جست‌وجوی استاد و پژوهشگر

Xi Chenمشاهده پروفایل

استاد

• Carbohydrate Chemistry
• Glycobiology
• Enzymology
• +۷ مورد دیگر

Dr. Xi Chen is a Professor in the Department of Chemistry at the University of California, Davis, where he has been a faculty member since 2003. His research spans carbohydrate chemistry, glycobiology, and cancer biology, with notable contributions to chemoenzymatic methods for glycoconjugate synthesis. Dr. Chen's work focuses on developing hybrid chemical-enzymatic approaches to synthesize complex carbohydrates and glycoconjugates, characterizing glycosyltransferase mechanisms, and designing enzyme mutants for improved catalysis. He also investigates carbohydrate-based diagnostics and therapeutics, particularly in cancer and inflammatory diseases. His recent publications highlight interdisciplinary studies linking carbohydrate metabolism to p53 tumor suppression pathways and RNA-binding protein regulation in cancer. Awards include AAAS Fellow (2015), ACS Isbell Award (2012), and NSF CAREER Award (2006). He earned his Ph.D. at Wayne State University (2000) and B.S. at Xiamen University (1994). Scientific Awards American Association for the Advancement of Science Fellow (2015) Dean's Team Award for Excellence (2013) Carbohydrate Research Award for Creativity (2013) ACS CARB Horace S. Isbell Award (2012)

• Glycoengineering
• Biomaterials
• Biotechnology
• +۳ مورد دیگر

Prof. Dr. rer. nat. Lothar Elling is a University Professor and director at the Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Germany. His research focuses on biomaterials, glycoengineering, and enzymatic synthesis of carbohydrates and glycoconjugates. Institution: RWTH Aachen University Research Unit: Helmholtz Institute for Biomedical Engineering Academic Rank: Full Professor Prof. Elling's research interests include: Glycoengineering of biomaterials Enzymatic synthesis of glycans Glycosyltransferase immobilization Glycan-protein interactions Biocatalytic cascade reactions Biomedical applications of glycomaterials His recent publications demonstrate strong expertise in: - Automated enzymatic glycan synthesis - Multi-enzyme cascade systems for nucleotide sugar production - Glycosyltransferase engineering - Galectin-targeted glycomaterials - Microgel-based biosensors

Susan Brooksمشاهده پروفایل

استاد

• Cancer Biology
• Glycobiology
• Cell Signaling
• +۴ مورد دیگر

Professor Susan Brooks is a faculty member at Oxford Brookes University in the School of Biological and Medical Sciences . Her research focuses on glycobiology , cancer progression , and the role of extracellular vesicles in metastasis. Professor of Cell Biology Director of Researcher Development Focus on breast and ovarian cancer Specialized in glycosylation mechanisms Research Interests : Dr. Brooks' work explores how aberrant glycosylation of proteins and glycans influences cancer cell behavior, including metastasis and drug resistance . Her recent studies examine extracellular vesicles as diagnostic tools and therapeutic targets. Article Trends : Over 25 years, Dr. Brooks has published 15+ articles on glycosylation patterns in breast and ovarian cancer. Key areas include lectin binding , miRNA regulation , and radiation-induced metastatic changes . Her work bridges cell biology and clinical applications .

• Biotechnology
• Systems Engineering in Bioprocessing
• Model-Based Tools
• +۴ مورد دیگر

Professor Cleo Kontoravdi is a Professor of Biological Systems Engineering at the Department of Chemical Engineering, Imperial College London, within the Faculty of Engineering. Her roles include Director of Postgraduate Studies (2021–present) and Postgraduate Admissions Tutor (2018–2021). She holds affiliations with key research centers such as the Centre for Process Systems Engineering, Centre for Synthetic Biology, and Future Vaccine Manufacturing Research Hub. Her research focuses on applying systems engineering principles to bioprocessing, integrating model-based tools like sensitivity analysis and optimization with experimental work on mammalian cell cultures and vaccine production. Key areas include metabolic flux analysis, media optimization, and multiscale modeling. Her recent publications highlight advancements in hybrid modeling frameworks, mRNA vaccine process design, and metabolic engineering of CHO cells. She actively contributes to vaccine manufacturing strategies and sustainable biopharmaceutical supply chains. Education: PhD (2007) and MEng (2002) in Chemical Engineering from Imperial College London. Professional experience spans academic roles (since 2007) and industry R&D at Lonza Biologics (2006–2007). Her work bridges computational biology, bioprocess engineering, and systems biology, addressing challenges in vaccine development and production efficiency. Awards: Not explicitly listed in the provided text. Research grants and collaborations are implied through her involvement in high-impact projects like the Future Vaccine Manufacturing Hub. She advises on bioprocess optimization, glycoengineering, and biomanufacturing sustainability.

