جست‌وجوی استاد و پژوهشگر

Clifford P. Brangwynneمشاهده پروفایل

استاد

• Biophysics
• Bioengineering
• Soft Matter Physics
• +۳ مورد دیگر

Clifford P. Brangwynne is the June K. Wu '92 Professor of Chemical and Biological Engineering and Bioengineering at Princeton University, serving as Director of the Omenn-Darling Bioengineering Institute. His research bridges biophysics, bioengineering, and cell biology to investigate the physical principles governing intracellular organization through liquid-liquid phase separation. Education Ph.D. in Applied Physics, Harvard University (2007) B.S. in Materials Science and Engineering (minor in Physics), Carnegie Mellon University (2001) Research Focus Brangwynne's lab pioneers the study of membrane-less organelles (biomolecular condensates) formed via phase separation, exploring their roles in nuclear architecture, genome regulation, and disease mechanisms. His work integrates soft matter physics with advanced cell biology to uncover how these condensates form, function, and contribute to pathological protein aggregation in neurodegenerative disorders, while developing synthetic organelle engineering for biomedical applications. Publication Trends His publications consistently demonstrate how liquid phase condensation governs cellular organization across scales—from nuclear genome restructuring to pathological aggregation. The interdisciplinary approach reveals fundamental physical principles while driving technological innovations in organelle engineering and disease modeling. Major Awards Breakthrough Prize for Life Sciences (2023) Raymond and Beverly Sackler International Prize in Biophysics (2023) Tsuneko & Reiji Okazaki Award (2021) Wiley Prize in Biomedical Sciences (2020) Blavatnik National Award in Life Sciences (2020) Human Frontier Science Program Nakasone Award (2020) Michael and Kate Bárány Award, Biophysical Society (2020) HHMI Transformative Technology Award (2019) MacArthur Fellow (2018) HHMI, Simons Foundation, and Bill & Melinda Gates Foundation Faculty Scholar (2016) SCB Gibco Emerging Leader Prize, American Society of Cell Biology (2015) Sloan Research Fellowship (2014) NSF CAREER Award (2013) NIH New Innovator Award (2012) Searle Scholar Award (2012) Helen Hay Whitney Fellow (2008-2010) Advising and Funding He mentors graduate students including Jordy Botello, Yi-Che (Eje) Chang, Yoonji Kim, Claire Weaver, Lennard Wiesner, and Jessica Zhao. Research is supported by HHMI, Simons Foundation, Bill & Melinda Gates Foundation, NIH, NSF, and the Human Frontier Science Program. Laboratory and Collaborations Leading the Soft Living Matter Group, Brangwynne collaborates with theorists including Mikko Haataja (Princeton Mechanical Engineering), Ned Wingreen (Princeton Molecular Biology), and Rohit Pappu (WUSTL), while contributing to the NIH 4D Nucleome Consortium to advance understanding of nuclear organization.

Suliana Manleyمشاهده پروفایل

استاد

• Super-resolution Microscopy
• Single-molecule Biophysics
• Protein Assembly
• +۵ مورد دیگر

Suliana Manley is a Full Professor at the École Polytechnique Fédérale de Lausanne (EPFL) , affiliated with the School of Basic Sciences and the Laboratory of Experimental Biophysics . She also holds teaching and research roles in EPFL's School of Life Sciences and Swiss Plasma Center , focusing on interdisciplinary biophysical studies. Education : PhD in Physics (2004), Harvard University Bachelor's in Physics & Mathematics (1997), Rice University Manley's research centers on super-resolution fluorescence imaging , single-molecule tracking , and quantitative biophysics . Key themes include: Understanding protein assembly dynamics at cellular membranes Elucidating viral assembly mechanisms (e.g., HIV-Gag) Developing 3D imaging algorithms and high-density data reconstruction tools like PALMsiever and FALCON Quantifying nanoscale organization in systems like telomeres and centrioles Her work bridges optical physics , computational image analysis , and cellular biology , with notable Nature and PNAS publications. Collaborations span bioengineering , genetics , and medical research . Scientific Awards : Featured in Nature Methods Research Highlights (3x) Very Important Paper and Cover Article (ChemBioChem, 2012) Postdoctoral Fellow, NIH and MIT Advising & Collaborations : Current PhD students in biophysics, cellular biology, and bioengineering Former students: Anna Archetti, Aleksandr Benke, Andrea Callegari, and others Co-founder of tools for high-density super-resolution microscopy and live-cell imaging Labs & Teams : Leads the Laboratory of Experimental Biophysics at EPFL, integrating physics-based methods into biological questions. The lab focuses on quantitative imaging , computational modeling , and software development for nanoscale analysis.

