Brent Doiron is a Professor at the University of Chicago, holding appointments in the Departments of Neurobiology and Statistics, and serving on the Committee on Computational and Applied Mathematics (CCAM). His research integrates nonlinear dynamics and statistical mechanics to study neural circuit variability, focusing on mechanisms underlying neural coding and network learning through collaborations with experimentalists in sensory systems. Education: PhD in Physics (University of Ottawa, 2004) Postdoc: Center for Neural Science at New York University (2017) Previous Roles: Mathematics Professor at University of Pittsburgh (2007-2020), Co-Director of Neural Computation Program at Carnegie Mellon Neuroscience Institute Research interests center on neuronal population dynamics, recurrent circuit mechanisms, and computational neuroscience. Current work investigates correlated variability in cortical networks, inter-areal communication, and stochastic spiking models. Recent publications emphasize cortical stability/gain modulation, asynchronous/synchronous activity balance, and Bayesian inference frameworks. Key themes include sensory processing, network plasticity, and dimensionality reduction in neural coding. Scientific Awards Alfred P. Sloan Research Fellowship in Neuroscience Vannevar Bush Faculty Fellowship Chancellor’s Distinguished Research Award (University of Pittsburgh) Active grants include NIH R01 and R90/T90 awards for neuronal dynamics research and computational neuroscience training programs.
Anirban Paul is an Associate Professor in the Department of Neuroscience and Experimental Therapeutics at Pennsylvania State University, affiliated with the Penn State Neuroscience Institute. His research focuses on cellular and molecular mechanisms of GABAergic inhibitory circuits, with particular emphasis on interneuron biology and its implications in neurological disorders. Dr. Paul's research spans multiple neuroscience domains, with primary focus on GABAergic inhibitory circuits and interneuron biology. His work investigates how specific neuron subtypes, particularly Chandelier cells and cortical interneurons, contribute to brain function and dysfunction. He has made significant contributions to understanding the role of these cells in schizophrenia, Alzheimer's disease, and other neurological conditions. His research integrates molecular, cellular, and systems-level approaches to uncover fundamental mechanisms of neural circuit assembly, plasticity, and function. Key areas include RNA regulation in neuronal development, transcriptomic subtypes of inhibitory neurons, and cell-type specific vulnerabilities in neurodegenerative diseases. His research portfolio demonstrates consistent productivity with publications spanning from 2003 to 2025, showing an evolving focus from basic molecular neuroscience to translational research in neurological disorders. Recent work emphasizes single-cell analysis techniques and the role of specific interneuron populations in disease mechanisms, particularly in schizophrenia and Alzheimer's disease. His publications appear in high-impact neuroscience journals including Neuron, BMC Biology, and Frontiers in Cellular Neuroscience. Dr. Paul has received the NARSAD Young Investigator Award (2018), recognizing his promising research in neuroscience. His scientific contributions have been supported by multiple competitive grants from prestigious organizations including the National Institute on Aging (NIA) and the Brain and Behavior Research Foundation. He serves as Principal Investigator on multiple active research projects, including two major grants from the National Institute on Aging focused on cell-type specific risk and resilience in Alzheimer's disease and aging (2021-2024 and 2024-2026), as well as previous projects from the Brain and Behavior Research Foundation investigating Chandelier cells in schizophrenia. His research program demonstrates sustained funding and scientific leadership in the field of interneuron biology and its clinical implications.
