جست‌وجوی استاد و پژوهشگر

Karen Kemper Hirschiمشاهده پروفایل

استاد

• Cell Biology
• Developmental Biology
• Vascular Biology
• +۵ مورد دیگر

Karen Kemper Hirschi is a Professor of Cell Biology at the University of Virginia School of Medicine . Her research focuses on the cellular and molecular mechanisms underlying blood vessel formation , with particular interest in vascular development, stem/progenitor cell regulation, and intercellular signaling pathways. BS in Nutritional Biochemistry, Penn State University PhD in Nutritional Biochemistry, University of Arizona Postdoctoral Fellow in Cell Biology and Vascular Biology, University of Arizona and Harvard Medical School Her laboratory investigates how vascular cells acquire specialized functions, emphasizing signaling pathways that modulate endothelial cell cycle progression , arterial-venous specification , and stem cell niche interactions . Key areas include connexin-mediated signaling , hemogenic endothelium , and vascular contributions to disease states like obesity and heart failure. Recent work by Dr. Hirschi’s lab reveals connections between clonal hematopoiesis and cardiovascular disease, metabolic dysregulation in vascular cells, and the role of gap junctions in neurovascular interactions. Collaborators span disciplines including computational biology, regenerative medicine, and immunology. She leads a research team with online presence , supported by grants and publications in top-tier journals like Nature , Science , and Circulation . Her work bridges fundamental vascular biology to translational applications in organoid culture , endothelial cell specification , and cardiovascular disease modeling .

• Immunology
• Hematology
• Medical Genetics
• +۵ مورد دیگر

Dr. Naomi McGovern is a researcher affiliated with Newcastle University , focusing on immunology, hematology, and medical genetics. Her work explores dendritic cell biology, GATA2 mutations, and primary immunodeficiency disorders. Key research areas: Dendritic cell subsets, antigen presentation, and genetic immune dysfunction Collaborators: Professors Matthew Collin, Muzlifah Haniffa, and Venetia Bigley Her publications (selected) span 2011–2017, with recent work on fetal dendritic cells, BRAF mutations in histiocytoses, and three-dimensional mapping of dermal immune networks. She investigates how GATA2 and STAT2 deficiencies alter immune development and viral susceptibility. Notable contributions include identifying cross-presenting dendritic cells in human skin and establishing connections between murine CD103+ and human CD141+ cells. Her research informs stem cell transplant strategies for DCML deficiency and vaccine design targeting dendritic cell subsets.

Tim Gardnerمشاهده پروفایل

دانشیار

• Neuroengineering
• Neural Circuit Dynamics
• Machine Learning
• +۷ مورد دیگر

Tim Gardner is an Associate Professor of Neuroengineering and holds the Robert & Leona DeArmond Chair at the University of Oregon's Knight Campus. He leads the Gardner Lab, focusing on neural circuit dynamics in songbirds and developing neural interfaces. His research integrates machine learning, electrophysiology, and advanced imaging to study vocal behavior and motor learning. Prior to academia, he contributed to Neuralink Corp's brain-machine interface development. Gardner earned a B.S. in Physics from Princeton University, a Ph.D. in Biology and Physics from Rockefeller University, and completed postdoctoral work at Rockefeller and MIT. Education: Bachelor’s in Physics, Princeton University Ph.D. in Biology and Physics, Rockefeller University Postdoctoral Fellowships: Rockefeller University and MIT Research interests span neuroengineering, vocal learning in songbirds, deep learning applications, and bioelectronic medicine. The lab pioneers techniques like direct laser writing for 3D electrodes and applies reinforcement learning to understand neural self-organization. Recent work includes TweetyBERT for automated birdsong analysis and neural interface materials like amorphous silicon carbide. Awards: Robert & Leona DeArmond Chair in Neuroengineering Advising & Grants: Supervises graduate students and postdocs in neuroengineering and bioengineering. Projects include nerve regeneration studies, microscale printing, and neural interface design. Collaborates with industry (e.g., Neuralink) and startups like Mattrix Technologies. Labs/Teams: The Gardner Lab is part of the Knight Campus, emphasizing interdisciplinary research. Current projects involve 3D printing for biomedical devices and bidirectional brain interfaces. Undergraduates and graduate students contribute to projects like nerve cuff development and computational modeling of vocal sequences.

