Nicole C. Riddle is a Professor and Associate Chair for Research and Facilities in the Department of Biology at the University of Alabama at Birmingham (UAB). She holds a B.S. in Biology from the University of Missouri Columbia and a Ph.D. in Evolutionary and Population Biology from Washington University in St. Louis. Her research focuses on epigenetics and chromatin dynamics, particularly in the context of aging and sex differences using Drosophila melanogaster as a model system. Dr. Riddle's work explores how epigenetic mechanisms influence lifespan, genome stability, and phenotypic variation. She has pioneered the use of Drosophila to study exercise-induced physiological changes and their genetic underpinnings. Her lab investigates the roles of HP1 proteins in transcriptional regulation and chromatin organization, with recent studies emphasizing cross-species comparisons of aging mechanisms. Her research has been supported by grants including the BII: IISAGE project on sex-specific aging mechanisms. Notable contributions include developing novel tools like the Rotating Exercise Quantification System (REQS) to measure Drosophila activity levels. Dr. Riddle actively mentors students and postdoctoral researchers, inviting inquiries via riddlenc@uab.edu to join her lab.
Hong Han is an Assistant Professor in the Department of Biochemistry & Biomedical Sciences within McMaster University's Faculty of Health Sciences and a member of the Centre for Discovery in Cancer Research (CDCR). She holds a Canada Research Chair and leads the Han Lab, which focuses on cancer biology, RNA regulation, and innovative high-throughput technologies for therapeutic discovery. Dr. Han earned her Ph.D. from the University of Toronto (2010-2016) and has established herself as a leading researcher in glioblastoma and alternative splicing regulation. Her interdisciplinary research integrates cancer biology, RNA science, and multilayer gene regulation to uncover mechanisms underlying cancer progression and treatment resistance. Her laboratory pioneers integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. The research focuses on three main areas: alternative splicing regulation in cancer (particularly glioblastoma and prostate cancer), multilayer mechanisms of glioblastoma heterogeneity and microenvironment evolution, and multiplexed screening approaches for therapeutic discovery in treatment-resistant cancers. Analysis of Dr. Han's recent publications reveals a strong emphasis on single-cell technologies to characterize glioblastoma heterogeneity, minimal residual disease states, and tumor-immune interactions. Her work increasingly bridges basic RNA biology with translational applications, particularly in developing novel therapeutic strategies targeting splicing networks and immune evasion mechanisms. Canada Research Chair Dr. Han teaches Advanced Techniques in the Biomedical Sciences (BIOCHEM 734). Her research program is supported by multiple funding sources, as evidenced by her extensive publication record in high-impact journals including Nature, Cell, Molecular Cell, and Nature Communications. She employs a comprehensive approach combining in vitro, in vivo, and patient cohort studies with cutting-edge genomic technologies. The Han Lab has developed innovative multiplexed screening platforms that enable simultaneous interrogation of thousands of conditions, ranging from CAR-T cells to small molecule therapeutics. This approach accelerates the discovery of novel cancer targets and therapeutic strategies for treatment-resistant cancers.
Yang Luo is a Kennedy Trust Senior Research Fellow in Data Science at the University of Oxford's Kennedy Institute of Rheumatology. His research bridges statistical genomics and computational immunology to unravel genetic contributions to immune-mediated traits, with a focus on the major histocompatibility complex (MHC) region. His work leverages large biobank datasets (UK Biobank, Biobank Japan), gene expression resources (GTEx), and proteomic data to decode molecular mechanisms linking genetic variation to disease risk. Specific interests include tuberculosis genetics, multi-ancestry polygenic risk scores, and single-cell eQTL modeling. Recent publications highlight expertise in HLA association studies, evolutionary immunogenetics, and disease-specific cell state dynamics. Key contributions include constructing a global HLA haplotype panel and developing novel statistical methods for admixed population genetics. Scientific Awards: Kennedy Trust Senior Research Fellow in Data Science His lab integrates computational and experimental approaches to translate genetic findings into clinical applications for immune disorders.
