جست‌وجوی استاد و پژوهشگر

Effie Apostolouمشاهده پروفایل

دانشیار

• 3D Chromatin Architecture
• Epigenetics
• Cell Fate Reprogramming
• +۵ مورد دیگر

Effie Apostolou serves as Associate Professor of Molecular Biology in Medicine at Weill Cornell Medicine's Department of Medicine, Division of Hematology/Oncology and Cancer Center. She leads the Chromatin Organization & Cell Fate Decisions laboratory within the vibrant Tri-Institutional research community (Weill Cornell, Rockefeller University, Memorial Sloan Kettering). Her research focuses on the critical interplay between transcription factors, 3D chromatin architecture, and transcriptional regulation during cell fate decisions. Key areas include somatic cell reprogramming to induced pluripotent stem cells (iPSCs), epigenetic inheritance of cell identity, and dysregulation in cancer. Her lab utilizes cutting-edge 4D genomics approaches including Hi-C, ChIP-seq, and CRISPR-based technologies to build molecular roadmaps of cellular transitions. Analysis of her publication record reveals consistent focus on chromatin topology mechanisms across developmental and disease contexts. Her work spans fundamental discoveries in mitotic bookmarking (2021), enhancer-promoter networks (2019), and epigenetic barriers to reprogramming (2012-2013), demonstrating interdisciplinary integration of computational and experimental genomics. Scientific recognition includes: NIH Director's New Innovator Award Emerging Leader Award from the Mark Foundation EMBO Postdoctoral Fellowship Jane Coffins Child Foundation Fellowship As a dedicated mentor, she advises multiple PhD students across BCMB, PBSB, and Tri-I CBM programs while maintaining a multicultural lab environment with members from over 10 nationalities. Her research is supported through the 4D Nucleome Consortium and focuses on translating chromatin architecture insights into therapeutic applications for cancer and regenerative medicine.

Ian Hendersonمشاهده پروفایل

استاد

• Genetics
• Epigenetics
• Meiosis
• +۴ مورد دیگر

Professor Ian Henderson is a leading academic in the Department of Plant Sciences at the University of Cambridge, affiliated with the School of Biological Sciences. He holds the title of Professor of Genetics and Epigenetics and has been a Royal Society University Research Fellow and Gatsby Resident Fellow since 2008. Education: BA in Biological Sciences (University of Oxford, 1997-2000); PhD in Plant Genetics (John Innes Centre, 2000-2004) under Prof. Caroline Dean His research focuses on genetic and epigenetic control of meiotic recombination in plant genomes, with an emphasis on crossover frequency, chromatin interactions, and centromere evolution. His group uses model organisms like Arabidopsis thaliana , wheat, potato, and oak trees. Key trends in his recent publications include centromere genomics , epigenetic regulation of recombination , and application of long-read sequencing to resolve complex genomic regions. Collaborations with agro-biotech companies (Bayer Biosciences, Solynta) aim to translate findings into crop breeding technologies. Scientific Awards EMBO Member (2022) Society for Experimental Biology President's Medal (2013) Royal Society University Research Fellow (2008-2016) Gatsby Research Fellow (2008-2016) EMBO Long Term Fellowship (2004-2008) Professor Henderson's work bridges fundamental research on plant genome evolution with applied strategies to control recombination for climate-resilient crops. His lab employs advanced techniques including nanopore sequencing , ChIP , and high-performance computing for genome analysis.

