جست‌وجوی استاد و پژوهشگر

Clavia Ruth Wooton-Keeمشاهده پروفایل

استادیار

• Hepatic Metabolism
• Nuclear Receptors
• Wilson's Disease
• +۱۲ مورد دیگر

Clavia Ruth Wooton-Kee, Ph.D. , is an Assistant Professor at Baylor College of Medicine in the Department of Pediatrics, with secondary appointments in Nutrition and Molecular and Cellular Biology. She leads an independent research laboratory at the USDA/ARS Children’s Nutrition Research Center in Houston, Texas, where she investigates the role of nuclear receptors in hepatic metabolism and chronic liver diseases, particularly Wilson’s disease. Her lab uses the Atp7b-/- mouse model to study metabolic dysfunction and copper-induced redox stress. Education: BSc in Biology and Chemistry, Union College (1996) MS in Biochemistry, University of Louisville School of Medicine (1999) PhD in Toxicology, University of Kentucky College of Medicine (2008) Her research focuses on how excessive copper disrupts nuclear receptor signaling (FXR, HNF4α, LRH-1), leading to bile acid dysregulation, mitochondrial damage, and spontaneous liver nodules. She explores therapeutic strategies involving nuclear receptor ligands and investigates transcriptomic and proteomic signatures in chronic liver diseases. Analysis of her recent publications reveals a strong focus on nuclear receptor biology, bile acid metabolism, Wilson’s disease, and metabolic adaptations during lactation. Her work spans molecular mechanisms, animal models, and translational applications, with a growing emphasis on gene regulation and therapeutic targeting. Scientific Awards: Presidential Poster Award, AASLD: The Liver Meeting, 2023 Dr. Wooton-Kee has received continuous grant funding from NIH/NIDDK and USDA/CRIS, including an R01 grant on nuclear receptor dysfunction in Wilson’s disease and a K01 Career Development Award. She has mentored researchers and presented her findings internationally, including at the Wilson Disease Aarhus Symposium in 2024. She also serves as a Faculty Senator at Baylor College of Medicine. Her lab is part of the USDA/ARS Children’s Nutrition Research Center, which provides state-of-the-art facilities including advanced laboratories, metabolic kitchens, and research volunteer accommodations, enabling cutting-edge research in pediatric nutrition and liver disease.

• Gastroenterology
• Medical Education
• Molecular Nutrition
• +۳ مورد دیگر

Martin Veysey is a Professor of Rural Medicine at Flinders University and a Consultant Gastroenterologist at Royal Darwin Hospital. He has held academic appointments including Senior Lecturer at the University of Newcastle and MBBS Programme Director at Hull York Medical School. His research spans gastroenterology , medical education , and molecular nutrition . Education MBBS, University of London (1991) Doctor of Medicine (MD), University of London (2001) Graduate Certificate in Tertiary Teaching, University of Newcastle (2010) Master of Clinical Education, Flinders University (2015) MBA in Higher Education Management, UCL (2017) Research Contributions His work explores the gut microbiome , bowel transit time , and gastrointestinal disease links to colorectal cancer , diverticulosis , and hemorrhoids . Recent studies include the vitamin D-folate hypothesis in human evolution and gut-lung axis in viral infections. Scientific Awards Fellow of the Royal College of Physicians (FRCP), UK Fellow of the Royal Australasian College of Physicians (FRACP) Professional Roles Martin leads undergraduate/postgraduate education initiatives, chairs the RACP CPD Committee , and is an Associate Editor for BMC Medical Education . He collaborates with institutions in Australia and the UK.

