جست‌وجوی استاد و پژوهشگر

Lili Tangمشاهده پروفایل

استاد

• Environmental Health
• Toxicology
• Neurobiology
• +۷ مورد دیگر

Lili Tang is a Professor in the Department of Environmental Health Science at the University of Georgia's College of Public Health. Her research focuses on environmental toxicants, mycotoxin exposure, and their impacts on human health, particularly neurodegenerative diseases and gut-brain interactions. She employs Caenorhabditis elegans , rodents, and advanced analytical techniques to study mechanisms of toxicity and potential therapeutic interventions. Key areas of expertise include: (1) Mycotoxin-induced neurotoxicity (aflatoxins, fumonisins), (2) PFAS neurodevelopmental effects, (3) Gut microbiota interactions with environmental contaminants, (4) High-throughput toxicity screening, and (5) Neuroprotective roles of natural compounds like green tea polyphenols. Her work spans laboratory models to human population studies in regions like Uganda and Texas. Notable platforms include use of C. elegans for rapid toxicity assessment, metabolomics approaches, and AI-driven analysis. She collaborates on projects involving aflatoxin mitigation strategies, PFAS exposure monitoring, and translational research bridging basic science and public health applications. Active in teaching environmental health science courses and advising research teams in toxicology and molecular biology.

• Machine Learning
• Computational Neuroscience
• Data Science
• +۳ مورد دیگر

UnivProf. Dr. Fabian Sinz is a Professor at the Institute of Computer Science, University of Göttingen, heading the Machine Learning group. His research focuses on interdisciplinary applications of machine learning in computational neuroscience, data science, and neuroscience. He teaches courses such as Data Science I and leads seminars on Machine Learning and Computational Neuroscience. His work bridges theoretical machine learning with empirical neuroscience, particularly in modeling neural activity and connectomics. Research interests include neural population coding, generative models for neural data, and applying machine learning to understand brain function. Notable contributions involve developing methods like TRACE and NEURD for analyzing neural datasets and predicting visual cortex responses. Recent publications emphasize foundational models for neural activity prediction and cross-modal learning. Dr. Sinz collaborates on large-scale projects like the Dynamic Sensorium Competition, advancing reproducibility in predictive modeling of brain activity. He has advised on machine learning applications in health informatics and biomechanical reconstruction. His lab’s work frequently intersects with computer vision, computational biology, and neuroimaging technologies.

Rogerio Soaresمشاهده پروفایل

استادیار

• Cardiovascular Physiology
• Exercise Physiology
• Diabetes
• +۳ مورد دیگر

Rogerio Soares is an Assistant Professor of Exercise & Sport Science at Wayne State University. His research focuses on cardiovascular and metabolic function in individuals with diabetes, aging, and cardiovascular risk factors. He teaches courses such as Exercise Physiology II and Professional Seminar . Education Doctorate of Philosophy in Kinesiology (Health and Exercise Physiology), University of Calgary (2019) Master of Science in Nutrition, Universidade Federal de Pelotas (2015) Bachelor of Science in Physical Education, Universidade Federal de Pelotas (2011) His expertise includes skeletal muscle oxygenation , microvascular function assessment , and vascular insulin sensitivity . His laboratory employs techniques such as near-infrared spectroscopy (NIRS), flow-mediated dilation (FMD), and ex vivo vascular analysis to study mechanisms in diabetes, insulin resistance, and aging. Recent publications highlight his work on sex differences in vascular adaptations , effects of dietary interventions on arterial stiffness, and molecular pathways in endothelial dysfunction. His research spans human clinical studies, animal models, and cellular mechanisms. Scientific Awards CAPES Scholarship Dr. Soares investigates how conditions like hyperglycemia, obesity, and aging disrupt vascular and metabolic health. His team also explores therapeutic strategies such as glycocalyx restoration and nitrate supplementation to mitigate these effects. He works with both human subjects and mouse models to bridge translational gaps in cardiovascular disease research.

