- Organic Chemistry
- Nucleoside Chemistry
- Catalysis
- +۳ مورد دیگر
Mahesh Lakshman is a Professor in the Department of Chemistry and Biochemistry at the City College of New York (CUNY). His research focuses on nucleoside chemistry, catalytic methodologies, and the synthesis of novel organic compounds with applications in medicinal chemistry and drug development. He has contributed extensively to the development of new synthetic routes for modifying nucleosides, including approaches for functionalizing purine and pyrimidine bases through C-N and C-C bond formation. His expertise includes metal-catalyzed cross-coupling reactions, directed arylation, and the use of hypervalent iodine reagents. He has explored catalytic systems for reducing organic compounds without external hydrogen gas, advancing green chemistry practices. His work spans nucleoside analogs for antiviral therapies (e.g., molnupiravir) and peptidomimetics based on saturated azaheterocycles. Publications highlight his focus on mechanistic studies, with recent work addressing aroylation of purine nucleosides and the synthesis of carbazolones via nitrene insertion. Despite over 50 publications since 1994, no specific awards or grants are explicitly listed in the provided text. His research often involves collaborations leveraging advanced spectroscopic techniques like NMR for product characterization.