Julie Ahringerمشاهده پروفایل

استاد

• Chromatin Regulation
• Epigenetics
• Genome Organization
• +۳ مورد دیگر

Julie Ahringer is Professor of Genetics and Genomics at the University of Cambridge and Director of the Wellcome Trust/Cancer Research UK Gurdon Institute. She leads a research group investigating chromatin structure and gene regulation using C. elegans as a model system. Her work integrates genomics, super-resolution microscopy, and computational approaches to understand epigenetic controls in development and disease. She holds fellowships from the Royal Society (FRS) and Academy of Medical Sciences (FMedSci). Research Focus: Her laboratory studies chromatin regulation mechanisms including heterochromatin formation, Polycomb domain function, genome architecture, and enhancer/promoter interactions. Key approaches include single-cell multiomics, high-throughput genomics, and super-resolution microscopy to analyze developmental trajectories. Research areas span: H3K27me3 domain formation and Polycomb repression Constitutive heterochromatin organization Regulatory element characterization 3D genome architecture via ARC-C technology Single-cell resolution developmental mapping Awards & Honors: Fellow of the Royal Society (FRS) Fellow of the Academy of Medical Sciences (FMedSci) Wellcome Senior Research Fellowship Academic Leadership: She mentors PhD students and postdoctoral researchers, with funding from Wellcome, MRC, and CRUK. Her lab develops open-source bioinformatics tools (VplotR, periodicDNA) and maintains the genome-wide C. elegans RNAi feeding library. Lab & Collaborations: The Ahringer Lab is based at the Gurdon Institute and collaborates widely on chromatin dynamics, nuclear organization, and developmental genomics projects across model organisms.

Wendy Robinsonمشاهده پروفایل

استاد

• Medical Genetics
• Epigenetics
• Fetal Development
• +۴ مورد دیگر

Wendy P. Robinson is a Professor in the Department of Medical Genetics at the University of British Columbia Faculty of Medicine , and a Senior Scientist at the BC Children’s Hospital Research Institute . She holds the CIHR Sex and Gender Science Chair . Research Interests: Genetics and epigenetics of early human development, placental function in pregnancy complications (fetal growth restriction, preterm birth), DNA methylation, non-coding RNA, sex differences, and polymorphisms. Her lab employs genomic and bioinformatic tools to study placental health and its impact on newborn outcomes. Recent Publications (2025-2024) focus on X-chromosome inactivation patterns in placenta, cell-type specific DNA methylation, maternal socioeconomic effects on placental epigenetics, and modeling placental development with organoids. Key themes include sex-specific epigenetic regulation , maternal-fetal interactions , and human placental methylome . Awards: UBC Faculty of Medicine Distinguished Achievement Award (2018), with trainees receiving the James Miller Memorial Prize and Mary-Jane Carroll Trainee Award. Students & Collaborations: Supervised PhD/MSc students include Li Qing Wang, Icíar Fernández Boyano, Giulia Del Gobbo, Victor Yuan, and Magda Price. Collaborators span the Alex Beristain Lab and University of Toronto institutions. Laboratory Activities: Regular team-building events like mountain hikes, climbing outings, and kayaking trips, alongside providing open access to epigenetic tools (e.g., Bisearch, SeqDoc) for the research community.

• Plant Genetics
• Crop Biodiversity
• Breeding Informatics
• +۵ مورد دیگر

Karl Schmid is a W3 Professor of Crop Plant Biodiversity and Breeding Informatics at the University of Hohenheim's Institute of Plant Breeding, Seed Science and Population Genetics within the College of Agricultural Sciences. His research integrates evolutionary genetics, population genomics, and machine learning to address agricultural challenges. Ph.D. in Biology, University of Munich (1996) Postdoctoral Research, Cornell University (1997-1999) Emmy-Noether Research Group, Max Planck Institute of Chemical Ecology (2000-2006) Group Leader, Leibniz Institute of Plant Genetics (2006-2008) Professor of Genetics, Swedish Agricultural University (2008) His research focuses on crop biodiversity conservation, evolutionary genetics of plant pathogens, and breeding informatics applications. Current work leverages deep learning for phenotyping (quinoa panicles, barley genomics) and analyzes pathogen evolution (Exserohilum turcicum in maize). His team actively develops computational tools like GGoutlieR for geo-genetic pattern detection. Recent publications demonstrate strong trends in applying AI to agricultural genomics, particularly in quinoa improvement and pathogen surveillance. His group leads the EU H2020 INVITE project on molecular markers in plant variety protection and organizes international symposia like the 2024 Quinoa Symposium at Hohenheim. Head of Crop Biodiversity and Breeding Informatics Group Principal Investigator, EU H2020 INVITE project Organizer, International Quinoa Symposium 2024