Ute Kochمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Developmental Biology
• Cellular and Molecular Immunology
• +۵ مورد دیگر

Ute Koch is a Researcher at the École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the School of Life Sciences (SV) and the Institute of Bioengineering (ISREC). She is part of the UPRAD group under Prof. Radtke, focusing on Notch signaling pathways in immune cell development, hematopoiesis, and cancer. Her work spans molecular biology, developmental biology, and immunology, with a particular emphasis on T cell maturation, B cell regulation, and the role of stromal niches in immune responses. Education and Positions: Koch’s academic trajectory includes roles such as Research and Teaching Associate at EPFL, contributing to both research and teaching in life sciences. She has supervised PhD students including Mateusz Antoszewski and Delphine Tardivon, whose theses addressed Notch-driven leukemia and chronic lymphocytic leukemia mechanisms. Research Interests: Her expertise encompasses the interplay between Notch signaling and immune cell fate decisions, including T-cell acute lymphoblastic leukemia (T-ALL), B-cell maturation, and the role of fibroblastic niches in orchestrating immune responses. She investigates Notch’s role in stem cell maintenance, tumor progression, and graft-versus-host disease. Publications Overview: Koch’s research has been published in high-impact journals like the Journal of Experimental Medicine, Immunity, and Nature Communications. Recent work highlights Notch’s role in T-cell differentiation, B-cell positioning in the spleen, and leukemia pathogenesis. Her studies often integrate experimental models (e.g., murine systems) with molecular and cellular biology approaches. Awards and Grants: While no specific awards are listed, her extensive publication record and collaborative projects indicate recognition within the field. Her work has been supported by grants related to immunology, stem cell biology, and cancer research. Labs and Collaborations: She contributes to the Radtke Lab, focusing on Notch signaling’s multifaceted roles in health and disease. Her interdisciplinary approach bridges basic research with clinical implications in oncology and immune disorders.

Jean-Luc Boullandمشاهده پروفایل

دانشیار

• Spinal Cord Injury
• Locomotion
• Neural Plasticity
• +۴ مورد دیگر

Jean-Luc Boulland is an Associate Professor at the University of Oslo's Institute of Basic Medical Sciences (Division of Physiology). His research focuses on spinal cord injury recovery mechanisms, functional electrical stimulation, and translational medical technologies. He leads projects on spinal trauma models in large animals and has affiliations with the NERD (NEurotrauma, Repair and Development) research group. His work integrates biomechanical injury models, sensor technologies, and stem cell tracking methods. Key contributions include developing MEMS-based pressure sensors and multimodal spinal injury apparatuses. Articles highlight innovations in sensor systems, locomotor circuitry repair, and cell-based therapies. Boulland's collaborations span neurobiology, biomedical engineering, and regenerative medicine. His lab explores tissue regeneration pathways and clinical validation of novel treatments, aiming to bridge basic science with clinical applications.

Jim Wellsمشاهده پروفایل

استاد

• Protein Engineering
• Drug Discovery
• Cell Surface Proteomics
• +۴ مورد دیگر

Jim Wells is a Professor at the University of California San Francisco (UCSF), affiliated with the Departments of Pharmaceutical Chemistry and Cellular & Molecular Pharmacology. He founded the Small Molecule Discovery Center and served as Chair of Pharmaceutical Chemistry. His research focuses on cell surface proteomics, protein engineering, and targeted drug discovery. Education: BA in Biochemistry and Psychology from UC Berkeley (1973), PhD in Biochemistry from Washington State University (1979), and postdoctoral training at Stanford University. Wells’ research spans enzyme engineering, apoptosis, and drug development for cancer and neurodegenerative diseases. His lab employs mass spectrometry and affinity-directed technologies to map cell surface changes in disease states. Recent work includes CRISPRi screens for autism risk genes, hypoxia-induced proteomic remodeling in pancreatic cancer, and engineered proteins for genome editing. His publications highlight expertise in protein engineering, chemical biology, and cancer signaling. Awards include election to the National Academy of Sciences and the Chan Zuckerberg Biohub Investigator designation. Wells has secured significant NIH funding for projects related to proteolysis, signaling, and biomarker discovery. Scientific Awards: Damon M. Runyon Fellowship, Pfizer Award, Christian B. Anfinsen Award, and others. He has co-founded multiple biotech companies, including Genentech (1982), Sunesis Pharmaceuticals (1998), and EpiBiologics (recently), advancing therapeutic proteases, RAF inhibitors, and extracellular degraders.