Jeremy Wang, PhD is an Assistant Professor in the Department of Genetics at the UNC School of Medicine . His research focuses on applying high-performance computational methods and machine learning to analyze high-throughput sequence data using long-read technologies (e.g., Oxford Nanopore) to advance precision personalized medicine . Key disease areas include Inflammatory Bowel Diseases (IBD) Respiratory Infectious Diseases His lab specializes in microbiome analysis , host-pathogen interactions , and computational genomics , working with collaborators in clinical, translational, and computational domains. His publications demonstrate expertise in long-read sequencing applications for Pediatric cancer classification SARS-CoV-2 genomic epidemiology Microbiome spatiotemporal dynamics Murine disease models Drosophilid genome assemblies Metagenomic bias analysis Collaborations span UNC and global institutions, with current work extending to clinical laboratory partnerships for pathogen sequencing and oral microbiome sampling methodology.
Ketika Garg is a Postdoctoral Scholar Research Associate in the Division of the Humanities and Social Sciences at the California Institute of Technology (Caltech), with an office in the Broad Center for Biological Sciences. Her research focuses on the interplay between individual and social decisions, using experimental and computational methods to explore how social environments influence decision-making and collective behavior. She investigates contexts ranging from traditional foraging paradigms to modern social media landscapes, developing innovative experimental frameworks to study these dynamics. Her research interests span computational neuroscience, social media analysis, and collective behavior, with a particular emphasis on understanding exploration-exploitation trade-offs in both natural and digital environments. She has contributed to studies on hunter-gatherer foraging networks, online toxicity dynamics, and the evolution of search strategies in collective foraging systems. Her work bridges disciplines such as psychology, ecology, and computer science to address fundamental questions in decision-making and social interaction. Dr. Garg’s publications reflect her interdisciplinary approach, covering topics like synergy in collective problem-solving, the roots of online toxicity, and the application of Lévy walks in virtual foraging experiments. While no formal awards or grants are explicitly listed in the provided materials, her research trajectory demonstrates a commitment to advancing methodologies in computational social science. Contact: kgarg@caltech.edu Office: Broad Center for Biological Sciences (96) Phone: 626-395-1755
Max Alekseyev is an Associate Professor in the Mathematics Department and Computational Biology Institute. His research spans computational graph theory, enumerative combinatorics, computational/algorithmic biology, and comparative genomics. He focuses on interdisciplinary problems, blending mathematics with biological applications, particularly in genome assembly and analysis. His work includes advancements in genome scaffolding algorithms, combinatorial sequence analysis, and mathematical biology. Notable contributions involve genome assembly tools like CAMSA and studies on ancestral genome reconstruction. He also explores theoretical topics such as Bernoulli series generalizations and modular data classification. His research trends highlight a blend of pure mathematics (e.g., number theory, graph theory) and applied computational methods, addressing challenges in genomics and evolutionary biology. He secured an NSF Student Travel Grant in 2018 for computational molecular biology.
Associate Professor Colin Jackson is affiliated with the Research School of Chemistry at the Australian National University College of Physical & Mathematical Sciences . His research spans enzyme engineering, synthetic biology, and protein evolution, with a focus on directed evolution approaches for biocatalysis and molecular biophysics. Former CSIRO and Weizmann Institute researcher Key projects: plastic degradation enzymes, viral protease inhibitors, noncanonical amino acid incorporation His work leverages ancestral sequence reconstruction and machine learning to explore protein sequence spaces, with notable outputs in fitness landscape analysis and biocatalytic applications . Recent publications highlight advancements in: Plastic biodegradation enzyme engineering Antiviral peptide design targeting SARS-CoV-2 Fluorinated noncanonical amino acids for protein studies Marine bacterial transport proteins Organophosphate resistance mechanisms While no formal awards are listed in this data, his research portfolio demonstrates strong industry and biomedical applications through: ANU Researcher Portal publications Collaborative projects with international institutions 50+ funded projects including gene therapy platforms and food waste solutions
Matteo Bolner is a Post-Doctoral Research Fellow at the University of Bologna's Department of Agricultural and Food Sciences, specializing in livestock genomics and metabolomics. He holds a PhD in Agricultural and Food Sciences (defended March 2025) and an International Master in Bioinformatics from the University of Bologna. His research integrates genomic and metabolomic data to improve livestock sustainability, particularly in pig production systems. Key focuses include identifying metabolic pathways influencing production traits, analyzing pig viromes for disease outbreaks, and leveraging big data for One Health applications. His educational background includes a Biological Sciences degree (2018) and a bioinformatics master's (2021). He interned at CINECA's SCAI department, focusing on HPC software containerization. Current affiliations include membership in the Animal and Food Genomics group, where he explores genomic solutions for breed conservation and sustainable production. Research trends in his articles emphasize multi-omics integration to understand pig metabolism, stress responses, and breed-specific adaptations. He also applies genomics to authenticate food products and enhance conservation strategies for endangered livestock breeds like the Mora Romagnola pig. His work bridges animal science, computational biology, and agricultural sustainability. Notable contributions include developing genomic tools for honey bee population analysis and creating a catalog of mitochondrial insertions in pig genomes. Future directions involve advancing metabolomics-based precision livestock farming and applying big data analytics to livestock One Health challenges.