Keri Martinowichمشاهده پروفایل

دانشیار

• Translational Neuroscience
• Neuropsychiatric Disorders
• Gene Expression
• +۱۲ مورد دیگر

Keri Martinowich is a Senior Investigator and Director of Translational Neuroscience at the Lieber Institute for Brain Development (LIBD) and an Associate Professor in the Departments of Psychiatry and Neuroscience at Johns Hopkins University School of Medicine. She leads an interdisciplinary research program focused on understanding molecular and genetic mechanisms underlying neuropsychiatric disorders such as schizophrenia, depression, PTSD, and autism. Her research integrates animal models with human postmortem brain studies, using advanced techniques including single-nucleus and spatially resolved transcriptomics, viral transgenesis, and circuit-level manipulation to identify cell-type-specific gene expression patterns and their functional roles in behavior. Her lab develops open-access tools for data exploration and emphasizes reproducibility and data sharing. Dr. Martinowich's recent publications reveal trends across cognitive and computational neuroscience, with a strong emphasis on neural circuits, gene regulation, and translational psychiatry. Her work spans molecular neuroscience, systems-level analysis, and behavior, often focusing on BDNF signaling, fear, social behavior, and cortical-subcortical circuitry. She actively mentors graduate students and postdoctoral researchers, many of whom have advanced to PhD programs and faculty positions. Electrophysiology and attention circuits (locus coeruleus–prefrontal cortex) Spatial transcriptomics in human brain regions (locus coeruleus, prefrontal cortex) BDNF mechanisms in maternal behavior, aggression, and fear memory Cell-type-specific signatures in reward and stress circuits She has no explicitly listed scientific awards in the provided text, but her leadership, high-impact publications, and NIH-level research program indicate significant recognition in the field. Dr. Martinowich advises a diverse team of graduate students, postdocs, and research associates affiliated with programs in Neuroscience, BCMB, CMM, and Human Genetics at Johns Hopkins. Her lab has secured substantial funding to support cross-species studies integrating molecular profiling with behavioral neuroscience. She collaborates extensively with experts in bioinformatics, genomics, and psychiatry. Her laboratory at the Lieber Institute for Brain Development in Baltimore is a hub for translational neuroscience, combining wet-lab experimentation with computational analysis. The team develops interactive dashboards for public data access and focuses on identifying novel therapeutic targets for psychiatric disorders. Current directions include refining spatial transcriptomic methods and reverse-translating human genetic findings into causal animal models.

Karen T. Hastingsمشاهده پروفایل

استاد

• Skin Cancer
• Immunology
• Dermatology
• +۶ مورد دیگر

Karen T. Hastings is a Professor and Inaugural Chair of the Department of Dermatology at the University of Arizona College of Medicine - Phoenix . Her research program focuses on antigen presentation , T cell responses , and neoantigen dynamics in skin cancer (melanoma and cutaneous squamous cell carcinoma). She leads a multidisciplinary team combining immunological , bioinformatic , and molecular biological approaches. Education: MD, PhD (Immunology) - Harvard University (2000) Residency - Yale New Haven Hospital (Dermatology, 2004) Postdoctoral Fellowship - Yale University (Immunobiology, 2006) Research Interests encompass skin cancer immunobiology , antigen processing , immune checkpoint regulation , and bioinformatics modeling of neoantigen landscapes. Her lab has defined GILT as a critical enzyme in MHC class II antigen presentation and investigates its role in tumor-immune interactions using: Genetically engineered mouse models Human tumor specimen analysis Transcriptomic profiling Multi-omics integration Immune cell deconvolution Her scientific contributions include: Elucidating GILT's role in central T cell tolerance Developing neoantigen prediction frameworks Characterizing immune infiltration patterns in viral-mediated HCC Identifying sex-based molecular differences in HCC Trainees under her mentorship have received NIH F30 grants , Medical Student Awards , and travel awards to international conferences. The Hastings Lab collaborates with researchers at Arizona State University and participates in translational cancer research initiatives.

Michal K. Stachowiakمشاهده پروفایل

استاد

• Bioinformatics
• Cell growth, differentiation and development
• Epigenetics
• +۹ مورد دیگر

Dr. Michal K. Stachowiak is a Professor and Director of the Molecular and Structural Neurobiology Program at the University at Buffalo's Jacobs School of Medicine & Biomedical Sciences. He also leads the Gene Therapy Program and Stem Cell SCEF within the Department of Pathology and Anatomical Sciences. His work focuses on genomic regulation during neurodevelopment, schizophrenia pathophysiology, and translational applications of stem cells and optogenetics. Research interests include: bioinformatics applications in neurobiology, epigenetic mechanisms in cell development, gene therapy strategies, and the role of nuclear FGFR1 signaling in neuronal programming. He pioneered cerebral organoid models to study neurodevelopmental disorders and developed optogenomic interfaces merging light-based control with genomic networks. Recent work emphasizes phase-zero clinical platforms using organoid models for disease modeling, and nanotechnology-based approaches for precise stem cell regulation. His interdisciplinary studies bridge molecular biology, engineering, and clinical translation - highlighted by innovations in neuroengineering optical theranostics and systems genome analysis. Key contributions include identifying TNFα's role in schizophrenia-like organoid abnormalities, demonstrating genome architecture's dependence on nuclear FGFR1, and creating optogenetic tools for neuronal network control. His lab's technologies include ORMosil nanoparticles for gene delivery and Vis/NIR spectroscopy-based diagnostic platforms for organoid assays.

