جستجوی استاد راهنمای دانشگاهی

Andre Levchenkoمشاهده پروفایل

استاد

• Systems Biology
• Signal Transduction
• Cell Communication
• +۵ مورد دیگر

Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

Sara Galliniمشاهده پروفایل

استادیار

• Cancer Biology
• Cellular Dynamics
• Epithelial Biology
• +۳ مورد دیگر

Sara Gallini is an Assistant Professor at EPFL, leading the Gallini Lab within the ISREC Department of the School of Engineering (SV). Her research focuses on understanding how healthy and oncogenic cells compete in skin epithelium, aiming to identify therapeutic targets for skin cancer prevention. She holds a Tenure Track position and teaches in the Life Sciences Engineering program. Her lab employs advanced in vivo imaging and single-cell analysis techniques. Education details are not explicitly provided, but her career includes a postdoctoral fellowship with the HFSP. Her research integrates molecular, cellular, and systems-level approaches to study cancer initiation and tissue homeostasis, particularly in injury-driven dynamics. Lab Members: Includes PhD student Mustafa Öztürk and technical staff Mélanie Sipion. Key Research Themes: Oncogenic cell competition, epidermal regeneration, EGFR/ERK signaling, and therapeutic target discovery. Her lab collaborates with clinical teams and uses models like mouse skin to study tumor suppression mechanisms. Future work aims to leverage healthy cell dynamics for cancer treatment strategies. Contact: SV 2527 office, +41216936764, sara.gallini@epfl.ch .

Andrea Liuمشاهده پروفایل

استاد

• Theoretical Soft Matter
• Living Matter Physics
• Glass Transition
• +۴ مورد دیگر

Andrea Liu is the Hepburn Professor of Physics at the University of Pennsylvania, leading the Department of Physics and Astronomy. As Director of the Penn Center for Soft and Living Matter, she bridges physics, biology, and materials science. She joined Penn in 2004 after faculty roles at UCLA (1994-2004) and postdoctoral research at Exxon and UCSB. Her research focuses on theoretical studies of soft and living matter, particularly jamming transitions, glass physics, and emergent phenomena in biological systems. She pioneers the application of machine learning to physical systems, designing self-learning materials and circuits. Education Ph.D., Cornell University (1989) B.A., University of California, Berkeley (1984) Research Interests Soft matter: Glass transition, jamming, and plasticity in disordered solids Living matter: Collective behavior in tissues, fluidization mechanisms, and biopolymer networks Machine learning: Physical implementations, energy-efficient circuits, and adaptive systems Her work combines analytical theory and computation to explain how complex systems achieve functionality through structural and dynamical principles. Publications Trends Recent work emphasizes physical learning networks, clogging dynamics in granular systems, and biophysical tissue mechanics. Key themes include emergent learning in analog systems, topology-driven material design, and interdisciplinary approaches to biological and engineering challenges. Awards 2025 American Physical Society Leo P. Kadanoff Prize 2021-2025 Simons Investigator in Theoretical Physics Member, National Academy of Sciences (2017) Labs & Teams Her research group collaborates on the Center for Soft and Living Matter, advancing theoretical frameworks for adaptive materials and biological systems. Ongoing initiatives focus on machine learning-informed materials design and experimental validation of theoretical models.