Marc V Fuccillo is an Associate Professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, where he leads a research laboratory focused on understanding the neural circuit mechanisms underlying behavioral control. His work bridges molecular, synaptic, and behavioral approaches to investigate how striatal circuits regulate mouse behavior from simple motor patterns to complex goal-directed actions. Fuccillo holds dual appointments in the Neuroscience and Cell and Molecular Biology Graduate Groups at Penn and maintains an active laboratory investigating the synaptic and circuit basis of neuropsychiatric disorders. Education: B.A. in Molecular and Cellular Biology and Music Performance (Violin) from Brown University (1998) Ph.D. in Developmental Genetics from New York University School of Medicine (2007) M.D. from New York University School of Medicine (2008) Fuccillo's research centers on the synaptic and circuit mechanisms of behavioral control, with particular emphasis on striatal circuits. His laboratory employs a range of technologies including mouse genetics, in vitro electrophysiology, in vivo imaging, and quantitative behavioral analysis to explore how neural circuits of the striatum regulate behavior and how disruptions in these circuits contribute to neuropsychiatric disorders. His work has particularly focused on autism-associated abnormalities in behavioral control, examining how synaptic adhesion molecules like neuroligins and neurexins shape circuit function and behavior, with significant findings regarding D1 dopamine receptor positive medium spiny neurons in the nucleus accumbens. Analysis of Fuccillo's recent publications reveals a strong focus on striatal circuit function across multiple dimensions. His work spans molecular neuroscience (examining synaptic adhesion molecules), cellular physiology (studying specific neuron types in striatal circuits), systems neuroscience (mapping circuit connectivity), and behavioral neuroscience (quantifying motor learning and decision-making). A unifying theme is how disruptions in specific molecular pathways lead to circuit-level abnormalities that manifest as behavioral phenotypes relevant to neuropsychiatric disorders, with particular attention to autism, OCD, and schizophrenia models. Scientific Recognition: Publications in high-impact journals including Nature Neuroscience, Current Biology, Cell Reports, and Neuron Research supported by multiple NIH grants including NIMH F32, NIMH K01, and HHMI Gilliam Fellowship awards for lab members Fuccillo actively mentors a diverse group of trainees including postdoctoral fellows, graduate students, and undergraduates. His laboratory has produced numerous successful alumni who have gone on to faculty positions, medical residencies, and graduate programs at prestigious institutions. His mentoring approach emphasizes technical skill development across multiple neuroscience disciplines while fostering independent scientific thinking. Current research in his lab is supported by NIH funding focused on understanding the molecular architecture of striatal circuits and their role in behavioral control, with three major research directions exploring molecular logic of striatal circuits, circuit mechanisms of behavioral control, and striatal dysfunction in neuropsychiatric disease models. The Fuccillo Laboratory operates within the Department of Neuroscience at the University of Pennsylvania, with access to state-of-the-art facilities for molecular, electrophysiological, imaging, and behavioral neuroscience research. The lab maintains active collaborations with other neuroscience research groups at Penn and beyond, creating a rich intellectual environment for studying the neural basis of behavior. Current research directions include investigating whether there is a molecular logic to striatal circuit composition, how striatal circuits shape behavioral control, and what mouse models of autism, schizophrenia, and OCD can reveal about striatal circuit dysfunction in disease pathophysiology.
Dr. Sabine Krabbe is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, Germany, where she leads research on neural circuit mechanisms underlying adaptive learning and state-dependent decision-making. Her work integrates neuroscience, molecular biology, and behavioral approaches to understand how internal states influence behavior and how these processes are disrupted in neurological disorders. Dr. Krabbe's research focuses on the interactions between midbrain circuits of the substantia nigra and ventral tegmental area with their output structures such as the striatum and amygdala. She investigates how these networks integrate internal states with environmental cues to produce appropriate behavioral responses. Her laboratory employs state-of-the-art techniques including deep-brain calcium imaging at single-cell resolution in mice, opto- and pharmacogenetic manipulations, anatomical tracings, and molecular approaches to characterize neural circuit elements in detail. Her recent publications reveal significant insights into amygdala interneuron plasticity during fear learning, brain-wide representational drift in memory consolidation, and the molecular mechanisms underlying Parkinson's disease progression. Her work demonstrates how activity patterns within specific neural circuits change in early stages of neurodegenerative diseases and how this dysfunction contributes to cognitive deficits and emotional disturbances. Dr. Krabbe is actively involved in the neuroscience community, organizing the BonnBrain Conference 2026 and sharing research through social media platforms. She has established herself as an emerging leader in the field of systems neuroscience with a particular focus on the neural basis of emotional states and decision-making processes.
