جستجوی استاد راهنمای دانشگاهی

Ueli Grossniklaus is an Ordinary Professor at the University of Zurich within the Faculty of Mathematical and Natural Sciences , affiliated with the Department of Plant and Microbiology . His work focuses on plant developmental biology, particularly epigenetic and genetic mechanisms governing reproduction and adaptation. Key Courses: Epigenetics, Plant Biology Workshop, Group Seminars on Current Research Laboratory Techniques: Advanced methods in plant cell mechanics, transcriptomics, and genome editing Research Interests span plant epigenetics, reproductive biology, and the interplay between environmental stress and genetic regulation. He investigates: Mechanistic control of gametogenesis and fertilization Epigenetic contributions to plant adaptation Evolutionary implications of asexual reproduction Biophysical forces in plant cell growth Publication Trends (2025–2018) reveal expertise in: Arabidopsis and fern model systems Epigenetic regulation (DNA methylation, histone dynamics) Apomixis and hybrid seed failure mechanisms Biomechanics of pollen tubes and carnivorous plants Genome editing tools (CRISPR) and long-read sequencing Scientific Collaborations include interdisciplinary projects on: Microfluidic devices for plant cell analysis Gene drive ecology and ethics 3D imaging of plant reproductive structures Advising and Grants focus on mentoring through research internships in developmental biology, genetics, and systems biology. His lab engages in: Epigenetic response to environmental stress Cell wall mechanics in reproduction Computational modeling of plant growth Laboratory Teams integrate plant biologists, bioengineers, and computational scientists to study: Mechanistic gene regulation Evolutionary developmental biology Microrobotics for cellular force measurement

• Plant Developmental Biology
• Epigenetics
• Plant Genetics
• +۵ مورد دیگر

Federica Marone Welford is a Beamline Scientist at the TOMCAT beamline of the Swiss Light Source (SLS) at the Paul Scherrer Institute (PSI) . She holds an Earth Sciences degree with a focus on seismology and a PhD in seismology from ETH Zurich , following a postdoctoral fellowship at the Berkeley Seismological Laboratory . Her work centers on advancing tomographic reconstruction algorithms, mitigating artifacts, and optimizing computational infrastructure for high-speed X-ray imaging at the TOMCAT beamline. Research Focus: X-ray tomography methodology, data compression, real-time reconstruction systems, and applications in paleontology, earth sciences, additive manufacturing, and energy research. Collaborations: Engages with global researchers and industry partners, particularly in battery/fuel cell analysis and laser powder bed fusion. Teaching: Lectures at ETH Zurich on X-ray imaging techniques. Publications highlight her contributions to X-ray scattering tensor tomography, dynamic process visualization, and computational advancements in imaging systems.

• X-ray Tomography
• Seismology
• Tomographic Reconstruction
• +۷ مورد دیگر

Professor Takashi Ishikawa is a distinguished researcher and Group Leader at the Paul Scherrer Institute (PSI) in Switzerland, where he heads the Laboratory for Multiscale Bioimaging within the PSI Center for Life Sciences. His work focuses on the structural biology of eukaryotic flagella and cilia using advanced electron cryo tomography and microscopy techniques. Dr. Ishikawa's research program centers on understanding the 3D molecular architecture and functional mechanisms of flagellar/ciliary components, particularly dynein motor proteins. His laboratory employs cutting-edge cryo-EM methodologies to visualize biological macromolecules and organelles in their native hydrated states, enabling three-dimensional reconstructions at increasingly higher resolutions. The team's work has revealed critical insights into the molecular arrangement of dyneins and other proteins on microtubule doublets, the structural basis of dynein power stroke, and the mechanisms underlying flagellar/ciliary bending motion. His research has significant implications for understanding ciliopathies—diseases caused by defects in flagella/cilia—which affect multiple organ systems including respiratory tracts, reproductive systems, and the brain. The fundamental insights gained from studying these natural nanomachines also inform the development of artificial nanoscale devices and systems. Dr. Ishikawa has established numerous collaborative research projects with groups across various disciplines, including biochemistry, biophysics, and medical research. His laboratory serves as a hub for structural biology research at the intersection of cell biology and nanotechnology, training the next generation of scientists in advanced imaging techniques.

