جست‌وجوی استاد و پژوهشگر

• Forensic Genetics
• Molecular Biology
• DNA Analysis
• +۳ مورد دیگر

Johannes Hedman serves as an Adjunct Senior Lecturer at the Division of Biotechnology and Applied Microbiology within Lund University's Faculty of Engineering. His research is centered on forensic DNA applications, with 39 research outputs including articles and a doctoral thesis compilation. He actively collaborates with the Swedish Police Authority as Principal Investigator for the ongoing 'Forensic DNA Analysis' project (2023-2026) and has supervised doctoral research in forensic DNA inhibition mechanisms. Research Interests: His expertise spans forensic genetics, molecular biology, and DNA analysis, with emphasis on STR/SNP sequencing technologies for criminal investigations. Key specializations include overcoming PCR inhibition, analyzing degraded DNA, developing ultrasensitive sequencing methods (e.g., SiMSen-Seq), and studying DNA transfer dynamics including shedder status consistency under environmental stressors. His work bridges biotechnology with forensic science to enhance evidence reliability. Publication Trends: Recent articles (2023-2025) demonstrate a focused trajectory in forensic DNA sequencing advancements. Key themes include proficiency testing for STR/SNP sequencing (2025), DNA quality assessment for whole genome sequencing (2024), and ultrasensitive methods for low-template samples (2024). His research consistently addresses forensic challenges like inhibition mechanisms and environmental effects on DNA transfer, leveraging deep sequencing and molecular identifiers to boost accuracy and sensitivity in criminal casework. Scientific Awards: No scientific awards, prizes, or fellowships are documented in the provided information. Advising and Grants: Hedman supervised Sidstedt, M.'s doctoral dissertation on 'PCR inhibition mechanisms in forensic DNA analysis' (2014-2019). He currently leads the Swedish Police Authority-funded project 'Forensic DNA Analysis' (2023-2026) as Principal Investigator. His academic engagement includes chairing invited talks like the 2024 presentation on DNA-based microbial water monitoring, reflecting applied interdisciplinary work. Labs and Teams: He operates within Lund University's forensic DNA research team at the Division of Biotechnology and Applied Microbiology, collaborating internationally across multiple jurisdictions. His network includes forensic laboratories, police authorities, and microbiology researchers, particularly evident in the 2025 interlaboratory proficiency study and environmental DNA monitoring activities.

Jeff Gellesمشاهده پروفایل

استاد

• Single-molecule biochemistry
• Transcription and RNA processing
• Cytoskeletal networks
• +۳ مورد دیگر

Jeff Gelles is the Aron and Imre Tauber Professor of Biochemistry and Molecular Pharmacology at Brandeis University. His research focuses on single-molecule biochemistry and biophysics, particularly in gene expression, transcription regulation, and cytoskeletal network dynamics. He employs advanced single-molecule light microscopy and CoSMoS techniques to study molecular machines in reconstituted systems and cell extracts. Education B.A., Harvard University Ph.D., California Institute of Technology Key Research Areas Transcription and RNA processing Cytoskeletal organization Interdisciplinary approaches combining physical chemistry, Bayesian machine learning, and mathematical modeling His lab develops methods to address the "crowd noise problem" in conventional biochemical studies by observing individual molecular complexes in real time. Recent publications highlight mechanisms of RNA polymerase recycling, σ70 retention during transcription, and DNA replication regulation. Lab members are affiliated with Brandeis' Biochemistry and Biophysics, Physics, and Quantitative Biology programs.

• Immunology
• Autoimmune Diseases
• RNA Biology
• +۴ مورد دیگر

Tom is a Professor and current Chair of the Department of Psychology at the College of Arts and Science. He previously served as Director of Graduate Studies for three terms. His research focuses on immunology and molecular mechanisms underlying autoimmune diseases, RNA biology, and neurodegenerative disorders. Key research areas include T-cell differentiation pathways in juvenile idiopathic arthritis, RNA editing deficiencies in Alzheimer’s and multiple sclerosis, and cytokine signaling in inflammatory conditions. He has pioneered methods for mRNA synthesis from DNA templates and developed therapeutic approaches targeting IL-26 in cancer and graft-versus-host disease. Tom’s recent work demonstrates how reduced Alu RNA editing contributes to neuroinflammation and viral pathogenesis. His interdisciplinary approach bridges immunology, neurology, and molecular biology to address complex disease mechanisms. Over 150 publications span immunotherapies, biomarker discovery, and gene regulation studies in autoimmune contexts. His research has advanced understanding of cytokine networks in chronic inflammatory diseases and identified novel therapeutic targets for cancer and multiple sclerosis. Current efforts focus on translating RNA-based therapies into clinical applications.