• T cell immunology
• Immune tolerance
• Checkpoint inhibitor immunotherapy
• +۵ مورد دیگر

Martina Damo serves as Assistant Professor in the Department of Medicine, Section of Rheumatology at the University of Chicago School of Medicine, where she joined the faculty in October 2023. She leads a research laboratory investigating immune checkpoint receptors on T cells and their role in immunological tolerance, with particular focus on how checkpoint blockade immunotherapy causes immune-related adverse events (irAEs) in cancer patients. Her work aims to identify druggable tolerance pathways and develop bioengineered therapies for tolerance modulation. Dr. Damo's educational background includes: PhD in Bioengineering from Swiss Federal Institute of Technology in Lausanne (EPFL), 2016 Postdoctoral Fellowship in Immunobiology at Yale University, 2022 Instructor position at Yale University, 2023 Her research centers on T cell immunology in physiological and pathological contexts, with emphasis on peripheral tissue immunity. She investigates mechanisms of immune tolerance in skin and liver environments, neoantigen recognition by T cells, and the pathogenesis of irAEs following cancer immunotherapy. Her laboratory employs advanced techniques including clonal lineage tracing, mouse models of cancer and autoimmunity, and bioengineering approaches for therapeutic development. Analysis of her publication history (2011-2025) reveals an evolving research trajectory from foundational work in antigen-specific tolerance and gene therapy (2011-2015) to contemporary focus on T cell exhaustion, checkpoint biology, and cancer immunotherapy applications (2018-2025). Her most cited works involve CD8+ T cell dynamics in tumors and viral infections, with consistent emphasis on translational applications. Key thematic areas include T cell tolerance mechanisms, irAE pathogenesis, and bioengineered tolerance-inducing therapeutics. Dr. Damo actively mentors within her research laboratory and collaborates extensively with immunology researchers including Jeffrey Hubbell, Thomas Gajewski, and Melody Swartz. Her work has attracted significant attention with multiple publications exceeding 100 citations, substantial social media engagement (over 250 X posts), and patent references (23 patents citing her work). She maintains active research funding supporting her laboratory's investigations into T cell tolerance pathways. Her laboratory operates within the University of Chicago's immunology research ecosystem, collaborating with colleagues in the Department of Medicine including Maria-Luisa Alegre and James Curran. Current projects focus on developing targeted approaches to prevent irAEs while preserving anti-tumor efficacy of checkpoint inhibitors, leveraging her expertise in tissue-specific immune regulation.

Ronit Freemanمشاهده پروفایل

دانشیار

• Extracellular Matrix (ECM) Biology
• Synthetic Biology
• Supramolecular Chemistry
• +۷ مورد دیگر

Ronit Freeman, PhD is an Associate Professor in the Department of Applied Physical Sciences at the University of North Carolina at Chapel Hill , where she is also affiliated with the UNC Lineberger Comprehensive Cancer Center . Research Focus : Cellular response to extracellular matrix (ECM) cues across multiple length/time scales Methodologies : Synthetic biology, supramolecular chemistry, DNA/RNA aptamer technology Dr. Freeman's work develops reconfigurable ECM platforms to study and engineer cellular fate decisions through: Controllable biochemical and biomechanical signaling Advanced fibrous architecture design Dynamic topography and mechanics modulation Applications in cancer therapy, wound healing, and fibrosis reversal Key collaborations include: Shawn Hingtgen's lab - Therapeutic cell engineering RNA Discovery Center (led by Chad Pecot) Scientific Achievements: Recipient of Eshelman Institute for Innovation Award (2020) Gordon & Betty Moore Foundation Collaborative Innovation Award (2019) Scialog Fellow (2019) Multiple early-career fellowships (EMBO, Clore, Converging Technologies) Her interdisciplinary team combines expertise from chemistry, cell biology, synthetic biology, medicine, engineering, and physics to address cutting-edge bio-nanotechnology challenges.

