جستجوی استاد راهنمای دانشگاهی

Dr. Samira Lakhal-Littleton is an Associate Professor of Cell Physiology and MRC Senior Non-Clinical Research Fellow at the University of Oxford, affiliated with the Department of Physiology, Anatomy and Genetics and Brasenose College. Her research focuses on iron homeostasis, systems biology, and oxygen sensing mechanisms in cardiovascular and systemic physiology. Education: BSc in Human Genetics (University College London), DPhil in Molecular Medicine (University of Oxford) Her work bridges cell physiology and translational medicine, with key discoveries on hypoxia-inducible factors (HIFs), iron regulatory genes TMPRSS6 and GDF15 , and the role of hepcidin in altitude adaptation and chronic diseases. She utilizes tissue-specific animal models to study iron regulation in heart, kidney, placenta, and vasculature. Recent publications highlight her contributions to understanding: FLASH radiotherapy effects linked to iron-dependent lipid peroxidation Clinical implications of myocardial iron dynamics in heart failure Hepcidin's role in vascular protection and placental iron transfer Biomarker development for predictive iron deficiency diagnostics Scientific Leadership: British Heart Foundation Intermediate Fellowship (2012) MRC Senior Fellowship (2020) BioIron Society Board Member (2019) She collaborates with clinical teams on translational projects and serves as a Tutorial Fellow in Medicine at Brasenose College, mentoring students in physiological sciences.

• Iron Homeostasis
• Cell Physiology
• Systems Biology
• +۴ مورد دیگر

Calliope Dendrou is an Associate Professor in Clinical Pathology and Inflammation at the Kennedy Institute of Rheumatology (KIR), University of Oxford, leading the Immune Disease Multiomics Laboratory. She previously held a Wellcome & Royal Society Sir Henry Dale Fellowship at the University of Oxford’s Centre for Human Genetics before joining KIR in 2023. Her research focuses on immune disease mechanisms using multiomics approaches, including genomic profiling to identify therapeutic targets across tissues and immune-mediated diseases. She co-leads large-scale projects like the Oxford-J&J Cartography Consortium and the Chan Zuckerberg Initiative’s LEGACY Network, and teaches on the MSc in Genomic Medicine program. Educational Background: BSc (Biology, Imperial College London, 2005; Forbes Memorial Medal Winner); PhD in Infection & Immunity (University of Cambridge, 2010). Postdoctoral training at the Weatherall Institute of Molecular Medicine under Prof. Lars Fugger. Research interests include immunogenetics, cytokine signaling pathways, drug repositioning, and cross-disease pathophysiology. Her work integrates single-cell and spatial transcriptomics to dissect immune-cell interactions in diseases like rheumatoid arthritis, inflammatory bowel disease, and celiac disease. Recent articles highlight her contributions to understanding vaccine adjuvant responses, Th17 cell roles in spondyloarthritis, and immune-epithelial networks in celiac disease. Collaborations emphasize multi-omic data analysis (e.g., Panpipes pipeline) and translational studies toward precision medicine. Awards: Forbes Memorial Medal (BSc), Wellcome & Royal Society Sir Henry Dale Fellowship. Leadership roles include Equality, Diversity, and Inclusion Champion and 'Single-Cell & Spatial Omics for Precision Medicine' Module Lead. Lab & Teams: Immune Disease Multiomics Lab at KIR. Active in collaborative initiatives such as the LEGACY Network, focusing on large-scale immune profiling in ancestrally diverse populations.

• Immunology
• Genomics
• Multiomics Analysis
• +۳ مورد دیگر

Professor John Pickett serves as Chair of the School of Chemistry at Cardiff University, where he holds the position of Professor of Biological Chemistry. His research program has established him as a leading figure in chemical ecology with significant contributions to understanding chemically mediated interactions between organisms. Professor Pickett's research focuses on chemical ecology involving chemically mediated interactions between various organisms, particularly pests attacking plants and animals. His work encompasses the chemical characterisation of pheromones and other semiochemicals across plants and animals, including insect pests and beneficial organisms. He investigates stress-related chemical signalling by plants and vertebrates (including humans and farm animals), elucidates biosynthetic pathways to pheromones and other semiochemicals, and explores how these compounds can be exploited in pest management through ecological approaches and genetic modification. Analysis of Professor Pickett's recent publications reveals a sustained and impactful research trajectory spanning chemical ecology, agricultural science, and sustainable development. His work demonstrates remarkable continuity in investigating semiochemicals and pheromones while expanding into interdisciplinary areas including AI applications for sustainable futures and the economic impacts of agricultural innovations. A consistent theme throughout his career is the practical application of chemical ecology principles to develop sustainable pest management solutions, particularly through the development and refinement of push-pull farming systems that have transformed agricultural practices in Africa.