• Inorganic Chemistry
• Coordination Chemistry
• Materials Science
• +۴ مورد دیگر

Carmel Abrahams is a Senior Lecturer in the Department of Biochemistry at La Trobe University. She holds a PhD from Monash University and has an ORCID identifier 0000-0001-6292-2471. Her research focuses on coordination chemistry, structural characterization of metal complexes, and their applications in environmental and biomedical fields. Key interests include synthesis of coordination polymers, antimicrobial activity assessment, and dye/iodine adsorption studies. She has collaborated extensively with researchers like A. Beheshti on structural and functional properties of metal-based materials. Her publications span from 1994 to 2023, emphasizing innovative designs of coordination networks with tailored functionalities. Recent work highlights include high-selectivity photocatalytic degradation systems and transition programs for STEM students. While no specific awards are listed, her contributions to inorganic chemistry are evident through her prolific publication record in journals like Journal of the Chemical Society Dalton Transactions and Applied Organometallic Chemistry . Abrahams' research integrates experimental and computational approaches, addressing both fundamental and applied aspects of materials science. Her team explores ligand design strategies to modulate structural properties and functional behaviors of coordination compounds.

• DNA Nanotechnology
• RNA Synthetic Biology
• Single-Molecule Biophysics
• +۲ مورد دیگر

Dr. Wooli Bae is Lecturer in Experimental Soft Matter Physics at the University of Surrey's School of Mathematics and Physics. He holds a PhD in Physics from KAIST and completed postdoctoral research at LMU Munich and Imperial College London. Research focuses on nucleic acid nanotechnology, including DNA origami, RNA-based synthetic circuits, and single-molecule biophysics. Work enables programmable biomolecular systems for applications in sensing, drug delivery, and synthetic biology. Developed innovative methods including RNA-based toggle switches, handhold-mediated strand displacement, and evanescent field techniques for fluorophore analysis.

• Molecular Biology
• Biotechnology
• Microbiology
• +۳ مورد دیگر

Joanna Morcinek-Orłowska is a PhD student and scientific employee at the Intercollegiate Faculty of Biotechnology of the University of Gdańsk and the Medical University of Gdańsk. She is affiliated with the Department of Structural Biology and the Department of Molecular Biology (Faculty of Biology). Her research focuses on molecular mechanisms of DNA replication, bacteriophage enzymes, and phage display technologies. She contributes to interdisciplinary projects involving biotechnology, microbiology, and structural biology. Her educational background includes a Master of Arts (M.A.), and she is currently pursuing a PhD in biotechnology. Research interests revolve around understanding bacterial DNA replication processes, the functional roles of bacteriophage-derived enzymes, and engineering thermophilic phage display systems for biotechnological applications. She also investigates protein interactions and metabolic pathways linked to bacterial growth and cell division. Publications highlight advancements in phage display methodologies and the exploration of novel DNA polymerases. Recent work emphasizes the structural and biochemical studies of phage enzymes, such as EfaS-271, and their roles in handling DNA secondary structures. Her research bridges fundamental biology with applied biotechnology, addressing challenges in enzyme engineering and therapeutic applications. No scientific awards or grants were explicitly listed in the provided materials. She is involved with the Institute of Biotechnology at the University of Gdańsk, contributing to collaborative research teams and lab activities.

• Virology
• Cancer Biology
• Vaccinology
• +۷ مورد دیگر

Dr. Christopher D. Richardson is a Professor and former Canada Research Chair (Tier I, 2006-2020) at Dalhousie University's Faculty of Medicine, with dual appointments in the Department of Microbiology & Immunology and Department of Pediatrics. His research bridges virology, cancer biology, and oncolytic virus therapy, focusing on virus-host receptor interactions. BSc, MSc, and PhD from University of British Columbia Postdoctoral training: Rockefeller University & NIH Research Focus: Molecular mechanisms of measles, canine distemper, hepatitis C, and B viruses, with emphasis on: Nectin 4/CD46 receptor interactions Oncolytic virus targeting of tumor cells Hepatitis C viral replication Vaccinology applications Paramyxovirus pathogenesis Humanized liver models for viral studies Scientific Awards: Canada Research Chair Tier I (2006-2020) IWK Health Centre Research Star of the Year (2012) Violet and Blythe Eagles Graduate Prize (1976) Bernard Fields Lecturer (2004) Active in CIHR and NIH grant panels (2011-2013), Richardson's work combines viral pathogenesis with translational medical applications, particularly in liver cancer and neurodegenerative disease models.