• Bioengineering
• Systems Glycobiology
• Thrombosis & Hemostasis
• +۳ مورد دیگر

Sriram Neelamegham is the UB Distinguished Professor of Chemical & Biological Engineering, Biomedical Engineering, and Medicine at the University at Buffalo, SUNY. His research focuses on applying engineering principles to study molecular mechanisms of blood cell interactions in diseases such as inflammation, thrombosis, and cancer. He leads the Bioengineering Laboratory within the School of Engineering and Applied Sciences. Education: PhD in Chemical/Biomedical Engineering, Rice University, 1996 B.Tech in Chemical Engineering, Indian Institute of Technology Delhi, 1991 Research Interests: Systems Glycobiology: Investigating glycan biosynthesis and its role in disease Leukocyte and Platelet Adhesion Dynamics under Fluid Flow Von Willebrand Factor (VWF) Structure-Function Relationships Engineering Glycoengineered Therapeutics and Diagnostic Tools Key Contributions: Developed computational models and experimental tools for glycosylation pathway analysis Discovered mechanisms of VWF conformational changes under shear stress Pioneered glycoengineering strategies for stem cell targeting Awards & Recognition: NIH Independent Scientist Award (2015) SUNY Chancellor's Award for Excellence (2015) AIMBE Fellow (2012) and BMES Fellow (2019) 2018 Schoellkopf Medal (ACS) Lab Activities: Recruitment of postdocs, full-time, and part-time research technicians Development of glycan-engineered technologies for drug delivery and diagnostics Collaborations with biomedical industries and academic institutions

• Glycobiology
• Enzymology
• Synthetic Biology
• +۴ مورد دیگر

Warren Wakarchuk is a Professor in the Biological Sciences Department at the University of Alberta's Faculty of Science. His research focuses on enzymology of glycoconjugates, synthetic biology applications for glycobiology, and bacterial protein glycosylation. He investigates enzymes involved in creating glycan mimics in pathogens and their therapeutic applications, including designer enzymes and synthetic operons for biosynthetic pathways. His lab also explores O-mannosylation in bacteria and its evolutionary conservation. Teaching: He instructs BIOL 514 (Advanced Molecular and Cellular Biology), focusing on scientific writing, data visualization, and peer review for graduate students. This course emphasizes practical skills for thesis research dissemination. Research Trends: Recent articles highlight advancements in O-glycosylation engineering for antibodies, polysialic acid modulation, and lipid nanoparticle delivery systems. His work bridges fundamental glycobiology with applied biotechnology, addressing both mechanistic questions (e.g., clathrin-mediated endocytosis regulation via O-GlcNAc) and translational goals (e.g., therapeutic glycoprotein design). Lab Activities: The Wakarchuk lab uses glycoproteomics and synthetic biology tools to study protein glycosylation mechanisms. Current projects include characterizing novel glycosyltransferases, optimizing enzyme activity through screening platforms, and developing bacterial expression systems for complex glycans.

Scott Wilsonمشاهده پروفایل

استادیار

• Biomaterials
• Immunoengineering
• Drug Delivery
• +۴ مورد دیگر

Scott Wilson, PhD, is an Assistant Professor in the Department of Biomedical Engineering at Johns Hopkins University, affiliated with the Translational Tissue Engineering Center. His research focuses on synthesizing immunomodulatory biomaterials to control adaptive immune responses for treating malignancies, infectious diseases, and autoimmune conditions. Key interests include tolerance-inducing therapies, spatial-temporal drug delivery, and nanoparticle formulations. Education: PhD in Chemical Engineering (Bioengineering) from Georgia Institute of Technology (2011) MS in Chemical Engineering from University of Oklahoma (2004) BS in Chemical Engineering from University of Oklahoma (2001) Research Interests: Wilson’s lab develops bespoke biomaterials to bias immune responses toward immunity or tolerance. Projects include cancer immunotherapy via polymeric glyco-adjuvants, allergy suppression through glycoengineered antigens, and antimicrobial coatings for titanium implants. His work bridges organic chemistry and biomedical applications, emphasizing preclinical validation. Collaborative Grants: Wilson contributed to two Johns Hopkins Discovery Awards (2020 and 2024), fostering interdisciplinary projects. His lab collaborates on translational efforts, including gene therapy delivery systems and osseointegration enhancements. Labs & Teams: The Wilson Laboratory for Biomaterials Synthesis and Immunoengineering focuses on engineering immune responses via functional biomaterials. Key themes include antigen-specific tolerance induction and targeted drug delivery platforms.

