جستجوی استاد راهنمای دانشگاهی

Edor Kabashiمشاهده پروفایل

پژوهشگر

• Neurological Disorders
• Neurodevelopmental Diseases
• Neurodegenerative Diseases
• +۵ مورد دیگر

Edor Kabashi is a leading researcher in translational neuroscience, specializing in genetic causes of neurological disorders such as Developmental and Epileptic Encephalopathy (DEE), Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD). His team at the Imagine Institute (Necker Hospital site) develops advanced cellular and zebrafish models to elucidate disease mechanisms and accelerate therapeutic validation. Key research areas include iPSC-derived neurons, drug screening platforms, and genomic sequencing analysis. Collaborations span national/international networks with institutions like ANR and pharmaceutical partners. Expertise: Genetic epilepsy, neurodegeneration, translational drug development Techniques: CRISPR gene editing, induced pluripotent stem cells, high-throughput screening Current projects focus on fast-tracking neuroprotective compounds into clinical trials, leveraging state-of-the-art platforms such as transcriptomic/proteomic analysis and advanced imaging. Actively recruiting postdocs and PhD candidates with expertise in zebrafish models, molecular genetics, and bioinformatics.

Hector Carunchoمشاهده پروفایل

استاد

• Neurobiology
• Depression
• Schizophrenia
• +۳ مورد دیگر

Hector Caruncho is Professor and Canada Research Chair in Translational Neuroscience at the University of Victoria's Division of Medical Sciences, with adjunct appointments at University of British Columbia and University of Saskatchewan. He holds a PhD in Cell Biology from University of Santiago de Compostela and completed postdoctoral training at NIH and Georgetown University. Research focuses on: Neurobiological mechanisms of depression/schizophrenia Biomarker discovery for mood disorders Neuroinflammation pathways Reelin signaling therapeutics Recent publications explore gut-brain axis interactions, microglia-targeted therapies, and epigenetic regulation in stress models. Awards include Canada Research Chair and Fulbright Scholarship. Outreach activities include engagement with patient associations.

• Auditory Neuroscience
• Neurophysiology
• Sensory Processing
• +۴ مورد دیگر

Dr. Jack Kelly is a Distinguished Research Professor (Retired) in the Neuroscience department at Carleton University, holding a Ph.D. from Vanderbilt University. His research focuses on central nervous system mechanisms underlying hearing and auditory information processing, particularly neural structures in the auditory brainstem and forebrain involved in sound perception and spatial localization. Key projects investigate the superior olivary complex, lateral lemniscus, and auditory cortex, employing neurophysiological, neuroanatomical, and behavioral techniques. He has contributed extensively to understanding auditory processing through studies on synaptic receptors (AMPA, NMDA, GABAA), ion channels (potassium), and neural circuits in the inferior colliculus and dorsal nucleus of the lateral lemniscus. His work addresses the neural basis of complex sound perception, such as speech and animal vocalizations, and the origins of central auditory processing disorders. Not eligible to supervise students, Dr. Kelly’s research has been published in journals like Journal of Neuroscience , Neurophysiology , and Hearing Research . His publications span 1996–2005, emphasizing auditory pathway modulation, synaptic mechanisms, and sound localization. Despite no listed awards, his contributions to auditory neuroscience are significant. His lab is located in the Health Sciences Building at Carleton University.