W. Steven Wardمشاهده پروفایل

استاد

• Sperm Chromatin Structure
• Early Embryonic DNA Replication
• Biology of Early Folliculogenesis
• +۲ مورد دیگر

W. Steven Ward is a Professor and Director of the Institute for Biogenesis Research (IBR) at the John A. Burns School of Medicine, University of Hawaii. He holds dual affiliations with the Department of Anatomy, Biochemistry and Physiology and the Department of Obstetrics, Gynecology & Women's Health . Education: B.S. in Chemistry, American University of Beirut M.S. in Biochemistry, American University of Beirut Ph.D. in Biochemistry, Vanderbilt University (1985) Research Interests Dr. Ward's work focuses on chromatin structure during spermiogenesis and embryogenesis, particularly the organization of DNA in sperm cells. His lab developed a widely accepted model of sperm chromatin structure based on loop domains, which are critical for paternal DNA replication in embryos. Additional research explores ORC4 protein's role in chromatin expulsion during meiosis and erythrocyte maturation, alongside Exoc5's importance in folliculogenesis. Current projects span three areas: sperm chromatin structure, early embryonic DNA replication, and folliculogenesis biology. Publication Trends His 15 most recent articles (2023–1993) emphasize reproductive biology, developmental genetics, and molecular mechanisms of chromatin organization. Key themes include sperm DNA fragmentation, interspecies comparisons (hamster/mouse models), and the functional implications of chromatin expulsion in oocytes and red blood cells. Collaborative clinical research with urologists and geneticists is evident, particularly in studies linking chromatin structure to fertility outcomes. Grants & Leadership Dr. Ward has maintained continuous NIH funding since 1991 and led a $16M COBRE grant (2009–2025) to develop research capacity at the IBR. As Chief of the Obstetrics and Gynecology Division of Research (2014–), he bridges clinical and basic science, notably through studies on post-vasectomy DNA fragmentation and its developmental impacts. Labs & Teams As IBR director, he leads a multidisciplinary team investigating reproductive biogenesis, including spermatogenesis, oogenesis, and embryonic chromatin dynamics. The lab employs molecular, genetic, and clinical research approaches, often in collaboration with urology and obstetrics departments.

Katherine A. Hoadleyمشاهده پروفایل

دانشیار

• Cancer Genomics
• Breast Cancer Research
• Gene Expression Analysis
• +۳ مورد دیگر

Katherine A. Hoadley, PhD, is an Associate Professor in the Department of Genetics at UNC School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center. Her lab specializes in cancer biology through gene expression analyses and integrative genomic approaches , with a focus on breast cancer and pan-cancer projects. Key Affiliations : UNC Lineberger Comprehensive Cancer Center Computational Medicine Program Research Themes : Multi-omics cancer characterization Immune landscape mapping Proteogenomic therapeutic targeting Clinical trial genomic analysis Scientific Recognition : Clarivate Analytics Highly Cited Researcher (2018–2024) Breast Cancer Research Foundation Award (2020) Clinical Research Forum Awards (2015) Her work contributes to precision oncology through large-scale initiatives like The Cancer Genome Atlas (TCGA) and the Genomic Data Analysis Network (GDAN) , with applications in RNA sequencing analysis and clinical trial optimization .