Chantelle Capicciottiمشاهده پروفایل

استادیار

• Glycobiology
• Chemical Biology
• Organic Chemistry
• +۳ مورد دیگر

Dr. Chantelle Capicciotti is an Assistant Professor and Queen’s National Scholar in Precision Molecular Medicine at Queen’s University. She holds joint appointments in the Departments of Chemistry and Biomedical and Molecular Sciences (Faculty of Arts and Science), and Surgery (Faculty of Health Sciences). Her research focuses on glycobiology, particularly glycan-protein interactions and glycan-based approaches for biomarkers, diagnostics, and therapies. Education: Ph.D. in Chemistry (2014, University of Ottawa) under Prof. Robert Ben; Postdoc with Prof. Geert-Jan Boons at the University of Georgia’s Complex Carbohydrate Research Center (2014–2018). Research Interests : Elucidating glycan roles in health/disease, developing glycan engineering tools, and advancing glycan-based biomedical applications. Key areas include cell surface glyco-engineering, chemoenzymatic glycan synthesis, and glycan-protein interaction studies. Research Trends in Articles : Recent work emphasizes photoaffinity labeling, exo-enzymatic glycan modification, and synthetic approaches to complex glycans. Themes include cell surface engineering, glycan-functionalized probes, and anti-viral strategies leveraging glycans. Grants & Advising : Mentors graduate/undergraduate students in interdisciplinary glycobiology projects. Active in training programs spanning chemistry, biochemistry, and medical sciences. Labs/Teams : Leads the Chemical Glycobiology Lab at Queen’s, focusing on synthetic and biological glycans. Collaborates with cross-disciplinary groups in precision medicine and molecular engineering.

• Plant Biotechnology
• Molecular Biology
• Biochemistry
• +۴ مورد دیگر

Dr. Alexandra Machado Ferreira Castilho is a leading researcher at the Institute of Plant Biotechnology and Cell Biology within the University of Natural Resources and Life Sciences, Vienna (BOKU) . She has served as Principal Investigator since 2018 and previously as Scientific Coordinator of the Laura Bassi Center PlantBioP (2010-2017). Her work focuses on Plant Molecular Farming and Glycoengineering , aiming to optimize plant-based production of therapeutically relevant glycoproteins. Specializes in tailoring N-glycan profiles for biopharmaceuticals Develops plant cell factories for antibody and decoy receptor production Key projects include SARS-CoV-2 neutralization strategies and cancer immunotherapy agents Her recent publications analyze glycoengineering techniques in Nicotiana benthamiana , covering topics like ACE2-Fc decoys for viral neutralization, PD1/PDL1 blockade for oncology, and protease suppression for protein stability. She has received funding from the Austrian Science Fund (FWF) for projects on immune checkpoint inhibitors and glycosylation pathway modulation.

Danielle Dubeمشاهده پروفایل

استاد

• Chemical Biology
• Glycobiology
• Antibiotic Resistance
• +۳ مورد دیگر

Danielle Dube is the Norma L. and Roland G. Ware, Jr. Professor of Chemistry and Biochemistry and Chair of the Chemistry Department at Bowdoin College. A chemical biologist by training, she received her PhD from UC Berkeley and completed postdoctoral work at Stanford University. Her research focuses on bacterial surface glycans linked to pathogenesis, particularly in Helicobacter pylori , where she develops chemical tools to study and disrupt glycan-mediated interactions. Education : Cornell University (AB in Biology), UC Berkeley (PhD in Chemistry), Stanford University (Postdoctoral) Teaching : Biochemistry, Chemical Biology, General Chemistry, Drug Discovery courses Research Highlights : Structural characterization of H. pylori glycans Development of metabolic inhibitors for glycan biosynthesis Creation of imaging probes for bacterial glycocalyx Immune recognition enhancement through glycan modification Antibiotic hypersensitization via glycan disruption Scientific Recognition : 2022: Recognized in Nobel Prize awarded research by Prof. Carolyn Bertozzi 2018: Recipient of external grant for women scientists 2014: Collaborator on $18.4M INBRE grant Lab & Collaborations : Leads the Dube Research Laboratory at Bowdoin, specializing in chemical approaches to bacterial glycobiology. Collaborates with biochemistry and microbiology teams on antibiotic resistance solutions.