Sudin Bhattacharyaمشاهده پروفایل

دانشیار

• Systems Toxicology
• Computational Biology
• Gene Expression Analysis
• +۳ مورد دیگر

Sudin Bhattacharya is an Associate Professor at the BioMolecular Science Gateway, Michigan State University, with affiliations in the Genetics & Genome Sciences Program and Cell & Molecular Biology Program. His research bridges computational biology and toxicology to understand complex biological systems. Email: sbhattac@msu.edu Research Interests Dr. Bhattacharya specializes in systems toxicology, focusing on computational modeling of gene regulatory networks, single-cell transcriptomics, and molecular dynamics in response to environmental toxicants. His work examines how chemical exposures disrupt cellular pathways and contribute to disease mechanisms. Article Trends His recent publications emphasize: Single-cell and single-nucleus RNA sequencing for toxicological profiling Computational models of circadian rhythms and intercellular communication Dose-dependent responses to environmental chemicals like TCDD and heavy metals Mechanistic studies of adipose tissue remodeling and hypertension Applications of machine learning in chemical risk assessment Integrative approaches to liver metabolism and disease modeling Scientific Contributions Dr. Bhattacharya has pioneered multiscale modeling of biological systems, particularly in hepatic and vascular contexts. His work on the aryl hydrocarbon receptor and PPARα signaling networks has advanced predictive toxicology frameworks.

Soeren Lienkampمشاهده پروفایل

استادیار

• Molecular Biology
• Genetics
• Developmental Biology
• +۵ مورد دیگر

Prof. Dr. Soeren Lienkamp is an Assistant Professor at the Institute of Anatomy , Faculty of Medicine , University of Zurich . His work bridges digital education and genetic research , focusing on enhancing medical teaching through innovative formats. Research Interests : Genetics, developmental biology, kidney disease modeling, CRISPR applications, digital medical education, and advanced microscopy. Methodologies : Combines Xenopus tropicalis models, deep learning , and bioengineering to study genetic kidney disorders and improve diagnostic tools. Publication Trends : His recent articles highlight predictable genome editing , 3D imaging technologies , and mechanistic insights into kidney and eye development. Earlier works focus on ciliary function , Wnt signaling , and metabolic stress in renal cells.

Prashant Maliمشاهده پروفایل

استاد

• Genome Engineering
• RNA Editing
• Stem Cell Research
• +۴ مورد دیگر

Prashant Mali is a Professor in the Department of Bioengineering at the University of California, San Diego . His research bridges genome engineering, RNA biology, and biomedical applications, with a focus on CRISPR-Cas systems and ADAR-mediated RNA editing. Education : Ph.D. in Bioengineering Key Affiliations : UC San Diego, Altman Clinical and Translational Research Institute Dr. Mali's work centers on CRISPR-Cas9 technology , RNA editing , and human pluripotent stem cells . His lab develops tools for programmable gene regulation, synthetic lethal screens, and metabolic pathway analysis in disease contexts. Recent publications highlight innovations in circular RNA engineering , ADAR activity mapping , and metabolic reprogramming in cancer . His team employs multi-omics approaches and in vivo models to translate genome editing into clinical applications. Students and Collaborators Current Lab Members : Sami Nourreddine (Postdoc), Amir Dailamy (Graduate), Andrew Portell (Graduate), Michael Tong (Graduate) Alumni : Kyle Ford (PhD 2022), Nathan Palmer (PhD 2022), Udit Parekh (PhD 2021) Research Themes CRISPR Screens : Synthetic lethal interactions, oncogenic pathways, metabolic vulnerabilities RNA Editing : ADAR engineering, circular guide RNAs, clinical translation Tissue Engineering : Vascularized organoids, cardiac maturation, ex vivo models