• Chemical Ecology
• Pheromone Research
• Semiochemicals
• +۶ مورد دیگر

Professor David Grainger is a faculty member at the University of Birmingham's School of Biosciences, specializing in Molecular Microbiology. He leads the Grainger Lab, focusing on bacterial chromosome biology, pathogenicity, and antibiotic resistance. His research integrates high-throughput techniques and single-molecule analysis to study gene regulation and bacterial pathogenesis. Education: PhD (2004), PGCE (2000), BSc (1999) in Biochemistry from the University of Birmingham. Affiliations: Part of the Institute of Microbiology and Infection (IMI), collaborating with experts in genomics, proteomics, and structural biology. Research Interests: Deciphering chromosome biology of pathogenic bacteria, including transcriptional regulation, toxin production control, and antibiotic resistance pathways. Utilizes cutting-edge methods like Hi-C for 3D chromatin analysis and single-molecule microscopy. Recent Articles: Focused on transposon capture mechanisms, bacterial promoter diversity, and quorum sensing signaling. Highlights include studies on Salmonella regulons and Vibrio cholerae biofilm suppression. Awards: Wellcome Trust Career Development Fellowship (2008), Runner-up in 'Science Snaps' competition for scientific communication. Grants: Career Development Fellowship-funded establishment of his research group at the University of Warwick (2008). Labs/Teams: Grainger Lab at the University of Birmingham, part of the IMI network. Engages in public science outreach via Twitter and lab website.

• Bacterial Chromosome Biology
• Pathogenicity
• Antibiotic Resistance Mechanisms
• +۳ مورد دیگر

Professor Wolfgang Wüster is a Professor in Zoology (Molecular Ecology) at Bangor University's School of Environmental and Natural Sciences. His research focuses on evolutionary biology, snake systematics, and venom toxicology, using snakes as model systems. He teaches courses in zoology and herpetology, including Arizona fieldwork and advanced herpetology modules. Education: PhD in Systematics of Asian cobras from the University of Aberdeen (1990). His research interests include the evolution of venom composition, species delimitation in snake complexes, warning signals, biogeography, and conservation genomics. He supervises postgraduate students in topics like European viper conservation and snake systematics. Recent publications highlight his work on snake venoms, taxonomy, and the impacts of climate change on reptile species. He collaborates globally, contributing to antivenom efficacy studies and venom evolution research. Professor Wüster has been involved in projects such as genomic studies of adders and the phylogeography of vipers. His work bridges molecular ecology with conservation, emphasizing practical applications in biodiversity preservation.

• Evolutionary Biology
• Snake Systematics
• Venom Toxicology
• +۵ مورد دیگر

Professor Guy Williams is a leading academic at the University of Cambridge with a focus on imaging science and clinical neurosciences, affiliated with Downing College and the Wolfson Brain Imaging Centre . Holding a PhD in Physics from his initial Natural Sciences degree, he specializes in nuclear magnetic resonance (NMR) and MRI techniques for brain imaging. Education: BA, PhD in Physics His research centers on non-invasive imaging of brain structure and function, particularly in traumatic brain injury (TBI) and dementia. His work involves developing novel MRI pulse sequences and advanced data analysis algorithms, including AI-based diagnostic tools. He leads studies on white matter integrity post-trauma, longitudinal dementia assessment, and applications of MRI in disorders of consciousness and addiction. Recent publications highlight collaborations in traumatic brain injury outcomes, AI-guided dementia prediction, and neuroimaging of post-COVID cognitive deficits. His team's work on ultra-high field laminar fMRI and distortion correction methods has advanced clinical neuroscience applications. Key techniques include diffusion tensor imaging (DTI), 7 Tesla MRI, and positron emission tomography (PET/MR). His research spans from basic NMR physics to clinical translation, with a strong emphasis on multi-site studies and real-world diagnostic implementation.