Hind J. Fadelمشاهده پروفایل

استادیار

• Virology
• Gene Therapy
• HIV Cure Research
• +۱۲ مورد دیگر

Hind J. Fadel, M.D., Ph.D., is an Assistant Professor of Medicine at Mayo Clinic in Rochester, Minnesota, with a primary appointment as Consultant in the Division of Infectious Diseases, Department of Internal Medicine, and a joint appointment in the Department of Molecular Medicine. Her work bridges clinical practice and translational research in virology and gene therapy. Education: Ph.D. in Virology and Gene Therapy, Mayo Graduate School, Mayo Clinic College of Medicine Residency in Infectious Disease, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine Residency in Internal Medicine, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine M.D., Saint Joseph University, Faculty of Medicine Dr. Fadel’s research focuses on the molecular biology of viral replication, particularly HIV, and the development of genome engineering tools such as CRISPR-Cas and TALENs to create HIV-resistant immune cells and advance cure strategies. Her lab also investigates host-pathogen interactions in emerging viruses like Ebola, influenza, and chikungunya. She employs humanized mouse models and advanced molecular techniques to study viral integration and host factors such as LEDGF/p75. Her work has significant implications for regenerative medicine and cell-mediated immunotherapeutics. The most recent publications reflect a strong trajectory in HIV molecular virology, antiviral mechanisms, and host-pathogen dynamics, with extensions into public health research during the COVID-19 pandemic and co-infection outcomes. Her studies often involve multi-center collaborations and utilize structural, biochemical, and clinical data. Scientific Awards: Young Investigator Award, 21st Conference on Retroviruses and Opportunistic Infections (2014) Young Investigator Award, 19th Conference on Retroviruses and Opportunistic Infections (2012) Division of Infectious Diseases Research Fellows' Award, Mayo Clinic (2011) Award-winning poster, North Central Chapter of IDSA (2010) Dr. Fadel is actively involved in mentoring residents, graduate students, and fellows, and contributes to education in infectious diseases. She is a member of the Infectious Diseases Society of America, Minnesota Medical Association, and the Institutional Biosafety Committee at Mayo Clinic. Her clinical expertise includes ICU infections, care of immunocompromised patients, and outpatient management of HIV/AIDS. Her research is conducted within the interdisciplinary environment of Mayo Clinic, utilizing core facilities in molecular medicine and infectious disease research. She collaborates across departments and institutions, contributing to both basic science and clinical trials infrastructure.

William Murphyمشاهده پروفایل

استاد

• Biomaterials
• Tissue Engineering
• Stem Cell Research
• +۴ مورد دیگر

William Murphy is a Professor in the Department of Biomedical Engineering at the University of Wisconsin-Madison, with affiliated roles in Materials Science & Engineering. His research focuses on creating bioinspired biomaterials, defining stem cell microenvironments, advancing tissue regeneration, and developing novel drug/gene delivery systems. Education PhD (2002) and MS (2000) from University of Michigan BA (1998) from Illinois Wesleyan University Murphy’s work bridges materials science and biomedical applications, emphasizing synthetic hydrogels, mineral-coated substrates, and interdisciplinary approaches to regenerative medicine. His research includes organoid modeling, mRNA therapeutics, and plant-derived scaffolds. Key scientific awards include the Kellett Award (2021), NSF CAREER Award (2008), and fellowships from the Biomedical Engineering Society (2020) and American Institute for Medical and Biological Engineering (2014). He has also received teaching honors like the UW Teaching Academy Award (2005). Murphy’s publications highlight advancements in biomaterials for stem cell culture, spinal cord repair, cardiomyocyte differentiation, and mRNA stabilization. His lab explores both synthetic and plant-based scaffolds, cytokine delivery, and genome editing applications. Grants NIH National Research Service Award (2003) NIH Cellular Biotechnology Predoctoral Fellowship (2000) NSF Research Experience for Undergraduates Fellowship (1997)

• Bacteriophage Therapy
• Antimicrobial Resistance
• Protein Engineering
• +۳ مورد دیگر

