Irene A. Chen is a Professor in the Department of Biochemistry at the University of California, Los Angeles (UCLA) , within the Henry Samueli School of Engineering and Applied Science (SEAS) . She leads the Chen Laboratory , which focuses on biomolecular design and evolution in nanoscale systems , including protocells and bacteriophages . Her research spans synthetic biology , origin of life , RNA evolution , phage engineering , and antimicrobial applications . Her lab uses in vitro evolution , high-throughput sequencing , and nanomaterial-bioconjugation to explore how life-like systems can be constructed and controlled. Research Interests: Biomolecular design and evolution in nanoscale systems Protocell formation and RNA encapsulation Bacteriophage engineering for antimicrobial therapy Fitness landscapes in RNA evolution Phage-nanoparticle conjugates for imaging and therapy Recent Work Trends: Her recent publications (2024–2025) reflect a strong focus on phage-based therapeutics , protocell systems , and RNA evolution . Many papers explore antimicrobial applications using engineered phages, nanoparticle conjugates , and RNA catalysis in prebiotic contexts. Scientific Awards: No specific awards are listed in the provided text. Grants & Funding: While no specific grant details are provided, her extensive publication record and lab operations suggest active funding from NIH, NSF, or other biomedical engineering and synthetic biology programs. Laboratory & Team: The Chen Laboratory is located at UCLA SEAS and focuses on interdisciplinary research combining chemistry , biology , and engineering to address fundamental questions in origin of life and antimicrobial innovation .










