جست‌وجوی استاد و پژوهشگر

W. Walter Lorenzمشاهده پروفایل

پژوهشگر

• Genomics
• Bioinformatics
• Molecular Biology
• +۶ مورد دیگر

W. Walter Lorenz is an Assistant Research Scientist at the Georgia Genomics and Bioinformatics Core, University of Georgia. His research spans genomics, bioinformatics, and molecular biology with a focus on plant genetics, parasitology, and gene expression analysis. He leads the Georgia Genomics and Bioinformatics Core, providing advanced genomic tools and data analysis services. Research interests include understanding molecular mechanisms in plant defense responses, parasite-host interactions, and genomic approaches to study complex organisms like conifers and myxozoans. His work integrates transcriptomics, proteomics, and bioinformatics to address questions in evolutionary biology, stress physiology, and disease resistance. Key contributions include decoding the loblolly pine genome, developing genomic databases for conifers, and analyzing gene networks in drought-stressed plants. He has also explored microbial genomics, immunology, and animal physiology through studies on Chlamydia infections, natural killer cell biology, and avian reproduction. Notable projects involve Sirex woodwasp interactions with pines, myxozoan parasite evolution, and the functional characterization of glycosylation pathways in human immune cells. His research bridges basic science and applied challenges in agriculture, forestry, and human health. No scientific awards are explicitly mentioned in the provided texts. His work is supported by collaborations across disciplines and institutions, though specific grant details are not detailed here. He advises no listed students but contributes to training through his core facility.

Ihab Younisمشاهده پروفایل

استاد آموزشی

• Intron Splicing
• Gene Expression Regulation
• Cancer Biology
• +۳ مورد دیگر

Ihab Younis is a Teaching Professor in the Department of Biological Sciences at Carnegie Mellon University , leading the Biological Sciences Program at CMU Qatar. He holds a Ph.D. in Molecular, Cellular, and Developmental Biology from The Ohio State University, with M.S. and B.S. degrees in Biology from the American University of Beirut. His research focuses on post-transcriptional regulation of gene expression , particularly intron splicing mechanisms and their role in cancer. His lab employs cutting-edge techniques like RNA-seq and high-throughput screening to study splicing defects in cancer cells and has identified novel splicing regulators. A key focus is the role of minor introns as stress-induced molecular switches, mediated by the unstable U6atac snRNA component of the minor spliceosome. Younis teaches courses including Genetics, Molecular Biology, Virology, and Cancer Biology. His lab integrates computational and experimental approaches, including projects exploring splicing aberrations in cancer and mechanisms controlling mRNA length. He has published extensively on splicing regulation, HTLV viral replication, and the SMN complex's role in RNP assembly. His work bridges basic science and translational research, aiming to uncover therapeutic targets for cancer and viral diseases. Despite no explicitly listed awards, his contributions to splicing mechanisms and stem cell applications highlight impactful academic leadership.

Briana Burtonمشاهده پروفایل

دانشیار

• Membrane Transport Mechanisms
• Bacterial Genetics
• Microbiology
• +۳ مورد دیگر

Briana Burton is an Associate Professor of Bacteriology at the University of Wisconsin-Madison, leading the Burton Lab. Her research focuses on understanding mechanisms of DNA translocation across bacterial membranes, particularly during sporulation and antibiotic resistance. She holds a B.A. in Molecular and Cell Biology from Northwestern University (1998) and a Ph.D. in Biology from MIT (2003), followed by postdoctoral research at Harvard Medical School. Her lab employs interdisciplinary approaches, including biochemistry, microscopy, and molecular biology, to study DNA transport complexes in Bacillus subtilis . Key research areas include chromosome segregation during sporulation, competence pili dynamics, and engineering bacteria for DNA detection. She teaches courses such as Microbiology 470 and Micro 612, emphasizing microbial genetics and molecular machines. Current lab members include graduate students (Jonathan Lombardino, Dom Smith), postdoctoral researchers, and technical staff. The lab actively recruits undergraduates, graduate students, and postdocs. Recent publications highlight advancements in DNA transport mechanisms, genetic code expansion, and bacterial co-culture dynamics.