Omer Bayraktarمشاهده پروفایل

پژوهشگر

• Neural Diversity
• Spatial Transcriptomics
• Glia Biology
• +۳ مورد دیگر

Omer Bayraktar is a Group Leader at the Wellcome Sanger Institute , leading research in the Cellular Genomics Programme. His work focuses on decoding human brain cellular diversity using spatial transcriptomics , imaging , and functional screening to study neural complexity in health and disease. Bayraktar's educational background includes a PhD from HHMI under Chris Doe, investigating neural diversity development in Drosophila , followed by postdoctoral work at University of California, San Francisco and University of Cambridge as a Life Sciences Research Foundation Fellow. He developed a spatial transcriptomic pipeline during his postdoc to analyze astrocyte heterogeneity in the cerebral cortex. His research explores neural cell type mapping , glial-neuronal interactions , and cellular pathways in neurodevelopmental disorders . Recent publications emphasize 3D tissue mapping , multi-omic integration , and computational tools like Cell2fate and WebAtlas. His work bridges neurogenetics and computational biology to advance understanding of human tissue ecosystems. Bayraktar's lab collaborates with the Human Cell Atlas initiative and develops technologies such as automated histology pipelines and highly-multiplexed smFISH for molecular cell typing. His team also investigates glia-based therapies and astrocyte functional heterogeneity in neurodevelopmental contexts. Key scientific contributions include: Discovering astrocyte layer patterns independent of neuronal laminae Developing cell2location for spatial cell mapping Characterizing Drosophila neural stem cell models with human relevance Notable awards include the Life Sciences Research Foundation Fellowship during his postdoctoral training. His current group includes a PhD student , Senior Data Scientists , and Bioinformaticians .

Ovijit Chaudhuriمشاهده پروفایل

دانشیار

• Mechanobiology
• Cellular Mechanics
• Extracellular Matrix
• +۵ مورد دیگر

Ovijit Chaudhuri is an Associate Professor of Mechanical Engineering at Stanford University, with a courtesy appointment in Bioengineering. He leads research at the interface of mechanics and biology, focusing on how cellular and extracellular mechanical properties influence biological processes like cancer progression and tissue formation. His work employs advanced tools such as atomic force microscopy and 3D cell culture systems. Education: Ph.D., University of California, Berkeley/San Francisco (Bioengineering, 2009) B.S., University of California, Berkeley (Engineering Physics, 2003) Postdoctoral Fellow, Harvard University (Biomaterials, 2013) Research Interests: His lab explores molecular mechanisms behind cellular mechanics, extracellular matrix dynamics, and how mechanical cues regulate cell behavior. Key areas include cancer metastasis, mechanotransduction, and engineered biomaterials for 3D cell culture. Publications Trends: Recent work emphasizes viscoelastic hydrogels, matrix mechanics in cancer progression, and mechanistic insights into cell migration. Over 50 publications since 2015 highlight interdisciplinary approaches in biomaterials and mechanobiology. Awards: Not explicitly listed in provided materials. Advising & Labs: No specific advisee names listed, but his lab focuses on collaborative projects in mechano-biology. Active in developing biomaterial systems for drug discovery and tissue engineering applications. Labs/Teams: Leads the Chaudhuri Lab at Stanford, which integrates engineering principles with biological systems to address complex disease mechanisms and therapeutic strategies.

Andreas Bauschمشاهده پروفایل

استاد

• Cellular Biophysics
• Molecular Biophysics
• Structural Biology
• +۶ مورد دیگر

Prof. Andreas Bausch holds the Heinz Nixdorf Endowed Chair of Cell Biophysics at the Technical University of Munich (TUM) within the TUM School of Natural Sciences . His research focuses on cellular biophysics , particularly the mechanical properties of cytoskeletal networks and self-organization mechanisms in biological systems, with applications in biomimetic materials and organoid modeling. Research Areas : Cytoskeletal mechanics, active matter systems, organoid morphogenesis, integrin signaling, synthetic cell models Techniques : Microrheology, in vitro reconstitution, microfluidics, advanced imaging His work has produced over 100 publications in Nature, Science, PNAS , and Physical Review Letters , with recent emphasis on pancreatic cancer organoids and artificial cell membranes . Key findings include: Discovery of topological excitations governing endothelial cell ordering Elucidation of PIP2/PIP3 regulation in integrin phase separation Development of 3D patterned organoid systems for drug screening Major awards include: ERC Synergy Grant (2018) ERC Advanced Grant (2012) ERC Starting Grant (2011) Berlin-Brandenburg Academy of Sciences Prize (2014) He serves as founding director of the Center for Functional Protein Assemblies (CPA) since 2015 and teaches biomechanics , biophysics , and protein assemblies at TUM. His lab investigates both fundamental biophysical principles and their medical applications in cancer and cardiovascular systems.