Benjamin C Warfمشاهده پروفایل

استاد

• Neurosurgery
• Global Health
• Pediatric Neurology
• +۴ مورد دیگر

Benjamin C Warf, MD is the Cummings Foundation Professor at Harvard Medical School and a neurosurgeon specializing in global health and pediatric hydrocephalus. His work focuses on improving surgical outcomes for children with hydrocephalus and spina bifida in low-resource settings, particularly sub-Saharan Africa. Dr. Warf pioneered the ETV/CPC surgical technique as an alternative to shunts, demonstrating comparable neurodevelopmental outcomes while reducing costs. He has extensively studied the epidemiology, pathogenesis, and socioeconomic impacts of hydrocephalus, including its correlation with infectious diseases like Paenibacillus infections and environmental factors such as arsenic exposure. His research has informed global health policy, including testimony before the U.S. House of Representatives that led to legislative proposals like the Global Brain Health Act. Dr. Warf collaborates with institutions worldwide through initiatives like the Paul Farmer Collaborative, emphasizing capacity-building in neurosurgical training and resource-limited healthcare systems. His work integrates clinical innovation with public health strategies to address disparities in pediatric neurosurgical care. Key contributions include randomized trials evaluating ETV/CPC efficacy, cost-benefit analyses of surgical interventions, and molecular studies linking environmental toxins to neural tube defects. He advocates for sustainable healthcare solutions through training programs, telemedicine mentorship, and partnerships with governments and NGOs.

Ville Männistöمشاهده پروفایل

استاد

• Liver diseases
• Steatotic liver disease
• Metabolic dysfunction-associated steatotic liver disease (MASLD)
• +۶ مورد دیگر

Professor Ville Männistö is a leading academic in gastroenterology and hepatology at the University of Eastern Finland, holding the Professorship of Gastroenterology since September 2024. He is affiliated with the Institute of Clinical Medicine within the School of Medicine, Faculty of Health Sciences. His academic career includes roles as Research Director, Clinical Researcher, and head of gastroenterology specialization training programs at the University of Eastern Finland and Kuopio University Hospital. He completed his Licentiate of Medicine (2008), MD (2016), and became a Docent in Gastroenterology (2021). His research focuses on liver disease epidemiology, particularly metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-related liver disease (ALD). Key areas include fibrosis progression mechanisms, population-level liver risk stratification, and the synergistic effects of metabolic and alcohol-related factors. He has pioneered the CLivD risk score for liver-related event prediction and contributed to understanding genetic and environmental influences on liver health. Professor Männistö leads large-scale cohort studies such as the METSIM study tracking liver health in Eastern Finnish men, and has published extensively on biomarkers (e.g., indole-3-propionic acid), metabolic signatures, and clinical outcomes. His work integrates genetic, metabolic, and epidemiological data to advance early detection and prevention strategies for severe liver outcomes. His research also addresses global health challenges like rising inflammatory bowel disease prevalence and the evolving terminology of liver diseases. He collaborates internationally on projects such as the EU-funded METSIM study and liver metabolomics initiatives.

• Colorectal Cancer Research
• Metabolomics
• Nutritional Oncology
• +۳ مورد دیگر

E. H. van Roekel is a researcher at the German Cancer Research Center (DKFZ) within the Division of Cancer Epidemiology and Department of Molecular Epidemiology. Their work focuses on molecular epidemiology of colorectal cancer, with specialization in metabolomics and nutritional factors influencing cancer outcomes. Dr. van Roekel's research spans multiple critical areas in cancer epidemiology including tryptophan-kynurenine pathway metabolites, one-carbon metabolism, and B-vitamin biomarkers in relation to colorectal cancer progression and patient survival. They investigate how circadian rhythms affect cancer-related fatigue and quality of life in survivors, while also examining metabolic signatures associated with obesity and cancer risk. Their methodological expertise includes plasma metabolomic profiling and careful handling of biospecimens for research purposes, as evidenced by publications on pre-analytical factors in metabolomic studies. Analysis of Dr. van Roekel's publication record reveals consistent involvement in large-scale international consortia including ColoCare and FOCUS, enabling robust epidemiological studies with substantial patient cohorts. Their research demonstrates a clear trajectory from basic metabolomic discovery to clinical applications, with increasing focus on how molecular findings translate to patient quality of life and survivorship outcomes. The collaborative nature of their work spans multiple European institutions and involves close partnerships with clinical oncologists, epidemiologists, and basic scientists. Dr. van Roekel actively contributes to DKFZ's mission of advancing cancer research through participation in multi-center studies requiring careful standardization of protocols. While specific grant information isn't detailed in the available publications, their involvement in major research initiatives suggests successful funding from prominent cancer research organizations. Their work bridges laboratory findings with clinical applications, contributing to the development of potential biomarkers for cancer staging, recurrence prediction, and personalized treatment approaches.