Bogdan Ditمشاهده پروفایل

دانشیار بالینی

• Software Engineering
• Empirical Software Engineering
• Data Mining
• +۳ مورد دیگر

Bogdan Dit is a Clinical Associate Professor in the Department of Computer Science at Boise State University. He holds a Ph.D. from The College of William and Mary, an M.S. from Wayne State University, and a B.S. from Babeș-Bolyai University. His research focuses on software engineering, empirical methods, and tool development for tasks like feature location, impact analysis, and traceability. He is affiliated with the SEMERU Research Group and has contributed to projects such as TraceLab Component Library and Impactminer. His work emphasizes reproducible research and developer tools for software maintenance. Education: Ph.D., Computer Science, College of William and Mary (Advisor: Dr. Denys Poshyvanyk) M.S., Computer Science, Wayne State University (Advisor: Dr. Andrian Marcus) B.S., Computer Science, Babeș-Bolyai University Research Interests: Empirical software engineering, feature location, software traceability, genetic algorithms, data fusion, and developer tool development. His work combines empirical studies with tool-based solutions to address challenges in software maintenance and evolution. Key Contributions: Developed TraceLab for reproducible experiments, Impactminer for change impact analysis, and Traceclipse for traceability management. His research often integrates information retrieval and machine learning techniques to enhance software engineering practices. Labs/Teams: Affiliated with the SEMERU Research Group, focusing on software evolution and maintenance.

• Protein Biochemistry
• Molecular Biophysics
• Structural Bioinformatics
• +۵ مورد دیگر

Daniele Dell'Orco is an Associate Professor of Biochemistry and Bioinformatics at the University of Verona's Department of Neurosciences, Biomedicine and Movement Sciences. He holds roles including PhD program tutor, laboratory director, and membership in academic governance bodies such as the Faculty Board of Biomolecular Medicine. His research focuses on neuronal calcium sensors, phototransduction mechanisms, and retinal dystrophies, with a particular emphasis on molecular therapies using biologics. Research Interests : Protein biochemistry, molecular biophysics, structural bioinformatics, systems biology, and translational medicine targeting sensory disorders. His work integrates experimental and computational approaches to study calcium sensor proteins in health and disease, including their roles in phototransduction and mechano-transduction pathways. Teaching & Supervision : Teaches courses in biochemistry, molecular biology, and translational medicine across undergraduate and postgraduate programs. Supervises bachelor/master students and PhD candidates in the Biomolecular Medicine program. His teaching spans disciplines like biological macromolecules, medical genetics, and clinical biochemistry. Labs & Collaborations : Leads an independent lab investigating biomedical topics from a molecular perspective. Collaborates nationally and internationally on projects such as lipid-based therapeutics for retinal degeneration and PRIN-funded research on protein variant interpretation. His lab utilizes advanced techniques including molecular dynamics simulations and nanobiophysics. Funding & Projects : Secured grants for initiatives like the FFABR 2017 award and PRIN 2017 project on protein variant analysis. Research topics include GCAP1's role in retinal dystrophies and CIB2's involvement in Usher syndrome. Partnerships involve WHO Collaborating Centers and cross-departmental collaborations within the University of Verona.