Kara McKinleyمشاهده پروفایل

استادیار

• Regenerative Medicine
• Reproductive Biology
• Cell Biology
• +۹ مورد دیگر

Kara McKinley is an Assistant Professor of Stem Cell and Regenerative Biology at Harvard University , joining the department in 2021. She is a Principal Faculty member at the Harvard Stem Cell Institute , an Associate member of the Broad Institute of MIT and Harvard , and a Freeman Hrabowski Scholar at the Howard Hughes Medical Institute . Her research focuses on the regenerative capacity of the human uterus , particularly the endometrium, which undergoes ~400 cycles of tissue remodeling, shedding, and repair during the reproductive lifespan. Using rodent models , genetic, molecular, and live microscopy tools, her lab investigates cellular and molecular mechanisms of regeneration, defects leading to diseases like endometriosis, and applications in regenerative medicine . Her work also explores cell division , centromere biology , and CRISPR genome engineering . Current research trends in her publications include epithelial zonation in the small intestine , mechanisms of endometrial regeneration , macropinocytosis in Hydra , and academic mentorship strategies . Her studies span cellular biomechanics , mitotic regulation , and translational approaches for tissue repair. NIH Director’s New Innovator Award (terminated in 2025 litigation with federal government) Freeman Hrabowski Scholar (Broad Institute) Kara mentors Harvard undergraduates, graduate students, and postdoctoral fellows through rotations and research opportunities. Her lab is based at Harvard’s Bauer 306 and advocates for gender equity in life sciences faculty via the Leading Edge initiative. Funding includes a now-terminated NIH New Innovator grant aimed at menstrual health research.

Sudin Bhattacharyaمشاهده پروفایل

دانشیار

• Systems Toxicology
• Computational Biology
• Gene Expression Analysis
• +۳ مورد دیگر

Sudin Bhattacharya is an Associate Professor at the BioMolecular Science Gateway, Michigan State University, with affiliations in the Genetics & Genome Sciences Program and Cell & Molecular Biology Program. His research bridges computational biology and toxicology to understand complex biological systems. Email: sbhattac@msu.edu Research Interests Dr. Bhattacharya specializes in systems toxicology, focusing on computational modeling of gene regulatory networks, single-cell transcriptomics, and molecular dynamics in response to environmental toxicants. His work examines how chemical exposures disrupt cellular pathways and contribute to disease mechanisms. Article Trends His recent publications emphasize: Single-cell and single-nucleus RNA sequencing for toxicological profiling Computational models of circadian rhythms and intercellular communication Dose-dependent responses to environmental chemicals like TCDD and heavy metals Mechanistic studies of adipose tissue remodeling and hypertension Applications of machine learning in chemical risk assessment Integrative approaches to liver metabolism and disease modeling Scientific Contributions Dr. Bhattacharya has pioneered multiscale modeling of biological systems, particularly in hepatic and vascular contexts. His work on the aryl hydrocarbon receptor and PPARα signaling networks has advanced predictive toxicology frameworks.

Charlotte Kuperwasserمشاهده پروفایل

استاد

• Breast Cancer Research
• Mammary Gland Biology
• Cancer Prevention
• +۴ مورد دیگر

Dr. Charlotte Kuperwasser is a distinguished Professor in the Department of Developmental, Molecular, and Chemical Biology at Tufts University School of Medicine . She directs the Tufts Convergence Laboratory and focuses on molecular mechanisms governing breast tissue development, cancer prevention, and organoid technologies. Her work integrates stem cell biology, epigenetics, and environmental influences such as endocrine disruptors. Education: Bachelor of Science (1997), University of Massachusetts Amherst PhD (2000), University of Massachusetts Amherst Jane Coffin Childs Postdoctoral Fellow (MIT/Whitehead Institute) Research Interests: Her lab develops 3D breast organoid models to study cancer initiation, microenvironmental interactions, and BRCA1-related mechanisms. Recent efforts include analyzing HPV-driven cancers via circulating tumor DNA and studying fibroblast signaling (e.g., DDR1) in tumor progression. Grants & Awards: Howard Hughes Fellowship, Merck Fellowship COG/Aventis Young Investigator Award Natalie V. Zucker Award NIH grants on V-ATPases and obesity-cancer links Professional Contributions: She chairs Tufts’ Sackler Convergence Laboratory and serves on AACR committees. Teaching includes courses on Molecular Cell Biology of Development and Cancer Genetics . Labs/Teams: Leads the Kuperwasser Lab, focusing on translational cancer research with cross-disciplinary collaborations in organoid engineering and clinical diagnostics.

