جست‌وجوی استاد و پژوهشگر

• Alzheimer's disease
• Neuroimaging
• Neuroinflammation
• +۶ مورد دیگر

Anne Maass is a Researcher at the German Center for Neurodegenerative Diseases (DZNE), Magdeburg , leading multidisciplinary studies at the intersection of Alzheimer's disease , neuroimaging , and cognitive resilience . Her work focuses on molecular mechanisms of aging using in vivo multimodal imaging techniques. Key affiliations: DZNE Magdeburg, Otto von Guericke University, SFB1436 "Neural Resources of Cognition" Collaboration network: Prof. Emrah Düzel (Magdeburg), Prof. Michael Heneka (Bonn), Prof. Stefanie Schreiber (Magdeburg), Prof. Sylvia Villeneuve (Montreal) Her research integrates functional and structural MRI (3T/7T) , PET imaging with novel tracers like PI-2620 , and cerebrospinal fluid proteomics to map tau pathology , Aβ accumulation , and vascular contributions to cognitive decline. She pioneered Vessel Distance Mapping for quantitative hippocampal vascularization analysis. Recent publication trends emphasize inflammatory signatures (TAM receptors, sTREM2), non-linear fMRI activation patterns in preclinical Alzheimer's, and vascular compensation mechanisms for neurodegenerative pathology. Her work on SuperAgers investigates neural resources for exceptional cognitive aging through multimodal cohort studies. Current projects include: SFB1436 Z03 : Molecular imaging of aging and SuperAgers DELCODE study : Longitudinal tracking of Alzheimer's biomarkers Collaborative network : Cross-site studies with Bonn, Göttingen, and Barcelona Her translational research aims to develop intervention strategies for neuroinflammatory regulation and cognitive reserve enhancement to prevent age-related cognitive decline.

Svetlana N. Radyukمشاهده پروفایل

استاد پژوهشی

• Redox Regulation
• Innate Immunity
• Aging Mechanisms
• +۵ مورد دیگر

Svetlana N. Radyuk serves as a Research Associate Professor in the Department of Biological Sciences within Dedman College of Humanities and Sciences at Southern Methodist University. Her laboratory (DLSB 317) focuses on the molecular mechanisms linking redox regulation, innate immunity, and aging processes using Drosophila melanogaster as a primary model system. Her research centers on redox regulation of innate immunity during aging , specifically investigating how peroxiredoxins modulate immune responses and longevity. Key areas include: Role of reactive oxygen/nitrogen species (ROS/RNS) as dual-function molecules causing tissue damage while serving as immune signaling messengers Conserved functions of peroxiredoxins across biological kingdoms in regulating redox homeostasis Age-related immune decline including reduced pathogen resistance, impaired T/B cell function, and chronic inflammation Interactions between circadian clocks, redox balance, and aging processes Analysis of her 15 most recent publications reveals a consistent focus on peroxiredoxin-mediated redox signaling in Drosophila models, with recent expansion into hydrogen gas therapeutics for oxidative stress-related conditions. Her work demonstrates how precise ROS/RNS regulation balances immune protection against tissue damage, with significant implications for age-related diseases. Dr. Radyuk currently holds two major NIH/NIA-funded research grants: R01 AG032342 (Principal Investigator): Peroxiredoxins, immune signaling and aging (2011-2016) R01 AG045830 (Co-PI): Circadian clocks and aging (2013-2018) Her teaching portfolio includes advanced courses in Immunobiology (BIOL 4319), Molecular Genetics Laboratory (BIOL 3222), and graduate-level research/thesis supervision (BIOL 6270, 8398). Her laboratory employs comprehensive molecular biology and genetics techniques to investigate redox-immunity interactions, with particular emphasis on developing interventions that maintain optimal immune function during aging.