• Bioenergetics
• Photosynthesis
• Cyanobacteria research
• +۵ مورد دیگر

Professor Thomas Friedrich is a distinguished faculty member at the Technical University of Berlin, where he leads the Department of Physical Chemistry/Bioenergetics within the Faculty of Mathematics and Natural Sciences. His research group focuses on energy conversion processes in biological systems, with particular emphasis on photosynthesis in cyanobacteria and electrophysiological studies of ion channels and transporters. Professor Friedrich's research spans two primary domains: bioenergetics of photosynthetic systems and membrane transport mechanisms. In photosynthesis research, his group investigates excitation energy transfer processes between light-harvesting antenna proteins and reaction centers, with special focus on the orange carotenoid protein and other carotenoid-binding proteins from cyanobacteria. For membrane transport studies, his work examines voltage-gated ion channels (Kv channels), voltage-gated membrane-enzymes (PIP 3 -phosphatase Ci-VSP), and ATP-driven ion pumps (Na + /K + -ATPase, H + /K + -ATPase). Analysis of his recent publications reveals a strong focus on cyanobacterial photoprotection mechanisms, particularly involving orange carotenoid proteins (OCP), with numerous studies examining OCP structure, function, and interaction with fluorescence recovery protein (FRP). His work combines biochemical protein production with advanced spectroscopic techniques including UV-Vis absorption spectroscopy, Raman spectroscopy, and fluorescence spectroscopy using specialized laser detector systems for time-correlated single photon counting (TCSPC). Professor Friedrich's laboratory utilizes a range of sophisticated techniques, including two-electrode voltage-clamp (TEVC) experiments, voltage-clamp fluorimetry (VCF), and time-resolved spectroscopy. His group produces proteins with native carotenoid cofactors in Escherichia coli bacteria and performs functional studies to understand energy transfer processes at the molecular level. The department has specialized equipment for fluorescence lifetime measurements with picosecond accuracy, enabling detailed characterization of biological fluorophores.

Antonio Rausellمشاهده پروفایل

دانشیار

• Bioinformatics
• Genomics
• Machine Learning
• +۳ مورد دیگر

Antonio Rausell is an Associate Professor in Bioinformatics and Genomics at the University of Paris and Director of the Clinical Bioinformatics Lab at the Imagine Institute, INSERM UMR 1163. He is also a Hospital Practitioner at Necker Hospital of Sick Children, APHP. His research focuses on computational genomics, single-cell omics, and clinical decision support systems for rare genetic diseases, such as immune deficiencies and ciliopathies. Key contributions include the development of tools like NCBoost for non-coding variant analysis and CNVxplorer for clinical CNV interpretation. His work has been published in high-impact journals like Nature Biotechnology and Genome Biology. He leads the iCARP program to identify clinical markers and AI tools for diagnostics and treatment. Education: Engineering degree in Biotechnology, PhD in Bioinformatics (CNIO), postdoctoral research at SIB and University Hospital Lausanne. Research interests span genetic variant prediction, immune response variability, and functional genomics. His lab collaborates with clinical departments and experimental groups to bridge computational methods with clinical applications. Advising and Grants: Mentors PhD students (Requena, Favier, Montalvo) and oversees projects funded by the Imagine Institute and Milieu Intérieur Consortium. Lab members include engineers and invited scientists, fostering interdisciplinary collaboration. Labs/Teams: Clinical Bioinformatics Lab at Imagine Institute, part of broader collaborations in functional genomics and immune system research.

Han Xiaoمشاهده پروفایل

دانشیار

• Chemical Biology
• Medicinal Chemistry
• Cancer Immunology
• +۳ مورد دیگر

Han Xiao is an Associate Professor and Associate Chair for Graduate Admissions in the Department of Chemistry at Rice University, where he also serves as Director of the SynthX Center and is a CPRIT Scholar in Cancer Research. His research focuses on interdisciplinary approaches at the chemistry-biology interface, developing chemical tools to probe and manipulate biological systems. Research interests include organic synthesis, chemical biology, medicinal chemistry, glycobiology, and cancer immunology, with applications in cancer therapeutics, autoimmune diseases, and metabolic disorders. His work emphasizes translational potential for clinical applications. Recent publications demonstrate strong focus on cancer biology, novel imaging techniques, protein engineering, and therapeutic development. Key themes include bone metastasis mechanisms, advanced bioconjugation methods, fluorescent probes for biological detection, and light-activated systems. Dr. Xiao has received significant recognition including the DOD Breast Cancer Research Breakthrough Award, NIH Maximizing Investigators' Research Award, Norman Hackerman-Welch Young Investigator Award, and CPRIT Faculty Recruitment Award. He leads the Xiao Research Group at Rice University, focusing on innovative chemical biological tools for understanding biological systems and developing therapeutic strategies.