• Cancer Epidemiology
• Nutritional Oncology
• Colorectal Cancer Research
• +۳ مورد دیگر

S. O. Breukink is a researcher at the German Cancer Research Center (Deutsches Krebsforschungszentrum) in Heidelberg, Germany, specializing in cancer epidemiology with a focus on colorectal cancer. Their work primarily examines the relationships between nutritional factors, circadian rhythms, and quality of life outcomes in colorectal cancer patients and survivors. Research interests center on nutritional oncology, particularly the role of B vitamins and folate in cancer progression and survivorship. Breukink's work investigates how biomarkers related to one-carbon metabolism affect cancer recurrence, survival rates, and quality of life metrics in colorectal cancer patients. Their research employs longitudinal study designs and consortium-based approaches to analyze large patient cohorts across multiple European institutions. The publication record demonstrates consistent output in high-impact oncology and nutrition journals, with recent work focusing on vitamin B6 status, sleep quality, fatigue management, and metabolomic profiling in colorectal cancer contexts. Much of this research has been conducted through international collaborations including the FOCUS consortium. Breukink has contributed to significant findings regarding the dual role of folates in colorectal cancer development and the associations between vitamin status and cancer outcomes. Their work bridges nutritional science, cancer epidemiology, and patient-centered outcomes research.

• sports genomics
• gene doping
• obesity and nutria-genetics
• +۲ مورد دیگر

Korkut ULUCAN serves as Associate Professor at Marmara University, Faculty of Dentistry, Department of Medical Biology and Genetics, and as adjunct faculty member at Üsküdar University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics. His academic career bridges medical genetics with sports science, focusing on practical applications of genetic research. Dr. ULUCAN completed both his MSc and PhD at Marmara University, Faculty of Medicine, Department of Medical Biology and Genetics, establishing his foundation in molecular genetics and its clinical applications. His educational background directly informs his current research directions in personalized medicine and sports genomics. His primary research interests include sports genomics, gene doping, obesity and nutri-genetics, personalized medicine, and genetic counseling. Dr. ULUCAN has pioneered work examining how genetic polymorphisms influence athletic performance across various sports including cycling, soccer, volleyball, and skiing. His research extends to neuropsychiatric conditions, investigating genetic factors in bipolar disorder, autism spectrum disorder, schizophrenia, and depression. Dr. ULUCAN's publication record reveals consistent research productivity with emphasis on Turkish populations. His work spans from basic genetic analysis of polymorphisms to clinical applications in sports performance optimization and personalized treatment approaches. The interdisciplinary nature of his research connects molecular biology, sports science, and clinical psychiatry. As academic advisor for Genigma Genetic Research Center—the first specialized biotechnology company in Turkey focusing on sports and nutri-genetics—Dr. ULUCAN translates research findings into practical applications for athletes and patients. This role positions him at the forefront of applying genetic insights to real-world health and performance challenges. Dr. ULUCAN actively participates in national and international conferences including the International Sports Sciences Congress and Basic Clinical and Multimodal Imaging Conference. His collaborative projects, including multiple 2025 initiatives examining genetic polymorphisms in neuropsychiatric conditions, demonstrate his ongoing commitment to advancing the field of personalized medicine through genetic research.

• Clinical Nutrition
• Obesity and Metabolic Syndrome
• Bariatric Surgery
• +۷ مورد دیگر