Ryan O'Connellمشاهده پروفایل

استاد

• Noncoding RNAs
• Inflammation
• Cancer
• +۳ مورد دیگر

Ryan O'Connell is a Professor in the Department of Pathology at the University of Utah and Chief of Microbiology and Immunology. His research laboratory is located at the Huntsman Cancer Institute. He also serves as Co-Director of the Immunology, Inflammation and Infectious Disease (3i) Initiative, Associate Chief of the Microbiology and Immunology Division, and Program Co-Director of the Neuroimmunology Training Grant. Education: B.S. California Lutheran University Ph.D. University of California, Los Angeles Research Interests: Dr. O'Connell's research focuses on the roles of microRNAs (miRNAs) in regulating both physiological and pathological immune cell functions in mammals, with an emphasis on inflammation and cancer. His laboratory is currently investigating: Communication between the mammalian host and gut microbiota via extracellular vesicles and their RNA cargo during inflammatory bowel disease (IBD) and colorectal cancer (CRC) The role of miRNAs in coordinating antitumor and immunotherapeutic responses to gastrointestinal (GI) and blood cancers Development and mechanistic study of mRNA vaccines to induce immunity against GI and blood cancers Interplay between miRNAs and cellular metabolism during age-related inflammation and cancer Publications: Dr. O'Connell has published over 100 high-impact primary research manuscripts and review articles. His recent work spans diverse areas including cancer immunotherapy, microbiota interactions, metabolic regulation in immune cells, and the development of bioinformatics tools for cancer genomics. Leadership and Mentorship: He has mentored 14 graduate students (including 4 MD/PhD students) and 6 postdoctoral scholars, many of whom have advanced to positions in academia and industry. His leadership roles include directing major initiatives in immunology and inflammation research at the University of Utah.

• Air pollution exposure assessment
• Particulate matter characterization
• Low-cost sensor technology
• +۶ مورد دیگر

Richard E. Peltier, MPH, PhD, is an Assistant Professor of Environmental Health Sciences in the School of Public Health & Health Sciences at the University of Massachusetts Amherst, where he directs an exposure-assessment laboratory focusing on air pollution, sensor technology and environmental justice. Education & Training: Details of degrees not explicitly listed in the supplied text, but he holds MPH and PhD credentials. Research Interests: Peltier’s work integrates low-cost aerosol sensors, mobile monitoring platforms and advanced chemical speciation to quantify fine particulate matter, black carbon, wood smoke tracers and heavy metals across diverse environments—from NYC subways and NJ harbour to Indigenous sub-arctic communities and megacities in Nepal and India. He couples these measurements with epidemiological indicators such as respiratory inflammation, blood pressure and oxidative stress to illuminate exposure–response relationships and to inform environmental-justice policy. Publication Trends: Across 40+ peer-reviewed articles (2008-2023) his research exhibits a clear trajectory: early method development for PM chemical characterization (nickel/vanadium from residual oil, traffic tracers, organosulfates) → deployment of high-time-resolution sensors in complex urban sources → health-impact studies in vulnerable populations → intervention evaluation (cloth masks, respirator decontamination, hookah ventilation). Recent outputs increasingly frame findings within environmental-justice contexts, advocating for evidence-based policy at EPA and global agencies. Funding & Grants: While specific grant numbers are not listed, Peltier is identified as PI or co-I on projects supported by NSF, NIH, the Health Effects Institute and Massachusetts state agencies, indicating a robust externally funded research program. Laboratory & Teams: He leads the Peltier Exposure Assessment Lab located in 149E Goessmann Laboratory, UMass Amherst, which maintains state-of-the-art aerosol instrumentation and mentors graduate and undergraduate students in environmental health sciences.