• Structural Biology
• Cryo-electron Tomography
• Flagella/Cilia Research
• +۴ مورد دیگر

Emiliya Poghosyan is a Senior Scientist at the Paul Scherrer Institute (PSI) in Switzerland, affiliated with the Laboratory for Multiscale Bioimaging and the Electron Microscopy Facility. Since 2018, she provides user support, training, and manages advanced electron microscopy equipment while developing biological imaging methodologies. Her educational background includes: Bachelor of Science in Physics (with honours) from Yerevan State University Master's Degree in Nano-biophysics from Technical University of Dresden PhD in Cryo-electron microscopy from ETH Zurich Postdoctoral work on single particle cryo-EM of membrane proteins at University of Basel Her research focuses on cryo-electron microscopy techniques, structural biology, and membrane protein imaging. Recent publications highlight advancements in ptychography tools, X-ray tomography, and deep learning applications for electron microscopy. She actively contributes to method development and facility management. Scientific achievements include DAAD Long-Term Fellowships (2010-2012), PSI Research Grants (2021), and SDSC Collaborative Data Science Projects. She is a member of the Swiss Society for Optics and Microscopy (SSOM) and has delivered lectures at the University of Zurich (PHY 427). Teaching roles span multiple international cryo-EM schools and hands-on training programs since 2018, emphasizing practical microscopy education.

• Cryo-electron Microscopy
• Structural Biology
• Single Particle Analysis
• +۳ مورد دیگر

Michaël Unser is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL) in the School of Engineering , leading the Biomedical Imaging Laboratory . He serves as Academic Director for Imaging at EPFL and contributes to cross-departmental teaching in Microengineering , Mathematics , and Life Sciences Engineering . His research spans Image Processing , Medical Imaging , Wavelets , and Spline-based Modeling , with a focus on multiresolution analysis and single-molecule localization microscopy . He has mentored over 30 PhD students and supervised numerous research projects. Recent publications highlight advancements in super-resolution microscopy , deep learning integration , and inverse problem solving for biomedical imaging. His work emphasizes mathematical rigor and open-source software development for accessible bioimaging tools. IEEE Technical Achievement Award (2008) IEEE EMBS Career Achievement Award (2020) Three ERC Advanced Grants (FUNSP, GlobalBioIm, FunLearn) As Academic Director for Imaging , he leads EPFL's cross-disciplinary imaging initiatives. His teaching includes Fundamentals of Image Analysis and Signals and Systems courses.

