جست‌وجوی استاد و پژوهشگر

Eleuterio F. Toroمشاهده پروفایل

استاد

• Computational Fluid Dynamics
• Numerical Methods for Partial Differential Equations
• Hyperbolic Balance Laws
• +۷ مورد دیگر

Eleuterio F. Toro is a Professor at the University of Trento, Italy, affiliated with the Department of Civil, Environmental and Mechanical Engineering within the College of Engineering. He is internationally recognized for his pioneering work in computational fluid dynamics and numerical methods for partial differential equations, particularly hyperbolic balance laws. His development of high-order schemes such as ADER, HLLC, and WAF has significantly advanced simulation capabilities in science and engineering. BSc Honours in Pure Mathematics, University of Warwick (1977) MSc in Applicable Mathematics, University of Dundee (1978) PhD in Computational Mathematics, University of Teesside (1982) Doctor Honoris Causa, Universidad de la Frontera, Chile (2012) His research focuses on high-resolution numerical methods, shock-capturing techniques, and more recently, the mathematical modeling of cranio-spinal fluid dynamics and its implications in neurodegenerative diseases such as Multiple Sclerosis, Parkinson’s, and Meniere’s disease. He promotes a holistic modeling approach integrating arterial blood, venous blood, interstitial fluid, cerebrospinal fluid, and the brain’s lymphatic system. The analysis of his recent publications reveals a strong trend toward interdisciplinary applications of numerical methods in biomedical contexts, especially neurofluid dynamics. His earlier works laid the foundation for modern computational fluid dynamics, while recent efforts bridge mathematics, engineering, and medicine. Scientific Awards: Doctor Honoris Causa, Universidad de la Frontera (2012) Officer of the Order of the British Empire (OBE) Toro has advised numerous students and postdoctoral researchers and has collaborated extensively with academics and medical professionals across Europe, the USA, and Chile. His work is supported by international conferences, workshops, and research collaborations. He has organized and taught intensive short courses, such as the Trento Winter School on Numerical Methods, and delivered plenary lectures at major conferences including ISMRM and CMBE. He leads research initiatives centered on mathematical modeling of body-fluid interactions, particularly in the central nervous system. His team develops computational frameworks to simulate neurovascular dynamics and test hypotheses linking venous anomalies to neurological diseases.

Aziz El Amraouiمشاهده پروفایل

پژوهشگر

• Sensory Neuroscience
• Hearing Disorders
• Vision Impairment
• +۱۲ مورد دیگر

Aziz El Amraoui is a leading researcher and Head of the Progressive Sensory Disorders (PSD) research unit at the Institut de l’Audition, part of the Institut Pasteur in Paris, France. His work focuses on understanding and treating progressive sensory impairments, particularly those affecting hearing, balance, and vision, with a special emphasis on Usher syndrome. His research spans molecular genetics, advanced imaging, electrophysiology, and gene therapy. He investigates disease mechanisms, environmental modulators (e.g., aging, noise), and develops innovative treatments using AAV vectors, mini-genes, and CRISPR-based technologies. His team utilizes murine and porcine models to study disease progression and therapeutic efficacy across species. Recent key discoveries include identifying CLRN2 as a novel deafness gene (DFNB117), developing effective gene therapy for progressive hearing loss with a narrow therapeutic window, and resolving the Usher vision loss paradox by identifying the role of calyceal processes in human photoreceptors—structures absent in mice. His publication record shows consistent output in high-impact journals such as Molecular Therapy, EMBO Molecular Medicine, and PNAS, with work spanning genetics, neurobiology, and translational medicine. His research has direct implications for early diagnosis, personalized treatment, and the development of scalable gene therapies for sensory disorders. Progressive Hearing Loss and CLRN2 gene therapy Usher Syndrome pathogenesis and treatment Evolution of sensory systems (e.g., spectrin βV) Noise- and age-induced hearing loss Vestibular deficits in deafness Gene editing and delivery systems He leads multiple funded projects including FFB USH1B, UsherModels, HearInNoise, and TherapUsher, and actively mentors PhD and Master’s students. His collaborative network includes institutions in the UK, Germany, and beyond. Aziz El Amraoui’s work is central to advancing precision medicine for sensory disorders, bridging fundamental science with therapeutic innovation to improve the lives of millions affected by hearing and vision loss.