Maria Flora Ferreira Sampaio De Carvalho Correia is an Invited Full Professor at the Faculty of Nutrition and Food Sciences, University of Porto, where she has been a leading figure in clinical nutrition and metabolic research. She holds a Doctorate in Biomedical Sciences from the Faculty of Medicine, University of Lisbon, and an Agregado in Clinical Nutrition from the University of Porto. Her academic career is deeply rooted in Portuguese higher education and clinical research institutions. Education: Bachelor in Nutrition, University of Porto, 1980 Licentiate in Nutritional Sciences, University of Porto, 1988 Doctorate in Biomedical Sciences, University of Lisbon, 2004 Agregado in Clinical Nutrition, University of Porto, 2006 Her research interests center on obesity, bariatric surgery, metabolic syndrome, eating behavior, and nutritional assessment . She investigates biochemical, anthropometric, and psychosocial factors influencing nutritional outcomes in diverse populations, from children to elderly patients. Her work often employs bioelectrical impedance analysis and population-based studies to assess body composition and nutritional status. Her recent publications (2020–2024) reflect a strong focus on nutritional deficiencies post-bariatric surgery, gut microbiota changes, cardiovascular risk reduction, and psychosocial aspects of eating . These studies demonstrate a trend toward interdisciplinary, clinically relevant research with implications for public health and personalized nutrition. Scientific Awards: Maria Flora Correia has supervised numerous research projects and mentored students, though specific advisees are not listed in the provided text. She has contributed to national and international guidelines on obesity and nutrition. Her work has been supported by institutional and potentially national research grants, though specific funding details are not mentioned. She leads research within the Faculty of Nutrition and Food Sciences and collaborates with clinical teams across Portugal, particularly in bariatric and nephrology units. Labs and Research Teams: While no specific lab name is provided, her research is conducted within the academic and clinical networks of the University of Porto, particularly in collaboration with hospitals and dialysis centers. She is involved in projects like PRONUTRISENIOR, indicating leadership in geriatric nutrition initiatives.

• Biomedical Engineering
• Medical Imaging
• Nanoparticle Drug Delivery
• +۳ مورد دیگر

Thomas Nielsen is an Associate Professor at the Department of Electrical and Computer Engineering, Aarhus University, specializing in Biomedical Engineering. His research bridges medical instrumentation development and clinical oncology applications, with particular expertise in diagnostic imaging technologies. Research Focus: Medical imaging innovation including advanced MRI techniques (hyperpolarized 13 C, 19 F, DCE-MRI) and photoplethysmography for cancer diagnostics Nanoparticle engineering for targeted drug delivery and contrast enhancement Tumor microenvironment analysis focusing on vasculature, hypoxia, and metabolic pathways Development of theranostic platforms combining diagnostics and therapeutics Publication Analysis: His recent work (2013-2022) demonstrates consistent focus on oncology imaging, with 73% of publications involving cancer diagnostics. Key methodological themes include nanoparticle-based contrast agents (33%), MRI technique development (40%), and photoplethysmography applications (13%). Research outputs frequently involve interdisciplinary collaboration across engineering, materials science, and clinical oncology. Projects: Directed three major research initiatives: F127-Folate coated SPION for cancer detection (2014) Chitosan coated PLGA PFOB nanoparticles for cell migration tracking (2013-2014) PLGA-PEG-Folate multimodal nanoparticles for combined MRI/NIR imaging and chemotherapy (2011-2014) Laboratory Affiliations: Conducts research through the Biomedical Engineering laboratories within the Department of Electrical and Computer Engineering, utilizing facilities for nanoparticle synthesis, optical imaging, and magnetic resonance experimentation.

• Cancer biology
• Protein kinase signal transduction
• Genome engineering
• +۲ مورد دیگر

Morten Frödin is an Associate Professor and group leader at the Biotech Research & Innovation Center (BRIC), University of Copenhagen, where he has been conducting research since 2004. His work primarily focuses on protein kinase signaling pathways and their roles in health and disease, particularly in cancer biology and genome engineering. Education: MSc in Cell Biology from University of Copenhagen (1992) PhD in Molecular Biology from University of Copenhagen (1997) focusing on growth factor regulation of proliferation and differentiation of neuronal cells Dr. Frödin's research interests center on cancer biology, protein kinase signal transduction, and genome engineering. His work bridges molecular mechanisms with potential therapeutic applications, particularly in understanding how protein kinases regulate cellular processes and how these pathways become dysregulated in cancer. His group has made significant contributions to CRISPR-based genome editing technologies and their applications in cancer research. Analysis of his recent publications reveals a strong focus on cancer metabolism, genome maintenance mechanisms, and precision approaches to understanding genetic variants. His work demonstrates a progression from fundamental signaling mechanisms toward translational applications, with increasing emphasis on CRISPR technology and its clinical implications in cancer diagnostics and treatment. As group leader of the Frödin Group at BRIC, he maintains an active research program with numerous international collaborations. His work has attracted attention from news outlets, policy sources, and patent applications, indicating the translational potential of his research. The group's work spans basic molecular mechanisms to potential clinical applications, with particular strength in genome editing technologies and cancer signaling pathways.