Jinwoo Parkمشاهده پروفایل

دانشیار

• Behavioral pharmacology
• Metabolism
• Neurobiology
• +۵ مورد دیگر

Jinwoo Park is an Associate Professor at the Department of Biotechnical and Clinical Laboratory Sciences within the Jacobs School of Medicine & Biomedical Sciences at the University at Buffalo . His research focuses on understanding the role of catecholamines (dopamine, norepinephrine) in stress- and reward-related behaviors, and their dysfunction in disorders like substance abuse and neurodegenerative diseases . Education: PhD in Chemistry (Electrochemistry), Michigan State University (2006) Fellowship in Neurochemistry/Electrochemistry, University of North Carolina at Chapel Hill (2011) His work develops electrochemistry-based sensors for real-time neurochemical monitoring, particularly in the limbic system . Key areas include neurotransmission dynamics in drug addiction , stress responses , and metabolic regulation . He has secured significant grants from NIH/NIDA and NIDDK , including a $3.7M NIH/NIDA grant (2025–2030) to study sex differences in reward circuits . Recent publications highlight advancements in fast-scan cyclic voltammetry (FSCV) for heterogeneous dopamine signaling in the olfactory tubercle and nucleus accumbens , with applications to methamphetamine and nicotine addiction . He also explores amylin signaling in macronutrient intake and urotensin II modulation of cocaine effects. Scientific Awards Whitehall Foundation Grant (2017) Irwin Kopin Traveling Fellowship (2012) NIDA Travel Stipend (2010) Invited speaker at SFN Nanosymposium (2010) Gordon Research Seminar Travel Stipend (2009) He serves as a Principal Investigator on multiple NIH-funded projects and mentors trainees through roles like Director of the Biotechnology Undergraduate Program (2020–present). His lab employs cutting-edge techniques like optogenetics and flexible microelectrode arrays to map neurochemical pathways in addiction and neurodegeneration .

Greg Scherrerمشاهده پروفایل

دانشیار

• Pain Neurobiology
• Opioid Receptor Function
• Neural Circuits
• +۶ مورد دیگر

Greg Scherrer, PhD is an Associate Professor at the University of North Carolina at Chapel Hill , holding appointments in the Cell Biology & Physiology and Pharmacology departments. As a member of the UNC Neuroscience Center , his research focuses on the neurobiological mechanisms underlying pain perception and opioid action. Research Interests: Elucidating genetic, molecular, and circuit-level mechanisms of pain experience Investigating opioid receptor localization, trafficking, and signaling to dissociate analgesia from side effects Developing mouse models to study endogenous opioid systems Addressing the opioid epidemic through novel non-addictive drug targets Recent Research Trends: His work spans opioid receptor dynamics in neural circuits, microglial-neuronal interactions in pain, and chemogenetic approaches to peripheral drug action. Publications highlight the role of delta and mu opioid receptors in pain pathways, placebo pain relief mechanisms, and neuroimmune contributions to chronic pain. Lab Affiliation: The Scherrer Lab employs interdisciplinary techniques including mouse genetics, in vivo imaging, and computational modeling to advance pain therapeutics.

• Proteomics
• Metabolomics
• Plant-Microbe Interactions
• +۳ مورد دیگر

Prof. Dr. Karsten Niehaus serves as Head of the Proteome and Metabolome Research Group at the Center for Biotechnology (CeBiTec) and Faculty of Biology, University of Bielefeld. His research focuses on proteomics and metabolomics applications in plant-microbe interactions, bacterial stress responses, and disease model systems. His laboratory employs advanced mass spectrometry imaging and cell phenotyping technologies to investigate molecular responses in crops like sugar beet and grapevines under abiotic stress conditions, as well as in cancer models where differentiation therapy impacts tumor malignancy. The group also explores microbial biotechnology through Xanthomonas campestris studies on xanthan production and stress adaptation. Selected publications highlight innovations in 3D microfluidics for biomarker detection and bioinformatics platforms like MetHoS for metabolomics data analysis. His work appears in journals covering Frontiers in Plant Science , Scientific Reports , and Journal of Experimental Botany . Contact: kniehaus@cebitec.uni-bielefeld.de | Office: UHG W7-117