• Nuclear Magnetic Resonance (NMR)
• In vivo imaging
• MRI pulse sequence development
• +۷ مورد دیگر

Colin J Akerman is Professor of Neuroscience and Group Leader in the Department of Pharmacology at the University of Oxford, concurrently serving as Corange Fellow and Medical Tutor at Corpus Christi College. His research investigates fundamental mechanisms of synaptic circuit formation and plasticity, with direct implications for epilepsy, dementia, and schizophrenia through multidisciplinary approaches integrating electrophysiology, optical imaging, and computational modeling. His primary research interests encompass Synaptic Plasticity, Neural Circuit Formation, and Excitatory-Inhibitory Balance, with specific focus on neuronal progenitor influences on connectivity, chloride dynamics in inhibitory transmission, and learning mechanisms in disease contexts. The lab employs custom-built equipment and molecular tools to probe synaptic function across in vivo , in vitro , and in silico platforms, emphasizing how activity-dependent processes shape neural networks during development and disease. Recent publications (2023-2025) reveal strong thematic convergence on intracellular chloride regulation in sleep-wake cycles, cortical circuit assembly from embryonic progenitors, and innovative optical tools for neural monitoring. This work bridges molecular neuroscience with systems-level understanding of synaptic plasticity, particularly regarding ionic mechanisms in epilepsy and sleep homeostasis. No scientific awards or fellowships are explicitly documented in the source materials. Professor Akerman currently mentors four PhD students (Vourvoukelis, Selfe, Wang, Gemayel) and multiple postdoctoral researchers, having previously trained scientists now leading independent groups in Toronto, Edinburgh, Cape Town, Oxford, and London. His research is funded by the European Research Council, Innovative Medicines Initiative, and Wellcome Trust, supporting investigations into synaptic mechanisms underlying neurological disorders. The Akerman Group, established in 2008, operates as an integrative neuroscience hub within Oxford's Pharmacology Department. The 10-member team combines expertise in patch-clamp electrophysiology, optogenetics, multiphoton imaging, and computational modeling, with current projects spanning neuronal progenitor biology, inhibitory synaptic plasticity, and learning rule implementation in neural networks. The lab emphasizes technical innovation, regularly developing custom instrumentation and molecular tools for neural observation and manipulation.

• Neuroscience
• Synaptic Plasticity
• Neural Circuit Formation
• +۴ مورد دیگر

Silvia Santos is a Group Leader at the Francis Crick Institute, leading the Quantitative Stem Cell Biology Lab since January 2018. Her research focuses on understanding cell decision-making during transitions, specifically cell division and differentiation in early development using human embryonic stem cells. She combines experimental techniques with theoretical approaches, including advanced microscopy, genomics, and computational modeling. Education and Career: PhD in Molecular and Cell Biology from EMBL-Heidelberg (2008), followed by postdoctoral training at Stanford University (2009-2014). She held an MRC Career Development Award at Imperial College London (2014-2017) before joining the Crick. Her work emphasizes interdisciplinary methods to study cellular processes in health and disease. Research Interests: Spatial-temporal control in cell decisions, stem cell differentiation, cell cycle regulation, and modeling embryonic development. She advocates for women in science and mentorship programs for early-career researchers. Key Achievements: Recipient of Marie Curie E-Star, EMBO, and HFSP fellowships. Recognized with the BioModels’ Model of the Year 2023 for contributions to systems biology. Her lab develops models like gastruloids to study embryonic development. Grants and Mentorship: Supported by MRC and other grants. Committed to fostering excellence in training and mentorship, previously chairing mentorship initiatives at Imperial College London. Labs and Teams: Quantitative Stem Cell Biology Lab at the Crick, collaborating with interdisciplinary teams on projects involving proteomics, genomics, and high-throughput screening.

