- Bioinformatics
- Genomics
- Computational Biology
- +۳ مورد دیگر
Dr. Xianghong Jasmine Zhou is a Professor in the Department of Pathology and Laboratory Medicine at the University of California, Los Angeles (UCLA) School of Medicine . Her work focuses on integrating genomic , epigenetic , and bioinformatic approaches for non-invasive cancer detection and monitoring through cell-free DNA analysis . Principal Investigator for multiple NIH grants (R01CA246329, U01CA230705, etc.) Developed software tools ( cfSNV , cfTools , CancerDetector ) for cell-free DNA mutation and methylation analysis Co-developed CancerLocator and HCC EV ECG score for tumor-of-origin prediction and hepatocellular carcinoma monitoring Research Interests: Specializes in 3D genome modeling , epigenetic regulation , and machine learning for liquid biopsy applications. Her work bridges computational biology with clinical translation , particularly in cancer diagnostics and treatment response assessment . Scientific Contributions: She has pioneered deep learning and population-based modeling approaches for cell-free DNA deconvolution , isoform-level functional annotation , and multi-omics integration . Her 2016 Cell paper on alternative splicing has been highly influential, with over 266 mentions.











