جستجوی استاد راهنمای دانشگاهی

Didier Trono is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL), where he leads the Laboratory of Virology and Genetics (LVG) within the School of Life Sciences. Formerly, from 2004 to 2012, he served as the founding dean of EPFL's Faculty of Life Sciences, orchestrating its development and growth during this formative period. Trono received his medical education at the University of Geneva, followed by clinical training in pathology, internal medicine, and infectious diseases in Geneva and at Massachusetts General Hospital in Boston. His scientific career began at the Whitehead Institute of MIT, and in 1990 he was recruited by the Salk Institute of San Diego to launch an AIDS research center. After seven years in the United States, he returned to Europe and eventually joined EPFL. Dr. Trono's research has evolved significantly over his career. Initially focusing on virus-host interactions, he studied pathogens like HIV and Hepatitis B virus, creating HIV-derived genetic transfer tools that are now successfully used in gene therapy. For approximately the last fifteen years, his research has centered on epigenetics, particularly exploring the impact of retroelements and their control mechanisms on development and physiology of higher organisms, including humans. His laboratory investigates how transposable elements and KRAB zinc finger proteins regulate gene expression, with important implications for understanding cancer biology and developing new diagnostic and therapeutic approaches. Analysis of his recent publications (2022-2024) reveals a strong focus on transposable elements, KRAB zinc finger proteins, and their roles in gene regulation and cancer. His work combines molecular biology, genomics, and bioinformatics approaches to understand how these ancient viral remnants have been co-opted by the host genome to regulate development and cellular functions. The research spans basic molecular mechanisms to potential clinical applications in cancer diagnosis and therapy, with some recent work also addressing SARS-CoV-2 and immune responses. Throughout his career, Professor Trono has mentored numerous PhD students, including Bojkowska Karolina, Brandão Sanches Vong Martins Filipe Amândio, Bulliard Yannick, Coluccio Andrea, Corsinotti Andrea, Coudray Alexandre, De Tribolet-Hardy Jonas Caspar, and Dorschel Iris Arianna. His laboratory has received significant funding to support research at the intersection of virology, genetics, and epigenetics, contributing to EPFL's reputation as a leading institution in life sciences research. The Trono Laboratory continues to be at the forefront of research on retroelements and their regulatory mechanisms, maintaining a vibrant research environment that bridges fundamental biological questions with potential medical applications, particularly in cancer research and precision medicine.

• Epigenetics
• Retroelements
• Transposable elements
• +۵ مورد دیگر

Hang Lu is a Professor and holds the Cecil J. "Pete" Silas Chair of Chemical & Biomolecular Engineering at the Georgia Institute of Technology. Dr. Lu also holds a Love Family Professorship and leads the Lµ Fluidics Group, which focuses on engineering microfluidic systems and machine learning tools to address complex questions in neuroscience, developmental biology, and cell biology that are difficult to address with conventional techniques. Dr. Lu's research lies at the intersection of engineering and biology, with primary interests including: Microfluidic systems for high-throughput screens and image-based genetics and genomics Systems biology: large-scale experimentation and data mining Microtechnologies for optical stimulation and optical recording Big data, machine vision, and automation Developmental neurobiology, behavioral neurobiology, and systems neuroscience Cancer biology, immunology, embryonic development, and stem cells Her laboratory engineers microfluidic devices and BioMEMS to study neuroscience, genetics, cancer biology, and biotechnology. These miniaturized Lab-on-a-chip tools operate at scales comparable to biological systems, leveraging unique micro and nano-scale phenomena to gather large-scale quantitative data about complex biological systems. Current projects include Microfluidics for Life Sciences, Optical Neuron Recordings and Manipulations, Machine Learning Tools for Neuroscience, Measuring and Modeling Behavior, and High-throughput, High-content Cell-based Assays. Analysis of Dr. Lu's recent publications (2024-2025) reveals a strong trend toward integrating microfluidics with advanced computational methods: Development of deep learning frameworks for biological image analysis Advanced neuron tracking and functional imaging techniques Non-invasive characterization of 3D organoid cultures Sophisticated neuromechanical modeling of locomotion Microfluidic temperature control systems for in vivo studies Label-free imaging pipelines for neural development Dr. Lu's significant professional honors include: Cecil J. "Pete" Silas Chair of Chemical & Biomolecular Engineering Love Family Professorship The Lµ Fluidics Group actively mentors students and postdocs, currently accepting new postdoctoral researchers. The lab receives substantial funding for interdisciplinary projects at the engineering-biology interface, with research implications spanning fundamental biological understanding to therapeutic development. The group operates within Georgia Tech's School of Chemical & Biomolecular Engineering, with specialized facilities for microfluidic device fabrication, biological experimentation, and advanced imaging, maintaining strong collaborative ties across engineering, neuroscience, and biological disciplines.