• Developmental Biology
• Cell Biology
• Cell Cycle & Chromosomes
• +۳ مورد دیگر

Laia Becares is a Professor of Social Science and Health at King's College London, part of the School of Global Affairs and the Department of Global Health & Social Medicine. She previously held roles at the University of Sussex (2018-2022) and the University of Manchester (2010-2018), where she maintains an Honorary position. She serves as an Editor of Sociology of Health and Illness and on the Academic Reference Group of the NHS Race and Health Observatory. Her work is funded by organizations such as the Nuffield Foundation and the Health Foundation. Laia holds a PhD in Social Epidemiology from University College London (UCL) and a Master's in Public Health from Boston University School of Public Health. Her research employs an interdisciplinary approach, collaborating with sociologists, psychiatrists, geographers, and demographers to understand how discrimination and marginalization perpetuate social and health inequities. Key areas include racism, homophobia/heterosexism, LGBTQ+ inequalities, and the impact of systemic oppression across life stages. She co-developed the Queerantine Study on pandemic impacts on LGBTQ+ communities and leads the ESRC Centre for Society and Mental Health, fostering student mentorship in health inequality topics. Her scientific awards include ESRC/MRC Postdoctoral Research Fellowship (2010-2012), Hallsworth Research Fellowship (2012-2016), and ESRC Future Research Leader Fellowship (2012-2015). Recent work focuses on ethnic healthcare disparities in multimorbidity and longitudinal studies of racism's effects on health outcomes. Ongoing projects include LGBTQ+ policymaking networks and the GHSM Anti Racism Steering Group, addressing structural inequities in academia and healthcare. Laia’s grants include Nuffield Foundation funding for ethnic inequalities in later life and Health Foundation support for healthcare equity studies. She advocates for integrating lived experiences into research design, particularly through the Evidence for Equality National Survey (EVENS). Her lab affiliations include Queer@King’s and the ESRC Centre for Society and Mental Health, emphasizing collaborative, community-driven approaches.

• Social Epidemiology
• Health Inequalities
• Racism and Health
• +۳ مورد دیگر

Dr. Megan Bergkessel is a Research Professor in Molecular Microbiology at the University of Dundee's School of Life Sciences. Her research focuses on understanding how bacteria like Pseudomonas aeruginosa regulate activities during growth arrest, particularly in resource-limited environments. This work addresses antibiotic tolerance mechanisms critical to chronic infections. Principal Investigator leading studies on non-growing bacterial physiology Recipient of a £900k UKRI Future Leaders Fellowship (2020) Expertise in antimicrobial resistance and microbial stress responses Current research explores regulatory pathways enabling protein synthesis in non-growing states, with implications for developing novel infection treatments. Supervises PhD projects investigating two-component signaling systems and environmental sensing in P. aeruginosa. Recognized for teaching excellence in Biological and Biomedical Sciences programs. PhD opportunities: Adaptive antimicrobial resistance mechanisms and environmental sensing roles Media commentary available via Corporate Communications

• Molecular Microbiology
• Antimicrobial Resistance
• Bacterial Physiology
• +۳ مورد دیگر

Darryl Overby is a Professor of Mechanobiology in the Department of Bioengineering at Imperial College London's Faculty of Engineering. His academic affiliations include the CRUK Convergence Science Centre, Cancer Technology Network, and multiple interdisciplinary networks focused on ocular biomechanics, vascular science, and regenerative medicine. He holds an Orcid identifier (0000-0001-9894-7515) and was previously affiliated with Tulane University and Harvard Medical School. Education: Ph.D. in Mechanical Engineering (2002) from MIT under Prof. Roger Kamm, followed by postdoctoral research at Harvard Medical School under Prof. Donald Ingber. His work focuses on cellular biomechanics, mechanotransduction, and the role of mechanical forces in intraocular pressure regulation and glaucoma pathophysiology. Research interests span mechanobiology of Schlemm’s canal endothelial cells, nitric oxide signaling in ocular tissues, and development of organ-on-chip models for studying aqueous humor outflow dynamics. His lab explores how mechanical signals drive transcellular pore formation and how these mechanisms fail in glaucomatous conditions. Key contributions include consensus guidelines for Brillouin microscopy measurements, ex vivo perfusion studies, and the role of TRPV4 channels in mechanosensing. His work integrates engineering techniques with clinical ophthalmology to advance therapies targeting glaucoma and ocular hypertension. Professional activities include leadership roles in the Ocular Biomechanics Network and Wound Healing and Regeneration Network. His research has led to patents for devices enhancing aqueous humor drainage and RNAi-based therapies.

