جستجوی استاد راهنمای دانشگاهی

Vikramaditya G. Yadavمشاهده پروفایل

دانشیار

• Biocatalysis
• Bioremediation
• Bioprocess engineering
• +۱۵ مورد دیگر

Vikramaditya G. Yadav is an Associate Professor at the University of British Columbia (UBC) in the Department of Chemical and Biological Engineering, Faculty of Applied Science. He directs the Master of Engineering Leadership (MEL) Program in Sustainable Process Engineering and leads the BioFoundry research group. Education: B.A.Sc., University of Waterloo (2007) Ph.D., Massachusetts Institute of Technology (2013) Postdoctoral Associate, Harvard University (2014) His research spans sustainable chemical manufacturing, metabolic engineering, and biotechnology. Key areas include: Designing biosynthetic enzymes for biomass valorization Developing bioremediation strategies for industrial water quality Creating innovative drug delivery systems and tissue engineering solutions Advancing synthetic biology for pharmaceutical and bioenergy applications His recent work focuses on ocular drug delivery, cannabinoid biosynthesis in E. coli, lignin-based nanoparticles for cancer therapy, and computational analysis of plant secondary metabolites. Collaborations with start-ups, industry, and medical labs drive innovation in Canada's bioeconomy. Professional Leadership: Chair, Biotechnology Division of the Chemical Institute of Canada Associate Editor, The Canadian Journal of Chemical Engineering He is affiliated with UBC's BioProducts Institute and contributes to project-based learning pedagogy.

Johannes Larschمشاهده پروفایل

استادیار

• Neuroscience
• Social Behavior
• Neuronal Circuits
• +۳ مورد دیگر

Johannes Larsch is a tenure-track Assistant Professor at the Center for Integrative Genomics within the Faculty of Biology and Medicine at Université de Lausanne (UNIL). His research focuses on understanding the neuronal mechanisms underlying social interactions, using larval zebrafish as a model organism. He employs advanced techniques like virtual reality and optical imaging to study how social signals are processed in the brain. Education: Bachelor of Biology, University of Konstanz, Germany PhD in Neurobiology, Rockefeller University, USA (lab of Cori Bargmann) Postdoc at Max Planck Institute of Neurobiology, Germany (with Herwig Baier) Research interests center on neuronal circuits driving group behavior, social recognition, and the interplay between genetics and environment in shaping behavior. His lab investigates how individual brains coordinate collective social behaviors through studies of neuronal activity and circuit dynamics. Current lab openings include fully funded PhD and PostDoc positions focused on social neuroscience and neurogenomics. Contact: johannes.larsch@unil.ch .

Jonny Kohlمشاهده پروفایل

پژوهشگر

• Neuroscience
• Neural Circuits
• Behavioral Biology
• +۴ مورد دیگر

Jonny Kohl is a Group Leader at the Francis Crick Institute , where he established the State-dependent Neural Processing Laboratory in 2019. His work bridges neural circuits and internal physiological states (e.g., hunger, pregnancy) to decode instinctive behaviors like parenting and aggression in mice. PhD: MRC Laboratory of Molecular Biology, Cambridge (2013) Postdoc: Harvard University (2014–2019) with support from EMBO, HFSP, and Wellcome Trust fellowships Research Interests : Kohl investigates how hormonal and metabolic states dynamically rewire neural circuits to drive adaptive behaviors. His lab combines circuit neuroscience , molecular biology , and behavioral profiling to study: State-dependent neural processing in parental behavior Chemosensory dominance hierarchies in mice Plasticity mechanisms in aggression circuits Development of ultrafast tissue labeling and cryoanesthesia tools Scientific Trends : His recent publications highlight hormone-mediated synaptic remodeling (2023), cost-effective lab tools (2023), and brain-wide activity mapping (2016). Collaborative work spans computational biology , metabolism , and imaging disciplines. Honors: NARSAD Young Investigator Award (2019), ERC Starting Grant (2019), Wellcome Trust Discovery Award (2025) Grants: BBSRC Research Grant (2025), BBSRC Pioneer Grant (2023) His lab mentors PhD and MSc students and has developed open-source neuroscience tools (e.g., cryoanesthesia device, 2023). Kohl's research has been featured in Nature , Science , and Cell .