• Bioimaging
• Advanced Microscopy
• Image Processing
• +۲ مورد دیگر

Dr. Pablo Loza-Alvarez leads research in bioimaging and advanced microscopy techniques at ICFO, focusing on interdisciplinary applications in photonics and biology. The group develops cutting-edge methodologies including beam engineering, wavefront control, and novel contrast agents for biomedical samples. Research integrates multiphoton/confocal microscopy, light-sheet fluorescence microscopy, and computational algorithms for image quantification. Current EU-funded projects include PROMPT (neurobiology of treatment response) and Psych-STRATA (early detection of treatment resistance). Recent publications demonstrate strong trends in neuro-immunology, retinal imaging, and nanotechnology interfaces, with significant cross-disciplinary applications in plant pathology and chemometrics. Collaborative networks span Aston University, CRG Barcelona, and multiple European institutions.

Emily Sylwestrakمشاهده پروفایل

استادیار

• Neuroscience
• Molecular Biology
• Cellular Neuroscience
• +۴ مورد دیگر

Emily Sylwestrak is an Assistant Professor in the Department of Biology at the University of Oregon , affiliated with the College of Arts and Sciences . Her research focuses on understanding molecular, cellular, and circuit mechanisms underlying motivated behavior, particularly in the habenula's role in reward processing and neuropsychiatric disorders like addiction and depression. The Sylwestrak Lab employs cell-type specific activity monitoring and behavioral analysis to dissect how neuronal populations drive behavior. Education details are not explicitly stated in the provided texts, but her work emphasizes advanced techniques like intact-tissue sequencing and hydrogel-based RNA detection. Her lab integrates molecular, genetic, and behavioral approaches to study neural circuits' functional specialization. Research highlights include studies on habenular neurons' reward computations, endocannabinoid signaling in sensory cortex plasticity, and synaptic refinement mechanisms. Her methods bridge molecular biology with systems neuroscience, focusing on circuit-level analysis. Lab philosophy emphasizes interdisciplinary collaboration and translational insights into neuropsychiatric disorders. The lab is affiliated with the University of Oregon's broader neuroscience community, contributing to interdisciplinary research initiatives.

Matthew Fisherمشاهده پروفایل

دانشیار

• Rehabilitation Engineering
• Regenerative Medicine
• Tissue Engineering
• +۴ مورد دیگر

Matthew Fisher is an Associate Professor in the Department of Biomedical Engineering at North Carolina State University (NC State) and an Adjunct Associate Professor in the Department of Orthopaedics at NC State. He is also the Director of Graduate Studies in Biomedical Engineering. Fisher joined NC State in 2014 as part of the Translational Regenerative Medicine cluster hire initiative. His research focuses on applying engineering principles to understand and improve regenerative therapies for musculoskeletal soft tissues, including ligaments, tendons, and menisci. Key areas include bioscaffold design, advanced manufacturing (e.g., 3D printing), and in vivo biomechanical studies using porcine models. Education: Ph.D., Bioengineering, University of Pittsburgh (2010) B.S., Biomedical Engineering, Columbia University (2005) Research Interests: The lab investigates tissue growth mechanics, bioscaffold fabrication, and translational strategies for soft tissue repair. Current projects involve 3D-printed fibrous scaffolds for tendon/ligament regeneration, robotics-based joint biomechanics analysis, and the role of growth factors in tissue healing. Fisher emphasizes bridging nanoscale material design with macroscale functional outcomes. Awards: Rising Star Award (BMES, 2020) NIH Postdoctoral Fellowship (2013) North Carolina State University Seed Award (2015) Teaching: BME 362: Biomaterials Characterization BME 590: Functional Tissue Engineering BME 484/584: Tissue Engineering Fundamentals Labs/Teams: Fisher leads the Regenerative Orthopaedics Lab, collaborating with NC State's Department of Mechanical Engineering and UNC-Chapel Hill. The lab integrates robotics, imaging, and biomaterials to develop preclinical models for translational research.