Jennie Cederholmمشاهده پروفایل

دانشیار

• auditory neuroscience
• electrophysiology
• sensory neuroscience
• +۶ مورد دیگر

Jennie Cederholm is an Associate Professor and Head of Physiology at the University of New South Wales (UNSW), Faculty of Medicine & Health, School of Biomedical Sciences. She maintains her research laboratory at the Translational Neuroscience Facility, Level 3SW, Wallace Wurth, UNSW. Dr. Cederholm earned her MSc in Medical Biology from Linköping University in Sweden and completed her PhD in Biomedical Sciences from the University of South Australia, Adelaide. She further enhanced her educational credentials with a Graduate Certificate in University Learning and Teaching from UNSW Sydney. Her research program focuses on auditory neuroscience, with particular expertise in integrated cellular and systems electrophysiology. Dr. Cederholm has developed significant expertise in biophysical analysis of recombinant protein expression in neurons, evoked potential electrophysiology analysis of sensory circuits, and transcriptomic analysis of gene regulation in response to physiological stimuli. Her groundbreaking work on purinergic hearing adaptation led to a patent filing that enables prediction of vulnerability to noise-induced hearing loss, with support from both industry partners and NHMRC Ideas grants. Her research demonstrates a clear trajectory from fundamental neuroscience discoveries to clinical applications , particularly in developing diagnostic tools and therapeutic approaches for hearing disorders. Dr. Cederholm has received numerous accolades including the Mark A. Smith prize (2010), Advanced Higher Education Fellowship (2021), School of Biomedical Sciences Teacher of the Year (2022), and multiple Faculty of Medicine & Health awards in 2023. She serves as the NSW Coordinator of the Australian Brain Bee Challenge since 2017 and co-leads the Faculty of Medicine & Health Gender Equity group. As an education-focused academic, she teaches extensively across UNSW Medicine and Science programs in Physiology and Neuroscience. Dr. Cederholm has supervised 3 ILP students and 7 Honours students, and currently supervises a PhD student in auditory neuroscience. She has secured significant funding as a Chief Investigator on multiple category I grants including NHMRC and Australia's Economic Accelerator Seed grant for projects utilizing Bionic-array Directed Gene Electrotransfer (BaDGE®) technology for treating brain disorders and macular degeneration. Dr. Cederholm is actively engaged in translational research through her role as co-inventor on a patent related to hearing diagnostics and through her leadership in the Australian and New Zealand Purine Club, which she helped establish as a forum for researchers studying purinergic signaling.

Elvis Pandzicمشاهده پروفایل

مدرس ارشد

• Advanced Fluorescence Microscopy
• Image Correlation Spectroscopy
• Single-Molecule Biophysics
• +۴ مورد دیگر

Dr. Elvis Pandzic is a Senior Lecturer and Advanced Fluorescence Microscopy Specialist at the University of New South Wales (UNSW Sydney), affiliated with the School of Biomedical Engineering. He operates within the Katharina Gaus Light Microscopy Facility at UNSW's Mark Wainwright Analytical Centre. With over 15 years of programming experience in MATLAB, Dr. Pandzic applies his expertise in cellular and molecular biophysics to develop tailored image analysis approaches for biomedical research. PhD in Biological Physics (2013) from McGill University, Canada His research focuses on advanced image analysis techniques, particularly Image Correlation Spectroscopy , which quantifies sub-cellular structures and protein dynamics in live cells. He also has extensive experience in single-molecule approaches such as dSTORM, PALM, and sptPALM acquired during two years of post-doctoral work. His methodologies help quantify protein density, oligomerization, co-localization, and dynamics. Dr. Pandzic's recent publications demonstrate his specialization in analyzing molecular dynamics in cellular environments, particularly focusing on membrane protein confinement , cytoskeletal organization , and cell signaling mechanisms . His work covers topics like CFTR clustering in cystic fibrosis, aquaporin dynamics, and actomyosin-dependent spatial patterns. At the Katharina Gaus Light Microscopy Facility, he provides expert support for researchers requiring advanced fluorescence microscopy and image analysis . His current work involves adapting methodologies to address biomedical problems for both UNSW and international research communities.