Shilin Zhaoمشاهده پروفایل

استادیار

• Artificial Intelligence in Digital Pathology
• Spatial Transcriptomics Analysis
• Kidney Disease Morphomics
• +۴ مورد دیگر

Shilin Zhao is an Assistant Professor of Biostatistics at Vanderbilt University Medical Center, specializing in artificial intelligence applications for digital pathology and multi-omics integration. His work bridges computational methodology development with clinical pathology to address challenges in kidney disease, gut microbiome research, and metabolic disorders. Education PhD in Bioinformatics, Shanghai Institutes for Biological Sciences Research Focus Dr. Zhao's research centers on AI-driven pathology and spatial omics , with primary emphasis on: Glomerular and kidney layer segmentation using cross-species data integration Foundation model assessment for cell nuclei analysis in renal histopathology Multi-omics approaches to colitis, atherosclerosis, and metabolic diseases Development of graph networks for spatial transcriptomics prediction His methodologies frequently combine deep learning with biostatistical rigor to translate computational insights into clinical pathology applications. Publication Trends Dr. Zhao's 2025 publications demonstrate intense focus on AI pathology tools (14/15 articles), particularly glomerular analysis and spatial transcriptomics. Key themes include cross-species model adaptation (GLAM), multi-level attention networks (MagNet), and clinical validation of AI foundation models in kidney pathology. His work consistently targets diagnostic precision through computational innovation. Scientific Recognition No specific awards or honors were documented in the provided materials. Academic Contributions While student advising details are unavailable, Dr. Zhao actively contributes to methodological advances in biostatistics through high-impact publications. His involvement in the KPIS 2024 challenge indicates leadership in establishing glomerular segmentation benchmarks for the pathology AI community. Research Environment As primary faculty in Vanderbilt's Department of Biostatistics, Dr. Zhao likely collaborates with institutional resources including the Vanderbilt Biostatistics Data Coordinating Center (VBDCC) and Vanderbilt Technologies for Advanced Genomics Analysis and Research Design (VANGARD), though specific affiliations aren't explicitly stated.

Junzhong Xuمشاهده پروفایل

دانشیار

• Quantitative MRI Methods
• Neurodegenerative Diseases
• Cancer Imaging
• +۳ مورد دیگر

Junzhong Xu is an Associate Professor of Radiology and Radiological Sciences, Biomedical Engineering, and Physics and Astronomy at Vanderbilt University. His research focuses on developing advanced quantitative MRI methods for applications in neurodegenerative diseases and cancer, including MRI cell size imaging and tumor treatment response assessment. He holds affiliations with the Vanderbilt University Institute of Imaging Science (VUIIS) and has expertise in microstructural diffusion MRI and GPU-accelerated imaging tools. Xu’s work spans interdisciplinary collaborations in biomedical engineering and physics. Education: B.S., University of Science and Technology of China M.S., University of Science and Technology of China Ph.D., Vanderbilt University Research Interests: Development of MRI cell size imaging for cancer and neurodegenerative diseases Quantitative assessment of tumor microstructure and treatment response Applications of microstructural diffusion MRI in multiple sclerosis and oncology Key Contributions: Advancement of MRI cytometry for non-invasive disease assessment GPU-accelerated tools for diffusion MRI simulation (MATI) Imaging biomarkers for early detection of neurodegenerative pathology Labs/Teams: Active member of the Vanderbilt University Institute of Imaging Science (VUIIS), collaborating on interdisciplinary imaging projects.

• Bitter Taste
• Food Chemistry
• Pharmacology
• +۷ مورد دیگر

Veronika Somoza is a University Professor at the University of Vienna , affiliated with the Faculty of Chemistry and the Centre for Microbiology and Environmental Systems Science . Her research focuses on Bitter Taste , Food Chemistry , and Pharmacology , particularly exploring interactions between taste receptors and bioactive compounds. Key Research Areas Bitter Taste Receptors (TAS2R4, TAS2R43, TAS2R16) Gastric Acid Secretion Serotonin Release Plant-Derived Compounds (Resveratrol, Nonivamide, Capsaicin) Mass Spectrometry Imaging Scientific Awards AGFD Fellow Award 2020 Her work spans Gastric Physiology , Food Toxicology , and Sustainable Nutrition , aligning with UN Sustainable Development Goals. Recent publications highlight LA-ICP-MS imaging for zinc mapping and AFM probing of bitter peptide interactions. She has also contributed to understanding Chlorogenic Acid and Advanced Glycation End-Products in food science. Veronika Somoza actively participates in scientific communication , including invited talks on flavor research and media engagement on food chemistry topics.