Michael Baymمشاهده پروفایل

دانشیار

• Microbial Evolutionary Genomics
• Antibiotic Resistance
• Computational Biology
• +۷ مورد دیگر

Dr. Michael Baym is an Associate Professor of Biomedical Informatics at Harvard Medical School with affiliate appointments in Microbiology and the Laboratory of Systems Pharmacology, and as an Associate Member of the Broad Institute. He leads the Baym Lab, which studies microbial evolutionary genomics and antibiotic resistance through a hybrid of experimental, computational, and theoretical approaches. His research focuses on: Antibiotic Resistance Evolution and practical interventions Mobile Genetic Elements (plasmids, phages, transposons) Computational Genomic Algorithms for big data analysis Synthetic Biology tools and technologies Key recent publications explore phage discovery systems , phylogenetic compression of microbial genomes, and RNA-guided gene drives in plasmids. His work is supported by multiple NIH/NIGMS and NSF grants including a MIRA award. Scientific honors include: Packard Fellowship (2018) Pew Biomedical Scholarship (2020) Sloan Research Fellowship (2020) A. Clifford Barger Excellence in Mentoring Award (2021) SSQBio Mentorship Award (2022) The lab actively trains PhD students and postdoctoral fellows with alumni occupying academic and industry positions globally. Current team members include researchers from interdisciplinary backgrounds working at the intersection of experiment, computation, and theory .

• Mechanobiology
• Ophthalmology
• Biomedical Engineering
• +۴ مورد دیگر

Darryl Overby is a Professor of Mechanobiology in the Department of Bioengineering at Imperial College London's Faculty of Engineering. His academic affiliations include the CRUK Convergence Science Centre, Cancer Technology Network, and multiple interdisciplinary networks focused on ocular biomechanics, vascular science, and regenerative medicine. He holds an Orcid identifier (0000-0001-9894-7515) and was previously affiliated with Tulane University and Harvard Medical School. Education: Ph.D. in Mechanical Engineering (2002) from MIT under Prof. Roger Kamm, followed by postdoctoral research at Harvard Medical School under Prof. Donald Ingber. His work focuses on cellular biomechanics, mechanotransduction, and the role of mechanical forces in intraocular pressure regulation and glaucoma pathophysiology. Research interests span mechanobiology of Schlemm’s canal endothelial cells, nitric oxide signaling in ocular tissues, and development of organ-on-chip models for studying aqueous humor outflow dynamics. His lab explores how mechanical signals drive transcellular pore formation and how these mechanisms fail in glaucomatous conditions. Key contributions include consensus guidelines for Brillouin microscopy measurements, ex vivo perfusion studies, and the role of TRPV4 channels in mechanosensing. His work integrates engineering techniques with clinical ophthalmology to advance therapies targeting glaucoma and ocular hypertension. Professional activities include leadership roles in the Ocular Biomechanics Network and Wound Healing and Regeneration Network. His research has led to patents for devices enhancing aqueous humor drainage and RNAi-based therapies.