Patrick S. Doyleمشاهده پروفایل

استاد

• Microfluidics
• Complex Fluids
• Polymer Physics
• +۵ مورد دیگر

Patrick S. Doyle Patrick S. Doyle is the Robert T. Haslam (1911) Professor of Chemical Engineering at the Massachusetts Institute of Technology (MIT), affiliated with the Department of Chemical Engineering under the School of Engineering. His research focuses on microfluidics, complex fluids, polymer physics, and rheology with applications in drug delivery, environmental engineering, and biomaterials. He has pioneered innovations in hydrogel-based systems for pharmaceuticals and water treatment. Education Ph.D., Chemical Engineering, Stanford University, 1997 M.S., Chemical Engineering, Stanford University, 1993 B.S., Chemical Engineering, University of Pennsylvania, 1992 Research Interests Dr. Doyle’s work bridges chemical engineering and biotechnology, addressing challenges in: Design of stimuli-responsive materials (thermogels, nanoemulsions) Microfluidic fabrication of drug delivery systems Biofilm mechanics and bacterial behavior in marine environments High-resolution spatial profiling of microRNA in tissues Recent Research Trends Recent publications highlight advancements in: Hydrogel-based platforms for controlled release of antibodies and nanoparticles Engineered yeast systems for heavy metal remediation Zwitterionic hydrogels for multipollutant water treatment Topological control of DNA networks using confinement and flow Honors & Awards Notable recognitions include: Alpha Chi Sigma Award (2022) – AIChE’s highest research honor Multiple Singapore Research Professorships (2021, 2016, 2013) John Simon Guggenheim Fellowship (2009) Lab on a Chip Pioneers of Miniaturization Prize (2008) Grants & Advising Active grants include J-WAFS Seed Funding (2019) supporting water innovation. His Doyle Research Group has advised over 50 graduate students and postdocs, with notable alumni in academia and industry. Labs & Collaborations Leads the MIT Soft Matter Engineering Lab, collaborating with: Massachusetts General Hospital (cancer immunotherapy) Nanyang Technological University (water treatment) ESPCI Paris (DNA topology)

Richard Kiehlمشاهده پروفایل

استاد

• Nanoelectronics
• Spintronics
• Topological Insulators
• +۵ مورد دیگر

Richard Kiehl is a retired professor in the School of Electrical, Computer and Energy Engineering at Arizona State University (ASU), previously holding faculty positions at Stanford University, University of Minnesota, and University of California, Davis. He holds a Ph.D. from Purdue University (1974) and has extensive industry experience at Sandia National Laboratories, AT&T Bell Labs, IBM Research, and Fujitsu Laboratories. His research focuses on nanoscale electronics, molecular nanotechnology, spintronics, and topological insulators. He pioneered DNA-based self-assembly for nanoelectronics and led interdisciplinary initiatives like the Molecular Nanoscience Alliance (MONALISA) and the Functional Engineered Nano Architectonics (FENA) center. Education: Ph.D. (1974), M.S. (1970), and B.S. (1970) in Electrical Engineering from Purdue University. Research Interests: Nanofabrication, quantum devices, non-Boolean computing, and interdisciplinary applications of nanotechnology. Awards: Life Fellow of IEEE (2001), Louis John Schnell Professorship (Minnesota). His work spans corporate R&D, university leadership (e.g., Department Chair at UC Davis), and over 100 publications in journals like Nano Letters, Physical Review Applied, and Applied Physics Letters. He also served on technical committees for IEEE conferences and edited volumes on heterostructure devices.

Thomas Pfannschmidtمشاهده پروفایل

استاد

• Chloroplast Biogenesis
• Photosynthesis Regulation
• RNA Polymerase
• +۲ مورد دیگر

Thomas Pfannschmidt is Professor of Plant Physiology at Leibniz University Hannover's Institute of Botany. His research focuses on photosynthesis regulation, chloroplast biogenesis, and plant-environment interactions, with emphasis on plastid-encoded RNA polymerase and retrograde signaling mechanisms. Teaching covers Plant Physiology, Photobiology, Evolution, and Bioinformatics. Current research investigates evolutionary adaptations in chloroplast transcription machinery and the role of polymerase-associated proteins in biogenesis.