Colin J Akerman is Professor of Neuroscience and Group Leader in the Department of Pharmacology at the University of Oxford, concurrently serving as Corange Fellow and Medical Tutor at Corpus Christi College. His research investigates fundamental mechanisms of synaptic circuit formation and plasticity, with direct implications for epilepsy, dementia, and schizophrenia through multidisciplinary approaches integrating electrophysiology, optical imaging, and computational modeling. His primary research interests encompass Synaptic Plasticity, Neural Circuit Formation, and Excitatory-Inhibitory Balance, with specific focus on neuronal progenitor influences on connectivity, chloride dynamics in inhibitory transmission, and learning mechanisms in disease contexts. The lab employs custom-built equipment and molecular tools to probe synaptic function across in vivo , in vitro , and in silico platforms, emphasizing how activity-dependent processes shape neural networks during development and disease. Recent publications (2023-2025) reveal strong thematic convergence on intracellular chloride regulation in sleep-wake cycles, cortical circuit assembly from embryonic progenitors, and innovative optical tools for neural monitoring. This work bridges molecular neuroscience with systems-level understanding of synaptic plasticity, particularly regarding ionic mechanisms in epilepsy and sleep homeostasis. No scientific awards or fellowships are explicitly documented in the source materials. Professor Akerman currently mentors four PhD students (Vourvoukelis, Selfe, Wang, Gemayel) and multiple postdoctoral researchers, having previously trained scientists now leading independent groups in Toronto, Edinburgh, Cape Town, Oxford, and London. His research is funded by the European Research Council, Innovative Medicines Initiative, and Wellcome Trust, supporting investigations into synaptic mechanisms underlying neurological disorders. The Akerman Group, established in 2008, operates as an integrative neuroscience hub within Oxford's Pharmacology Department. The 10-member team combines expertise in patch-clamp electrophysiology, optogenetics, multiphoton imaging, and computational modeling, with current projects spanning neuronal progenitor biology, inhibitory synaptic plasticity, and learning rule implementation in neural networks. The lab emphasizes technical innovation, regularly developing custom instrumentation and molecular tools for neural observation and manipulation.
Dr. Hillel Adesnik is a Professor in the Department of Neuroscience at the University of California, Berkeley, and a leading researcher in the neural basis of sensory perception. His lab focuses on cortical microcircuits, optogenetics, and neural coding, with emphasis on visual processing and memory formation. Key Research Areas: Cortical Microcircuits Optogenetic Tools Gamma Band Rhythms Neural Coding Mechanisms Dr. Adesnik has pioneered high-speed optical methods like 3D-MAP and 3D-SHOT to manipulate neural activity. His work spans cortical dynamics, synaptic plasticity, and cortical layer interactions, with applications in understanding learning algorithms and sensory inference. Selected Trends from Publications: Recent preprints and papers highlight advancements in cortical VIP neuron function, channelrhodopsin structures, and inter-areal computations. His team utilizes two-photon holography, cryo-EM, and computational modeling to decode perception-related neural codes. Scientific Awards: NIH Director's New Innovator Award (2013) Dr. Adesnik's lab collaborates with institutions like NIH and develops tools for awake animal studies. Funding includes grants from the Beckman Young Investigator Program and NIH.
Kamal Sen is an Associate Professor in the Department of Biomedical Engineering at Boston University, serving as Director of the Natural Sounds and Neural Coding Laboratory and Director of Admissions and Recruitment for Master’s Programs. He holds a PhD and MA in Physics from Brandeis University and a BA in Physics from Bates College. His research focuses on understanding how neurons encode natural sounds, particularly in the auditory cortex. Key areas include neural coding efficiency, hierarchical auditory processing, and the role of learning in shaping receptive fields. He developed the BOSSA algorithm to address sound segregation challenges in noisy environments, with applications for hearing aid technology. Sen’s work integrates electrophysiological techniques with theoretical approaches from signal processing, information theory, and systems theory. His lab explores neural discrimination of behaviorally relevant sounds and models cortical processing dynamics using computational frameworks. Recent studies investigate parvalbumin neuron contributions to temporal coding and cortical noise reduction in complex auditory scenes. His publications span neural circuit modeling, fNIRS applications in BCI, and biomimetic algorithms for auditory scene analysis. Research highlights include exploring schizophrenia-related gene effects on neural circuits and developing 3D neurosphere models for Parkinson’s disease.