Martin Griffinمشاهده پروفایل

استاد

• Transglutaminase Biochemistry
• Cellular Signaling Pathways
• Tissue Fibrosis and Repair
• +۵ مورد دیگر

Professor Martin Griffin is a renowned biochemist and molecular biologist at Aston University's School of Biosciences, part of the College of Health and Life Sciences. He has dedicated over three decades to studying transglutaminases, enzymes critical for protein crosslinking in tissues like skin and blood clots. His research focuses on tissue transglutaminase (TG2), exploring its roles in cell death, fibrosis, tumor progression, and cystic fibrosis. He leads the Biosciences Research Group (BRG) and the Aston Research Centre for Health in Ageing, driving innovations in biomaterials for tissue repair. Griffin holds professional roles including President of the European Association for Higher Education in Biotechnology (2004) and Fellow of the Institute of Biology (2005). Qualifications: BSc (1st class honours) in Applied Biology from the University of Salford (1970), PhD in Microbial Biochemistry from Aberystwyth University (1974). Research Interests: Transglutaminase biochemistry, extracellular matrix dynamics, fibrosis mechanisms, biomaterial engineering, and enzyme-based therapies. His work bridges fundamental science and translational medicine, addressing clinical challenges like wound healing and organ regeneration. Recent projects include developing TG2 inhibitors for pulmonary fibrosis and using transglutaminases to engineer biocompatible materials. Article Trends: Over 119 publications highlight his focus on TG2 inhibition's antifibrotic effects, zebrafish transglutaminase models, and mesothelioma cell signaling. Collaborations span oncology, immunology, and biomaterials engineering. Awards: Fellow of the Institute of Biology (2005), European Biotechnology Leadership Role (2004). Professional Activities: Peer review for EPSRC, REF 2014 panel member, and conference participation (e.g., EMBO Cellular Signaling 2012). Labs/Teams: Leads interdisciplinary teams at Aston, integrating bioengineering and cellular biology to advance healthcare solutions.

Ashutosh Khandhaمشاهده پروفایل

استادیار

• Medical Imaging
• Biomedical Instrumentation
• Device Development
• +۳ مورد دیگر

Ashutosh Khandha is an Assistant Professor in the Department of Biomedical Engineering at the University of Delaware. He holds a Ph.D. in Biomedical Engineering from the University of Delaware (2016), an MS in Bioengineering from the University of Toledo (2004), and a BS in Biomedical Engineering from the University of Mumbai (2000). His research focuses on translational engineering education and biomechanical studies, particularly in knee mechanics, ACL reconstruction outcomes, and osteoarthritis development post-injury. Key research interests include analyzing gait mechanics post-ACL surgery, muscle co-contraction dynamics, and the biomechanical implications of surgical interventions like PEEK spacers in spinal fusion. He has contributed to understanding how early postoperative loading asymmetries correlate with long-term cartilage health and osteoarthritis progression. His publications highlight advancements in ACL rehabilitation protocols, gender differences in recovery, and the role of meniscal treatments. While no formal awards are listed, his work bridges clinical practice and biomechanical engineering, emphasizing practical training in education. Dr. Khandha’s research also explores innovative educational approaches, such as integrating bio-inspired design and STEAM methodologies into computer-aided design courses, to enhance student learning outcomes.