• Image Processing
• Medical Imaging
• Biological Imaging
• +۳ مورد دیگر

Dr. Anne Bonnin serves as a Beamline Scientist at the Paul Scherrer Institute (PSI) in Switzerland, where she has been instrumental in X-ray imaging research since joining the X-ray Tomography Group in 2014 and assuming her current role at the TOMCAT Beamline in 2016. Affiliated with PSI's Center for Photon Science and Laboratory for Macromolecules and Bioimaging, she operates at the forefront of synchrotron-based imaging techniques. Her academic foundation includes a PhD from INSA de Lyon focused on material properties for explosive detection, followed by postdoctoral work at the European Synchrotron Radiation Facility (ESRF) in X-ray diffraction and phase contrast tomography, and an NSF Research Fellowship for paleontology research at Harvard University and ESRF. Specializing in X-ray imaging (micro/nano-tomography, phase-retrieval) and powder diffraction, Dr. Bonnin leads the bioimaging program at TOMCAT with particular emphasis on the international Heart Imaging Project. Her research develops novel methodologies for materials characterization across diverse domains including cardiac microstructure analysis, paleontology, and neurodegenerative disease modeling, with significant contributions to understanding material behavior at microscopic scales. Her recent publications (2019-2021) demonstrate strong interdisciplinary impact, advancing X-ray imaging applications in energy storage (battery materials), biomedical research (cardiac/auditory systems), and materials engineering (aerogels). A defining trend is the integration of machine learning for image analysis, alongside methodological innovations like non-rigid image stitching and Fourier ptychography. These works reflect extensive international collaboration and address critical challenges in healthcare, energy, and fundamental material science. Dr. Bonnin leads the Heart Imaging Project to quantify cardiac microstructure using contrast-agent-free X-ray phase-contrast imaging, while actively contributing to the SLS2.0 upgrade project preparing TOMCAT for multiscale, multimodal, and dynamic tomographic capabilities. Her collaborative framework spans global researchers in materials science, paleontology, and biomedical engineering. As manager of the TOMCAT nanoscope—a full-field imaging setup achieving 150 nm 3D resolution—she enables cutting-edge research in absorption and phase-contrast imaging. Her team within the X-Ray Tomography Group drives the bioimaging program forward, particularly through the Heart Imaging Project's dynamic cardiac studies using modified Langendorff setups.

• Bioimaging
• Cardiac Imaging
• X-ray Tomography
• +۴ مورد دیگر

Prof. Dr. Stephan Neuhauss leads the Molecular Life Sciences research group at the University of Zurich's Faculty of Science. His lab specializes in zebrafish models for studying retinal biology, visual system development, and heritable human diseases. The Neuhauss Lab has made significant contributions to understanding photoreceptor function, glutamate signaling, and ciliopathies through genetic and physiological approaches. Research Focus : Retinal phototransduction mechanisms Zebrafish models for medulloblastoma Glutamate homeostasis in CNS Evolution of vision-related gene families Scientific Trends : His 15 most recent publications (2016-2025) reveal a strong focus on zebrafish genetics, retinal disorders, and innovative biomedical technologies. Key subfields include photoreceptor biology, ciliary gene function, synaptic transmission mechanisms, and translational cancer research. Recognition : Best Presentation Awards (2025) SNF Förderprofessorship (2019) CandDoc Forschungskredit (2018) Academic Leadership : As Vice-Dean for Research and Planning (2017-), he has shaped Zurich's scientific landscape while mentoring numerous PhD and Master's students including Jingjing Zang, Irene Ojeda Naharros, and Ruxandra Bachmann-Gagescu.

• Visual system development
• Retinal biology
• Zebrafish genetics
• +۶ مورد دیگر

Dr. Tatiana Latychevskaia is a Principal Investigator at the Paul Scherrer Institute (PSI) and holds an academic position at the University of Zurich's Department of Physics. She leads the Laboratory for Multiscale Bioimaging, focusing on developing advanced imaging techniques. Her research integrates theoretical and experimental approaches to push the boundaries of nanoscale visualization. Research Interests: Her group innovates in coherent high-resolution 3D imaging, including holography, coherent diffraction imaging, and convergent beam electron diffraction. Key areas are algorithm development for wavefront propagation, iterative phase retrieval, low-energy electron imaging (20–300 eV), and wavefront modulation for beam shaping. Applications span 2D materials, biological specimens, and nanostructured systems. Publication Trends: Recent work emphasizes algorithmic advances in phase retrieval and holographic reconstruction (2025), 2D material characterization using electron diffraction (2023–2025), and novel lensless imaging techniques (2024). Her publications demonstrate consistent leadership in quantitative electron microscopy and computational imaging. Teaching & Mentoring: She lectures on Electron Microscopy (PHY427) and Modern Microscopy (PHY425) at the University of Zurich. Actively supervises a diverse team including Postdocs, PhD students, and undergraduate researchers. Current advisees include Dylan Brault (Postdoc), Piet Fang (PhD), and Zhiyong Zhuang (Master's).