• Microfluidics
• Systems Biology
• Neuroscience
• +۶ مورد دیگر

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

• Genomics
• Machine Learning
• Computational Biology
• +۳ مورد دیگر

Dawn Y. Sumner is a Professor in the Department of Earth and Planetary Sciences at the University of California, Davis. Her research focuses on geobiology, paleobiology, and planetary science, particularly reconstructing ancient environments on Earth and Mars. She is a key member of NASA’s Mars Science Laboratory team, contributing to the Curiosity rover’s exploration of Gale Crater on Mars. Sumner’s work integrates field studies, lab analyses, and interdisciplinary approaches to understand microbial life’s role in shaping Earth’s history and potential habitability on other planets. Education: Ph.D., Massachusetts Institute of Technology (1995). Research interests include microbialite formation, Antarctic lake ecosystems, and the evolution of oxygenic photosynthesis. She investigates modern microbial communities in ice-covered lakes (e.g., Lake Vanda) to understand ancient environments and their biosignatures. Her scientific awards include the California Academy of Sciences Academy Fellow (2020) and Geological Society of America Fellow (2014). Sumner emphasizes inclusive education and supports student success in STEM through feminist research practices. Labs/Teams: W.M. Keck Center for Active Visualization in the Earth Sciences (KeckCAVES), Antarctic Lake Research Group.

• Geobiology
• Paleobiology
• Geochemistry
• +۳ مورد دیگر

Hyunghoon Cho is an Assistant Professor at Yale School of Medicine in the Department of Biomedical Informatics & Data Science, with a secondary appointment in the Department of Computer Science. He received his PhD in Electrical Engineering and Computer Science from MIT (2019) and MS/BS in Computer Science from Stanford University (2013). His research focuses on computational challenges in biomedical data privacy, single-cell genomics, and network biology. Assistant Professor (Primary): Biomedical Informatics & Data Science Assistant Professor (Secondary): Computer Science Appointments: Yale School of Medicine | Broad Institute (Schmidt Fellow) Research Themes: Privacy-Enhancing Technologies for genomic and health data Scalable AI/ML tools for omics data analysis Structured biological modeling for system-level discovery His work includes secure GWAS, transcriptomic privacy assessment, and sfkit - a federated genomic analysis toolkit. He received the NIH Director's Early Independence Award and leads NSF-funded projects on confidential genome analytics. Awards: NIH Director's Early Independence Award Lab Members: Haris Smajlović (Postdoc), Vincent Angelo (CBB MS), Denis Loginov (Senior Software Engineer), Lucy Zheng (CBB PhD)

• Biomedical Data Privacy
• Genomics
• Machine Learning
• +۳ مورد دیگر

Karoline Faust is an Associate Professor at KU Leuven, affiliated with the Laboratory of Molecular Bacteriology (Rega Institute) and the Faculty of Medicine . She contributes to the iSi Health and Leuven One Health institutes, and serves on senior academic councils. Her research spans microbial systems biology, focusing on community dynamics and network analysis. Education: PhD in bioinformatics (2010, KU Leuven) Affiliations: KU Leuven, ISME Journal editorial board, Belgian Society for Microbiology Her research investigates microbial community dynamics , systems biology approaches to microbiomes, and bioinformatics tool development . She specializes in modeling human gut microbiota , synthetic microbial communities , and environmental microbiomes (e.g., microplastic impacts on Daphnia microbiomes). Her work integrates metabolic modeling , network analysis , and experimental systems to understand microbial interactions. Recent publications highlight her contributions to microbial network inference , 16S rRNA sequencing protocols , microfluidics , and ecological modeling of microbiomes. She develops tools like manta , miaSim , and CoNet to analyze community structures. Teaching: Karoline co-teaches courses in microbiology, bioinformatics, and network analysis at KU Leuven, and has contributed to international workshops on microbial network inference. Scientific Engagement: She serves as Senior Editor at ISME Journal and Secretary of the Belgian Society for Microbiology .