• Plant Developmental Biology
• Epigenetics
• Plant Genetics
• +۵ مورد دیگر

Ueli Grossniklaus is an Ordinary Professor at the University of Zurich within the Faculty of Mathematical and Natural Sciences , affiliated with the Department of Plant and Microbiology . His work focuses on plant developmental biology, particularly epigenetic and genetic mechanisms governing reproduction and adaptation. Key Courses: Epigenetics, Plant Biology Workshop, Group Seminars on Current Research Laboratory Techniques: Advanced methods in plant cell mechanics, transcriptomics, and genome editing Research Interests span plant epigenetics, reproductive biology, and the interplay between environmental stress and genetic regulation. He investigates: Mechanistic control of gametogenesis and fertilization Epigenetic contributions to plant adaptation Evolutionary implications of asexual reproduction Biophysical forces in plant cell growth Publication Trends (2025–2018) reveal expertise in: Arabidopsis and fern model systems Epigenetic regulation (DNA methylation, histone dynamics) Apomixis and hybrid seed failure mechanisms Biomechanics of pollen tubes and carnivorous plants Genome editing tools (CRISPR) and long-read sequencing Scientific Collaborations include interdisciplinary projects on: Microfluidic devices for plant cell analysis Gene drive ecology and ethics 3D imaging of plant reproductive structures Advising and Grants focus on mentoring through research internships in developmental biology, genetics, and systems biology. His lab engages in: Epigenetic response to environmental stress Cell wall mechanics in reproduction Computational modeling of plant growth Laboratory Teams integrate plant biologists, bioengineers, and computational scientists to study: Mechanistic gene regulation Evolutionary developmental biology Microrobotics for cellular force measurement

Charu Gupta Kumarمشاهده پروفایل

استاد پژوهشی

• Systems and Computational Biology
• Microbiome/Pathogen Computational Genomics
• Metabolic Network Modeling
• +۳ مورد دیگر

Charu Gupta Kumar is a Research Professor in the Department of Bioengineering at the University of Illinois Urbana-Champaign, affiliated with the Neuroscience program. Her research focuses on systems and computational biology, integrating computational genomics, bioinformatics, and systems biology approaches to study microbiome/pathogen dynamics, neurological diseases, and evolutionary processes. She leads the Systems and Computational Biology Group, emphasizing interdisciplinary methodologies to address complex biological questions. Her academic roles include a zero-time appointment in the Department of Neuroscience (2013–present) and service as an admission reviewer for the Carle Illinois College of Medicine (2020–2022). She advises a diverse cohort of undergraduate and graduate students engaged in bioengineering and computational biology projects. Her work bridges environmental microbiology with human health, exploring astrocyte roles in neurological disorders like glioblastoma and autism, and investigating evolutionary mechanisms of metabolic networks across species. Publications highlight contributions to bovine genomics, microbial community analysis in subsurface environments, and computational tools for genomic data management. Her research trends emphasize translational applications of computational biology to environmental and clinical challenges, with recent focus on microbiome-disease interactions and astrocyte signaling pathways. Advising spans mentoring over 18 students across bioengineering and computer science disciplines, with notable alumni advancing to institutions like MIT and Johns Hopkins. She collaborates with跨学科 teams in bioengineering and neuroscience, contributing to the broader Grainger College of Engineering research ecosystem.

Michael Harrisonمشاهده پروفایل

استادیار

• Vascular Biology
• Regenerative Medicine
• Developmental Biology
• +۱۱ مورد دیگر