Ulises Alejandro Aregueta Roblesمشاهده پروفایل

پژوهشگر ارشد

• Biomedical Engineering
• Tissue Engineering
• Conductive Polymers
• +۴ مورد دیگر

Ulises Alejandro Aregueta Robles is an early-career researcher at the Graduate School of Biomedical Engineering at UNSW. His work focuses on developing advanced biomaterials, including hydrogel-based neural interfaces and conductive coatings for neural prosthetics such as cochlear implants and deep brain stimulators. He holds a PhD in Biomedical Engineering and a Master’s in Biotechnology. His research integrates hydrogel cell carriers to engineer biological neural networks, aiming to address nerve tissue diseases, and designs smart electrode coatings to enhance neural implant performance. Current projects include 3D tissue organoids for neural interfacing testing and improving conductive hydrogel coatings for chronic implant durability. Ulises has authored over 30 publications since 2014, with recent work focusing on platinum electrode dissolution mechanisms, bioelectronic neural interfaces, and cochlear implant optimization. His work bridges material science and clinical applications, aiming to improve neural prosthetic efficacy and longevity.

• Hearing and Balance Disorders
• Neurobiology
• Neurology
• +۶ مورد دیگر

Dhasakumar Navaratnam, MD, PhD, is a Professor of Neurology at Yale School of Medicine, with clinical and research expertise in hearing and balance disorders, stroke, and auditory neuroscience. He directs Yale's clinical neuroscience module for medical students and leads the Navaratnam Lab, focusing on molecular mechanisms of auditory/vestibular physiology and regeneration. His affiliations include Yale Medicine, Stroke Center, Hearing & Balance Program, and Interdepartmental Neuroscience Program. MD: University of Colombo (1986) PhD: Oxford University (1991) Residency/Postdoc: University of Pennsylvania (2001/1997) Research interests span auditory neuroscience, stroke pathology, and regenerative medicine. Key themes include electrical resonance in hair cells via ion channel interactions, Prestin's role in cochlear amplification, Id2-mediated regeneration in auditory epithelium, and cholinergic synaptic function. His lab explores molecular scaffolding proteins and cyclic AMP pathways in cellular regeneration. Recent publications cover high-frequency prestin dynamics, clot composition in stroke etiology, single-cell transcriptomics for inner ear regeneration, and clinical imaging strategies for dizziness. Articles integrate biophysical, molecular, and clinical approaches across neuroscience and neurology disciplines. Dr. Navaratnam contributes to Yale's Stroke Center clinical trials using single-cell RNA sequencing and serves as course director for neuroscience education. His clinical practice at Yale New Haven Hospital includes Hearing & Balance Center and 24/7 stroke service.

Jasmin Turnerمشاهده پروفایل

پژوهشگر

• Genetics
• Developmental Biology
• Cardiovascular Research
• +۳ مورد دیگر

Jasmin Turner is an academic researcher at Northumbria University with expertise in genetics, developmental biology, and cardiovascular research. She holds a PhD and advanced degrees in Biomedical Science and Microbiology. Her work focuses on understanding genetic mechanisms in embryonic development, particularly arterial valve formation and congenital heart defects. She has contributed to studies on RNA extraction methods in fetal inner ear tissue and pioneered organoid engineering for cancer drug testing. Turner's research bridges molecular biology with clinical applications, aiming to advance translational medicine.

Jian-Dong Liمشاهده پروفایل

استاد

• Inflammation Regulation
• Innate Immunity
• Respiratory Infections
• +۴ مورد دیگر

Professor Jian-Dong Li serves as Director of the Institute for Biomedical Sciences and the Center for Inflammation, Immunity & Infection at Georgia State University. His leadership spans multiple research initiatives focused on inflammatory diseases and host-pathogen interactions. Dr. Li's educational background includes an M.D. from Tsingtao University School of Medicine (1983) and a Ph.D. in Biomedical Sciences from the University of California, San Francisco (1997). His research program centers on molecular mechanisms of inflammation regulation , particularly inducible negative feedback systems involving deubiquitinases like CYLD. Key areas include: Tight regulation of inflammatory responses to prevent tissue damage Host survival mechanisms during Streptococcus pneumoniae and influenza infections Molecular pathways driving mucus overproduction in respiratory diseases Therapeutic development through drug repositioning strategies His laboratory employs multidisciplinary approaches including molecular genetics, immunology, chemical biology, and transgenic animal models. Analysis of his recent publications (2017-2022) reveals a strong focus on translational applications , with significant work on vinpocetine as an anti-inflammatory agent and exploration of CYLD's role across infectious and inflammatory conditions. The research consistently bridges fundamental signaling mechanisms with therapeutic development for respiratory diseases. Dr. Li actively mentors doctoral candidates and leads collaborative research teams investigating novel therapeutic targets. His work integrates basic science with clinical applications through partnerships with pharmaceutical researchers. His laboratory infrastructure supports comprehensive studies from molecular pathways to animal models of infection and inflammation, with particular expertise in: CYLD-mediated deubiquitination pathways TLR and NF-κB signaling networks Mucin regulation in otitis media and COPD Drug repositioning for inflammatory conditions