Marc Carnicer Herasمشاهده پروفایل

استادیار

• Metabolic Engineering
• Bioprocess Development
• Microbial Physiology
• +۳ مورد دیگر

Marc Carnicer Heras is an Assistant Professor at the Bioengineering Department of the IQS School of Engineering, Ramon Llull University. His research focuses on metabolic engineering, bioprocess development, and microbial physiology with applications in industrial biotechnology and sustainable production of high-value compounds. He leads or collaborates in multiple research projects, including CROPSAFE (environmentally-friendly agriculture), GLYCOENGIN (glycoenzyme engineering), and paCOSVALOR (chitosan oligosaccharide production). His work integrates genomic analysis, metabolic pathway optimization, and bioprocess scale-up strategies. Recent research highlights include developing genetic tools for chloroplast engineering in microalgae, optimizing vitamin B12 production in Propionibacterium freudenreichii, and analyzing metabolic landscapes of methylotrophic bacteria. His contributions span synthetic biology, bioreactor design, and systems biology approaches to improve industrial microbial strains. Grants/Projects : CROPSAFE (EU), GLYCOENGIN (2023-2026), paCOSVALOR (2022-2024) Key Research Themes : Industrial strain engineering, metabolomics, continuous bioprocess systems

Nikolaos Lourosمشاهده پروفایل

استادیار

• Protein Misfolding and Aggregation
• Amyloid Formation
• Neurodegenerative Diseases
• +۷ مورد دیگر

Nikolaos Louros is an Assistant Professor at UT Southwestern Medical Center, with dual affiliations to the Center for Alzheimer's and Neurodegenerative Diseases (CAND) and the Department of Biophysics. He leads the Louros Lab, which focuses on protein misfolding, aggregation, and amyloid formation in neurodegenerative diseases. His research integrates AI-driven protein engineering with biophysical, structural, and cellular methods to develop novel therapeutics. B.S. in Biology, National and Kapodistrian University of Athens (2011) MSc in Bioinformatics (2014) Ph.D. in Cell Biology and Biophysics, NKUA (2016) Postdoctoral training at VIB-KU Leuven Center for Brain & Disease Research, Belgium Dr. Louros' research centers on the molecular mechanisms of protein aggregation, particularly in Alzheimer’s and Parkinson’s diseases. His lab investigates amyloid polymorphism, heterotypic interactions, and the role of post-translational modifications like glycosylation in proteostasis. Using computational tools and experimental validation, his team aims to identify aggregation modifiers and design novel inhibitors. His recent publications reveal a strong focus on amyloid structure, calcium dysregulation, and therapeutic targeting. Key themes include tau and Aβ polymorphism, co-aggregation with proteins like Medin, and the use of AI to map aggregation-prone sequences. His work frequently appears in top-tier journals such as Nature , Science , Cell , and Nature Reviews Molecular Cell Biology . Pharmacological modulation of septins in Alzheimer’s models Medin-Aβ co-aggregation in vascular amyloid AI-guided mapping of amyloid sequence space Structural basis of tau polymorphism Therapeutic targeting of pathogenic tau seeds Dr. Louros has not been listed with formal scientific awards in the provided text, but his publication record and leadership role indicate significant recognition. He is actively mentoring students and postdocs, as his lab is recruiting for Ph.D. candidates and research associates. The Louros Lab operates within the Peter O'Donnell Jr. Brain Institute, fostering interdisciplinary collaboration in neuroscience and biophysics. The lab employs a hybrid, inquiry-driven approach, combining deep learning, protein engineering, and high-throughput experimentation. It maintains strong collaborative ties with leading institutions and researchers in the field of neurodegeneration and protein science.

Shota Atsumiمشاهده پروفایل

استاد

• Synthetic Biology
• Metabolic Engineering
• Biofuel Production
• +۳ مورد دیگر

Professor Shota Atsumi is affiliated with the Department of Chemistry at the University of California, Davis . His research focuses on synthetic biology , metabolic engineering , and microbial chemical production , particularly for biofuels , rare sugars , and human milk oligosaccharides . He leads the Atsumi Lab, which has secured grants such as the NSF EFRI ELiS grant (award #2223537) for 3D-printed living materials and an NIGMS R01 grant for HMO production. His lab trains students and researchers in biocatalysis , carbon fixation , and microbial systems , with alumni like Jayce Taylor (PhD 2020-2024) and Jake Gonzales (PhD 2018-2023). He has served as an Associate Editor for Microbial Cell Factories and presented at conferences like the Metabolic Engineering Conference 16 (2025) and SynBioBeta 2024 . His work bridges synthetic biology with material science to address sustainability in construction and chemical production.