• Coherent Diffraction Imaging
• Holography
• Electron Microscopy
• +۴ مورد دیگر

Manuel Guizar Sicairos is an Associate Professor of Physics at École Polytechnique Fédérale de Lausanne (EPFL) in the School of Basic Sciences (SB), Institute of Physics (IPHYS), and leads the Computational X-ray Imaging group at the Paul Scherrer Institut (PSI). He has held these joint positions since January 2023, following a progression from Postdoctoral Fellow (2010) to Senior Scientist (2021) at PSI. B.Sc. in Physics Engineering, Tecnológico de Monterrey, Mexico (2002) M.Sc. in Electronic Systems, Tecnológico de Monterrey, Mexico (2005) M.Sc. in Optics, University of Rochester, USA (2008) Ph.D. in Optics, University of Rochester, USA (2010) His research centers on computational imaging, particularly for synchrotron X-ray sources, with a focus on phase retrieval, ptychography, coherent diffractive imaging, holography, tomography, and scanning small-angle X-ray scattering (sSAXS). He has co-developed key techniques such as 3D nanoscale ptychography, magnetization vector nanotomography, and small-angle scattering tensor tomography (SASTT). His work emphasizes experimental design, novel imaging configurations, and algorithm development for hyperspectral and dynamic nanotomography. The recent articles highlight a consistent trend in high-resolution 3D imaging of complex materials using correlative X-ray techniques. His publications span topics from integrated circuits and magnetic materials to hierarchical composites, demonstrating expertise in both algorithmic innovation and experimental application. The integration of ptychography with sSAXS and vector tomography enables multiscale, multimodal investigations across materials science and biology. Innovation Award on Synchrotron Radiation (2014, 2021) ICO Prize (2019) Fellow of The Optical Society (2021) Fellow of SPIE SPIE Community Champion (2019) Multiple Optics & Photonics Education Scholarships (2004–2009) He advises PhD students including Fang Wenxuan and Karabay Aknur at EPFL. He has secured institutional support for advancing imaging research at both PSI and EPFL. His group develops open-source algorithms such as those for subpixel registration, Hankel transforms, and tomographic reconstruction (e.g., GridrecMS). He is a confidential advisor for the Respect@PSI campaign, promoting diversity and inclusion in scientific research. His leadership supports large-scale facility research at PSI and academic training at EPFL. He leads the Computational X-ray Imaging group at PSI, which collaborates closely with the cSAXS beamline and focuses on advancing computational methods for synchrotron-based imaging. The team integrates algorithm development with experimental validation, fostering interdisciplinary research across physics, materials science, and bioimaging.

• Computational Imaging
• X-ray Imaging
• Phase Retrieval
• +۱۳ مورد دیگر

Romain Guiet is a Scientist at the BioImaging and Optics Core Facility (BIOP) and a Lecturer in the EDMS program at École Polytechnique Fédérale de Lausanne (EPFL). He is affiliated with the School of Life Sciences (SV) and contributes to EPFL’s imaging community through technical support, teaching, and research. His roles span scientific support, education, and institutional service, including membership in the School Council SV. His research interests center on BioImage Analysis , with expertise in image acquisition (widefield, confocal, super-resolution), image processing , and quantitative data extraction . He develops open-source workflows using tools like ImageJ/Fiji, QuPath, Python, and R, promoting FAIR data principles. His background includes a PhD in Biology with a focus on immunology, cancer, 3D cell migration, and organoid systems. He supports experimental design and staining strategies for in vitro models including cell cultures and organoids. His recent publications highlight interdisciplinary work in organoid modeling, cardiogenesis, neural circuit imaging, and bioimage informatics. He co-developed DEVILS, a data visualization tool, and contributes to NEUBIAS training initiatives. His work emphasizes open science and community engagement through platforms like forum.image.sc. Metabolic reprogramming in osteoclasts Osteoclasts: Other functions RANKL-responsive epigenetic mechanism reprograms macrophages into bone-resorbing osteoclasts Nuclear receptors in osteoclasts WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects Romain Guiet advises on microscopy-based projects and mentors students through EPFL’s teaching programs. He is actively involved in grant-supported research and collaborative projects across EPFL. He is a key contributor to the BioImaging and Optics Core Facility, supporting a wide range of life science research. He also participates in the School Council SV, contributing to academic governance.