Malcolm Madenمشاهده پروفایل

استاد

• Developmental Biology
• Regenerative Medicine
• Retinoic Acid Signaling
• +۵ مورد دیگر

Malcolm Maden is a Professor in the Department of Biology, College of Liberal Arts and Sciences at the University of Florida. He is based in Bartram Hall and the Cancer & Genetics Research Complex in Gainesville, Florida. Research Interests Developmental and regenerative biology of limb, lung, skin, and nervous system Retinoic acid signaling in pattern formation and regeneration Comparative regeneration using axolotls and spiny mice (Acomys cahirinus) Scar-free wound healing and multi-tissue regeneration in mammals His overarching hypothesis is that regeneration recapitulates development and can be enhanced by re-activating embryonic signaling pathways, especially those mediated by retinoic acid. Publication Trends From 2020 to 2025 Maden has published extensively on the spiny mouse as a novel mammalian model for regeneration. His articles explore spinal cord recovery, cardiac repair, skin and appendage regeneration, neural stem cell abundance, and aging-related changes. A consistent theme is the comparison between scar-forming (mouse) and scar-free (spiny mouse) responses, illuminating molecular targets for therapeutic intervention. Laboratory & Affiliations Principal Investigator, Maden Laboratory, University of Florida Affiliate, Cancer & Genetics Research Complex Member, College of Liberal Arts and Sciences

• Neutrophils
• Inflammation
• Metainflammation
• +۴ مورد دیگر

Sofia de Oliveira is Assistant Professor in the Departments of Developmental & Molecular Biology and Medicine (Hepatology) at Albert Einstein College of Medicine. Her research investigates neutrophil biology in disease contexts, particularly how metainflammation and inflammaging alter neutrophil responses in liver disease, polytrauma, and aging. The lab employs zebrafish models for live imaging of immune processes. Research examines neutrophil roles in NAFLD-associated liver cancer progression, age-related immune decline, and posttraumatic inflammation. Projects integrate immunology, metabolism, and disease modeling to identify therapeutic targets. Publications establish zebrafish as key model for visualizing neutrophil dynamics and demonstrate metformin's immunomodulatory effects in liver disease. Current work explores neutrophil heterogeneity in aging and metabolic syndrome contexts.

• Lipid Metabolism
• Cholesterol Homeostasis
• Nuclear Receptors
• +۵ مورد دیگر

Peter Tontonoz is a Professor at the University of California Los Angeles, jointly appointed in the Department of Pathology and Laboratory Medicine and the Department of Biological Chemistry. His research integrates molecular biology, metabolism, and immunology to study lipid homeostasis, nuclear receptor signaling (LXRs/PPARs), and metabolic diseases. With over 350 publications, he leads pioneering work on cholesterol transport, adipocyte biology, and atherosclerosis. His research focuses on: Regulation of cholesterol flux via nonvesicular transport pathways (e.g., Aster proteins) Transcriptional control of lipid metabolism by LXRs and PPARs Adipocyte differentiation and thermogenic programming Inflammatory mechanisms linking lipid disorders to atherosclerosis Recent articles (2022–2025) emphasize membrane lipid remodeling, organelle interactions, and sex-specific metabolic regulation. Key trends include: Mechanistic studies on phospholipid-protein interactions in mitochondria/ER Cholesterol-driven inflammation in vascular and neurological contexts PPAR isoform-specific roles in liver/adipose tissue adaptation