• Mechanobiology
• Ophthalmology
• Biomedical Engineering
• +۴ مورد دیگر

Dr. Thomas A. Hughes is an Associate Professor of Cancer Biology at the University of Leeds and Professor of Biosciences at York St John University. As a Group Leader at the Leeds Institute of Medical Research, he focuses on gene regulation, tumour microenvironment, and nanomedicine approaches to improve cancer outcomes. Specializes in breast cancer, colorectal cancer, and rare diseases Develops therapeutic strategies using microRNAs and biomarkers Collaborates with clinicians, engineers, and chemists for translational research His research integrates molecular pathology with clinical data through partnerships with Leeds NHS Trusts, aiming to identify novel biomarkers and targets for therapy. Recent work emphasizes cholesterol metabolism, oxysterol signaling, and nanomedicine-based drug delivery systems. Key contributions include: Over 80 peer-reviewed publications in cancer biology and molecular therapeutics Leadership in MSc programs in Molecular Medicine and Cancer Biology and Therapy Extensive experience in grant review, editorial work, and doctoral supervision Scientific awards include Fellowship of the Higher Education Academy. His lab has mentored 26 doctoral students and numerous alumni in academia, clinical practice, and industry.

• Cancer Biology
• Gene Regulation
• Breast Cancer
• +۶ مورد دیگر

Sharon Abrahams is a Professor of Neuropsychology and holds a Personal Chair at the University of Edinburgh's School of Philosophy, Psychology and Language Sciences. She leads research in clinical and experimental neuropsychology, focusing on neurodegenerative diseases like motor neurone disease/ALS and frontotemporal dementia. Her work integrates neuroimaging, cognitive assessment, and clinical intervention. She is affiliated with the Euan MacDonald Centre for Motor Neurone Disease, the Centre for Clinical Brain Sciences, and Edinburgh Neuroscience. Current PhD students include Monica de Icaza Valenzuela, Debbie Gray, and Caroline McHutchison. Abrahams has secured over 17 research grants since 2008, including projects on cognitive screening in MND, apathy impact, and the ECAS tool. Her research emphasizes cognitive and behavioral changes in ALS, with a focus on early detection, staging, and patient quality of life. Notable contributions include the Edinburgh Cognitive and Behavioural ALS Screen (ECAS), validated across multiple languages and populations.

• Clinical Neuropsychology
• Neuroimaging
• Neurodegenerative Diseases
• +۴ مورد دیگر

Yang Luo is a Kennedy Trust Senior Research Fellow in Data Science at the University of Oxford's Kennedy Institute of Rheumatology. His research bridges statistical genomics and computational immunology to unravel genetic contributions to immune-mediated traits, with a focus on the major histocompatibility complex (MHC) region. His work leverages large biobank datasets (UK Biobank, Biobank Japan), gene expression resources (GTEx), and proteomic data to decode molecular mechanisms linking genetic variation to disease risk. Specific interests include tuberculosis genetics, multi-ancestry polygenic risk scores, and single-cell eQTL modeling. Recent publications highlight expertise in HLA association studies, evolutionary immunogenetics, and disease-specific cell state dynamics. Key contributions include constructing a global HLA haplotype panel and developing novel statistical methods for admixed population genetics. Scientific Awards: Kennedy Trust Senior Research Fellow in Data Science His lab integrates computational and experimental approaches to translate genetic findings into clinical applications for immune disorders.

• Statistical Genomics
• Computational Immunology
• Human Genetics
• +۲ مورد دیگر

Robert Fletcher is a Researcher at the University of Cambridge, affiliated with the Department of Zoology and the C-CLEAR Doctoral Training Partnership . His work focuses on applied ecology and conservation science, utilizing landscape and population ecology to address biodiversity challenges globally. Research Areas : Conservation biology, population ecology, landscape ecology, environmental informatics Collaborations : Partners in North America, Europe, Africa, and Southeast Asia Key Themes : Species extinction prevention, landscape conservation prioritization, and rapid biodiversity data delivery Email : rf497@cam.ac.uk Fletcher's interdisciplinary approach integrates fieldwork (e.g., Everglades endangered species, African elephants) with advanced modeling of habitat loss, fragmentation, invasive species, and climate change impacts. His recent work emphasizes: Drivers of species decline and recovery strategies Landscape management and restoration techniques Interdisciplinary collaborations with engineers, social scientists, and computer scientists His publications span topics like savanna ecosystem dynamics, community science applications, and conservation forecasting, reflecting a commitment to actionable science for global biodiversity preservation.

• Conservation ecology
• Population ecology
• Landscape ecology
• +۳ مورد دیگر