• Male infertility
• Fertilisation
• Oocyte activation
• +۷ مورد دیگر

Kevin Coward is an Associate Professor at the University of Oxford's Nuffield Department of Women's and Reproductive Health (NDWRH), where he serves as Director of Taught Programmes and Lead for Testicular Cryopreservation Research. With expertise in reproductive physiology and endocrinology, he has directed the MSc in Clinical Embryology for 16 years and supervises numerous DPhil students in the fields of male infertility, fertilization mechanisms, and fertility preservation. Dr. Coward earned his BSc and PhD from the University of Stirling before holding post-doctoral positions at several prestigious London institutions. His educational background includes a Postgraduate Diploma in Learning & Teaching in Higher Education from Oxford, where he is a Senior Fellow of the Higher Education Academy and Fellow of the Royal Society of Biology. His research focuses on the molecular mechanisms of oocyte activation at fertilization, particularly the role of sperm-specific phospholipase C (PLCζ) in male infertility. His team investigates how PLCζ relates to conditions such as oocyte activation deficiency and total fertilization failure, while also developing nanoparticle- and exosome-mediated delivery systems for gametes and embryos. A significant aspect of his work involves fertility preservation strategies for prepubertal boys undergoing cancer treatment. Dr. Coward's recent publications demonstrate strong focus on male infertility research methodology, testicular tissue cryopreservation techniques, and the application of nanotechnology in reproductive medicine. His work shows increasing emphasis on developing standardized outcome measures for male infertility research and refining techniques for preserving fertility in young cancer patients. 2019 - Masters Teacher of the Year (FindAMasters and FindAPhD) 2018 & 2017 - Bronze Employer Award for STEM outreach 2018, 2014, 2013 - OxTALENT Awards for teaching innovation 2016 - Finalist, Royal Society of Biology Higher Education Bioscience Teacher of the Year 2015 - University Teaching Excellence Award and Nanoscience Research Leadership Award 2012 - University of Oxford Major Educator Teaching Excellence Award Dr. Coward has supervised 19 DPhil students to completion, 72 MSc students in laboratory settings, and numerous undergraduate and outreach students. His research group has secured funding from diverse sources including The Royal Society, Wellcome Trust, and European Commission. The group collaborates with clinical partners at Oxford University Hospitals NHS Foundation Trust on fertility preservation for young cancer patients. The Coward Research Group, based in the Nuffield Department of Women's and Reproductive Health, maintains active collaborations with The Fertility Partnership (Oxford), University of Dundee, University of Edinburgh, and industry partners like U-Ploid. The group regularly hosts school outreach activities and has won multiple awards for their STEM engagement efforts.

Timothy Bredyمشاهده پروفایل

دانشیار

• Epigenetics
• Fear-Related Memory
• RNA Biology
• +۶ مورد دیگر

Associate Professor Timothy Bredy is a leading figure in cognitive neuroepigenetics at the Queensland Brain Institute (QBI) , focusing on how epigenetic modifications and RNA dynamics regulate fear-related memory and psychiatric disorders like PTSD. His research explores the interplay between environmental experiences and genomic activity, particularly through non-coding RNA and DNA methylation. University: University of Queensland School: Faculty of Health, Medicine and Behavioural Sciences Role: Professorial Research Fellow and Group Leader Research Interests span epigenetic mechanisms in memory formation, RNA modifications in synaptic plasticity, and therapeutic applications for anxiety disorders. He pioneered discoveries linking dynamic DNA structures (e.g., G-quadruplexes) and RNA methylation to memory stability. Recent Work includes studies on RNA-based therapeutics, stress-induced epigenetic inheritance, and synaptic long noncoding RNA activity. His scientific awards encompass NHMRC and ARC grants for neuroepigenetics research. Key Collaborators: Paul Marshall, Esmi Zajaczkowski Labs: Bredy Laboratory at QBI

Bru Cormand Rifàمشاهده پروفایل

استاد

• Genetics
• Psychiatric Disorders
• Neurogenetics
• +۵ مورد دیگر

Research Focus: His work spans genetics of psychiatric disorders (ADHD, autism, addiction), neurogenetics, and episodic neurological disorders like migraine. Key projects include the CoCA consortium studying ADHD comorbidities and the Aggressotype project investigating aggression mechanisms. Awards: National Habilitation (2011), Advanced Research Accreditation (2011), multiple teaching/research awards. Grants & Projects: Led studies funded by EU (e.g., CoCA, Eat2beNICE) and Spanish Ministry of Science. Major contributions include identifying genes like NFAT5 in cocaine dependence and RBFOX1 in aggression. Collaborations: Member of IMpACT, Psychiatric Genomics Consortium, and CIBER-ER network. Active in international initiatives like the ADHD Working Group of the Psychiatric Genomics Consortium. Publications: Over 100 peer-reviewed articles, including landmark studies on autism genetics and ADHD genome-wide loci. Labs/Teams: Leads the Human Molecular Genetics Research Group, focusing on translational research in psychiatric and neurological disorders.