Paul Millerمشاهده پروفایل

پژوهشگر

• Molecular Pharmacology
• Structural Biology
• Neuropharmacology
• +۷ مورد دیگر

Paul Miller is a researcher in the Department of Pharmacology at the University of Cambridge, part of the School of Biological Sciences. His work focuses on the structural and molecular pharmacology of ligand-gated ion channels, particularly GABAA and glycine receptors, with a strong emphasis on allosteric modulation and receptor activation mechanisms. His research interests lie at the intersection of structural biology, neuropharmacology, and molecular biophysics. He investigates how neurosteroids, zinc, and other modulators influence receptor function, using structural and biochemical approaches to uncover mechanisms of drug action. His work contributes to understanding inhibitory neurotransmission and developing targeted CNS therapeutics. The publication record shows a consistent focus on Cys-loop receptors, especially GABA and glycine receptors, with recent work advancing structural insights into receptor activation and drug selectivity. Themes include receptor subtype specificity, allosteric modulation, metal ion effects, and high-resolution structural determination via cryo-EM and crystallography. While no formal awards are listed in the provided text, his contributions to the field are evident through high-impact publications in structural pharmacology. Paul Miller advises postgraduate researchers and contributes to the academic mission of the Department of Pharmacology. His work is supported by research grants in molecular neuroscience and structural pharmacology, though specific funding sources are not detailed. He is an active member of the department’s research and postgraduate education committees. He is involved in research groups focusing on receptor biology and the Naked Mole-Rat Initiative, contributing to innovative models in pharmacological research.

Russell Carrمشاهده پروفایل

استاد

• Toxicology
• Neurotoxicology
• Environmental Health
• +۳ مورد دیگر

Russell Carr , PhD, is a Professor at Mississippi State University's College of Veterinary Medicine. Holding a PhD in Animal Physiology (MSU, 1994) and MS in Biological Sciences (MSU, 1990), he focuses on neurotoxicology, pesticide mechanisms, and endocannabinoid system interactions. His career spans 30+ years studying organophosphate effects on neurotransmitter systems across developmental stages. Key Research Areas: Organophosphate pesticide neurotoxicity Endocannabinoid system disruption Developmental neurochemical impacts Cross-species enzyme inhibition Recent Publications (2023-2021) reveal trends in nanochannel CBD delivery systems, chlorpyrifos-induced proteomic changes in amygdala, and multi-omics approaches to pesticide-immune interactions. Earlier works establish foundational knowledge on cholinesterase inhibition kinetics and age-dependent toxicity profiles. Notable Contributions: Elucidated mechanisms of endocannabinoid enzyme inhibition by pesticides, demonstrated neurochemical impacts of low-dose exposures, and developed comparative models across species (rodents, fish).

Igor Spigelmanمشاهده پروفایل

استاد

• Neuroscience
• Neurophysiology
• Alcohol Research
• +۷ مورد دیگر

Igor Spigelman is a Professor in the Dentistry Department at the University of California Los Angeles (UCLA), with a robust research program spanning neuroscience, alcohol effects on the brain, pain mechanisms, and cannabinoid pharmacology. His work bridges dental and medical neuroscience, focusing on the neural mechanisms underlying pain, addiction, and stress responses. Spigelman's research interests primarily center on neurophysiological mechanisms of pain and addiction. His laboratory investigates GABAergic neurotransmission, trigeminal system function, and the molecular basis of alcohol dependence. He has made significant contributions to understanding how chronic alcohol exposure alters neuronal function in brain regions involved in stress response and reward processing. His work on peripheral cannabinoid receptors has implications for developing novel pain therapeutics without central side effects. Recent research has expanded into AI applications for neurodegenerative disease biomarker discovery, particularly for ALS. Analysis of his publication record reveals consistent research themes across three decades: the neurobiology of alcohol dependence, trigeminal pain pathways, and GABA receptor plasticity. His most cited work focuses on ethanol-induced changes in GABA receptor function and the role of peripheral cannabinoid receptors in pain management. The research demonstrates strong translational potential, with several publications exploring therapeutic approaches for alcohol use disorders and chronic pain conditions. Spigelman's laboratory has maintained active collaborations across multiple institutions, with frequent co-authorship with researchers from UCLA's neuroscience, psychology, and medical departments. His work shows consistent funding support as evidenced by the sustained publication record and involvement in NIH T32 training grants mentioned in the departmental information.