Marc Delarueمشاهده پروفایل

استاد

• Structural Biology
• Computational Structural Biology
• DNA Repair
• +۱۲ مورد دیگر

Marc Delarue is a Professor and Head of Structure at the Laboratory of Architecture and Dynamics of Biological Macromolecules, part of the Department of Structural Biology and Chemistry at the Institut Pasteur in Paris, France. He leads multiple research projects focused on DNA repair, DNA replication, ion channels, and computational structural biology. Institution: Institut Pasteur School: Department of Structural Biology and Chemistry Department: Architecture and Dynamics of Biological Macromolecules Role: Head of Structure, Principal Investigator His research integrates experimental and computational approaches, including X-ray crystallography, cryo-EM, molecular dynamics, and electrostatic modeling, to understand macromolecular structure-function relationships. Key interests include DNA polymerases, NHEJ repair in cancer, ligand-gated ion channels, and the development of simulation software such as MinActionPath and NOMAD-Ref. The recent publications highlight a strong trend in structural mechanisms of DNA-processing enzymes, ion channel pharmacology, and computational modeling of macromolecular transitions. These works frequently appear in high-impact journals and involve collaborations across disciplines and institutions. Marc Delarue has mentored numerous PhD students and postdoctoral researchers, including Jérémie Piton, Jerome Gouge, Frederic Poitevin, and Leonardo Betancurt Anzola. His projects are supported by internal and transversal funding initiatives at the Institut Pasteur, such as the Cancer Initiative and INCEPTION convergence program, though specific grant names are not detailed. He is actively involved in software development for structural bioinformatics, leading projects like MinActionPath and NOMAD-Ref, which are used to simulate conformational changes and analyze dynamics in large macromolecular complexes.

Sylvia Spellerمشاهده پروفایل

استاد

• Scanning Probe Microscopy
• Surface Physics
• Nanoscience
• +۷ مورد دیگر

Sylvia Speller is a Professor of Physics at the University of Rostock, where she leads research in nanoscale physical, molecular, and biological processes. She is affiliated with the Institute of Physics and has previously held a professorship at Radboud University Nijmegen, where she directed NanoLab Nijmegen, fostering academic-industry collaboration in nanoscience and technology. PhD in Physics, University of Osnabrück (1995) Habilitation in Physics (2002) Postdoctoral research in Eindhoven and Leuven Full Professor, Radboud University Nijmegen (2001–2012) Professor of Physics, University of Rostock (2012–present) Her research focuses on understanding and controlling nanoscale processes through the development and application of scanning probe microscopy methods. Key areas include energy transfer, chemical reactions, and biophysical interactions at surfaces involving metal nanoparticles, molecular aggregates, and proteins. She investigates systems under complex environments, adapting SPM techniques for specific experimental conditions. Analysis of her recent publications reveals a strong emphasis on scanning probe microscopy , particularly STM and AFM, applied to porphyrin assemblies , quantum dots , biomolecular interactions , and surface nanostructures . Her work bridges physics, chemistry, and biology, with applications in nanotechnology and materials science. She has contributed significantly to understanding molecular self-assembly, mechano-catalysis, and single-molecule force spectroscopy. Her scientific contributions have been published in high-impact journals such as Nature Nanotechnology , Physical Review B , Nano Letters , and Langmuir . While no specific awards are listed in the provided text, her sustained publication record and leadership roles indicate significant recognition in the field. Sylvia Speller teaches advanced physics courses including Experimental Physics VI (Nuclei and Particles), Surfaces and Nanostructures, and a Seminar on Scanning Probe Microscopy. She has advised multiple students and collaborators on projects involving molecular imaging, surface dynamics, and nanoscale characterization. Her research has been supported by interdisciplinary grants, particularly in nanoscience and biomaterials, though specific funding sources are not detailed here. She leads a research group focused on scanning probe techniques and has been instrumental in initiatives like the Advanced Scanning Probes for Innovative Nanoscience and Technology (ASPRINT). Her lab emphasizes method development and real-time imaging of dynamic processes at solid-liquid interfaces, contributing to both fundamental science and technological applications.