Andrew Jacksonمشاهده پروفایل

استاد

• Microcephaly
• Cancer
• Autoinflammation
• +۵ مورد دیگر

Professor Andrew Jackson FRS is a Programme Leader at the MRC Human Genetics Unit within the Institute of Genetics and Cancer at the University of Edinburgh. He serves as Group Leader for the Microcephaly, Cancer and Autoinflammation research program and holds an honorary consultant position in Clinical Genetics. Elected as a Fellow of the Royal Society in 2020, he has also been recognized as a Fellow of the Royal Society of Edinburgh and Academy of Medical Sciences (2014) and Member of EMBO (2013). His research program focuses on identifying genes causing inherited disorders of the brain, with particular emphasis on microcephaly, Aicardi-Goutieres syndrome, and connections between genome stability, inflammation, and cancer. The Jackson lab has discovered over 20 human disease genes involved in fundamental cellular processes related to growth and inflammation. His work bridges clinical genetics with basic molecular mechanisms, exploring how faults in nucleases mimic viral infection of the brain and how ribonucleotides in DNA can cause genome damage relevant to cancer. Analysis of his recent publications reveals a strong focus on genome instability mechanisms, with particular attention to how these processes relate to both rare genetic disorders and common diseases. His work integrates human genetics with cellular and molecular approaches, often using model organisms to understand disease mechanisms. Fellow of the Royal Society (2020) Fellow of the Royal Society of Edinburgh (2014) Fellow of the Academy of Medical Sciences (2014) Member of EMBO (2013) Professor Jackson leads an active research group with multiple postdoctoral researchers, technicians, and PhD students. His work is supported by major funders including the Medical Research Council, European Research Council, and EMBO. His research has significant translational potential, particularly in understanding the genetic basis of developmental disorders and identifying mechanisms relevant to cancer therapies. The Jackson lab maintains strong collaborations across the University of Edinburgh and with international partners in the US and Europe, focusing on genomic instability, DNA repair mechanisms, and developmental disorders.

Andrew P. Wojtovichمشاهده پروفایل

دانشیار

• Mitochondrial Physiology
• Reactive Oxygen Species (ROS) Signaling
• Optogenetics
• +۵ مورد دیگر

Andrew P. Wojtovich, Ph.D., is an Associate Professor at the University of Rochester School of Medicine and Dentistry, with joint appointments in the Department of Anesthesiology and Perioperative Medicine and Department of Pharmacology and Physiology . His research focuses on mitochondrial physiology , redox signaling , and optogenetic control of bioenergetics in C. elegans and mammalian models. He received his Ph.D. in Pharmacology (2010) and M.S. in Pharmacology (2007) from the University of Rochester, preceded by dual B.A. and M.A. in Biochemistry and Molecular Biology from Boston University (2005). His lab is affiliated with the Mitochondrial Research and Innovation Group , Neuroscience Graduate Program , and Cellular and Molecular Pharmacology and Physiology Graduate Program . Key research areas include ROS microdomains in neuronal ischemia Protonmotive force regulation of aging Mitochondrial dysfunction in Alzheimer's disease His work is supported by NIH grants R01 NS092558 , R01 NS115906 , R56AG082916 , and R21AG085324-01 . Scientific accolades include 2023 Hypothesis Prize (3rd place) 2021 Student Supervisor of the Year Multiple University Research Awards (2015-2018) Young Investigator Awards (2007, 2012) His lab employs optogenetic tools to control mitochondrial function with precision, leading to groundbreaking insights in stroke outcomes and longevity pathways .