Mark Daniel Flemingمشاهده پروفایل

استاد

• Iron Metabolism
• Hematology
• Erythroid Cell Biology
• +۴ مورد دیگر

Mark Daniel Fleming is a distinguished researcher and physician-scientist at Boston Children's Hospital, affiliated with Harvard Medical School. His work primarily focuses on understanding iron metabolism in erythroid cells and the genetic basis of blood disorders, particularly sideroblastic anemias. Education: Undergraduate: Molecular Biology, Princeton University (1987) Graduate: DPhil in Organic Chemistry, University of Oxford (1990) Medical Degree: Harvard Medical School (1993) Residency: Anatomic Pathology, Brigham and Women's Hospital (1997) Fellowship: Hematopathology, Brigham and Women's Hospital (1997) Postdoctoral Fellowship: Division of Hematology/Oncology, Children's Hospital Dr. Fleming's research is centered on determining how erythroid cells acquire and utilize iron. His laboratory pursues two main approaches: positionally cloning and characterizing genes underlying mouse hereditary defects in erythroid iron metabolism, and using targeted mutagenesis in mice to study proteins implicated in sideroblastic anemias. These bone marrow disorders involve pathologic iron deposits in mitochondria, which play a critical role in iron and heme metabolism. A key focus of his work is characterizing proteins responsible for mitochondrial iron import and utilization, which has significant implications for understanding and treating various blood disorders. Analysis of Dr. Fleming's recent publications (2022-2025) reveals a strong focus on mitochondrial DNA variants in rare diseases, sideroblastic anemias, iron-related disorders, and genomic approaches to diagnosing hematological conditions. His work spans from basic molecular mechanisms of iron metabolism to clinical applications in diagnosing and treating blood disorders. There's a clear progression from studying fundamental iron metabolism pathways to applying genomic technologies for diagnosing complex hematological conditions. Scientific Awards: Pew Fellow in Biomedical Research Dr. Fleming has led numerous research projects investigating iron metabolism and blood disorders. His laboratory has made significant contributions to understanding the genetic basis of sideroblastic anemias and mitochondrial iron metabolism. His work has been consistently supported by research grants focused on hematological disorders and iron metabolism. While specific grant details aren't provided in the text, his extensive publication record spanning decades indicates sustained research funding. Dr. Fleming's research unit within the Pathology Department at Boston Children's Hospital focuses on the intersection of iron metabolism, mitochondrial function, and erythropoiesis. His team employs a range of approaches including mouse models, genomic analysis, and molecular characterization of iron-related proteins to advance understanding of blood disorders.

Carl F. Nathanمشاهده پروفایل

استاد

• Infection biology of Mycobacterium tuberculosis
• Host-pathogen interactions
• Innate immunity
• +۶ مورد دیگر

Carl F. Nathan is the R.A. Rees Pritchett Professor of Microbiology and Professor of Microbiology and Immunology & Medicine at Weill Cornell Medical College. His research focuses on Mycobacterium tuberculosis biology at the basic-translational interface , particularly host-pathogen interactions , macrophage immunity , and antimicrobial resistance mechanisms . The Nathan Lab investigates both pathogen-directed and host-directed therapies for TB, with a long-standing interest in reactive oxygen/nitrogen intermediates and iNOS regulation . The lab collaborates with Sabine Ehrt's, Kyu Rhee's, and Dirk Schnappinger’s labs, plus Jeremy Rock at Rockefeller University and the Center for Global Health at Weill Cornell. Key discoveries: IFN-γ as macrophage activator, TGF-β/IL-10 as deactivating factors, ROI/RNI effector systems, Mtb resistance genes (proteasome, Uvr pathway) Translational work: First cytokine therapy for leprosy, current TB drug screening pipelines