Colin Sempleمشاهده پروفایل

استاد

• Cancer genomics
• Structural mutations
• Molecular evolution
• +۵ مورد دیگر

Professor Colin Semple is a leading researcher at the University of Edinburgh's Institute of Genetics and Cancer (IGC), where he serves as Group Leader and Head of Bioinformatics. His work is conducted within the MRC Human Genetics Unit, focusing on computational genomics and the analysis of structural mutations in both germline and cancer contexts. Professor Semple's research investigates the origins and impacts of structural mutations in the human genome, with particular emphasis on how these alterations affect gene function in developmental contexts and drive cancer progression. His group studies complex structural rearrangements in challenging cancer types including ovarian cancer, glioblastoma, and mesothelioma, where tumor genomes undergo dramatic reorganization. The research is guided by four key questions: What are the origins of structural mutations? How do they impact gene function? How does structural complexity drive disease progression? How do diverse mutational constellations combine to create adaptations and vulnerabilities? Analysis of Professor Semple's publications reveals a consistent focus on structural variation in cancer genomics, with particular attention to ovarian cancer mechanisms, lesion segregation in tumor evolution, and the functional consequences of genomic rearrangements. His work frequently employs whole genome sequencing approaches to uncover previously hidden layers of genomic variation that affect more of the genome than traditional short variants. Professor Semple leads a substantial research team including bioinformaticians and PhD students, and oversees the Bioinformatics Analysis Core which provides collaborative expertise to over 500 researchers at the IGC. His group maintains strong collaborations with both local researchers at the University of Edinburgh and international consortia, working closely with clinicians to translate genomic findings into potential diagnostic and therapeutic approaches. The Semple Lab is funded by major organizations including the Medical Research Council (MRC), Cancer Research UK (CRUK), and the Chief Scientist Office (CSO).

Markus Heiligمشاهده پروفایل

استاد

• Addiction Neuroscience
• Alcohol Dependence
• Neuropharmacology
• +۴ مورد دیگر

Markus Heilig is a Professor of Psychiatry and Head of the Department of Biomedical and Clinical Sciences (BKV) at Linköping University. He serves as Director of the Center for Social and Affective Neuroscience (CSAN), integrating basic and clinical neuroscience to address addictive and affective disorders. His work bridges neuropharmacology, molecular psychiatry, and clinical trials. Linköping University (Current) Center for Social and Affective Neuroscience (CSAN) (Director) Wallenberg Center for Molecular Medicine (Collaborator) His research focuses on alcohol dependence mechanisms, stress-neurotransmitter interactions (e.g., CRF, substance P, endocannabinoids), and personalized medicine approaches. Using animal models and human neuroimaging (fMRI), his lab explores epigenetic changes in frontal lobe and amygdala neurons that drive compulsive alcohol use. Recent publications highlight his work on endocannabinoid modulation for PTSD treatment, neural correlates of reward choices, and pharmacological interventions targeting GABA and opioid receptors. His studies often combine brain imaging, behavioral analysis, and pharmacology. Scientific awards include the 2019 Wallenberg Clinical Scholar grant and 2017 CAN/Nordic Drugs prizes. Heilig's research is supported by Vetenskapsrådet (SEK 57 million center funding) and international donations like the Andrew J. Bock Memorial Fund.

Betsy Foxmanمشاهده پروفایل

استاد

• Infectious Disease Epidemiology
• Human Microbiome Research
• Antibiotic Resistance
• +۵ مورد دیگر

Betsy Foxman serves as the Hunein F. and Hilda Maassab Professor of Epidemiology at the University of Michigan School of Public Health. She directs three major initiatives: the Center for Molecular and Clinical Epidemiology of Infectious Diseases, the Integrated Training in Microbial Systems program, and the Certificate in Healthcare Infection Prevention & Control. Her academic leadership spans decades with continuous research contributions. Dr. Foxman earned her PhD and MSPH from UCLA (1983, 1980) and BS from UC Berkeley (1977). Her research centers on infectious disease transmission, microbiome ecology, antibiotic resistance, and wastewater surveillance . Key projects include analyzing the oral microbiome in dental caries using genomic methods, studying nose/throat microbiome associations with respiratory infections in nursing facilities, and developing wastewater monitoring for antibiotic-resistant pathogens. Her work integrates next-generation sequencing with epidemiological analysis to identify novel interventions. Publication trends reveal consistent focus on microbiome-pathogen interactions across multiple body sites (oral, vaginal, gut, respiratory). Recent articles demonstrate methodological innovation in wastewater epidemiology (2024 Norovirus GII monitoring) and clinical applications like predicting vancomycin-resistant enterococci contamination (2023 Lancet study). Her research bridges molecular microbiology with population health, emphasizing translational potential for diagnostics and public health interventions. Fellow of the Infectious Disease Society of America Fellow of the American College of Epidemiology Fellow of the American Academy of Microbiology Dr. Foxman's advising portfolio includes numerous NIH-funded projects on microbiome dynamics and infection control. Her leadership in the Center for Molecular and Clinical Epidemiology drives collaborative research across departments. Current initiatives focus on wastewater surveillance standardization and microbiome-based diagnostics for infection prevention. She maintains active laboratories for genomic analysis of microbial communities and clinical sample processing.

