunology at Charité – University Medicine Berlin (Campus Virchow-Klinikum). He serves as Director of the Molecular Cancer Research Center (MKFZ) and leads research initiatives in clonal hematopoiesis, leukemia genomics, and immunotherapeutic applications. Primary Affiliation: Charité – University Medicine Berlin Leadership: Director of the Molecular Cancer Research Center (MKFZ) Research Focus: Dr. Damm investigates clonal hematopoiesis, tumor heterogeneity in AML and lymphomas, and therapeutic resistance mechanisms. His work integrates genomic profiling, epigenetics, and machine learning for outcome prediction in hematologic malignancies. Article Trends: Recent publications emphasize clonal evolution in cancers, CAR T-cell therapy applications across hematologic and autoimmune diseases, and genomic aberrations in AML and lymphomas. Collaborative efforts with the HARMONY Alliance highlight big data approaches to refine treatment strategies. Technical Networks: Dr. Damm collaborates with the HARMONY Alliance and contributes to precision oncology through next-generation sequencing, CRISPR modeling, and international clinical trial datasets.

• Radiation Oncology
• Head and Neck Cancer
• Prostate Cancer
• +۷ مورد دیگر

Dr. Julie Kang is an Associate Professor of Therapeutic Radiology at Yale School of Medicine and a board-certified radiation oncologist specializing in the treatment of head and neck, prostate, bladder, and skin cancers. She is affiliated with Yale Cancer Center and practices at the Smilow Cancer Hospital Care Center at Trumbull. Dr. Kang previously worked at Memorial Sloan Kettering Cancer Center before joining Yale. Dr. Kang received her BS from Yale University (2002), followed by a PhD (2008) and MD (2010) from the University of Southern California. She completed her radiation oncology residency at UCLA (2015). Her research focuses on optimizing cancer treatment outcomes while minimizing toxicity, with particular emphasis on HPV-associated oropharyngeal cancer, laryngeal and hypopharyngeal cancers, and thyroid cancer. Dr. Kang has published over 80 papers with more than 1,030 citations, with recent work exploring radiation dose de-escalation strategies, comparative effectiveness of different radiation techniques, and applications of artificial intelligence in oncology. Dr. Kang's publication trends show a strong focus on head and neck oncology, particularly HPV-related cancers. Her research combines clinical investigation with innovative approaches like natural language processing to analyze pathology reports and AI for biomarker extraction. This multidisciplinary approach bridges traditional radiation oncology with cutting-edge computational methods. Kaiser Permanente Everyday Hero Award (2017) Kaiser Permanente Physician Merit Award (2016) Dr. Kang is actively involved in clinical trials and cooperative groups, mentoring the next generation of cancer researchers. Her work focuses on radiation therapy optimization and personalized treatment approaches. She is particularly interested in addressing cancer disparities and reducing barriers to care, ensuring equitable access to advanced cancer treatments.

• Radiation Oncology
• Thoracic Radiotherapy
• Head and Neck Cancer Treatment
• +۷ مورد دیگر

Dr. Henry S. Park is a Professor of Therapeutic Radiology at Yale School of Medicine, where he serves as Vice Chair for Clinical Research and Chief of both the Thoracic Radiotherapy Program and PET-Guided Radiotherapy Program. At the Yale Cancer Center, he is Assistant Medical Director of the Clinical Trials Office and Associate Leader of the Lung Clinical Research Team. He also serves as Head of Horstmann House in the Office of Student Affairs, overseeing one of six advisory houses for medical and physician associate students. Dr. Park received his undergraduate degree from Yale College in 2007, a Master's in Public Health from Harvard University in 2012, and his MD from Yale School of Medicine in 2012. He completed his internal medicine internship at Harvard Medical School's Beth Israel Deaconess Medical Center in 2013 before returning to Yale for his radiation oncology residency and chief residency. He joined the Yale faculty in 2017, was named associate professor and vice chair in 2022, and was promoted to Professor in 2025. His research focuses on clinical trials, real-world evidence, novel radiotherapy technology, and health services with specialization in lung and head/neck cancers. His work spans developing prognostic systems for oral cavity carcinoma, investigating optimal timing of systemic therapy in nasopharyngeal cancer, studying molecular markers in lung cancer treatment, and analyzing opioid prescribing patterns in cancer patients. Dr. Park has co-authored over 200 peer-reviewed publications and serves as an associate editor for Advances in Radiation Oncology and American Journal of Clinical Oncology. Outstanding Reviewer Award from Advances in Radiation Oncology (2023) Outstanding Reviewer Award from International Journal of Radiation Oncology (2022) Educator of the Year Award from Association of Residents in Radiation Oncology (2022) Clinician of the Year Award from Yale School of Medicine (2021) Outstanding Reviewer Award from International Journal of Radiation Oncology (2020) Dr. Park leads multiple clinical trials including the RAPTOR trial (Principal Investigator) investigating consolidation radiation + immunotherapy for extensive-stage small cell lung cancer, and the MAVERICK trial (Principal Investigator) comparing MRI brain surveillance versus prophylactic cranial irradiation in small-cell lung cancer. He also serves as Sub-Investigator on trials studying stereotactic body radiation therapy for centrally located lung cancer and oligoprogression in renal cell carcinoma. As Chief of the Thoracic Radiotherapy Program and PET-Guided Radiotherapy Program, Dr. Park oversees the application of advanced radiation techniques including stereotactic body radiation therapy, image-guided radiation therapy, and intensity-modulated radiation therapy for treating patients with lung and head/neck cancers at Smilow Cancer Hospital in New Haven.