Abdenour Soufiمشاهده پروفایل

مدرس ارشد

• Chromatin Structure
• Cellular Reprogramming
• Induced Pluripotent Stem Cells
• +۴ مورد دیگر

Abdenour Soufi serves as a Senior Lecturer in the School of Biological Sciences at the University of Edinburgh, leading research within the Centre for Regenerative Medicine and Institute for Regeneration and Repair. His laboratory investigates chromatin structure dynamics and cellular identity mechanisms with focus on developing safe reprogramming technologies for regenerative medicine. Dr. Soufi's research centers on chromatin structure and cellular identity , specifically examining how reprogramming factors (Oct4, Sox2, Klf4, c-Myc) convert fibroblasts to induced pluripotent stem cells. His group discovered that OSKM factors interact differently with fibroblast genomes compared to embryonic stem cells and face barriers accessing critical genomic regions. This foundational work drives their current efforts to engineer synthetic reprogramming factors that avoid tumorigenic risks associated with conventional methods. Analysis of his 12 publications (2014-2024) reveals consistent focus on nucleosome dynamics , transcription factor binding mechanisms , and cellular reprogramming barriers . His 2024 Nature paper demonstrates how nucleosome topology guides enhancer binding, while earlier work established how pioneer factors target partial DNA motifs on nucleosomes. Research spans fundamental chromatin biochemistry to translational applications in cancer and regenerative medicine. Scientific Awards and Recognition: MRC Career Development Award University of Edinburgh Chancellor's Fellowship Darwin Trust of Edinburgh Fellowship Diabetes Research & Wellness Foundation Grant Dr. Soufi actively supervises six PhD students including Katharine Furlong and Michael O'Dwyer, and collaborates extensively with Edinburgh colleagues (Chambers, Kaji, Lowell) and international partners (Buganim, Jauch, Skoultchi). His research receives funding from CRUK, EPSRC, MRC, and BBSRC. The Soufi group maintains strong ties with the Edinburgh Mammalian Synthetic Biology Research Centre and focuses on developing clinically viable reprogramming technologies through interdisciplinary approaches combining biochemistry, genomics, and synthetic biology.

• Proton Therapy
• Head and Neck Cancer
• Oropharynx Carcinoma
• +۳ مورد دیگر

Wens Kong is a Researcher in the Radiotherapy department at Erasmus University Medical Center, specializing in advanced proton therapy techniques. Their work focuses on optimizing treatment planning for head and neck cancers through computational innovations. Research interests center on Proton Therapy (100% fingerprint match), with significant contributions to Head and Neck Cancer (35%), Oropharynx Carcinoma (24%), and Treatment Planning (19%). Key methodologies include Bragg Peak engineering, DNA template modeling, and reduction of xerostomia through precision beam targeting. Current work emphasizes automated optimization systems for improving dose distribution while minimizing side effects. Recent publications demonstrate a strong trend toward fully-automated multi-criterial optimization systems, particularly for oropharyngeal cancer treatment. Research consistently addresses lateral dose penumbra reduction, robust treatment planning validation, and sparsity-induced computational acceleration - all aimed at enhancing proton therapy precision while maintaining clinical efficiency. Collaborations include prominent researchers at Erasmus MC: Huiskes M., Habraken S.J.M., Astreinidou E., Rasch C.R.N., Heijmen B.J.M., and Breedveld S. The research network shows significant international collaboration in medical physics and radiation oncology.

• Cancer Research
• Cell Biology
• Nanotechnology
• +۳ مورد دیگر

Yasuko Antoku is a Researcher at the Biotech Research & Innovation Centre (BRIC) within the Faculty of Health and Medical Sciences at the University of Copenhagen. Located at Ole Maaløes Vej 5 in Copenhagen, she has maintained an active research career from 2008 through 2024, contributing to numerous high-impact publications across multiple disciplines. Her research interests span cancer biology, nanotechnology, and developmental processes, with particular expertise in advanced imaging techniques and nanomaterial applications. Dr. Antoku's work demonstrates significant interdisciplinary integration, bridging molecular biology with innovative imaging technologies to address complex biological questions in cancer development and tissue regeneration. Analysis of her publication history reveals an evolution from foundational nanotechnology work (2008-2010) to more recent cancer biology and developmental research (2019-2024). Her contributions consistently focus on cellular dynamics, imaging methodologies, and molecular mechanisms underlying disease processes. Scientific Recognition Her 2008 paper in the Journal of the American Chemical Society has received over 825 citations Multiple publications featured in high-impact journals including Nature Cell Biology and Nature Communications Research highlighted across various news outlets and social media platforms As a member of BRIC's Core Facilities, Dr. Antoku provides specialized expertise to the broader research community while maintaining her own research trajectory. Her collaborative approach is evident in her extensive co-authorship network spanning multiple institutions and research domains.