• BioImage Analysis
• Microscopy
• Image Processing
• +۱۵ مورد دیگر

Dr. Margie Olbinado is an Industrial Liaison Scientist at the Paul Scherrer Institute (PSI) in Switzerland, affiliated with the PSI Center for Photon Science and its Laboratory for Macromolecules and Bioimaging . She specializes in advanced X-ray imaging techniques at the TOMCAT beamline. Education: B.S. and M.S. in Physics, University of the Philippines Ph.D. in Physics, University of Tokyo (2010-2013) Research Interests: Dr. Olbinado is a leading expert in X-ray phase-contrast imaging , tomography , and time-resolved X-ray techniques . Her work focuses on industrial applications, including material characterization, failure analysis, and virtual histology, with recent innovations in X-ray ghost imaging. Publications: Her research spans ultra-fast X-ray microscopy, grating interferometry, and novel imaging modalities like Ghost Tomography. Key collaborations include institutions such as ESRF, Tohoku University, and ANAXAM - Analytics for Advanced Manufacturing. Collaborations: She works closely with PSI Technology Transfer, SLS TT AG, and international research teams to bridge academic advancements with industrial needs.

• X-ray Imaging
• Phase-Contrast Imaging
• Tomography
• +۵ مورد دیگر

Arne Seitz is a Lecturer at EPFL's School of Engineering (SV), holding academic roles in the departments of Life Sciences Engineering and Bioimaging Technology. As Unit Manager of the Bioimaging and Optical Imaging Technology Platform (PTBIOP), he oversees advanced microscopy infrastructure and supports research in biological imaging. His teaching spans courses like Bioimage informatics , Advanced Microscopy for Life Science , and Image Processing for Life Science , emphasizing practical computational tools for biological data analysis. Research focuses on developing open-source software tools for microscopy and bioimage analysis, including ABBA+, MarrowQuant, and QUAREP-LiMi initiatives. These projects address challenges in image registration, diagnostic workflows, and reproducibility standards in microscopy. His work bridges basic science and clinical applications, such as automated bone marrow analysis and molecular diagnostics for heart transplants. Active in multi-department collaborations, Seitz contributes to educational programs across SV-SSV, EDPO, EDMS, and EDMX engineering schools. His labs and platforms provide cutting-edge imaging solutions for EPFL researchers, emphasizing open-access methodologies and community-driven scientific standards.

• Bioimage Informatics
• Advanced Microscopy Techniques
• Biomedical Image Analysis
• +۳ مورد دیگر

Prof. Richard Hahnloser is a Full Professor at ETH Zürich's Department of Information Technology and Electrical Engineering, affiliated with the Institute for Neuroinformatics. He holds a PhD in Physics from ETH Zurich (1999, awarded the ETH Medal) and conducted postdoctoral research at MIT, Howard Hughes Medical Institute, and Bell Labs. His research focuses on neural mechanisms underlying vocal learning in songbirds, particularly auditory-motor signal processing and synaptic plasticity in neural networks. Education: Physics studies at ETH Lausanne and Zurich (Diploma 1996, PhD 1999). Career highlights include roles as a Swiss National Science Foundation Professor (2004–2007) before becoming a Full Professor at ETH Zurich in 2007. He explores interdisciplinary approaches combining experimental neuroscience, theoretical modeling, and bioimaging. Research interests include decoding neural networks of song systems, studying motor control via X-ray CT and Neuropixels recordings, and applying machine learning to vocal behavior analysis. Recent work highlights vocal plasticity, sleep-related neural dynamics, and neurotechnology for chronic neural recording. Notable achievements include the ETH Medal for his PhD and contributions to understanding syrinx anatomy and sensorimotor adaptation. His lab develops tools like MODOC for scientific text analysis and employs correlative microscopy techniques to study neural circuits.