Michael Harrison is an Assistant Professor in the Department of Cell and Developmental Biology at Weill Cornell Medicine, where he leads the Regeneration and Development Lab within the Graduate School of Medical Sciences. His research focuses on vascular development and regeneration using zebrafish as a model organism, with emphasis on coronary and cerebral vasculature. Education: B.Sc. in Genetics, University of Edinburgh (2005) Ph.D. in Developmental Genetics, University of Sheffield (mentor: Vincent Cunliffe) Postdoctoral Fellowship, Saban Research Institute, Children’s Hospital Los Angeles (CIRM Fellow) Harrison's research centers on understanding how blood and lymphatic vessels form and regenerate, particularly in the heart and brain. His lab investigates coronary vessel development, the role of lymphatic systems in inflammation and regeneration, and revascularization after injury. By leveraging zebrafish genetics and advanced imaging, his work aims to uncover pathways that could be harnessed for regenerative therapies in humans. His recent publications reveal key signaling mechanisms such as Cxcr4-Cxcl12 in coronary development and the two-step formation of cardiac lymphatics. The 15 most recent articles demonstrate a strong, consistent research trajectory in vascular biology and regeneration, with increasing use of advanced techniques like single-nuclei multiomics, fluidic imaging devices, and CRISPR-based genome editing. His work spans developmental mechanisms, functional imaging, and translational applications in cardiac repair. Scientific Awards: No awards explicitly mentioned in the provided text. Harrison actively mentors a team of postdoctoral fellows, research assistants, and students, several of whom have progressed to medical school or research careers. His lab collaborates extensively, particularly with Ching-Ling Lien's group. He has secured research space and funding to support ongoing projects in cardiac and cerebral vasculature. The lab is actively recruiting rotation students from BCMB, PBSB, IMP, and Tri-Institutional programs, as well as postdoctoral researchers and research assistants, indicating an expanding research team and active grant support. Labs and Teams: Regeneration and Development Lab, Weill Cornell Medicine Collaborations with Ching-Ling Lien Lab Member of Tri-Institutional PhD Programs Active participation in BCMB, PBSB, and IMP training programs

Ben Raphaelمشاهده پروفایل

استاد

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۶ مورد دیگر

Ben Raphael is a Professor in the Department of Computer Science at Princeton University, with affiliations at the Lewis-Sigler Institute for Integrative Genomics, Omenn-Darling Bioengineering Institute, and Center for Statistics and Machine Learning. He is also an Affiliate Faculty member at the Rutgers Cancer Institute of New Jersey, Irving Institute for Cancer Dynamics at Columbia University, and New York Genome Center. His research focuses on computational methods for analyzing large-scale biological data, emphasizing cancer evolution, network/pathway analysis, and structural variation in genomes. Research Trends: His recent work spans cancer lineage trees, spatial transcriptomics, optimal transport for developmental models, and network analysis of mutations. Articles highlight applications in prostate cancer, pancreatic cancer, and single-cell genomics. Scientific Awards: 2024 ACM Fellow 2023 RECOMB Test of Time Award 2022 RECOMB Test of Time Runner-Up 2021 ISCB Innovator Award 2021 RECOMB Best Paper Runner-Up 2020 ISCB Fellow 2020 AACR Team Science Award 2011 NSF CAREER Award 2013 RECOMB Best Paper 2010-2012 Sloan Research Fellowship Advising: He has mentored numerous Ph.D. students and postdoctoral fellows, many of whom have transitioned to academic and industry roles. Current advisees include Uthsav Chitra, Gillian Chu, and Alexander Strzalkowski. Labs & Teams: Raphael leads the Raphael Lab at Princeton, developing tools like HotNet2, CHISEL, and HATCHet for cancer genomics and network analysis.

• Biomechanics/Bioengineering
• Biomedical Sciences
• Muscle Cells
• +۷ مورد دیگر