Vishal Patelمشاهده پروفایل

استاد

• Polycystic Kidney Disease
• RNA Therapeutics
• RNA Metabolism
• +۳ مورد دیگر

Vishal Patel, MBBS, is a Professor in the Department of Internal Medicine at the University of Texas Southwestern Medical Center, specializing in Nephrology. He holds membership in the Division of Nephrology and is recognized as a Physician-Scientist. His academic trajectory includes an MBBS from P S Medical College (India), residency at Northwestern University, and fellowship training at UT Southwestern. He joined UT Southwestern as an Assistant Instructor in 2008, advancing to Assistant Professor (2009), tenure-accruing Assistant Professor (2010), and Associate Professor with Tenure (2018). His research focuses on polycystic kidney disease (PKD), RNA therapeutics, and kidney genetics, with notable contributions including patents for PKD treatments and NIH-funded studies on primary cilia biology. Dr. Patel’s work bridges clinical nephrology and molecular medicine, emphasizing microRNA regulation in kidney pathogenesis. Education MBBS, P S Medical College, India Internal Medicine Residency, Northwestern University, Chicago Clinical Nephrology Fellowship, UT Southwestern Medical Center Research Interests Dr. Patel’s lab investigates the molecular mechanisms underlying PKD, particularly the role of microRNAs in cyst formation and kidney dysfunction. His work explores RNA metabolism pathways, therapeutic oligonucleotides, and genetic modifiers of kidney disease. Recent studies highlight the interplay between primary cilia dysfunction, mTOR signaling, and metabolic pathways in cyst progression. His research also addresses translational applications, including miRNA-based therapies and biomarker development for PKD. Advising & Grants Supported by NIH grants as a Physician-Scientist, Dr. Patel has pioneered studies on miR-17 inhibition and mRNA stabilization for PKD. His patents for PKD treatments reflect clinical translation efforts. He collaborates extensively with nephrology teams and pharmaceutical partners to advance drug development. Labs/Teams Affiliated with the Division of Nephrology at UT Southwestern, he leads interdisciplinary projects involving geneticists, bioengineers, and clinicians to tackle kidney disease complexity.

Benjamí Oller Salviaمشاهده پروفایل

دانشیار

• Bioengineering
• Biomedical Engineering
• Drug Delivery Systems
• +۵ مورد دیگر

Benjamí Oller Salvia is an Associate Professor in the Bioengineering Department at IQS School of Engineering, Ramon Llull University. His research focuses on developing innovative bioengineering solutions for blood-brain barrier (BBB) transport and targeted therapeutic delivery using advanced peptide engineering and nanotechnology approaches. Institution: Ramon Llull University School: IQS School of Engineering Department: Bioengineering Department Research Overview Dr. Salvia's work centers on creating BBB-crossing peptides and masked antibody conjugates for improved delivery of therapeutics to the central nervous system. He pioneered the development of BrainBike peptidomimetics and zwitterionic nanovehicles for gene delivery across brain endothelium. His research combines bioorthogonal chemistry , noncanonical amino acid incorporation , and genetic code expansion to engineer conditionally active therapeutic agents. Publication Trends His recent publications (2021-2025) demonstrate expertise in peptide-based drug delivery systems , antibody engineering , and neurotherapeutic development . Key innovations include protease-resistant peptides , site-specific conjugation techniques , and stimuli-responsive activation mechanisms for enhanced therapeutic precision. Collaborations Dr. Salvia maintains extensive collaborations with institutions including the Institute for Research in Biomedicine (IRB Barcelona) , Medical Research Council , and University of Zaragoza , with a focus on multidisciplinary projects involving venom-derived peptides and protein transport mechanisms .