• Machine Learning
• Pattern Recognition
• Classification
• +۶ مورد دیگر

Christian Igel is a Professor at the Department of Computer Science, University of Copenhagen, and serves as director of the SCIENCE AI Centre . He is also a co-lead of the Pioneer Centre for Artificial Intelligence in Denmark. His academic journey includes a Doctoral degree from Bielefeld University (2002) and a Habilitation degree from Ruhr-University Bochum (2010). Igel is a Juniorprofessor (2002–2010) and has held editorial roles at journals like KI - Künstliche Intelligenz and Artificial Intelligence Journal . Doctoral degree: Faculty of Technology, Bielefeld University, Germany (2002) Habilitation degree: Department of Electrical Engineering and Information Sciences, Ruhr-University Bochum, Germany (2010) His research spans Machine Learning , focusing on Support Vector Machines , Evolution Strategies , Reinforcement Learning , Deep Neural Networks , and PAC-Bayesian Analysis . He applies these methods to Environmental Monitoring , Medical Diagnostics , and Climate Research . Recent publications highlight work on adversarial machine learning , environmentally sustainable AI , and tree resource mapping using deep learning. His scientific awards include being a ELLIS Fellow . Igel’s software tools like Shark , woody , and Multi-Planar UNet are widely used in research and industry. Notable grants and collaborations involve projects with European Lab for Learning and Intelligent Systems (ELLIS) , SCIENCE AI Centre , and international teams in Denmark , Germany , and France . His lab leadership emphasizes open-source frameworks and reproducible research. Editorial Roles: German Journal on Artificial Intelligence , Evolutionary Computation Journal , Artificial Intelligence Journal Software Projects: Shark , woody , Multi-Planar UNet , U-Time Collaborations: SCIENCE AI Centre , Pioneer Centre for Artificial Intelligence , European Lab for Learning and Intelligent Systems

Guizhen Zhaoمشاهده پروفایل

استادیار

• Cardiovascular Diseases
• Epigenetics
• Molecular Biology
• +۶ مورد دیگر

Guizhen Zhao is an Assistant Professor at the University of Houston College of Pharmacy , Department of Pharmacological and Pharmaceutical Sciences. Her research focuses on epigenetic and molecular mechanisms in cardiovascular diseases (CVD), particularly aortic aneurysm, dissection, and atherosclerosis, with a goal to drive drug discovery innovations. Major research areas: Metaboloepigenetic properties of vascular cells, chromatin remodeling, vascular cell crosstalk Methodologies: bulk RNA-seq, single-cell RNA-seq, ChIP-seq, ATAC-seq, spatial transcriptomics, metabolomics Ongoing projects include studying BAF60c-dependent epigenetic modifications in smooth muscle cell biology, BAF60c-mediated iPSC differentiation, BAF60a in endothelial dysfunction, and vascular cell interactions in CVD development. Scientific contributions include 15+ publications on abdominal aortic aneurysm, atherosclerosis, and chromatin remodeling mechanisms, with recent work on adenosine kinase inhibition and KLF11 as therapeutic targets. 2023-25: Career Development Award, American Heart Association 2021-22: Postdoctoral Fellowship, American Heart Association 2019: Young Investigator Award, American Heart Association