Woojin Han is an Assistant Professor in the Departments of Orthopedics and Cell, Developmental & Regenerative Biology at the Icahn School of Medicine at Mount Sinai. His research program focuses on the mechanobiology of skeletal muscle stem and progenitor cells, with applications in disease modeling and the development of advanced therapeutics for muscle injuries and degenerative diseases. Dr. Han earned his BS in Biomedical Engineering from the University of Rochester and his MS and PhD in Bioengineering from the University of Pennsylvania. He completed his postdoctoral training at the Georgia Institute of Technology, where he received awards from the American Federation for Aging Research (AFAR) and the NIH. Dr. Han's research integrates biomaterials, bioengineering, and in vivo genetic approaches to investigate cell-matrix interactions and mechanobiological signaling, aiming to uncover the mechanisms driving muscle regeneration and pathology. His work is supported by the National Institutes of Health (NIH) and the Department of Defense (DoD). Analysis of Dr. Han's recent publications reveals a strong focus on muscle regeneration mechanisms, particularly examining the role of extracellular matrix proteins, mechanical confinement, and signaling pathways in muscle stem cell behavior. His research spans from fundamental mechanobiology to translational applications using biomaterials for tissue regeneration. 2025 NEBEC Emerging Investigator Award 2024 Mount Sinai Faculty Council Award for Junior Faculty 2023 Popular Science's The Brilliant 10 2022 Stephen I. Katz Early Stage Investigator Grant Awardee American Federation for Aging Research (AFAR) award NIH award Dr. Han's research is supported by significant funding from the National Institutes of Health (NIH) and the Department of Defense (DoD). His work bridges basic science and clinical applications, with particular emphasis on developing advanced therapeutics for muscle injuries and degenerative diseases. Through his lab, he mentors junior researchers in the fields of biomechanics, bioengineering, and regenerative medicine. Dr. Han leads the Han Lab, which focuses on skeletal muscle regeneration research. The lab employs a multidisciplinary approach combining biomaterials engineering, molecular biology, and advanced imaging techniques to develop novel strategies for enhancing muscle repair and preventing pathological changes following injury.

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +۵ مورد دیگر

João F. Mano is a Full Professor at the Department of Chemistry, University of Aveiro, and Director of the Doctoral Program on Biotechnology. He leads the COMPASS Research Group and serves as Vice-Director at CICECO - Aveiro Institute of Materials. His academic appointments include Invited Professor at University of Lorraine (France), Visiting Professor at KAIST (South Korea), and Adjunct Professor at Ajou University (South Korea). Education: PhD in Chemistry (1996, Technical University of Lisbon); D.Sc. in Tissue Engineering, Regenerative Medicine and Stem Cells (2012, University of Minho) Research Interests focus on Biomaterials for Regenerative Medicine , integrating Nanotechnology , Microtechnology , and Biofabrication . His group develops Bioinspired Materials using polymer chemistry, Decellularized Extracellular Matrix , and 3D Bioprinting to engineer Cell Microenvironments for therapeutic applications. Recent Publications highlight advancements in Human-Derived Hydrogels , Photopolymerizable Scaffolds , Magneto-Responsive Biomaterials , and Programmable Bioinks . Trends show emphasis on Organ-on-a-Chip integration, Smart Living Materials , and Green Bioprinting methodologies. Scientific Awards include: European Research Council Advanced Grants (2015, 2020) Fellow at IUPAC, European Academy of Sciences, and American Institute of Medical and Biological Engineering ERC Proof of Concept Grants Doctor Honoris Causa from University of Lorraine and Utrecht UNESCO Chair on Biomaterials George Winter Award (European Society for Biomaterials) Supervisions & Collaborations encompass 74+ MSc, 26+ PhD students, and 40+ postdocs. He co-founded METATISSUE and CELLULARIS Biomodels , and serves as Editor-in-Chief of Materials Today Bio .

Petra Schwilleمشاهده پروفایل

استاد

• Molecular Biophysics
• Cellular Biophysics
• Synthetic Biology
• +۵ مورد دیگر

Prof. Dr. Petra Schwille is a Director at the Max Planck Institute of Biochemistry and former C4 Professor of Biophysics at Dresden University of Technology . Her work spans molecular and cellular biophysics, synthetic biology, and single-molecule techniques. Academic disciplines: Natural sciences, biological sciences, physical sciences Key roles: Editorial Board member (Nature Methods, Biophysical Journal), Governing Council of Biophysical Society Research Focus includes membrane biophysics, protein interactions, and microfluidic systems. Her publications emphasize Fluorescence Correlation Spectroscopy (FCS) , receptor-ligand dynamics, and self-organization in bacterial cell division. Developed in vitro models for spatial regulation in cells Explored calmodulin availability and morphogen gradient formation Scientific Recognition includes prestigious awards like the Gottfried Wilhelm Leibniz Prize (2010) and the Biofuture grant (1998) . Max Planck Fellow (2005) Young Investigator Award (2003) Leadership & Service involves roles such as Dean of Studies for Nanobiophysics at TU Dresden and Vice Dean of the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) . She also contributes to editorial and advisory boards in biophysics and science policy.