Niels Vander Elst is a Postdoctoral Researcher at the Department of Neuroscience, Karolinska Institutet, affiliated with the Neuro-infections & Neuroinflammation research group led by Federico Iovino. He specializes in bacteriophage-derived endolysins as innovative antimicrobials to combat antibiotic-resistant infections, particularly in Gram-positive pathogens such as Streptococcus and Staphylococcus . Dr. Vander Elst holds a dual PhD in Biotechnology and Veterinary Medicine from KU Leuven and Ghent University, funded by the Research Foundation Flanders (FWO), and conducted research at the University of Maryland under a fellowship from the Belgian American Educational Foundation (BAEF). His research focuses on: Bacteriophage therapy and endolysin engineering Antibiotic resistance reversal mechanisms Neuro-infections and blood-brain barrier penetration Veterinary applications of antimicrobials Protein engineering and synthetic biology approaches His publications demonstrate a progression from veterinary applications toward human medical innovations, with recent work focusing on restoring antibiotic susceptibility in resistant pathogens and treating central nervous system infections. Earlier research established foundational work on bovine mastitis therapeutics. Honors include: Finalist for University of Maryland's 'Invention of the Year' (2020) Award recipient at the Encephalitis Meeting in London (2024) Significant grants supporting his work: Kronprinsessan Lovisas Förening (2023, 2025): Endolysins for pneumococcal meningitis treatment Fonds Wetenschappelijk Onderzoek (2020-2023): Engineering endolysins for bovine mastitis Belgian American Educational Foundation (2019): Bacteriophage-endolysin therapy development Beyond research, Dr. Vander Elst teaches neurohistology in KI's medical curriculum, serves in the Junior Faculty Leadership, and promotes open science initiatives. He actively communicates scientific advancements through public outreach articles on phage-based antimicrobials.

• Psychiatric Neuroscience
• Cognitive-Emotional Interactions
• Sleep Research
• +۵ مورد دیگر

Martin Desseilles is a psychiatrist, psychotherapist, and professor at the Faculty of Medicine of the University of Namur in Belgium. His academic appointment is within the Department of Psychology, and he is affiliated with multiple research units including the Clinical Pharmacology and Toxicology Research Unit, Transitions, Namur Institute for Complex Systems, and the Philosophical Space of Namur. He divides his time between clinical practice and research in psychiatric neuroscience, regularly giving courses and lectures both in Belgium and abroad. Dr. Desseilles holds a Doctor of Medicine degree from the University of Liège, granted on June 30, 2009. His research focuses on the interactions of cognitions and emotions through various techniques including behavioral, pharmacological, electrophysiological and neuroimaging approaches. He examines these interactions across different states (wakefulness, sleep, hypnosis and meditation) and in diverse populations (healthy individuals, those with mood disorders, anxiety disorders, and substance overconsumption). His work spans several key areas: psychiatric neuroscience, cognitive-emotional interactions, sleep research, neuroimaging, mood and anxiety disorders, and behavioral neuroscience. Recent publications demonstrate a strong focus on medical student well-being, digital phenotyping in autism, family caregiver assessment, addiction medicine, and innovative approaches to detecting domestic violence. Dr. Desseilles has written or co-written numerous original articles published in internationally recognized medical journals, edited three books, and published numerous book chapters, with a total of 161 research outputs documented. His research fingerprint prominently features sleep (100%), brain (52%), patients (51%), humans (47%), learning (36%), processing (35%), data (30%), and control (28%). Active participant in the McGill Family Medicine Education Research Group (FMER) Speaker at the Belgian College of Neuropsychopharmacology and Biological Psychiatry symposium (2018) Presenter at the French Congress of Psychiatry (2018) Contributor to Messa Belgium and Forum for Medical Education events (2018) His research portfolio includes five major projects, with one currently active (Research in behavioral neuroscience based on mouse models), two finished projects (ETEST and SATRAP), and two not yet started. He has supervised 24 research works and maintains an active presence in both clinical practice and academic research, contributing to mental health initiatives and student well-being programs at the University of Namur.