Marjorie C. Gondre-Lewisمشاهده پروفایل

استاد

• Neuroscience
• Addiction
• Brain Reward Pathways
• +۷ مورد دیگر

Marjorie C. Gondre-Lewis, Ph.D. is a tenured Professor of Neuroscience at the Howard University College of Medicine , where she also serves as Associate Dean for Faculty Development and Chief Justice, Equity, Diversity, and Inclusion (JEDI) Officer . Her research focuses on Precision Brain Health approaches for underserved communities, particularly addressing addiction mechanisms, early life stress, and health disparities. Education: B.A. in French Civilization/Chemistry, New York University (1990) M.S. in Cellular and Molecular Neuroscience, Albert Einstein College of Medicine (1998) Ph.D. in Neuroscience, Albert Einstein College of Medicine (2002) Postdoctoral Fellow, NICHD/NIH (2005) Research Interests: Neuroscience Addiction and Substance Use Disorders Brain Reward Pathways (nicotine, alcohol, opioids) Early Life Stress and Toxic Stress Effects Health Disparities and Social Determinants Precision Medicine for Underserved Populations Grants & Funding: NIH/NICHD (U54 HD090257) NIH/NIMHD (R41 MD012318, G12MD007595) VA/CSRD (I01 CX000479) NIH (R01HD70888) University New York Research Foundation (Q0942016) Leadership: Director of the Developmental NeuroPsychoPharmacology Laboratory Mentor at all career stages

• Ion Channels
• Neuroscience
• Glial Physiology
• +۳ مورد دیگر

Laura Bianchi, Ph.D., is a Professor of Physiology and Biophysics with expertise in ion channel biology and sensory neuroscience. Her research focuses on glial-neuronal interactions, particularly the role of ion channels and transporters in modulating synaptic function and behavior using C. elegans as a model organism. Key interests include DEG/ENaC channels in sensory perception and neurotoxicity, and the molecular mechanisms underlying glial contributions to nervous system function. Education: She holds a PhD in Physiology from the University of Florence (1997) and a BS in Biochemistry from the University of Milan (1992). Research Highlights: Bianchi's lab investigates glial ion channel regulation of GABA release, calcium-mediated neurotoxicity in DEG/ENaC dysfunction, and the discovery of novel glial-enriched channels. Recent work includes identifying an ER anion channel and developing protocols for imaging calcium in glia. Notable Awards: U-Choose SEEDS Award (2024), FASI Award (2024) Labs/Teams: Active in collaborative research on mechanosensation and neurodegeneration, with a lab website at laura-bianchi.com .

David Hallidayمشاهده پروفایل

استاد

• Computational Neuroscience
• Neural Computing
• Intelligent Systems
• +۳ مورد دیگر

Professor David Halliday holds a position at the University of York as a Professor and Chair of the Research Committee. His research focuses on interdisciplinary fields of Computational Neuroscience and Neural Computing, with a particular emphasis on neural networks and neurophysiological signal analysis. He leads the Intelligent Systems and Nano-science Group and maintains an active research profile with over 100 publications. His work integrates theoretical modeling with experimental techniques to investigate topics such as motor control, neural oscillations, and clinical applications of machine learning. David Halliday's academic training includes a BSc and PhD, though specific institutions are not detailed in the provided text. His research interests span computational modeling of neural circuits, development of neuro-inspired algorithms, and application of signal processing techniques to neurological disorders. His homepage at http://www-users.york.ac.uk/~dh20 provides further details, including access to his ResearcherID profile (RID: A-3848-2009). Key research contributions include studies on cortico-muscular coherence in movement disorders, astrocyte-neuron interactions, and fault-tolerant spiking neural networks. His publications demonstrate interdisciplinary collaboration across computational neuroscience, biomedical engineering, and clinical diagnostics. Notably, his work combines experimental neurophysiology with advanced computational methods, such as non-parametric directionality analysis and wavelet-based coherence estimation. Recent studies have addressed clinically relevant topics like gait disturbance in spinal cord injury and biomarker identification in bladder cancer using machine learning approaches.

