Chongzhi Zangمشاهده پروفایل
دانشیار
- Computational Biology
- Cancer Genomics
- Epigenetics
- +۷ مورد دیگر
Chongzhi Zang is an Associate Professor at the University of Virginia School of Medicine with primary appointment in the Department of Genome Sciences (formerly Center for Public Health Genomics). He holds additional faculty appointments in the Departments of Public Health Sciences, Biomedical Engineering, and Biochemistry and Molecular Genetics. Dr. Zang is also a faculty member in the UVA Cancer Center and the Data Science Institute, where he serves as the inaugural Director of Computational Genomics. His educational background includes a B.S. in Physics from Peking University (2005), a Ph.D. in Physics from The George Washington University (2010), and postdoctoral training in Computational Biology at Harvard University (2016). Dr. Zang's research focuses on computational biology and functional genomics, with particular expertise in cancer epigenomics. His lab develops computational methods and data science approaches to study how genes work in chromatin and how they dysfunction in diseases like cancer. Key research areas include algorithm development for high-throughput genomic data analytics, integrative modeling of gene regulatory networks, and analysis of chromatin architecture in mammalian cell systems. His recent publications demonstrate significant contributions to understanding transcriptional regulation, phase-separated condensates, chromatin accessibility analysis, and computational methods for single-cell multiomics data. The research shows a strong trend toward developing innovative computational tools that bridge molecular biology and data science to address fundamental questions in gene regulation and cancer biology. University of Virginia Research Excellence Award (2020) NIGMS Maximizing Investigators' Research Award (MIRA) (2019-2024) NCI Career Transition Award (2017-2020) Leukemia and Lymphoma Society Fellow Award (2012-2015) Dimitris N. Chorafas Foundation Prize (2010) School of Medicine Dean's Award for Excellence in Research (2024) Vivian Pinn Scholar by UVA School of Medicine (2024) Dr. Zang actively mentors a large research team including postdoctoral associates, graduate students, and undergraduates. His lab has secured substantial grant funding including NIH R35 MIRA, R21, and R01 grants, as well as pilot funding from the UVA Cancer Center. He has developed several widely-used computational tools including BART (Binding Analysis for Regulation of Transcription), BARTweb, BART3D, and IGN normalization methods that are used by researchers worldwide. The Zang Lab for Computational Biology and Functional Genomics is located in the Medical Center's West Complex and maintains active collaborations across UVA and with external institutions. The lab is highly productive with numerous publications in top journals including Nature, Nature Genetics, and Nature Immunology, and has developed significant expertise in single-cell genomics, chromatin architecture analysis, and computational methods for cancer genomics.