Ardon Shorrمشاهده پروفایل

مدرس

• Science Communication
• Biology
• Mechanotransduction
• +۳ مورد دیگر

Ardon Shorr serves as Writing Seminar Faculty at Princeton University's Princeton Writing Program, based in office 313 New South. His position focuses on academic writing instruction within the university's core curriculum. Trained in experimental biology, Shorr specializes in explaining scientific complexity through science communication. His research background includes gravitational biology and mechanotransduction, with expertise in developing biological measurement devices. Current work emphasizes translating technical concepts for broader audiences. Publication trends reveal sustained investigation into cellular force sensing mechanisms, evolving from foundational gravitational transduction studies (2008) to innovative high-throughput embryonic research using mesofluidics (2019). This trajectory demonstrates integration of bioengineering approaches with developmental biology. No scientific awards, student advisees, research grants, or laboratory affiliations were documented in available materials.

Michael J. Mitchellمشاهده پروفایل

دانشیار

• Biomaterials Science
• Drug Delivery
• Cancer Therapy
• +۷ مورد دیگر

Michael J. Mitchell is an Associate Professor in the Department of Bioengineering at the University of Pennsylvania. His research focuses on overcoming biological barriers to drug delivery through biomaterials science, nanotechnology, and cellular engineering. Key areas include mRNA lipid nanoparticle development for cancer therapy, immunotherapy, genome editing, and regenerative medicine. His lab has pioneered placental-targeted drug delivery for in utero treatments and developed scalable microfluidic manufacturing processes for vaccines. Education: PhD in Bioengineering (University of Pennsylvania) Postdoctoral Training in Nanomedicine Research Interests: Dr. Mitchell’s work integrates biomaterials with biological systems to improve drug delivery efficiency. Current projects include: Design of lipid nanoparticles for mRNA and CRISPR delivery Targeted therapies for cancer metastasis and cardiovascular disease Placenta-specific drug delivery systems for maternal-fetal health Bioengineered immune cell therapies using mRNA Recent Achievements: In 2021, his lab published breakthrough work on lipid nanoparticles improving mRNA vaccine stability, featured in Penn Today and MIT Technology Review . Collaborations with CHOP and Penn Medicine have advanced in utero mRNA delivery for congenital diseases. Awards & Grants: Recipient of NIH grants for nanomedicine research and industry partnerships for vaccine development. Active in translational projects with startup companies for clinical nanotechnology applications. Labs & Teams: Lead of the Mitchell Lab at Penn Engineering, which includes over 20 researchers focusing on nanomedicine, biomaterials, and clinical translation.

David Lydon-Staleyمشاهده پروفایل

دانشیار

• Health Communication
• Substance Use
• Media Effects
• +۷ مورد دیگر

David Lydon-Staley is an Associate Professor at the Annenberg School for Communication, University of Pennsylvania, where he serves as Principal Investigator of the Addiction, Health, & Adolescence (AHA!) Lab. His research integrates neuroscience with communication science to examine substance use, media effects, and curiosity using fMRI, ecological momentary assessment, and network analysis. Education includes a Ph.D. in Human Development & Family Studies from The Pennsylvania State University, an M.S. from Penn State, an M.F.A. in Creative Writing from Drexel University (2025), and a B.A. in Psychology and English Literature from Trinity College Dublin. Research focuses on three interconnected areas: curiosity in media environments and health communication, media engagement in emotion dynamics, and substance use through dynamic network perspectives. Work emphasizes intensive longitudinal measurement of brain-behavior interactions during daily life. Recent publications (2023-2025) predominantly explore tobacco behavior, neural mechanisms of addiction, curiosity modulation, and social media's emotional impacts. Articles demonstrate consistent themes: fMRI analysis of inhibitory control, real-time geospatial tracking of smoking triggers, curiosity-based health messaging, and emotion regulation networks. Research has been supported by the National Institute on Drug Abuse, Jacobs Foundation, International Society for Behavioral Development, Center for Curiosity, and Brain & Behavior Research Foundation. Leads the Addiction, Health, & Adolescence (AHA!) Lab investigating substance use through network science approaches. Collaborates with the Complex Systems Lab at Penn's Department of Bioengineering.