• Synaptic Transmission
• Neuroscience
• Glutamate Receptors
• +۳ مورد دیگر

Susumu Tomita is a Professor of Cellular & Molecular Physiology and Neuroscience at Yale School of Medicine, with fully joint appointments in both departments. He holds affiliations with the Yale Combined Program in the Biological and Biomedical Sciences (BBS), Kavli Institute for Neuroscience, and Interdepartmental Neuroscience Program. His research focuses on understanding synaptic transmission and plasticity mechanisms, particularly involving glutamate receptors and their regulatory proteins. Tomita received his PhD from the University of Tokyo (2000) and completed postdoctoral training at UCSF (2005). His laboratory investigates how glutamate receptor trafficking and properties are modulated to support learning, memory, and cognition. Key findings include discovery of TARP proteins' roles in AMPA receptor regulation and mechanisms underlying synaptic plasticity. Notable awards include the Alfred P. Sloan Research Fellowship (2007), NARSAD Young Investigator Award (2007), and Klingenstein Fellowship (2006). He collaborates with researchers like Marina Picciotto, Michael Higley, and Yann Mineur on projects spanning neurotransmitter receptor biology and circuit neuroscience. His recent articles advance understanding of nicotinic acetylcholine receptors in habenula circuits, kainate receptor roles in immune defense, and chemogenetic modulation of synaptic proteins. Tomita's work bridges molecular mechanisms with systems-level neural circuit function, contributing to both basic neuroscience and potential therapeutic strategies for neurological disorders.

Uwe Rudolphمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Cognitive Function
• +۳ مورد دیگر

Uwe Rudolph serves as Professor and Head of the Department of Comparative Biosciences within the College of Liberal Arts & Sciences at the University of Illinois Urbana-Champaign. He holds an affiliate appointment at the Carl R. Woese Institute for Genomic Biology. His research centers on the neurobiology of cognitive function in aging and the pathophysiology of neuropsychiatric disorders, with specialized focus on GABA and NMDA receptor mechanisms. Current investigations examine receptor-mediated cognitive impairment, genetic contributions to psychosis, and neuroinflammatory processes in pulmonary disease. Recent publications (2023-2025) reveal interdisciplinary work spanning molecular neuroscience, immunology, and veterinary medicine. Key trends include receptor pharmacology applications in depression treatment, genetic models of cognitive disorders, and translational approaches to animal welfare. His work consistently addresses receptor dysfunction in neuropsychiatric conditions while expanding into novel therapeutic domains.

Jefferson W. Kinneyمشاهده پروفایل

استاد

• Alzheimer's disease
• Neurodegenerative disorders
• Cellular and molecular mechanisms
• +۵ مورد دیگر

Jefferson W. Kinney is a Professor and Founding Chair of the Department of Brain Health at the Kirk Kerkorian School of Medicine, University of Nevada Las Vegas (UNLV) . He co-directs both the Pam Quirk Brain Health and Biomarker Laboratory and the Translational Mechanisms and Drug Discovery Laboratory , focusing on neurodegenerative diseases. Colorado State University - PhD National Institute of Mental Health - Intramural Research Training Fellowship The Scripps Research Institute - Helen Dorris Fellowship Dr. Kinney's research spans cellular and molecular mechanisms of Alzheimer's disease , with emphasis on: Neuronal-glial interactions in AD pathogenesis Role of GABA B receptors in memory deficits Diabetes-induced AD risk (insulin signaling, hyperglycemia) Neuroinflammatory pathways in AD and traumatic brain injury (TBI) Translational biomarker discovery in clinical samples GPCR signaling in microglial activation His publications reveal a focus on GABAergic dysfunction , metabolic comorbidities , and translational models bridging preclinical and clinical AD research. Key techniques include: Transgenic mouse models (APP/PS1) Cellular/molecular biology (qRT-PCR, Western blot) Behavioral assays (Barnes maze, fear conditioning) Immortalized microglia cultures (BV2 cells) Scientific Honors: Reg Grundy and Joy Chambers-Grundy Chair for Brain Health Helen Dorris Fellowship in Neuropharmacology NIMH Intramural Research Training Fellowship Dr. Kinney leads two interconnected laboratories that synergize preclinical mechanisms ( Translational Mechanisms and Drug Discovery Laboratory ) with clinical biomarker discovery ( Pam Quirk Brain Health and Biomarker Laboratory ).