Beckie Ingramمشاهده پروفایل

دانشیار

• Immunology
• Microbiology
• Vaccine Development
• +۷ مورد دیگر

Dr Beckie Ingram serves as a Reader at the Wellcome Wolfson Institute for Experimental Medicine within the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast. Her research program focuses on understanding lymphocytic responses to bacterial infections to facilitate rational vaccine design, with particular expertise in in vivo murine bacterial infection models that form the cornerstone of her laboratory's technical capabilities. Her research program spans several interconnected areas: The induction of innate immunological memory against bacterial infection Identification of bacterial antigens from Pseudomonas and Anthrax that elicit protective memory T cell responses Defining the precise role of T cells in both driving and resolving inflammation during Streptococcus and Pseudomonas infections The rational design and optimization of pre-clinical models to test novel antimicrobials and investigate complex host-pathogen interactions Analysis of her publication trajectory since 2008 reveals a consistent research program with significant contributions to understanding immune responses to bacterial pathogens. Her most recent work examines ageing effects on regulatory T cells in central nervous system remyelination (2024), while earlier landmark studies include research on anthrax immunity mechanisms and innovative antimicrobial delivery systems using nanoparticle technology. Dr Ingram's scholarly contributions have been recognized through several prestigious awards: Aurora – Developing women leaders in higher education (2017) Best Poster Prize (March 2015) Immunology Research Prize (August 2015) NC3Rs prize for reduction of animal research (April 2022, with Marshall, H.) NC3Rs prize (May 2023, with Zarodkiewicz, P.) She currently serves as Co-Investigator on multiple significant research grants including NICOLA-biome: The NICOLA gut microbiome databank (2025-ongoing), High Parameter Flow Cytometry in Health and Disease (2019-ongoing), and Inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis (2015-ongoing). Her scholarly engagement extends to extensive peer review activities, with recent invited talks on Pseudomonas and Klebsiella vaccine development (April 2024), and active participation in science outreach through school visits and the Northern Ireland Science Festival (February-March 2024). Her laboratory at the Wellcome Wolfson Institute maintains specialized expertise in murine infection models to investigate host immune responses to bacterial pathogens, with particular emphasis on T cell responses to Pseudomonas aeruginosa and Bacillus anthracis , contributing to the UN Sustainable Development Goals related to good health and well-being.

Stephen Ramseyمشاهده پروفایل

دانشیار

• Computational Systems Biology
• Bioinformatics
• Precision Medicine
• +۶ مورد دیگر

Stephen Ramsey, an Associate Professor at Oregon State University, holds dual appointments in the School of Electrical Engineering and Computer Science (College of Engineering) and the Department of Biomedical Sciences (Carlson College of Veterinary Medicine). With a PhD in Physics from the University of Maryland, his postdoctoral training in computational genomics at the University of Washington, and professional experience at the Institute for Systems Biology and Center for Infectious Disease Research, Ramsey bridges computational methods with biomedical applications. Education : Ph.D., Physics, University of Maryland; M.S., Physics, University of Maryland; Sc.B., Mathematical Physics, Brown University Ramsey specializes in computational systems biology , focusing on bioinformatics , biomedical knowledge graphs , and precision medicine . His research integrates machine learning , gene regulatory network modeling , and multi-omics data analysis to address challenges in rare disease diagnostics , drug monitoring , and inflammatory disease mechanisms . Current work includes AI-driven biomedical translation and electrochemical biosensor development for non-invasive diagnostics . Recent publications highlight knowledge graph applications in translational biomedicine , causal network inference in clinical-environmental data integration , and cross-species cancer transcriptomics . His team develops tools like RTX-KG2 and PloverDB to standardize biomedical data sharing and semantic reasoning . Scientific Awards : 2019 Zoetis Award (Carlson College of Veterinary Medicine) 2016 NSF CAREER Award 2016 PhRMA New Investigator Award 2010 NIH K25 Mentored Quantitative Research Award Ramsey advises in computational biology courses (CS 446/546) and contributes to biomedical AI through projects like mediKanren for rare disease diagnostics . His NSF-funded research explores gene expression noise and regulatory network dynamics , while NIH and PhRMA grants support his translational medicine initiatives. He leads the Ramsey Laboratory , which develops graph-based reasoning tools for biomedical data translation and multi-omics integration . The lab's work spans comparative oncology models, electrochemical biosensors , and knowledge graph infrastructure for clinical decision support .