Larry Abbott is the William Bloor Professor of Theoretical Neuroscience at Columbia University, with joint appointments in the Department of Physiology and Cellular Biophysics (within Biological Sciences) and the Mortimer B. Zuckerman Mind Brain Behavior Institute. He serves as Co-Director of the Center for Theoretical Neuroscience and is a Senior Fellow at HHMI Janelia Farm. PhD in Physics (1977), Brandeis University His research focuses on computational and mathematical modeling of neurons and neural networks, emphasizing spike-timing-dependent plasticity, sensory encoding in olfaction, and dynamics of internally generated neural activity. He explores how chaotic neural activity is harnessed for motor output and how perception involves dynamic inference and synaptic plasticity. Recent publications highlight applications of recurrent neural networks, hierarchical control mechanisms, and sensory-motor integration. Collaborative work spans institutions like MIT, Hebrew University, and the Allen Institute for Brain Science. Awards include the NIH Director’s Pioneer Award and the Swartz Prize in Theoretical Neuroscience. NIH Director’s Pioneer Award (2004) Swartz Prize (2010) First Annual Prize in Mathematical Neuroscience (2013) Irving Institute Mentor of the Year (2013)
Michelle CD Bridi is an Assistant Professor in the Department of Neuroscience at West Virginia University School of Medicine , with a joint affiliation at the Rockefeller Neuroscience Institute . Her research integrates synaptic plasticity , sleep physiology , and neurological conditions to investigate dynamic synaptic regulation under typical and atypical states. Education: BS , McGill University, 2006 PhD , University of Pennsylvania, 2013 Research Focus: The Bridi Lab explores how daily oscillations in excitation/inhibition (E/I) balance are disrupted in Autism Spectrum Disorder (ASD) , aging , and post-stroke states . Current projects address: 1) synaptic adaptation to sleep/wake cycles, 2) E/I imbalance in neurodevelopmental disorders, and 3) molecular mechanisms maintaining neuronal firing rate homeostasis. Publication Trends: Recent work spans REM sleep plasticity , autism models , and neurodegenerative interventions , emphasizing synaptic oscillations , NMDA receptor pathways , and gene therapy applications. Collaborative efforts with Morgan Bridi's lab extend findings to stress and stroke contexts. Grants & Collaborations: Research is funded by NIH/NIGMS , BBRF , and NSF . The lab actively collaborates with cross-institutional teams and is recruiting postdocs and students for ongoing studies.
Dr. Nika Danial is an Associate Professor of Cell Biology at Harvard Medical School and the Department of Cancer Biology at Dana-Farber Cancer Institute. She leads the Danial Lab, investigating metabolic mechanisms that regulate cellular adaptation to stress, with a focus on fuel utilization in health and disease. Dr. Danial holds additional roles as Co-Director of the NCI-funded T32 Training Program in Cancer Chemical Biology and Metabolism. Her research integrates biochemistry, mouse models, and metabolomics to study metabolic contributions to cancer, diabetes, and neurological disorders. Education: PhD from Columbia University (1999), postdoctoral training at Harvard Medical School and Dana-Farber under Dr. Stanley Korsmeyer. Key research areas include mitochondrial dynamics, glucose metabolism pathways, and the interplay between inflammation and metabolic signaling. The lab has pioneered studies on how metabolic flexibility impacts disease progression in pancreatic islets, lymphoma subtypes, and neuronal excitability. Publications highlight discoveries in mitochondrial fatty acid oxidation regulation, urea cycle anti-inflammatory mechanisms, and metabolic signatures in cancer subtypes. Her work has implications for developing therapies targeting metabolic vulnerabilities in diseases like diffuse large B-cell lymphoma and type 1 diabetes. The Danial Lab emphasizes rigorous training for the next generation of scientists through mentorship programs and interdisciplinary collaboration.