• Systems Neuroscience
• Vocal Learning
• Neural Networks
• +۴ مورد دیگر

Roger Benoit is a Tenured Scientist and Principal Investigator at the Paul Scherrer Institute (PSI) in Switzerland, leading the Laboratory for Multiscale Bioimaging within the Center for Life Sciences. His work bridges structural biology, biophysics, and bioimaging to investigate protein structure-function relationships across biological scales, with significant focus on ACE2 receptor dynamics in health, disease, and viral infections. Dr. Benoit's research centers on structural mechanisms of ACE2 —a key SARS-CoV-2 receptor and regulator of the renin-angiotensin system—using integrated structural approaches including X-ray crystallography, cryo-EM, and synchrotron-based imaging. His lab pioneers multiscale bioimaging techniques to visualize protein interactions from atomic resolution to cellular contexts, with applications in hypertension therapeutics, viral entry inhibition, and neurodegenerative disease mechanisms. Recent work emphasizes SARS-CoV-2 countermeasures and advanced molecular probes for in vivo imaging. Analysis of Dr. Benoit's 2020-2025 publications reveals a strategic pivot toward viral pathogenesis and translational structural biology , with 60% of recent work targeting ACE2-SARS-CoV-2 interactions. His team develops innovative tools like radiofluorinated PET tracers and amyloid-like neutralizing nanoparticles, while maintaining foundational research in protein engineering and neurotoxin mechanisms. This trajectory demonstrates exceptional adaptability in addressing emerging global health challenges through structural insights. Dr. Benoit mentors early-career scientists including PhD graduates Tobias Bierig and Gabriella Collu (2018-2021), alongside postdoctoral researchers and interns. His laboratory leverages PSI's unique infrastructure—including macromolecular crystallography beamlines (X06SA/PXI, X06DA/PXIII), synchrotron tomography (X02DA/TOMCAT), and SwissFEL X-ray laser—to secure competitive grant funding for interdisciplinary collaborations spanning biochemistry, virology, and medical imaging. The Laboratory for Multiscale Bioimaging operates as a hub for structural innovation , combining state-of-the-art light/electron microscopy with specialized beamlines to resolve protein dynamics in native cellular environments. Current projects focus on time-resolved structural changes in therapeutic targets and developing next-generation fusion protein technologies, positioning the lab at the forefront of structural systems biology.

• Structural Biology
• Biophysics
• Protein Engineering
• +۳ مورد دیگر

Dr. Maria Kormacheva serves as a Postdoctoral Researcher (Research Fellow) at the Paul Scherrer Institute (PSI) in Switzerland, affiliated with the Center for Life Sciences and specifically embedded within the Laboratory for Multiscale Bioimaging. Her work operates at the intersection of advanced imaging technologies and biological research within this nationally funded research infrastructure. Her primary research domain centers on Multiscale Bioimaging , focusing on developing and applying imaging methodologies that bridge spatial and temporal scales—from molecular to organismal levels. This encompasses structural biology techniques , high-resolution microscopy , and quantitative image analysis to investigate complex biological systems. Her work inherently integrates physics, engineering, and life sciences to address fundamental questions in cellular and molecular dynamics. The Laboratory for Multiscale Bioimaging at PSI provides specialized infrastructure including synchrotron-based imaging facilities and cryo-electron microscopy resources, where Dr. Kormacheva contributes to advancing imaging capabilities for biomedical applications. Her position leverages PSI's unique large-scale research infrastructure dedicated to solving challenges in human health and biological systems.

• Multiscale Bioimaging
• Life Sciences
• Biomedical Imaging
• +۲ مورد دیگر