Sarah Spencerمشاهده پروفایل

استاد

• Neuroimmunology
• Brain Inflammation
• Alzheimer’s Disease
• +۵ مورد دیگر

Professor Sarah Spencer is an internationally recognized neuroendocrinology researcher at RMIT University’s School of Health and Biomedical Sciences. She holds a BSc (Hons) from Otago University (New Zealand) and a PhD from The University of Queensland (Australia). Her research explores how lifestyle factors like diet influence brain inflammation and associated diseases, with a focus on Alzheimer’s early detection, retinal microglia imaging, glial scarring, and post-SARS-CoV-2 mental health impacts. She has held postdoctoral roles at Calgary University (Canada) and Monash University (Australia) and is currently a top 1% cited scientist (Scopus). Her work integrates neuroimmunological, developmental, and stress physiology approaches to unravel disease mechanisms. Her research portfolio includes over 50 peer-reviewed articles, with projects funded by organizations like AHURI, CSIRO, and the Victorian Government. Teaching interests emphasize translational research in neuroimmune disorders and evidence-based practice. She actively supervises postgraduate research students in areas ranging from brain regeneration to dietary interventions in cognitive decline.

• Medical Imaging
• Bioengineering
• Cardiovascular Hemodynamics
• +۶ مورد دیگر

Patrick Winter is a Senior Lecturer I in the Department of Bioengineering at the Erik Jonsson School of Engineering and Computer Science, University of Texas at Dallas. His research focuses on advanced MRI techniques, cardiovascular imaging, and nanotechnology applications in molecular imaging. He specializes in developing imaging methodologies for diagnosing vascular diseases like atherosclerosis and aneurysms, with particular emphasis on 4D flow MRI, deep learning algorithms, and nanoparticle-based theranostics. Educations: No formal education details provided in text. Research Interests: His work bridges bioengineering and clinical medicine, addressing challenges in non-invasive disease detection. Key areas include: Development of super-resolution MRI techniques Machine learning applications in medical imaging Targeted nanoparticle delivery systems Quantitative hemodynamic analysis Preclinical cardiovascular modeling Recent articles highlight innovations in: Deep learning-enhanced 4D flow MRI for stroke prediction Ensemble learning for cardiovascular system imaging Multi-modal imaging of aneurysm dynamics Awards: No scientific awards explicitly mentioned in provided texts. Grants/Advising: No grant details or student advisees listed. Collaborations likely focus on interdisciplinary cardiovascular research. Labs/Teams: Engaged in bioengineering labs specializing in MRI technology advancement and nanomedicine applications.

Ingo Schiesslمشاهده پروفایل

مدرس ارشد

• Neuroscience
• Neurovascular Coupling
• Optical Imaging
• +۷ مورد دیگر

Ingo Schiessl is a Senior Lecturer in the Division of Neuroscience at the University of Manchester. He holds an ORCID identifier (0000-0001-9599-6194) and has a permanent teaching and research position since 2003. His academic journey includes a BSc and MSc in Physics from the University of Regensburg, followed by medical physics training at a university hospital in Germany. He completed a PhD in neuroscience through a collaboration between the Technical University of Berlin and University College London (UCL). Research Interests: High-resolution functional imaging of neuro-vascular changes in preclinical brain disease models Multi-wavelength optical imaging with electrode and tissue oxygen recordings Key Projects: Neuroinflammation (collaborative research on brain function and translational studies) Brain disorders (focused on Parkinson's disease and stroke mechanisms) Expertise aligns with UN Sustainable Development Goals related to health and well-being. His work involves neurovascular coupling studies, blood-brain barrier mechanisms, and imaging techniques. Recent collaborations span Germany, the UK, and France.