• Plant Developmental Biology
• Epigenetics
• Plant Genetics
• +۵ مورد دیگر

Ueli Grossniklaus is an Ordinary Professor at the University of Zurich within the Faculty of Mathematical and Natural Sciences , affiliated with the Department of Plant and Microbiology . His work focuses on plant developmental biology, particularly epigenetic and genetic mechanisms governing reproduction and adaptation. Key Courses: Epigenetics, Plant Biology Workshop, Group Seminars on Current Research Laboratory Techniques: Advanced methods in plant cell mechanics, transcriptomics, and genome editing Research Interests span plant epigenetics, reproductive biology, and the interplay between environmental stress and genetic regulation. He investigates: Mechanistic control of gametogenesis and fertilization Epigenetic contributions to plant adaptation Evolutionary implications of asexual reproduction Biophysical forces in plant cell growth Publication Trends (2025–2018) reveal expertise in: Arabidopsis and fern model systems Epigenetic regulation (DNA methylation, histone dynamics) Apomixis and hybrid seed failure mechanisms Biomechanics of pollen tubes and carnivorous plants Genome editing tools (CRISPR) and long-read sequencing Scientific Collaborations include interdisciplinary projects on: Microfluidic devices for plant cell analysis Gene drive ecology and ethics 3D imaging of plant reproductive structures Advising and Grants focus on mentoring through research internships in developmental biology, genetics, and systems biology. His lab engages in: Epigenetic response to environmental stress Cell wall mechanics in reproduction Computational modeling of plant growth Laboratory Teams integrate plant biologists, bioengineers, and computational scientists to study: Mechanistic gene regulation Evolutionary developmental biology Microrobotics for cellular force measurement

Alexander Nikitinمشاهده پروفایل

استاد

• Cancer Biology
• Molecular Pathology
• Stem Cell Research
• +۳ مورد دیگر

Alexander Nikitin is a Professor of Pathology at Cornell University's College of Veterinary Medicine, Department of Biomedical Sciences. His research focuses on molecular mechanisms linking tissue homeostasis to cancer development using autochthonous mouse models. Key Affiliation: Cornell University, Ithaca, NY Research Niche: Cancer-prone stem cell niches in female reproductive tract and prostate Research Interests Dr. Nikitin investigates how aberrations in p53/miR-34/MET and Rb networks drive malignant transformation of adult stem cells. His work includes: Identification of ovarian surface epithelium stem cell niche Technology-oriented cross-disciplinary collaborations Characterization of cancer initiation mechanisms in reproductive tissues Article Trends His publications span 2003–2025, emphasizing: Mouse models for epithelial cancers Role of tumor suppressor genes (p53, Rb) in cancer miR-34 family's tumor suppression functions Stem cell niche mapping in reproductive tract cancers Genetic drivers of high-grade serous carcinomas Translational research applications Lab Members Current lab personnel include: Andrea Flesken-Nikitin (Assistant Research Professor) Christopher Ashe (Research Support Specialist) Technicians and student researchers