Professor David Dupret is a Professor of Neuroscience and MRC Investigator at the University of Oxford, where he also serves as a Tutorial Fellow in Biomedical Sciences at St Edmund Hall. His work takes place within the MRC Brain Network Dynamics Unit, part of the Nuffield Department of Clinical Neurosciences, and he is affiliated with the Department of Physiology, Anatomy and Genetics. David completed his Ph.D. in Neuroscience at the Institute François Magendie (INSERM, University of Bordeaux, France), receiving the French Neuroscience Association's 2007 Ph.D. Year Prize. He joined the MRC Anatomical Neuropharmacology Unit in 2007 as a Visiting Fellow, funded by the Institute of France and the International Brain Research Organisation. In 2009, he became an MRC postdoctoral scientist and Junior Research Fellow at St Edmund Hall, progressing to MRC Programme Leader Track scientist in 2011 and tenured MRC Programme Leader in 2014. Professor Dupret's research focuses on the circuit-level mechanisms of memory-guided behavior, with particular emphasis on neural dynamics of memory circuits during active waking behavior and sleep. His laboratory employs in vivo multichannel recordings and optogenetic manipulation of neuronal ensembles to investigate how hippocampal networks organize memory processes. His work has revealed fundamental insights into how memory circuits operate during both waking behavior and sleep states, particularly regarding hippocampal ripple activity, dentate spikes, and offline reactivation processes. Analysis of Professor Dupret's recent publications reveals a consistent focus on hippocampal network dynamics and memory processes. His work spans from basic neural circuit mechanisms to applications in neurodegenerative conditions like Alzheimer's disease. A notable trend is the integration of computational approaches with experimental neuroscience to understand how neural assemblies encode and retrieve memories. His team has made significant contributions to understanding how dentate spikes support memory flexibility and how hippocampal ripple diversity organizes neuronal reactivation during offline states. French Neuroscience Association's 2007 Ph.D. Year Prize Foundation Louis D. Research Fellowship (2007) International Brain Research Organisation Fellowship (2008) FENS-Kavli Network of Excellence Scholar (2016) Boehringer Ingelheim-FENS Research Award (2018) Elected to membership of Academia Europaea (2024) Professor Dupret has secured substantial research funding through his MRC Programme Leader position and has mentored numerous researchers who appear as co-authors on his publications. His laboratory, the Dupret Group, operates within the MRC Brain Network Dynamics Unit, collaborating extensively with other research groups including the Sharott Group, Magill Group, and Denison Group. Current research directions include investigating how memory circuits maintain flexibility while resisting extinction, exploring the relationship between neural coactivity patterns and memory organization, and developing computational models of hippocampal function. His team is actively pursuing future work on the mechanisms underlying memory persistence and the neural basis of flexible memory recall.
Andrew J. Todd is a Professor and Honorary Fellow in the School of Psychology & Neuroscience at the University of Glasgow. His research focuses on neurochemistry and synaptic connections in the mammalian spinal cord, particularly the organization of neuronal circuits underlying pain and itch perception. He employs techniques like immunocytochemistry, confocal microscopy, and electron microscopy. Collaborations include researchers from institutions such as UCL, Saga University, and the University of Pittsburgh. His work is funded by the Wellcome Trust and BBSRC. Roles: Professor, Honorary Fellow Affiliations: School of Psychology & Neuroscience, University of Glasgow Research Interests Dr. Todd investigates spinal dorsal horn circuits, including projection neurons, interneurons, and synaptic plasticity. Key topics include: Neurochemical characterization of spinal neurons Role of neuropeptides like substance P and gastrin-releasing peptide Mechanisms of neuropathic pain and spinal circuit adaptations Functional roles of specific neuron populations in laminae I-III Articles Overview Recent work includes studies on spinal projection neuron markers (e.g., Tacr1, Gpr83), synaptic circuits involving GRP-expressing neurons, and interneuron subtypes' roles in pain/itch. Notable findings include the absence of neuronal loss in neuropathic pain models and the identification of novel spinal circuits. Grants & Funding Funded by the Wellcome Trust and BBSRC . Collaborations span international institutions, emphasizing spinal neurobiology and sensory processing.
