معرفی
Irene A. Chen is a Professor in the Department of Biochemistry at the University of California, Los Angeles (UCLA), within the Henry Samueli School of Engineering and Applied Science (SEAS). She leads the Chen Laboratory, which focuses on biomolecular design and evolution in nanoscale systems, including protocells and bacteriophages.
Her research spans synthetic biology, origin of life, RNA evolution, phage engineering, and antimicrobial applications. Her lab uses in vitro evolution, high-throughput sequencing, and nanomaterial-bioconjugation to explore how life-like systems can be constructed and controlled.
Research Interests:
- Biomolecular design and evolution in nanoscale systems
- Protocell formation and RNA encapsulation
- Bacteriophage engineering for antimicrobial therapy
- Fitness landscapes in RNA evolution
- Phage-nanoparticle conjugates for imaging and therapy
Recent Work Trends: Her recent publications (2024–2025) reflect a strong focus on phage-based therapeutics, protocell systems, and RNA evolution. Many papers explore antimicrobial applications using engineered phages, nanoparticle conjugates, and RNA catalysis in prebiotic contexts.
Scientific Awards: No specific awards are listed in the provided text.
Grants & Funding: While no specific grant details are provided, her extensive publication record and lab operations suggest active funding from NIH, NSF, or other biomedical engineering and synthetic biology programs.
Laboratory & Team: The Chen Laboratory is located at UCLA SEAS and focuses on interdisciplinary research combining chemistry, biology, and engineering to address fundamental questions in origin of life and antimicrobial innovation.