• Statistical Bioinformatics
• Computational Biology
• Spatial Transcriptomics
• +۴ مورد دیگر

Dr. Shila Ghazanfar is an Australian Research Council DECRA Fellow at the University of Sydney, Faculty of Science. She is an expert in statistical and computational analysis of spatial transcriptomics and single-cell RNA-seq data, with a focus on developing bioinformatic approaches for integrating complex biological datasets across various omics modalities. Her educational background includes: Undergraduate studies in statistics and statistical bioinformatics at The University of Sydney PhD in statistics and statistical bioinformatics at The University of Sydney Royal Society Newton International Fellowship at The University of Cambridge under Dr. John Marioni in computational biology Dr. Ghazanfar's research interests center on developing statistical bioinformatic and biomedical data science approaches for meaningful integration of complex and high-dimensional biological datasets. Her multidisciplinary expertise spans statistics, statistical bioinformatics, and computational biology, enabling her to devise strategies to jointly model processes generating diverse data sources. Her work aligns with the University of Sydney Faculty of Science Research Strengths in Complex Systems, Precision and Digital Health, and Data and Decisions. Analysis of her recent publications (2021-2025) reveals strong focus areas including spatial transcriptomics infrastructure development, single-cell data integration methodologies, and applications in cancer research and cardiovascular biology. Key trends show progression from foundational method development to increasingly sophisticated multi-modal integration approaches, with significant emphasis on creating open-source computational tools for the research community. Her scientific recognition includes: Australian Research Council DECRA Fellowship Royal Society Newton International Fellowship Dr. Ghazanfar actively mentors research students, including Angel GUAN working on melanoma immunotherapy research. Her grant portfolio demonstrates substantial research support: 2023: Statistical Bioinformatics for Single Cell, Spatial and Multiomic Biotechnologies (Faculty of Science) 2022: Defining spatiotemporal mechanisms for peripheral nerve regeneration (Partnership Collaboration Award) 2022: Multiscale data integration for single cell spatial genomics (Chan Zuckerberg Initiative) Australian Research Council DECRA for statistical approaches in spatial genomics As a member of the Charles Perkins Centre, Dr. Ghazanfar participates in interdisciplinary research addressing complex health challenges through computational biology approaches, with collaborations spanning multiple domains from basic science to clinical applications.

Natalie Borgمشاهده پروفایل

دانشیار

• Innate immunity
• Microbial pathogenesis
• Antiviral drug discovery
• +۲ مورد دیگر

Associate Professor Natalie Borg is a faculty member in the Department of Health and Biomedical Sciences at RMIT University , Australia. She leads the Immunity and Immune Evasion Laboratory and holds the title of RMIT Senior Research Translation Fellow . Her research focuses on innate immunity and how pathogens manipulate immune responses. This work drives antimicrobial drug discovery programs and investigates nanostructured surface applications for viral inactivation. Scientific Awards NHMRC Peter Doherty Fellowship NHMRC Career Development Award L'Oreal for Women in Science Fellowship ARC Future Fellowship Her research programs have secured $3.65 million in competitive national funding from ARC, NHMRC, and the US Leukemia and Lymphoma Society, alongside $1.16 million in translational grants supporting multidisciplinary collaborations and a technology licensing agreement.

• Biochemistry
• Bio-energy with carbon capture and storage
• Bioinformatics
• +۵ مورد دیگر

Angela Re is an Associate Professor in the Department of Applied Science and Technology (DISAT) at the Polytechnic University of Turin, specializing in computational biology and bioinformatics with applications spanning sustainable energy, healthcare, and environmental systems. Her research focuses on two primary domains: Data-driven biomolecular space representations through database development and network analysis tools Computational biology applied to prokaryotic/eukaryotic organisms across diverse ecosystems and industrial contexts Her work integrates bioinformatics, biophysics, and medical informatics to address UN Sustainable Development Goals including climate action (13), affordable clean energy (7), and good health (3). Recent publications (2024-2025) reveal strong thematic convergence in microbiome analysis, metabolic engineering, and protein function prediction. Key trends include machine learning applications for genomic data interpretation, sustainable chemical production using engineered microorganisms, and gut microbiota dynamics in neurodegenerative disease models. She actively mentors doctoral researchers and secures competitive funding: Supervised PhD students: Giulia Usai (2020-2024) and Luca Ricci (2019-2023) Current projects: PROT-mBIOMA-AD (Scientific Responsible, 2023-2025) on Alzheimer's gut microbiota, PNRR NEST Spoke 3 (2022-2025) for energy transition, and Solvay contract for battery membrane development Her research operates within the Institute of Fundamental Physics and Materials for Nanotechnology (DISAT), driving computational approaches to sustainable biotechnology challenges.