• Microbial community dynamics
• Microbial systems biology
• Bioinformatics
• +۶ مورد دیگر

Pengtao Xie is an Associate Professor (with tenure as of June 2025) in the Department of Electrical and Computer Engineering at the University of California San Diego. He also serves as Associate Adjunct Professor in the Division of Biomedical Informatics, Department of Medicine, and holds affiliate appointments with the Halıcıoğlu Data Science Institute, School of Biological Sciences, Shu Chien-Gene Lay Department of Bioengineering, Skaggs School of Pharmacy and Pharmaceutical Sciences, and multiple research institutes including the AI Group, Center for Machine-Intelligence, Computing and Security, Institute of Engineering in Medicine, and Institute for Genomic Medicine. Education: PhD in Machine Learning, School of Computer Science, Carnegie Mellon University Research Interests: His research focuses on machine learning inspired by human learning skills, such as self-explanation, small-group learning, and learning by teaching. He applies these techniques to large language models, foundation models, healthcare, and biomedicine. His work spans generative AI, medical imaging, protein modeling, and drug discovery. Recent Research Trends: His 2024–2025 publications emphasize generative AI for ultra-low-data medical image segmentation, multimodal large language models for biomedical applications, protein function prediction, and novel training strategies like task-adaptive pretraining and bi-level optimization for model adaptation. Scientific Awards: NIH MIRA Award (2025) NSF CAREER Award (2024) Best Graduate Teacher Award – UCSD ECE (2023) ICLR Notable-Top-5% Paper (2023) Global Top-100 Chinese Young Scholars in AI (2022) UCSD Faculty Career Development Award (2022) Tencent Faculty Award (2021) Outstanding Reviewer – ICLR (2021) AMIA Doctoral Dissertation Award Finalist (2020) Amazon AWS Research Award (2020) Tencent AI-Lab Faculty Award (2020) Innovator Award – Pittsburgh Business Times (2018) Siebel Scholarship (2014) Advising and Grants: He currently advises PhD students, postdocs, and master’s students. He has received major grants including the NIH MIRA and NSF CAREER awards, and actively mentors Schmidt AI in Science postdocs and graduate students. Teaching and Labs: He teaches ECE285 Deep Generative Models and ECE175B Probabilistic Reasoning and Graphical Models . His lab focuses on foundational and translational AI research with applications in biomedicine and healthcare.

• Machine Learning
• Artificial Intelligence
• Large Language Models
• +۷ مورد دیگر

Mona Singh is a Professor of Computer Science at Princeton University, with affiliations to the Lewis-Sigler Institute for Integrative Genomics and the Department of Molecular Biology. She has been a faculty member since 1999. Ph.D., Massachusetts Institute of Technology, 1995 A.B. and S.M. degrees in Computer Science from Harvard University Her research focuses on computational molecular biology, integrating machine learning and algorithms to analyze biological networks, protein interactions, and mutational impacts. Key areas include DNA/RNA binding prediction, protein structure analysis, and network-based disease gene discovery. Her recent work highlights trends in protein language models, kinase-substrate prediction, and equitable MHC binding algorithms. These span sub-fields like structural bioinformatics, network biology, and functional genomics. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE) Rheinstein Junior Faculty Award ACM Fellow (2019) ISCB Fellow (2018) She has taught an introductory computational biology course with Professor Coleen Murphy, covering sequence analysis, phylogenetics, and network reconstruction. Her group has developed tools like dPUC , nCOP , and DiffMut . Her lab collaborates with institutions including Carnegie Mellon, Duke University, and the Broad Institute, advancing applications in cancer genomics, metabolic disease, and precision medicine.

• Computational Biology
• Machine Learning
• Algorithms
• +۳ مورد دیگر

Lucas Paoli is a Researcher and Course Instructor at École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. He leads the Paoli Lab (Microbiome Immunity and Ecology) within the Global Health Institute (GHI) under the School of Life Sciences (SV). His roles include scientific collaboration and teaching responsibilities in life sciences engineering. Paoli holds a PhD in Microbiome Research from ETH Zürich (2018-2023), an M.Phil. in Environmental Policy from the University of Cambridge (2017-2018), and an M.Sc. in Ecology and Evolution from École normale supérieure (2015-2017). Research Focus: His work bridges microbial immunity and ecology, investigating how microbes defend against viral infections across ecosystems like oceans and human microbiomes. Techniques include global-scale metagenomics and functional genomics to study immune strategies and ecological interactions. Key themes involve microbial community dynamics, viral defense mechanisms, and the impact of environmental factors on microbial immunity. Lab & Education: The Paoli Lab explores microbiome-immunity interactions with a focus on ecological contexts. Paoli supervises PhD students in Life Sciences Engineering. His research outputs span microbial ecology, metagenomic tool development, and marine microbiome studies. Contact: lucas.paoli@epfl.ch, AAB 1 39, +41 21 693 16 99.