Istvan Albert is a Research Professor of Bioinformatics at Pennsylvania State University , affiliated with the Department of Biochemistry and Molecular Biology . He leads the Bioinformatics Consulting Center and teaches BMMB 852: Applied Bioinformatics . Research Interests: Specializing in bioinformatics, large-scale biological data analysis, microarray and sequence analysis, scientific programming, algorithm development, and database-driven web development. His work spans gene ontology visualization , RNA-Seq analysis , and coronavirus research . Software Development: Created GeneScape for gene function visualization and bio for bioinformatics workflows. Maintains the Biostar Handbook series and the Biostars Q&A Forum , a leading bioinformatics resource.
Professor Mirko Trajkovski leads the Laboratory of Metabolic Diseases at the Faculty of Medicine, University of Geneva. He completed his PhD at the International Max Planck School in Dresden (2005), followed by postdoctoral research at ETH Zurich, before establishing his lab at University College London (2012) and moving to Geneva (2013). His work focuses on adipose tissue plasticity , gut microbiota , and their roles in obesity , diabetes , and insulin resistance . Swiss National Science Foundation Professor (2014) ERC Starting Grant (2014) & Consolidator Grant (2019) Dr Walter Seipp Prize & Carl Gustav Carus Prize (2005) His lab investigates fat browning mechanisms , microbiota-host communication , and multi-tissue metabolic regulation using in vivo , in vitro , and human cohort approaches. Recent publications emphasize microbiome-based therapies , temperature effects on metabolism , and gut-bone-adipose crosstalk . Current advisees include PhD student Silas Kieser, with past members like Jing Xue, Salvatore Fabbiano, and Claire Chevalier contributing to immuno-metabolism and microbial engineering projects.
Colin Cooper is a Professor of Cancer Genetics at the Norwich Medical School, University of East Anglia. He is also a member of the Metabolic Health and Cancer Studies research groups. His work focuses on genomic evolution, tumor microbiome dynamics, and biomarker development for prostate cancer and musculoskeletal health. Cooper’s recent research explores the interplay between cancer genetics and microbial communities, emphasizing their role in prognosis and treatment outcomes. He investigates clonal evolution in tumors, mutational signatures, and non-invasive diagnostic tools like urinary extracellular vesicles. His collaborations span genomics, microbiology, and clinical applications. 2025: Causes of evolutionary divergence in prostate cancer (Genomics, Precision Medicine) 2024: Applications of urinary extracellular vesicles... (Biomarker Development, Liquid Biopsy) 2023: Caution regarding pan-cancer microbial structure (Methodological Considerations, Microbiome Analysis) In 2022, Cooper received the European Urology Oncology SoMe Award for his contributions. His work is frequently cited and has been featured in media outlets globally, highlighting his impact on cancer and aging research.
Maria Chikina is an Assistant Professor at the University of Pittsburgh School of Medicine's Department of Computational and Systems Biology. She holds a PhD in Molecular Biology from Princeton University. Her research focuses on developing computational methods to analyze large-scale genomic datasets, bridging statistical rigor with biological insights to overcome experimental biases. Key research areas include latent variable modeling (e.g., PLIER, CellCODE), interpretable neural networks for sequence-to-function modeling, evolutionary rate analysis (RERconverge), and applications in tumor immunology, exercise genomics, and infectious disease (e.g., SARS-CoV-2). Her lab has developed tools like InstaPrism, NIFA, and L0 segmentation for data-driven biological discovery. Her work spans collaborations with institutions like UPMC (on tumor microenvironment) and the Molecular Transducers of Physical Activity Consortium (MoTraPAC). Notable projects include analyzing convergent evolution in marine mammals and subterranean species, and developing epigenetic biomarkers for disease states through the ECHO program. Lab members include PhD students (Rezwan Hosseini, Tugrul Balci) and postdocs (Tina Subic, Anish Sevekari). Past students Wynn Meyer now leads a group at Lehigh University. Her group emphasizes open-source tools (GitHub repository ChikinaLab) and interdisciplinary approaches to systems biology challenges.