• Vestibular System
• Inner Ear Physiology
• Hair Cell Biology
• +۵ مورد دیگر

Ruth Anne Eatock is a Professor in the Department of Neurobiology at the University of Chicago, where she leads research on mechanosensory signaling in the inner ear. Her laboratory focuses on the mouse utricle to study fundamental neurobiological questions including mechanotransduction, sensory mapping, synaptic transmission across calyceal synapses, and neural encoding of sensory information in primary afferent neurons. PhD in Biology from Caltech, Pasadena B.Sc. Honours in Neurobiology from McGill University, Montreal M.Sc. in Biology from McGill University, Montreal Auditory Physiology training at MIT & Harvard, Cambridge/Boston Dr. Eatock's research centers on vestibular physiology with specific expertise in hair cell biology, ion channel function, and neural coding in the inner ear. Her work investigates how mechanosensitive receptor cells and primary afferent neurons process information about head movements and position. She has made significant contributions to understanding voltage-gated potassium, sodium, and calcium channels in vestibular hair cells, and how these channels shape neural signaling in the vestibular system. Her research program integrates electrophysiological, molecular, and behavioral approaches to understand sensory processing in the vestibular system. Analysis of her recent publications reveals a strong focus on potassium channel subunits (particularly KV1.8/Kcna10) and their role in vestibular hair cell function, sodium channel diversity in vestibular ganglion neurons, and the structural organization of vestibular hair cells including mirror-image orientation and membrane contact sites. Her work demonstrates how specific ion channel properties enable precise neural coding of vestibular stimuli, with implications for understanding balance disorders and developing potential therapeutic approaches. Dr. Eatock served as Principal Investigator on NIH grant R01DC012347 (Synaptic Processing in the Vestibular System) from February 2012 to February 2023. Her laboratory has trained numerous students and postdoctoral fellows who have gone on to successful careers in neuroscience and related fields. She has made significant methodological contributions to the field, particularly in techniques for recording from hair cells and vestibular afferents. The Eatock Lab at the University of Chicago comprises a team of researchers investigating signaling mechanisms in the inner ear. The lab maintains strong collaborations with other laboratories studying sensory systems, both within the University of Chicago and at other institutions. Current research focuses on understanding how specific ion channel properties enable precise neural coding of vestibular stimuli, with implications for understanding balance disorders and developing potential therapeutic approaches.

Kimberley Chapelleمشاهده پروفایل

استادیار

• Evolutionary Biology
• Vertebrate Paleontology
• Comparative Anatomy
• +۵ مورد دیگر

Kimberley Chapelle is an Assistant Professor at Stony Brook University in the Department of Anatomical Sciences. She is a South African vertebrate palaeobiologist with a focus on the comparative anatomy, systematics, locomotion, ontogeny, and osteohistology of reptiles, particularly early sauropodomorph dinosaurs. Education: PhD, Evolutionary Studies Institute, University of the Witwatersrand (2019) MSc, Evolutionary Studies Institute, University of the Witwatersrand (2016) BSc Honours, Evolutionary Studies Institute, University of the Witwatersrand (2013) BSc, University of the Witwatersrand (2012) Her research employs multidisciplinary tools such as micro-computed tomography (μCT) scanning, osteohistology, multivariate statistics, and functional anatomy to investigate how dinosaurs and their relatives grew, moved, and evolved. She also uses comparative living models to interpret the fossil record, with a particular emphasis on the ontogeny, ecology-morphology relationships, diversity, and biostratigraphic distribution of early sauropodomorphs. Her fieldwork spans South Africa, Zimbabwe, Lesotho, and the USA, targeting poorly known Triassic and Jurassic fossil localities in southern Africa. Her recent publications address sauropodomorph taxonomy, locomotion, and growth strategies across the Triassic-Jurassic boundary. Her work on Massospondylus carinatus and related taxa explores interelemental osteohistology, cranial anatomy, and locomotory shifts during ontogeny. She also investigates broader topics like snake feeding ecomorphology, trionychid turtle evolution, and sedimentological frameworks for Karoo Group deposits.