Tracy Hookwayمشاهده پروفایل

دانشیار

• Tissue Engineering
• Stem Cell Biology
• Cardiovascular Physiology
• +۲ مورد دیگر

Dr. Tracy Hookway is an Associate Professor in the Department of Biomedical Engineering at Binghamton University's Thomas J. Watson College of Engineering and Applied Science. Her research specializes in developing predictive in vitro models of human cardiovascular tissues using multi-scale 3D cultures of stem cells. Key research areas include tissue development, homeostasis, pathophysiological states, and bi-directional cell-environment interactions. Research interests focus on: Stem cell-driven tissue morphogenesis Cardiovascular tissue engineering Age-specific tissue changes Bioprocessing optimization Cell-extracellular matrix dynamics Publication analysis reveals consistent focus on cardiac tissue engineering (73% of recent articles), stem cell differentiation (60%), and advanced imaging/bioprinting techniques (47%). Awards include the American Heart Association Postdoctoral Fellowship and multiple innovation awards from Worcester Polytechnic Institute.

Linna Zhouمشاهده پروفایل

پژوهشگر

• Bioengineering
• Cancer Research
• Tissue Engineering
• +۲ مورد دیگر

Dr. Linna Zhou is a Researcher in the Department of Chemistry at the University of Oxford, affiliated with the Ludwig Institute for Cancer Research and Professor Hagan Bayley's group. She received the CRUK Oxford Centre Development Fund for her work on nervous system involvement in gastrointestinal cancer progression. Her research integrates bioengineering, neuroscience, and oncology to develop engineered tissue models. She investigates neural-immune-tumor interactions using advanced 3D bioprinting techniques and microfabrication technologies. Publications spanning 2006-2025 demonstrate her interdisciplinary approach, with recent emphasis on 3D-printed tissue models for cancer research, neural-tissue interfaces, and metabolic regulation in disease. Her work consistently bridges engineering precision with biological complexity.

Shadab Abadpourمشاهده پروفایل

پژوهشگر ارشد

• Stem Cell Biology
• Regenerative Medicine
• Diabetes Research
• +۳ مورد دیگر

Shadab Abadpour is a Postdoctoral Research Fellow at the University of Oslo, affiliated with the Institute for Molecular Biosciences (IMB) and the Hybrid Technology Hub . He is part of The Scholz Group , focusing on advancing bioengineering and regenerative medicine approaches for pancreatic islet research and diabetes treatment. His work integrates stem cell biology, organ-on-a-chip technologies, and proteomics to study islet function, transplantation outcomes, and metabolic interactions. Research interests include stem cell differentiation , bioengineered transplantation platforms , and metabolic crosstalk modeling . He collaborates extensively with teams in molecular biology, analytical chemistry, and clinical research, contributing to projects like improving islet preservation in 3D bioprinted scaffolds and developing organ-on-a-chip systems for disease modeling. Abadpour has published widely in journals such as Frontiers in Bioengineering and Biotechnology , Advanced Healthcare Materials , and Diabetologia . His recent studies explore age-dependent islet dynamics, glucose regulation in stem cell differentiation, and proteomic markers of islet homeostasis. He also investigates the role of prostaglandin signaling and adipose-derived stromal cells in enhancing islet survival post-transplantation. Key contributions include the development of a pump-less organ-on-chip platform to model islet-liver interactions and the use of LC-MS techniques for analyzing insulin secretion from stem cell-derived islet organoids. His work bridges fundamental research and translational applications in diabetes therapy.

• Proteomics
• Metabolomics
• Gene Expression Analysis
• +۳ مورد دیگر

David Rocke is a Professor at the University of California, Davis , affiliated with the Department of Public Health Sciences . His research focuses on proteomics , metabolomics , gene expression analysis , and statistical bioinformatics , with applications in molecular biology and radiation biology . Email: dmrocke@ucdavis.edu Research Interests: His work addresses statistical methods for analyzing high-throughput biological data, particularly in proteomics and metabolomics, with applications to disease mechanisms (e.g., diabetic foot ulcers, FOP), forensic identification, and radiation response. Recent studies emphasize comparative efficacy of regenerative therapies and environmental toxicology. Notable Contributions: Developed computational models for proteomic data in human identification and disease diagnostics Investigated radiation biology applications in wound healing and stress response