Jessica E. Treismanمشاهده پروفایل

استاد

• Developmental genetics
• Cell signaling
• Synapse formation
• +۵ مورد دیگر

Jessica E. Treisman is a Professor in the Department of Cell Biology and Department of Ophthalmology at NYU Grossman School of Medicine. Her research focuses on developmental genetics and molecular neuroscience, particularly in the context of visual system development and synapse formation in Drosophila . Research Interests: Cell fate determination, tissue morphogenesis, neural circuit assembly, and corneal lens development Contact: Jessica.Treisman@nyulangone.org | 212-263-1031 Lab: Treisman Lab, Skirball Institute, New York, NY Her work explores how intrinsic transcription factors and extrinsic signaling pathways interact to regulate cell differentiation and tissue organization in the Drosophila visual system, with implications for understanding human corneal development and neural connectivity disorders. Recent publications highlight her contributions to understanding: Molecular mechanisms of corneal lens curvature formation Regulation of synaptic targeting specificity Role of Sidekick in epithelial junction dynamics Transcriptional synergy between Glass and EGFR signaling The Treisman Lab employs interdisciplinary approaches in Drosophila genetics to uncover fundamental principles of cell signaling and neural circuit development, with potential applications in human vision research and developmental disorders.

Maja Matisمشاهده پروفایل

پژوهشگر

• Cell Biology
• Developmental Biology
• Biophysics
• +۳ مورد دیگر

Dr. Maja Matis is a Group Leader at the University of Muenster's Center for Molecular Biology of Inflammation (ZMBE) within the Institute of Cell Biology. Her research focuses on understanding the mechanical role of microtubules in tissue morphogenesis, particularly how microtubule-generated forces contribute to tissue remodeling through coordinated cellular behaviors. She leads the Matis Lab, which employs advanced microscopy techniques and genetic approaches to study cytoskeletal mechanics in developmental contexts. Key research areas include the structural regulation of microtubules, mechanics-driven cell shape changes, and integration of forces at adherens junctions. Her interdisciplinary projects combine biophysics, developmental biology, and quantitative imaging to unravel mechanisms underlying collective cell behavior during tissue formation. Notable contributions include studies on microtubule compression dynamics in epithelial tissues and the role of PCP signaling in patterning microtubule networks. She collaborates with institutions like the Cells in Motion Cluster of Excellence and has mentored multiple PhD/MD students. Her work is published in high-impact journals such as Nat. Commun. and Nat. Cell Biol.

• Organoid Engineering
• Systems Biology
• Developmental Biology
• +۳ مورد دیگر

Keisuke Ishihara is an Assistant Professor in the Department of Computational and Systems Biology at the University of Pittsburgh School of Medicine. His research focuses on engineering human brain and cardiac organoids using genetic, chemical, and computational approaches to uncover novel regulatory mechanisms and physical principles underlying tissue development. His lab is located at Biomedical Science Tower 3, with an office in room 10020A. Dr. Ishihara holds a PhD in Systems Biology from Harvard University. His work bridges synthetic biology, developmental biology, and biophysics to address fundamental questions in organogenesis and cellular morphogenesis. Recent research highlights include studies on BMP-mediated neural tube patterning in organoids and the biophysical dynamics of microtubule assemblies in large cells. Publications from his lab emphasize interdisciplinary approaches to understand cell size scaling, mitotic spindle dynamics, and self-organization in synthetic tissues. His team has contributed to advancements in organoid technology, uncovering dormant genetic programs and physical principles governing tissue architecture. Laboratory activities are centered at the University of Pittsburgh, collaborating with the School of Medicine's computational and systems biology initiatives. For more details, visit his lab website linked below.