Manuela Nowotnyمشاهده پروفایل

استاد

• Sensory Physiology
• Evolutionary Biology
• Acoustic Communication
• +۷ مورد دیگر

Prof. Dr. Manuela Nowotny is a Professor of Animal Physiology at the Institute for Zoology and Evolutionary Research, University of Jena, Germany. Her research focuses on understanding sensory adaptations in the animal kingdom, particularly investigating the functions and specializations of insect and mammalian auditory systems. She leads a research group that explores how sensory organs detect and process environmental signals, with implications for understanding perception and behavior regulation. Dr. Nowotny's research interests span several interconnected areas of sensory physiology and evolutionary biology. Her work examines how sensory organs become highly specialized to detect specific environmental signals while ensuring animal survival. A major focus is on convergent evolution in hearing , where she has discovered remarkable similarities between insect and mammalian auditory systems. Her group investigates insect ears , particularly in bushcrickets, revealing specialized adaptations like the auditory fovea - previously thought to exist only in mammals. She also studies mammalian hearing mechanisms and the development of tinnitus following acoustic trauma. Her interdisciplinary approach combines biomechanics, neurophysiology, and evolutionary biology to understand how sensory information is processed at the organ level. Analysis of Dr. Nowotny's recent publications reveals a consistent focus on comparative auditory physiology across species. Her work demonstrates how insects provide valuable models for studying natural diversity in mating behavior and sensory adaptation. A recurring theme is the discovery of convergent evolutionary solutions in hearing mechanisms between phylogenetically distant species. Her research on traveling waves in insect hearing organs shows surprising similarities to mammalian cochlear mechanics, challenging previous assumptions about the uniqueness of mammalian auditory processing. More recent work has expanded into neurotoxicology, examining how pesticides affect insect auditory processing, and biomedical applications through neuromorphic engineering for hearing aids. Adolf-Messer Stiftungspreis 2009 for tinnitus research Multiple Deutsche Forschungsgemeinschaft grants (NO 841/1-1, NO 841/2-1, NO 841/4-1) Funding from Jürgen Manchot Foundation Goethe University's "Nachwuchswissenschaftler/innen im Fokus" project Dr. Nowotny's research is primarily supported by the Deutsche Forschungsgemeinschaft (DFG), with multiple grants focusing on different aspects of auditory physiology. Her work on bushcricket hearing mechanisms (NO 841/1-1 and NO 841/2-1) has revealed fundamental principles of sensory adaptation, while her tinnitus research (NO 841/4-1) explores the connection between inner ear damage and phantom noise perception. She has successfully mentored numerous researchers, with several collaborators (particularly S. Schöneich, J. Scherberich, and M. Kössl) appearing consistently across publications, suggesting a productive mentoring relationship. Her lab utilizes diverse methodologies including biomechanical measurements, neurophysiological recordings, and comparative anatomical studies. Dr. Nowotny leads a research group within the Institute for Zoology and Evolutionary Research that employs interdisciplinary approaches to study auditory systems. Her team combines expertise in entomology, mammalian physiology, biomechanics, and neuroethology to investigate sensory processing across species. The lab maintains collaborations with institutions including Goethe University and appears to have strong connections with researchers studying neurophysiology and acoustic communication. Current projects include examining the effects of pesticides on insect auditory processing and developing neuromorphic engineering applications for hearing aid technology through the NeuroSensEar project.

Paulo R. Dellaniمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Medical Imaging
• Brain Genomics
• +۲ مورد دیگر

Dr. Paulo R. Dellani serves as a Postdoctoral Researcher at the Research Center Jülich, affiliated with the Institute of Neuroscience and Medicine (INM-1), where he investigates structural and functional brain organization. His work integrates advanced neuroimaging techniques, artificial intelligence, and clinical neuroscience to explore brain architecture, connectivity, and pathology. His research interests encompass: Novel brain mapping methodologies Clinical neuroanatomy and genomic imaging Big data analytics for neural systems Diffusion tensor imaging and fiber tract analysis Neurodegenerative disorder biomarkers Recent publications demonstrate a strong focus on translational neuroscience, including MRI-based diagnostics for vestibular disorders, Alzheimer's disease biomarkers, and computational approaches to white matter tractography. Common themes include validation of imaging protocols, neuropathology characterization, and clinical application of quantitative neuroimaging techniques. Dr. Dellani contributes to the Bernstein Coordination Site and participates in teaching activities at universities. His laboratory develops tools and services supporting brain research, including the Julich-Brain atlas project.