Renu Kowluruمشاهده پروفایل

استاد

• Diabetic Retinopathy
• Mitochondrial Dysfunction
• Epigenetics
• +۳ مورد دیگر

Renu Kowluru is a Professor and Director of Translational Research at the Department of Ophthalmology and Visual & Anatomical Sciences , Wayne State University. Her research focuses on the role of mitochondrial dysfunction and epigenetic modifications in the pathogenesis of diabetic retinopathy , including the phenomenon of metabolic memory where retinal damage persists even after glycemic control. Dr. Kowluru’s work has been recognized by her induction into Wayne State University’s Academy of Scholars (2011), designation as a World Expert by Expertscape (2021), and inclusion in Research.com’s list of the World’s Best Scientists (2025). She has served on high-impact committees such as the National Eye Institute’s Strategic Planning Committee (2020) and the National Eye Advisory Council (2020–2024). Her research has identified mitochondrial DNA damage as a critical driver of oxidative stress in diabetic retinopathy and pioneered the study of mitochondrial epigenetics in this context. She has secured continuous NIH funding (R01 EY014370, EY017313, EY022230, EY033516). The trends in her recent publications highlight long noncoding RNAs , ferroptosis , and mitochondrial DNA repair as central themes. Scientific Awards Wayne State University Academy of Scholars (2011) Expertscape World Expert in Diabetes Complications (2021) Research.com World’s Best Scientists (2025) Dr. Kowluru’s grants and committee roles reflect her leadership in advancing diabetic retinopathy research , including contributions to the Foundation for Vision Research and the Mary Tyler Moore Vision Collaborative Community. Her collaborations span institutions like the Juvenile Diabetes Research Foundation and the American Diabetes Association.

Carlos Guerrero Bosagnaمشاهده پروفایل

مدرس ارشد

• Epigenetics
• Evolutionary Biology
• Environmental Toxicology
• +۴ مورد دیگر

Carlos Guerrero Bosagna is a Senior Lecturer at Uppsala University's Department of Organismal Biology; Physiology and Environmental Toxicology. His research bridges evolutionary biology, epigenetics, and environmental science, focusing on how environmental exposures (e.g., toxins, stress) induce epigenetic modifications that influence developmental processes and transgenerational phenotypic variation. Role: Senior Lecturer, Uppsala University Department: Physiology and Environmental Toxicology Key Projects: Epigenetic stress response in chickens, metabolic/reproductive effects of environmental toxins, germline epigenetic variation in speciation His work has secured a FORMAS grant for modeling environmental toxicant impacts on chicken reproduction and metabolism. Recent publications analyze avian methylation patterns , mito-nuclear interactions , and Z-chromosome epigenetic regulation . Collaborations span poultry science, computational biology, and global environmental epigenetics research. Scientific awards include a FORMAS grant for environmental toxicology research His research emphasizes sustainability and evolutionary innovation, with lab projects tracking epigenetic changes across six generations to mimic early speciation events. Methodological contributions include protocols like GBS-MeDIP for concurrent genetic/epigenetic analysis.

Catherine Greenمشاهده پروفایل

دانشیار

• Chromosome Dynamics
• DNA Replication
• Genomic Instability
• +۳ مورد دیگر

Professor Catherine Green is an Associate Professor at the University of Oxford, jointly appointed at the Wellcome Trust Centre for Human Genetics within the Nuffield Department of Medicine and also affiliated with the Department of Zoology at the University of Cambridge. She leads the Chromosome Dynamics Group , focusing on fundamental questions surrounding DNA replication and genome stability in mammalian cells. Her research investigates the intricate choreography of proteins at replication forks, particularly the multifaceted roles of the sliding-clamp protein PCNA. By mapping the full complement of PCNA interactors and dissecting how these interactions shift under replication stress, her team seeks to uncover how genomic instability and cancer-driving alterations arise. Additional projects explore the three-dimensional architecture of replication foci, the transmission of epigenetic marks during DNA synthesis, and the identification of substrates for protein methyltransferases that fine-tune chromatin states. The recent publication record underscores her dual commitment to basic chromosome biology and translational medicine: from mechanistic studies on aluminium-induced genomic instability (2020) to high-impact clinical trials of the ChAdOx1 nCoV-19 (AZD1222) vaccine across multiple continents (2020–2021). These articles collectively highlight her expertise in molecular medicine, cancer genomics, immunology, and large-scale clinical vaccinology. Contact & Affiliations: Email: cmg1003@well.ox.ac.uk Web: NDM Profile Address: Henry Wellcome Building of Genomic Medicine, University of Oxford