• Metabolic Disorders
• Diabetes Research
• Obesity Studies
• +۳ مورد دیگر

Silvia Corvera is a Professor of Molecular Medicine and holds the Endowed Chair in Diabetes Research at the University of Massachusetts Chan Medical School, within the T.H. Chan School of Medicine's Program in Molecular Medicine. She also serves as Director of the MD/PhD (MSTP) program and the Clinical Translational Research Pathway. Her academic journey includes an MD and MSc in Molecular Biology from the Universidad Nacional Autonoma de Mexico, followed by postdoctoral studies in the U.S. and faculty roles at the University of Pennsylvania and UMass Chan. Her research focuses on understanding cellular and molecular mechanisms underlying metabolic diseases such as type-2 diabetes, non-alcoholic fatty liver disease (NASH), and hypertension. Key areas include adipose tissue dynamics—specifically adipocyte expansion, brite/beige adipocyte function, and adipose organoid development. Collaborations with clinical partners in surgery and obstetrics-gynecology enhance translational research into metabolic disease associations with adipose distribution patterns. Dr. Corvera’s laboratory explores adipose tissue heterogeneity, including its role in energy homeostasis and therapeutic potential. Current projects involve analyzing adipose cell populations via single-cell RNAseq and investigating how genetic factors influence adipose patterning. Her work bridges basic science and clinical applications, addressing obesity-related pathologies and regenerative medicine opportunities. Notable contributions include defining adipose tissue angiogenesis in obesity, generating functional human adipose tissue in vivo, and elucidating mechanisms of adipocyte progenitor differentiation. Her lab actively engages trainees in rotation projects focused on adipocyte biology, cell signaling, and metabolic pathways. Lab activities emphasize interdisciplinary approaches, combining molecular biology, stem cell technology, and systems biology to advance treatments for metabolic disorders. Ongoing efforts investigate adipose-derived cell therapies, CRISPR-enhanced adipocyte browning, and the role of long noncoding RNAs in thermogenesis regulation.

Thomas Sakmarمشاهده پروفایل

استاد

• G Protein-Coupled Receptors (GPCRs)
• Drug Discovery
• Structural Biology
• +۵ مورد دیگر

Thomas P. Sakmar, M.D., is the Richard M. and Isabel P. Furlaud Professor at The Rockefeller University and a Senior Physician at The Rockefeller University Hospital. He leads the Laboratory of Chemical Biology and Signal Transduction, focusing on G protein-coupled receptors (GPCRs) and their role in drug discovery, cellular signaling, and human diseases. His research combines chemical, biophysical, and genetic methods to study transmembrane signaling mechanisms. Affiliations: Head of Laboratory, Tri-Institutional M.D.-Ph.D. Program faculty member, and former Acting President of Rockefeller University. Education: A.B. in Chemistry (University of Chicago, 1978), M.D. (University of Chicago Pritzker School of Medicine, 1982). Research Interests: Structural biology of GPCRs, rational drug design, protein engineering, and amyloidosis syndromes. Recent work includes studies on CYSLTR2 as a GPCR oncogene and novel chaperone proteins for amyloid disorders. His lab has pioneered methods like genetic code expansion and bioorthogonal labeling to advance drug discovery. Collaborations include work on HIV coreceptors and proteomic analysis of GPCR interactomes.