Akihiko Nishimura is an Assistant Professor in the Department of Biostatistics at the Johns Hopkins Bloomberg School of Public Health. He holds a PhD from Duke University (2017) and MS and BS degrees from Stanford University (2011 and 2010). His research focuses on Bayesian methods, statistical computing, and public health data science, with applications in precision medicine and observational health data analytics. PhD, Duke University, 2017 MS, Stanford University, 2011 BS, Stanford University, 2010 Nishimura's research centers on developing advanced statistical and computational methodologies for real-world health data. His work emphasizes Bayesian inference, large-scale computing, and software development for reproducible research. He is particularly interested in using observational health data to improve clinical decision-making and advance precision medicine. He co-leads the Bayesian Learning and Spatio-Temporal modeling group (BLAST Group) and the inHealth/OHDSI Lab , collaborating with clinicians and data scientists across institutions. His recent publications reflect a strong trend in methodological innovation in Monte Carlo methods (e.g., Hamiltonian and Zigzag samplers), scalable Bayesian inference, and applications in pharmacovigilance, diabetes management, and infectious disease modeling. The articles span disciplines including biostatistics, computational statistics, public health, and bioinformatics, demonstrating a consistent focus on high-impact, computationally intensive problems in health data science. Nishimura actively contributes to the scientific community through methodological development and open science. He develops statistical software and shares teaching materials on GitHub, emphasizing reproducibility and performant computing. His involvement in the OHDSI community enables large-scale, multi-institutional studies that would not be feasible with single-source data. His work has been recognized through publications in top-tier journals such as the Journal of the American Statistical Association , Biometrika , and JAMA Ophthalmology , and has been picked up by numerous news outlets and social media platforms, indicating broad scientific and public impact. Nishimura teaches courses on performant statistical computing and advanced Monte Carlo methods, training the next generation of data scientists in efficient algorithm and software design. He mentors students and collaborators in statistical methodology and software development, fostering a culture of rigorous, reproducible, and impactful research.
Mark Eppinger, Ph.D., is an Associate Professor in the Department of Molecular Microbiology and Immunology at The University of Texas at San Antonio (UTSA), within the College of Sciences. His research is centered on microbial genomics and bioinformatics, with a focus on understanding infectious diseases caused by bacterial pathogens such as Yersinia pestis , Vibrio cholerae , and Escherichia coli O157:H7. Department: Molecular Microbiology and Immunology School: College of Sciences University: The University of Texas at San Antonio Email: Mark.Eppinger@utsa.edu Phone: 210-458-6276 Lab: BSE 3.404 Dr. Eppinger earned his Ph.D. in Microbial Genetics from the Max-Planck Institute for Developmental Biology and the University of Tübingen, Germany, and a B.S. in Biology from the same institution. Ph.D. in Microbial Genetics, Max-Planck Institute for Developmental Biology, University of Tübingen B.S. in Biology, University of Tübingen His research program applies microbial genomics and bioinformatics to investigate the evolutionary and ecological dynamics of bacterial pathogens. He focuses on phylogenomics, genome plasticity, virulence determinants, and host-pathogen interactions. His lab generates genomic data to understand how genetic variation influences transmissibility, infectivity, and disease outcomes in major public health threats. The available publications reflect a consistent focus on the genomics of foodborne and epidemic bacterial pathogens. Both book chapters deal with the genomic analysis of Escherichia coli and Yersinia , emphasizing evolutionary patterns, virulence mechanisms, and molecular epidemiology. These works highlight his expertise in integrating genomic data with public health applications. Dr. Eppinger has mentored a wide range of students, including doctoral candidates, postdoctoral researchers, master's students, and undergraduates. His lab has hosted international exchange students and Fulbright Fellows, indicating a collaborative and globally engaged research environment. He leads the Eppinger Lab at UTSA, which is part of the South Texas Center for Emerging Infectious Diseases (STCEID). The lab conducts cutting-edge genomic research on emerging pathogens and contributes to the development of diagnostic and therapeutic strategies to reduce human morbidity.
Rachel Sippy is a Research Fellow at the University of Cambridge , specializing in epidemiology and infectious disease dynamics within the Department of Psychiatry . Her work bridges public health, climate science, and computational methods.