Christopher Cederrothمشاهده پروفایل

پژوهشگر

• Hearing Loss
• Tinnitus
• Molecular Neuroscience
• +۵ مورد دیگر

Christopher R. Cederroth is a Senior Researcher and Docent at the Department of Physiology and Pharmacology , Karolinska Institutet, leading the Translational Auditory Neuroscience research group. His work focuses on preventing and curing hearing loss and tinnitus through molecular mechanisms, genetics, and circadian rhythm studies. Coordinates the Tinnitus Genetic and Environmental Risks (TIGER) project Regional Director for the EU-funded TINNET network Collaborates with institutions in Spain, Italy, Norway, Germany, and the UK Research integrates sex and gender dimensions in tinnitus pathophysiology (funded by GENDER-NET Plus) and involves interdisciplinary techniques like neuroimaging, genetics, and pharmacology. Recent publications address circadian regulation, clinical guidelines, and genetic predispositions. Key collaborations: TINNET , ESIT , and Decibel Therapeutics Coordinates the Tinnitus Research Initiative (TRI) database integration Contact: christopher.cederroth@ki.se | stop@fyfa.ki.se | Decibel Therapeutics partnership

Christopher R. Cederrothمشاهده پروفایل

دانشیار

• Auditory Neuroscience
• Tinnitus
• Hearing Loss
• +۴ مورد دیگر

Christopher R. Cederroth is an Associate Professor and Senior Researcher at the Karolinska Institutet, Department of Physiology and Pharmacology. He leads the Translational Auditory Neuroscience research group, which focuses on understanding the mechanisms of hearing loss and tinnitus to develop preventive and curative strategies. His research employs a dual approach using animal models and human genetics to identify therapeutic targets. Research Interests: Molecular Mechanisms: Synaptic decoupling in the ear and homeostatic plasticity in the brain during tinnitus. Translational Auditory Neuroscience: Bridging basic research with clinical applications for hearing disorders. Genetic Epidemiology: Identifying genetic risk factors for tinnitus and hearing loss through GWAS and family studies. Neuroimaging & Electrophysiology: Characterizing neural signatures of tinnitus severity and auditory processing deficits. His recent publications (2021–2025) demonstrate a strong focus on large-scale genomic studies (e.g., GBD collaborations), innovative therapeutic approaches (e.g., cochlear gene therapy), and neurophysiological characterization of tinnitus. Trends include leveraging global health datasets, advancing gene-editing techniques for hearing restoration, and exploring cortical/subcortical biomarkers for auditory pathologies. Labs and Teams: Heads the Translational Auditory Neuroscience group at Karolinska Institutet, fostering collaborations with clinical researchers and industry partners to accelerate drug development for hearing disorders.

Xiying Guanمشاهده پروفایل

استادیار

• Audiology
• Hearing Science
• Biomechanics of the Ear
• +۳ مورد دیگر

Xiying Guan serves as an Assistant Professor in the Department of Communication Sciences and Disorders within the College of Liberal Arts and Sciences at Wayne State University. Her academic role focuses on advancing audiological science through biomechanical research of the ear and development of innovative hearing diagnostics and therapeutic devices. Dr. Guan's research program investigates the structure-function relationship of the ear under normal and pathological conditions, with emphasis on cellular-level biomechanics. She pioneers the use of fiberoptic sensors and non-invasive imaging to measure sound transmission and inner-ear motion, while developing next-generation implantable microphone technology for hearing devices with enhanced bandwidth and signal-to-noise ratio. Her work bridges basic auditory science and clinical applications to address hearing loss. Analysis of her 2016-2020 publications reveals consistent focus on bone conduction mechanisms, superior canal dehiscence syndrome, and intracochlear pressure dynamics using human temporal bone models. Her research spans auditory biomechanics, otological pathology, and biomedical engineering for implantable hearing technologies, primarily published in high-impact journals like Scientific Reports and Hearing Research. Dr. Guan maintains active collaborations with leading researchers including Dr. H. H. Nakajima and contributes to multidisciplinary teams developing fully implantable hearing solutions. Her laboratory integrates experimental biomechanics with device engineering to translate fundamental ear physiology discoveries into clinical applications for hearing restoration.