Jamie H. D. Cateمشاهده پروفایل

استاد

• Biochemistry
• Biophysics
• Structural Biology
• +۷ مورد دیگر

Jamie H. D. Cate is a Professor of Biochemistry, Biophysics and Structural Biology, and Chemistry at the University of California, Berkeley. He leads the Cate Lab, focusing on understanding protein synthesis mechanisms, particularly through the study of ribosomes and their roles in translation regulation. His work also involves engineering ribosomes to synthesize novel polymers, contributing to the Center for Genetically Encoded Materials (C-GEM). His research explores how genes are translated into proteins, specifically investigating the ribosome's role in this universal process. Key areas include understanding translation initiation regulation by eIF3, its role in cancer-related mRNA regulation, and viral hijacking mechanisms. Additionally, he pioneers methods to engineer ribosomes for producing non-natural polymers using mRNA templates. Techniques employed include cryo-electron microscopy, biochemistry, and systems biology. Recent studies highlight the lab's focus on eIF3's dual role in activating and repressing specific mRNAs, particularly in T cells and neural progenitor cells. The lab also investigates ribosome structural adaptations to incorporate non-canonical amino acids and the molecular basis of drug-induced ribosome stalling. These efforts aim to advance therapeutic strategies and synthetic biology applications. Lab affiliations: Cate Lab at UC Berkeley, part of the Department of Biochemistry, Biophysics, and Structural Biology, and the Center for Genetically Encoded Materials (C-GEM). No notable scientific awards are listed in the provided texts. Advising information and grant details are not explicitly mentioned here.

Alanna Schepartzمشاهده پروفایل

استاد

• Chemical Biology
• Synthetic Biology
• Biosynthesis of Polymers
• +۴ مورد دیگر

Alanna Schepartz is the CZ and Irmgard Distinguished Chair of Chemistry and Professor of Molecular Therapeutics at UC Berkeley's Department of Molecular and Cell Biology, within the College of Letters & Science. Her research spans chemical biology and synthetic biology, focusing on repurposing cellular machinery for novel applications. Current projects include ribosome engineering for polymer synthesis, CPMP-mediated protein delivery, EGFR membrane signaling, and HIDE probes for super-resolution imaging. The Schepartz Lab collaborates widely, including with the NSF Center for Genetically Encoded Materials (C-GEM). Notable tools developed include HIDE probes for organelle visualization and CPMPs for therapeutic delivery. Recent work highlights advancements in genetic code expansion, endosomal escape mechanisms, and organelle dynamics imaging. Education details are not explicitly listed, but her academic standing and leadership roles imply advanced training in chemistry/biochemistry. She advises graduate and undergraduate students, including recent graduates Lauren Lesiak, Angel Vazquez Maldonado, and others. Collaborations involve institutions like Yale University and Penn State, with ongoing efforts in NIH/NSF-funded projects. Future directions include expanding HIDE probe capabilities, optimizing CPMP delivery systems, and exploring allosteric signaling pathways in kinases. Research Themes: Ribosome repurposing, protein delivery, membrane signaling, organelle imaging Key Tools: HIDE probes, CPMPs, genetic code expansion platforms Collaborative Networks: NSF C-GEM, Yale Cell Biology Group

• Medical Genetics
• Genetic Disorders
• Genomics
• +۵ مورد دیگر

Asst. Prof. Serhat SEYHAN is affiliated with Uskudar University Faculty of Medicine's Department of Medical Genetics. He holds an MD from Cumhuriyet University (2011) and completed his medical genetics specialty at Karadeniz Technical University (2016). His research focuses on genetic disorders, cancer genetics, and rare diseases, with particular emphasis on genomic analysis techniques like optical genome mapping and next-generation sequencing. He has contributed to studies on motor neuron diseases, hearing loss mechanisms, and hereditary cancer gene variants. His work bridges clinical practice and molecular diagnostics, addressing translational challenges in genetic medicine. Notable contributions include identifying novel mutations in VRK1, MYH14, and GPR156 genes, and exploring liquid biopsy applications in cancer management. His articles span from 2014 to 2025, reflecting expertise in both rare genetic conditions and pandemic-related genetic factors in disease severity. Laboratory and team involvement is implied through collaborative genomic studies, though specific lab names are not mentioned. Grant and advisory roles remain unspecified in available texts.