Dr. Conny Kopp-Scheinpflug is an Associate Professor (PD) at the Faculty of Biology, Ludwig Maximilian University of Munich, where she leads a research group focused on auditory neuroscience. Her laboratory investigates the function and mechanisms of activity-dependent neuromodulation in the mammalian auditory system, with particular interest in how ambient sensory stimulation activates neuromodulators and how these influence neural processing of relevant information. Dr. Kopp-Scheinpflug's research spans auditory neuroscience, neuromodulation, neuronal excitability, and synaptic transmission. She employs electrophysiological (single cell in vivo and patch clamp in brain slices), anatomical, and optogenetic techniques to study how hyper- or hypo stimulation lead to acquisition or loss of function in the auditory system. Her work has significant implications for understanding and potentially treating functional disorders of neuronal excitability. Current research examines potassium channels, nitric oxide signaling, and neuromodulators like urocortin 3 in auditory processing. Analysis of Dr. Kopp-Scheinpflug's recent publications (2016-2022) reveals consistent focus on auditory processing mechanisms, particularly potassium channels (Kv3.1, Kv3.3, Kv1.1), nitric oxide signaling, and activity-dependent changes in myelination. Her research spans molecular mechanisms to systems-level auditory processing, with emphasis on sound localization, temporal processing, and recovery from hearing impairment. Key findings include how sound-evoked activity influences myelination, how nitric oxide regulates postsynaptic excitability, and how urocortin 3 aids hearing recovery. Dr. Kopp-Scheinpflug has secured funding from multiple research agencies. She maintains active collaborations with researchers at Lehigh University (Michael Burger Lab), University of Edinburgh (Matthias Hennig Lab), Ben-Gurion University of the Negev (Michal Hershfinkel Lab), and UCL (Dr. Jennifer Linden). Her laboratory currently includes Ezhilarasan Rajaram, Dr. Mihai Stancu, Oskar Kalle Juhani Markkula, Sara Pagella, and Katharine Krueger. Past lab members who have completed their training include Dr. James Sinclair, Dr. Matthew Fischl, Max Bayer, Alkmini Damkou, Alyahyay Mansour, Leander Mrowka, Joseph Kroeger, and Myriam Schmidt-Pauly.
Sebastian Seung is a Professor at Princeton University , affiliated with both the Department of Computer Science and the Princeton Neuroscience Institute . His career spans Harvard University (Ph.D., 1990), Bell Laboratories, and Massachusetts Institute of Technology before joining Princeton in 2014. An External Member of the Max Planck Society and 2008 Ho-Am Prize recipient, Seung merges machine learning with neuroscience . Research Focus : Pioneering connectomics , Seung developed technologies for reconstructing neural circuits from high-resolution brain images, including FlyWire for collaborative brain mapping. His work explores brain function, development, and plasticity , drawing parallels between fly visual systems and convolutional networks . Awards & Affiliations : 2008 Ho-Am Prize in Engineering External Member, Max Planck Society Technical Contributions : Led breakthroughs in 3D connected component labeling and high-throughput EM imaging for mammalian brains, partnering with NIH’s BRAIN Initiative to scale connectomics to whole mouse brains. Seung’s team has shifted from EM analysis to interpreting connectomes , focusing on neural circuit function and biological mechanisms in flies and mice. His lab alumni network spans institutions, advancing AI and neuroscience globally.
Anne Schaefer is a Full Professor with Tenure at the Mount Sinai School of Medicine, currently serving as Managing Director at the Max Planck Institute for Biology of Ageing in Cologne, Germany. She co-directs the Center for Glial Biology within the Friedman Brain Institute, focusing on neuroscience and psychiatry. Education: Charité University Berlin (MD/PhD), Johannes Gutenberg University Mainz (undergraduate) Research Interests: Schaefer’s work bridges neuroscience , neuroimmunology , and epigenetics , with a primary focus on microglial biology, neuronal activity regulation, and mechanisms underlying neurodegeneration. Her studies explore how microglia interact with neurons to maintain brain homeostasis and drive plasticity. Scientific Awards: Max Planck Sabbatical Award (2019) Inaugural NINDS Landis Award for Outstanding Mentorship (2018) NIH Director’s New Innovator Award (2012) Kavli Frontiers in Science Fellow (2014) German Research Foundation DFG Research Fellowship (2006–2008) Summa cum laude, Charité University Berlin (2004) Grants & Funding: Schaefer has secured significant third-party funding, including an ERC Synergy Grant (2021–2027) for the project "Micro-'COPS' - Microglia-control of physiological brain states." Labs & Teams: She leads a research team at the Max Planck Institute for Biology of Ageing and collaborates closely with the Center for Glial Biology at Mount Sinai, where she has held leadership roles since 2017.