Andrés J. Garcíaمشاهده پروفایل

استاد

• Bioengineering
• Regenerative Medicine
• Biomaterials
• +۷ مورد دیگر

Andrés J. García is the Executive Director of the Parker H. Petit Institute for Bioengineering & Bioscience and a Regents’ Professor in the George Woodruff School of Mechanical Engineering at Georgia Institute of Technology. His research focuses on engineered biomaterials for regenerative medicine, including tissue repair, inflammation modulation, and cell adhesion mechanisms. He co-founded three startups (CellectCell, CorAmi Therapeutics, iTolerance) and holds multiple patents in biomaterials and drug delivery systems. Education: Ph.D., University of Pennsylvania, 1996 M.S.E., University of Pennsylvania, 1992 B.S., Cornell University, 1991 Research Interests: García’s work integrates engineering, materials science, and cell biology to develop biomaterials that direct cellular responses. Key areas include: Biomaterial platforms for bone repair and vascularization Immunomodulatory hydrogels for islet transplantation Antibacterial hydrogels for implant infection control Organoid generation using synthetic hydrogels Mechanisms of cell adhesion and mechanotransduction Publications: Over 30+ peer-reviewed articles in Nature Communications , Science Advances , Biomaterials , and others, highlighting innovations in hydrogel design, stem cell therapies, and biomaterial-driven tissue repair. Awards: Member of both the National Academy of Engineering and National Academy of Medicine (2021), Clemson Award for Basic Research (2012), and Fellowships with the American Society of Mechanical Engineers and AAAS. Labs/Teams: Leads the García Laboratory, collaborating across disciplines to translate biomaterials research into clinical applications. Active in startup partnerships and federal grants (e.g., NSF, NIH).

Ben Allenمشاهده پروفایل

دانشیار

• Hedgehog Signaling
• Developmental Biology
• Signal Transduction Pathways
• +۳ مورد دیگر

Ben Allen is an Associate Professor in the Department of Cell and Developmental Biology at the University of Michigan. His research focuses on the mechanisms of growth factor and morphogen signaling, particularly Hedgehog (HH) signaling in development, tissue homeostasis, and cancer. Employing techniques such as mouse genetics, chicken in ovo electroporations, and biochemical analyses, his lab investigates HH signaling regulation in embryonic/postnatal development and diseases like pancreatic cancer. Recent work explores HH pathway roles in taste organ repair, kidney morphogenesis, and immunosuppressive tumor microenvironments. The lab's publications highlight interdisciplinary approaches, with keywords spanning developmental biology, cancer biology, and signal transduction. Subfields include pancreatic cancer progression, ciliary transport, GLI transcription factor dynamics, and tissue-specific signaling modulation. Collaborations with cancer researchers and regenerative medicine specialists are evident. Allen's group also contributes to science education initiatives, exemplified by their "Developing Future Biologists" program targeting underrepresented undergraduate students.

Jianping Fuمشاهده پروفایل

استاد

• Stem Cell Bioengineering
• Developmental Bioengineering
• Mechanobiology
• +۴ مورد دیگر

Jianping Fu is a Professor in the Department of Mechanical Engineering at the University of Michigan , with joint appointments in Biomedical Engineering and Cell and Developmental Biology. His research integrates micro/nanoengineering , mechanobiology , and stem cell biology to model human development and disease. Education: PhD (MIT, 2007), BE (University of Science and Technology of China, 2000) His research interests focus on stem cell bioengineering , developmental bioengineering , and mechanobiology , particularly in modeling early post-implantation human development, neural tube formation, and pluripotent stem cell mechanoregulation. His work combines biomimetic culture systems with microfluidic gradients to study embryogenesis and organogenesis. Recent publications highlight advances in human embryo modeling (2024 Cell, Nature, Cell Stem Cell), neural tube patterning (2024 Nature), and mechanobiology of stem cells (2024 Nature Reviews Physics). These studies emphasize computational methods , single-cell analysis , and standardization of embryo models . Scientific honors include: Friedrich Wilhelm Bessel Research Award (2022) ISSCR Merit Award (2024) Fellow, American Institute for Medical and Biological Engineering (2019) NSF CAREER Award (2012) Life Member, World Association of Chinese Biomedical Engineers (2024) Dr. Fu mentors extensively, with 20+ alumni including PhD students and postdocs now in academic and industry positions. His lab has received $3M NIH funding for immunological diagnostics and MTRAC grants for translational research. Collaborations with institutions like Cincinnati Children's Hospital and Rice University enhance his interdisciplinary approach to regenerative medicine.