• Microbiome Research
• Microbial Immunity
• Ecological Genomics
• +۴ مورد دیگر

Konstantinos Kalogeropoulos is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark (DTU), leading research at the Cell Diversity Lab. His work bridges proteomics, computational biology, and snake venom research. Current projects: "The Proteomic Landscape during Influenza Infection" (2022-2025) Supervisor for PhD projects on protease network rewiring in psoriasis and wound exudate degradomics Research interests include: Proteomic analysis of inflammatory diseases Snake venom toxin structure prediction Extracellular matrix biomechanics De novo peptide sequencing algorithms Computational modeling of protease networks Recent article trends demonstrate his work in • Database-free proteomics (InstaNovo/InstaNexus) • Snake venom pathophysiology (V-ToCs clustering) • Inflammatory disease biomarkers (psoriasis, impaired healing) • Extracellular matrix mechanics (fibronectin tension, gut inflammation) Advising: Supervises PhD students Polhaus, C. J. M. and Haack, A. M., focusing on protease networks and wound healing.

• Proteomics
• Snake Venom Research
• Protein Structure Prediction
• +۳ مورد دیگر

Dr. Gabriele Schweikert is a Senior Lecturer and Principal Investigator with a joint appointment between the Division of Computational Biology in the School of Life Sciences at University of Dundee and Cyber Valley in Tuebingen. Her research focuses on applying machine learning techniques to understand epigenetic mechanisms and molecular processes in living cells. Dr. Schweikert completed her PhD at the Max Planck Institute Tuebingen working with Schoelkopf, Weigel, and Raetsch labs on machine learning for computational gene finding. She subsequently joined Adrian Bird's lab at the Wellcome Trust Center for Cell Biology in Edinburgh, a pioneer in epigenomic research. Prior to her current position, she held prestigious Marie Curie and EMBO Fellowships at the School of Informatics, University of Edinburgh. Her research interests center on using machine learning to decode epigenetic mechanisms that determine cellular identity and function. She investigates how cells with identical DNA can differentiate into specialized cell types through epigenetic regulation, with particular focus on applications in understanding tumorigenesis where epigenetic machinery malfunctions. Her work combines high-throughput epigenomic data with advanced computational approaches to address complex biological questions. Analysis of her recent publications reveals a strong focus on epigenomic data analysis, machine learning applications in biology, and computational approaches to understanding gene regulation. Her work spans from fundamental epigenetic mechanisms to practical applications in disease research, with growing emphasis on individual-specific epigenomic analysis and explainable AI in biomedical contexts. UKRI Future Leaders Fellowship (2020, £1.6 million) Marie Curie Fellowship EMBO Fellowship Dr. Schweikert actively supervises PhD students and has received significant research funding for projects including 'Machine Learning Methods to Re-Annotate Histone Modifications,' 'Unlocking The Alternative Splicing Code,' and 'GPU-Based Machine Learning System For Fundamental Biological Research.' She is involved in multiple interdisciplinary collaborations and frequently presents her work at major conferences including ELLIS Health program retreat, Epigenetics Meetings, and RECOMB workshops. She maintains active research laboratories in both Dundee and Tuebingen, fostering international collaboration between computational biologists, machine learning experts, and experimental biologists to advance our understanding of epigenetic regulation in health and disease.

• Computational Biology
• Machine Learning
• Epigenetics
• +۶ مورد دیگر

Cathy Wu is a distinguished academic holding the Unidel Edward G. Jefferson Chair in Engineering and Computer Science at the University of Delaware. She serves as Director of the Center for Bioinformatics & Computational Biology (CBCB), Data Science Institute (DSI), and Protein Information Resource (PIR). Her roles include professorships in the Departments of Computer & Information Sciences and Biological Sciences. Education: BS in Plant Pathology (National Taiwan University, 1978), MS and PhD in Plant Pathology (Purdue University, 1982–1984), and a second MS in Computer Science (University of Texas at Tyler, 1989). She completed postdoctoral training in Molecular Biology at Michigan State University (1985–1986). Research interests focus on computational biology, bioinformatics, and data science with emphasis on protein informatics, biological text mining, ontology development, gene-disease-drug networks, and machine learning applications. She leads initiatives in integrating FAIR principles into biological databases like UniProt and InterPro. Her work bridges computational methods with biomedical challenges, including cancer genomics, epigenetic regulation, and proteomic analyses. She has spearheaded educational programs such as the Online Graduate Certificates in Applied Bioinformatics and Biomedical Informatics and Data Science. Her contributions include over 290 peer-reviewed publications (48,000+ citations, h-index 71) and authored/co-authored four books on bioinformatics. She directs multidisciplinary research teams and collaborates internationally on projects like the HALO study on ovarian cancer genetics. Awards and recognition are implied through her leadership roles and academic appointments, though specific prizes are not listed here. Her grants and funding support large-scale initiatives in bioinformatics infrastructure and translational research.