Hsiao-Tuan Chaoمشاهده پروفایل

استادیار

• Neurodevelopmental disorders
• Autism spectrum disorders
• Epilepsy genetics
• +۷ مورد دیگر

Dr. Hsiao-Tuan Chao is an Assistant Professor at Baylor College of Medicine with primary appointments in the Department of Pediatrics (Division of Neurology and Developmental Neuroscience), Department of Molecular and Human Genetics, and Department of Neuroscience. She serves as an Investigator at the Jan and Dan Duncan Neurological Research Institute and Texas Children's Hospital, and is a McNair Scholar at the McNair Medical Institute. Dr. Chao also holds leadership roles as Associate Program Director for the Basic Neuroscience Pathway in the Child Neurology Residency Training Program and as a Faculty Senator at Baylor College of Medicine. Dr. Chao's educational background includes: MD from Baylor College of Medicine (2012) PhD in Neuroscience from Baylor College of Medicine (2010) BS in Neuroscience and BA in Biochemistry (summa cum laude) from University of Texas at Austin (2002) Plan II Honors in Liberal Arts (summa cum laude) from University of Texas at Austin (2002) Her research focuses on understanding the genetic and neurophysiologic underpinnings of neurodevelopmental disorders including intellectual disability, epilepsy, autism, and schizophrenia. A central theme in her work is examining how disrupted inhibitory neuronal development and function contribute to these conditions. The Chao Lab integrates cross-species approaches using human genomics to uncover genetic etiologies, fruit flies to elucidate molecular pathways, and mice to explore consequences in the mammalian brain. Key research areas include EBF3-related disorders (HADDS syndrome), STXBP1 encephalopathy, EIF2AK variants (LEUDEN and LEMPSAD syndromes), and PPFIA3-related neurodevelopmental disorders. Analysis of Dr. Chao's recent publications reveals a strong focus on identifying novel disease genes and characterizing genotype-phenotype relationships in neurodevelopmental disorders. Her work spans multiple technical approaches including whole-genome sequencing, RNA sequencing, DNA methylation analysis, and functional validation using model organisms. A significant portion of her research examines how specific genetic variants impact protein function and neuronal development, with particular attention to transcriptional regulation, protein translation, and synaptic function. Dr. Chao has received numerous prestigious awards recognizing her contributions to neuroscience and neurology: 2022 "40 Under 40" List of Autism Researchers (Global Rising Stars in Autism Research) 2022 Young Investigator Award from Baylor College of Medicine Department of Pediatrics 2022 Induction to the Society for Pediatric Research 2020 Philip R. Dodge Young Investigator Award from the Child Neurology Society 2019 Health Care Heroes - Rising Star Award from Houston Business Journal 2017 STAT Wunderkind Award Dr. Chao actively mentors a large team of researchers including postdoctoral fellows, graduate students, medical students, and genetic counseling students. Her lab has secured significant funding including an NIH R01 grant (Molecular and Cellular Mechanisms of Cerebellar Dysfunction in Neurodevelopmental disorders), a DP5 Early Independence Award from NIH, and funding from the Burroughs Wellcome Fund. Current research initiatives include the Undiagnosed Epilepsy Genetics Initiative, EBF3-related disorders research study, and a Phase 1/2a clinical trial of CAP-002 Gene Therapy for STXBP1 Encephalopathy. The Chao Lab operates within the Jan and Dan Duncan Neurological Research Institute, leveraging multiple core facilities including the Microscopy Core, Rodent Neurobehavior Core, High Throughput Behavioral Screening Core, and Optogenetics and Viral Vectors Core. Her team collaborates extensively with the Undiagnosed Diseases Network and maintains active partnerships with clinicians at Texas Children's Hospital to translate research findings into clinical applications.

• Neurodegenerative Diseases
• Motor Neuron Biology
• Genetic Disorders
• +۵ مورد دیگر

Dr. James Orengo, Associate Professor at Baylor College of Medicine and Director of the Multi-disciplinary ALS Clinic at Michael E. DeBakey VA Medical Center, focuses his research on motor neuron degeneration in neurodegenerative diseases like Spinocerebellar Ataxia Type 1 (SCA1) and ALS . His lab employs mouse models , transgenic zebrafish lines , and human iNeurons to investigate disease mechanisms. Key research areas include: Pathogenic drivers of bulbar dysfunction in SCA1 Transcriptomics of motor neuron degeneration Cross-species modeling (Human, Mouse, Zebrafish) Collaborations with the Undiagnosed Diseases Network (UDN) Dr. Orengo also contributes to clinical care through the BCM ALS Clinic and co-leads multidisciplinary teams at the Michael E. DeBakey VA Medical Center . His lab develops tools for CRISPRi screens and live imaging in zebrafish to accelerate therapeutic discovery.