معرفی
Yang Luo is a Kennedy Trust Senior Research Fellow in Data Science at the University of Oxford's Kennedy Institute of Rheumatology. His research bridges statistical genomics and computational immunology to unravel genetic contributions to immune-mediated traits, with a focus on the major histocompatibility complex (MHC) region.
His work leverages large biobank datasets (UK Biobank, Biobank Japan), gene expression resources (GTEx), and proteomic data to decode molecular mechanisms linking genetic variation to disease risk. Specific interests include tuberculosis genetics, multi-ancestry polygenic risk scores, and single-cell eQTL modeling.
Recent publications highlight expertise in HLA association studies, evolutionary immunogenetics, and disease-specific cell state dynamics. Key contributions include constructing a global HLA haplotype panel and developing novel statistical methods for admixed population genetics.
- Scientific Awards:
- Kennedy Trust Senior Research Fellow in Data Science
His lab integrates computational and experimental approaches to translate genetic findings into clinical applications for immune disorders.