• Computational Biology
• Bioinformatics
• Data Science
• +۸ مورد دیگر

Hong Han is an Assistant Professor in the Department of Biochemistry & Biomedical Sciences within McMaster University's Faculty of Health Sciences and a member of the Centre for Discovery in Cancer Research (CDCR). She holds a Canada Research Chair and leads the Han Lab, which focuses on cancer biology, RNA regulation, and innovative high-throughput technologies for therapeutic discovery. Dr. Han earned her Ph.D. from the University of Toronto (2010-2016) and has established herself as a leading researcher in glioblastoma and alternative splicing regulation. Her interdisciplinary research integrates cancer biology, RNA science, and multilayer gene regulation to uncover mechanisms underlying cancer progression and treatment resistance. Her laboratory pioneers integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. The research focuses on three main areas: alternative splicing regulation in cancer (particularly glioblastoma and prostate cancer), multilayer mechanisms of glioblastoma heterogeneity and microenvironment evolution, and multiplexed screening approaches for therapeutic discovery in treatment-resistant cancers. Analysis of Dr. Han's recent publications reveals a strong emphasis on single-cell technologies to characterize glioblastoma heterogeneity, minimal residual disease states, and tumor-immune interactions. Her work increasingly bridges basic RNA biology with translational applications, particularly in developing novel therapeutic strategies targeting splicing networks and immune evasion mechanisms. Canada Research Chair Dr. Han teaches Advanced Techniques in the Biomedical Sciences (BIOCHEM 734). Her research program is supported by multiple funding sources, as evidenced by her extensive publication record in high-impact journals including Nature, Cell, Molecular Cell, and Nature Communications. She employs a comprehensive approach combining in vitro, in vivo, and patient cohort studies with cutting-edge genomic technologies. The Han Lab has developed innovative multiplexed screening platforms that enable simultaneous interrogation of thousands of conditions, ranging from CAR-T cells to small molecule therapeutics. This approach accelerates the discovery of novel cancer targets and therapeutic strategies for treatment-resistant cancers.

• Cancer Biology
• Gene Regulation
• RNA Splicing
• +۵ مورد دیگر

Dr. Yang Zhang is a Professor at the National University of Singapore (NUS), holding appointments in the Department of Computer Science (School of Computing) and the Department of Biochemistry (Yong Loo Lin School of Medicine). He also leads the Zhang Lab, which focuses on AI-driven computational methods for protein structure prediction and design. Previously, he was a Professor at the University of Michigan. His research integrates artificial intelligence, deep learning, and physics-based models to address challenges in computational biology. Affiliations: School of Computing; Yong Loo Lin School of Medicine; Cancer Science Institute of Singapore Key Roles: Principal Investigator of Zhang Lab; Developer of I-TASSER algorithm Research interests span AI-driven protein design, deep learning for RNA structure prediction, and drug discovery. Projects include the EvoDesign server for protein interaction design and TripletRes for coevolution-based contact prediction. Major contributions include the I-TASSER algorithm, ranked top in CASP experiments for protein structure prediction. Awards: Alfred P. Sloan Award, NSF CAREER Award, and seven-time Highly Cited Researcher (2015–2021).

• Computational Biology
• Bioinformatics
• Algorithms
• +۶ مورد دیگر

Arthur Lesk is a Professor of Biochemistry and Molecular Biology at Pennsylvania State University since 2003. Previously, he held roles including faculty member at the clinical school of the University of Cambridge (1990–2003), group leader at the European Molecular Biology Laboratory (1987–1990), and professor of chemistry at Fairleigh Dickinson University (1971–1987). He earned a B.A. from Harvard University (1961), Ph.D. from Princeton University (1966), and M.Sc. from the University of Cambridge (1999). His research focuses on bioinformatics, genomics, protein structure, and molecular biology. He has authored 189 scientific articles, 10 books, and has an h-index of 61. Notable works include Protein Science (2021) and Introduction to Bioinformatics (2019). Lesk chairs CODATA’s Biological Macromolecules Task Group and is a Fellow of the AAAS and Royal Society of Biology. He maintains active teaching and research roles, delivering lectures globally. His contributions include advancing protein structure databases and computational methods for molecular biology. Lesk is a Life Member of Clare Hall, Cambridge, and has held visiting positions at universities in New Zealand, Australia, and Europe.

• Bioinformatics
• Genomics
• Protein Structure
• +۳ مورد دیگر