Katherine E. Varleyمشاهده پروفایل

دانشیار

• Breast Cancer
• Epigenetics
• Gene Expression Regulation
• +۵ مورد دیگر

Katherine E. Varley, PhD is a Huntsman Cancer Institute Investigator and Associate Professor in the Department of Oncological Sciences at the University of Utah. She leads the Varley Lab and is a member of the Nuclear Control of Cell Growth and Differentiation Program, focusing on breast cancer genomics, epigenetics, and biomarker discovery. Her work bridges computational biology with clinical applications to improve breast cancer diagnosis and treatment. Dr. Varley earned her BS in Biology with a concentration in Computational Biology from Cornell University in 2003, followed by a PhD in Computational Biology from Washington University School of Medicine in 2009 under Dr. Robi Mitra. Her postdoctoral training was conducted in Dr. Richard M. Myers' laboratory at the HudsonAlpha Institute for Biotechnology, where she participated in the ENCODE Project Consortium. Her research focuses on using next-generation sequencing and computational analysis to study gene expression, transcription factor binding, and DNA methylation patterns in breast cancer. The Varley Lab investigates epigenetic gene regulation, develops novel molecular methods and bioinformatics approaches, and translates discoveries into clinical tools. Key research areas include Clinical Trial Genomics, Epigenome Engineering, Detecting Circulating Tumor DNA, and identifying Transcription Factors Driving Metastasis, with particular emphasis on triple-negative breast cancer. Analysis of Dr. Varley's publications reveals a consistent trajectory from fundamental genomic mechanisms to clinical translation, with recent work emphasizing biomarker discovery, tumor heterogeneity, and the development of genomic tools for precision oncology. Her research spans cancer biology, genomics, and computational analysis to address critical challenges in breast cancer treatment. Dr. Varley holds multiple patents related to cancer diagnostics and genomic technologies, including targeted sequencing methods, multigene assays for recurrence risk, and biomarkers for triple-negative breast cancer. These inventions reflect her commitment to translating basic research into clinical applications. She actively collaborates with clinical investigators in breast cancer trials and works closely with the Breast and Gynecologic Cancers Disease Center at Huntsman Cancer Institute. Her lab maintains four main research thrusts that collectively address breast cancer from molecular mechanisms to clinical applications, demonstrating a comprehensive approach to improving patient outcomes through genomic technologies.

Johanna Kowalkoمشاهده پروفایل

دانشیار

• Evolutionary Biology
• Behavioral Genetics
• Neural Development
• +۳ مورد دیگر

Johanna Kowalko serves as an Associate Professor in the Department of Biological Sciences at Lehigh University, where she maintains an active research program focused on evolutionary and behavioral genetics. Her laboratory investigates the genetic and neural mechanisms underlying behavioral diversity using Astyanax mexicanus (blind cavefish) as a model system. The cavefish model provides unique opportunities to study convergent evolution through independently colonized cave populations. Her primary research interests center on four interconnected themes: (1) How natural genetic variation alters developmental processes to produce phenotypic change, particularly eye regression in cavefish; (2) The role of pleiotropy in behavioral evolution, especially the relationship between albinism and sleep loss; (3) The evolution of behavioral plasticity in response to environmental conditions like nutrient availability; and (4) Evolutionary approaches to identify genetic architecture regulating social behavior, comparing highly social surface fish with cave-adapted populations showing reduced social behaviors. Her work bridges developmental biology, neuroscience, and evolutionary genetics to understand how behaviors evolve. Dr. Kowalko's recent publications demonstrate significant contributions to understanding convergent evolution of cave adaptations, with particular emphasis on sleep regulation, circadian rhythms, and sensory system modifications. Her research has revealed how the oca2 gene pleiotropically influences both albinism and sleep loss in cavefish populations. Her scientific recognition includes being featured as an In the Spotlight – Early Career Researcher in the Journal of Experimental Zoology B. She has contributed to major collaborative efforts including the chromosome-level genome assembly of Astyanax mexicanus . Dr. Kowalko actively develops genetic and experimental methodologies for cavefish research, including CRISPR-based genome editing techniques. Her laboratory examines both laboratory and wild populations to understand the environmental contexts driving evolutionary changes in behavior and morphology. Current field research focuses on defining sleep, feeding, and social behaviors in natural cave environments to identify selective pressures shaping these adaptations.

Nikolaus Rajewskyمشاهده پروفایل

استاد

• RNA Biology
• Gene Regulation
• Single-Cell Transcriptomics
• +۶ مورد دیگر

Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.