• Molecular Diagnostics
• DNA Analysis
• Homocysteine Metabolism
• +۵ مورد دیگر

Brian Gilfix, MD, PhD is an active Associate Professor in the Department of Medicine at McGill University's Faculty of Medicine and Health Sciences and serves as an Investigator at the Research Institute of the McGill University Health Centre (RI-MUHC) at the Glen site. His academic appointment is specifically within the Division of Biochemistry at the MUHC, where he contributes to both clinical and research activities focused on molecular diagnostics and metabolic disorders. Dr. Gilfix's research program centers on developing innovative techniques for analyzing DNA mutations and measuring blood substances for disease diagnosis. His work prominently features homocysteine analysis, HPLC methodology, and molecular diagnostics approaches. His expertise spans genetic disorders, vitamin metabolism (particularly B12 and folate), methylmalonic aciduria, and laboratory testing methodologies. His research has significant clinical applications in hematology, metabolic diseases, and genetic diagnostics. The publication record reveals consistent scholarly output with a focus on metabolic disorders and diagnostic techniques. Recent work shows expansion into neurodegenerative disease biomarkers (Alzheimer's research) while maintaining his longstanding expertise in vitamin metabolism and genetic disorders. His collaborative pattern indicates strong research partnerships, particularly with Rosenblatt DS and Watkins D, suggesting integration within specialized research networks focused on inborn errors of metabolism. Dr. Gilfix's research has direct clinical applications in diagnostic laboratory medicine, particularly in identifying genetic mutations and metabolic abnormalities. His work bridges basic science with clinical practice, contributing to improved diagnostic approaches for complex metabolic conditions. The consistent publication record across multiple decades demonstrates sustained scholarly activity and evolving research interests within the molecular diagnostics field.

Rita S. Strakovskyمشاهده پروفایل

دانشیار

• Maternal obesity and lipid metabolism
• Maternal macronutrient intake and metabolic diseases
• Endocrine disrupting chemicals and interaction with diet
• +۳ مورد دیگر

Rita S. Strakovsky is an Associate Professor in the Department of Food Science and Human Nutrition at Michigan State University , affiliated with the College of Agriculture & Natural Resources . Her research bridges environmental toxicology and maternal-child health , focusing on how endocrine-disrupting chemicals (EDCs) interact with maternal diet to influence fetal development and long-term health outcomes . Education : B.S. in Molecular and Cellular Biology (2005) R.D. in Registered Dietitian (2011) Ph.D. in Nutritional Sciences (2011) Research Themes : Epigenetic regulation of energy metabolism EDC-diet interactions in pregnancy Maternal adiposity and placental function Environmental impacts on women's health Lipidomic and hormonal biomarkers Key Collaborations : Illinois Kids Development Study (I-KIDS) Environmental Influences on Child Health Outcomes cohort (ECHO) National Institutes of Health-funded projects Scientific Contributions : Her work has established mechanistic links between phthalate exposure , maternal obesity , and fetal epigenetic programming . Current studies examine chemical mixtures and racial disparities in environmental exposures via the ECHO program .

• Cancer Epidemiology
• Colorectal Cancer Research
• Molecular Oncology
• +۲ مورد دیگر

U. Peters is a researcher at the German Cancer Research Center (DKFZ) specializing in cancer epidemiology with a focus on colorectal cancer. With numerous publications from 2020-2025, Peters contributes significantly to understanding the molecular subtypes of colorectal cancer, risk factors including lifestyle and genetic components, and the application of advanced statistical methods like Mendelian randomization. Peters' research spans multiple areas including the relationship between physical activity and cancer subtypes, the impact of body composition metrics on cancer risk, and the role of dietary factors in colorectal cancer development. The work often involves large-scale epidemiological studies and collaborations with international consortia such as the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Recent publications demonstrate expertise in applying modern analytical approaches to cancer epidemiology, with particular attention to molecular mechanisms and subtype-specific risk factors. The research frequently examines how genetic, metabolic, and lifestyle factors interact to influence cancer risk and outcomes, contributing to more precise prevention strategies. Peters has contributed to significant findings in colorectal cancer research, including studies on the relationship between adiposity markers and cancer risk, the role of advanced glycation end-products in cancer mortality, and the impact of sleep patterns on colorectal cancer development. The work often appears in high-impact journals including International Journal of Cancer , Cancer Epidemiology, Biomarkers & Prevention , and Nature Communications .