جست‌وجوی استاد و پژوهشگر

Douglas Bishopمشاهده پروفایل

استاد

• Meiosis
• Homologous Recombination
• DNA Repair
• +۳ مورد دیگر

Douglas Bishop is a Professor in the Department of Radiation and Cellular Oncology at the University of Chicago's Biological Sciences Division. His research focuses on the biochemical and molecular mechanisms of homologous recombination during meiosis, with a particular emphasis on the functional interplay between Dmc1 and Rad51 proteins. He has pioneered immunostaining techniques to visualize recombination complexes and employs super-resolution microscopy for structural analysis. PhD in Cell and Developmental Biology from Harvard University B.A. in Biology from Amherst College His research interests span meiotic recombination, homology-directed DNA repair, genome stability in cancer, and small molecule modulators of Rad51. Key projects include biochemical reconstitution of Dmc1 activity, analysis of recombinosome architecture, and development of tumor-targeted therapies using Rad51-stimulatory compounds like RS-1. The 15 most recent publications (2024-2015) cover meiotic DNA repair mechanisms (87%), cancer biology (33%), and immunology (13%). Common subtopics include DSB regulation, recombinase function, ATPase activity, synaptonemal complex interactions, and chemical modulation of DNA repair pathways. NIH R35GM134942 (2020-2025): Mechanism of Dmc1-mediated Meiotic Recombination NIH R03CA205518 (2016-2018): Separating Rad51 functions in repair vs replication NIH R01GM050936 (1994-2020): Meiotic interactions of Dmc1 Bishop's lab develops protocols for yeast chromosome spreading, immunostaining, and fluorescent D-loop assays. His work demonstrates Rad51's dual role in mitotic DNA repair and meiotic recombination, with implications for cancer therapy through Rad51 overexpression targeting.

Vijaykumar Veerappanمشاهده پروفایل

دانشیار

• Molecular Genetics
• Symbiotic Nitrogen Fixation
• Plant Genomics
• +۳ مورد دیگر

Vijaykumar Veerappan serves as an Associate Professor in the Biology Department at Eastern Connecticut State University, where he maintains an active research program focused on molecular mechanisms in plant systems. His office is located in Science Room 357, with regular office hours scheduled throughout the week for student engagement. Dr. Veerappan's research centers on the molecular genetics of symbiotic nitrogen fixation in Medicago truncatula and the genetic regulation of seed developmental programs. His work bridges plant genomics, molecular biology, and agricultural applications, with particular emphasis on understanding genetic pathways that could enhance sustainable crop production through improved nitrogen fixation efficiency. Analysis of his publication record spanning 2005-2023 reveals consistent contributions to plant molecular genetics, with increasing focus on genomic approaches to study symbiotic relationships and seed development. His recent work demonstrates methodological innovation in aeroponic systems and genome sequencing techniques, while maintaining core interest in legume-rhizobia interactions and epigenetic regulation of plant development. His educational background includes a Ph.D. in Biology from Texas Tech University, an M.Phil. from the Hong Kong University of Science and Technology, and agricultural degrees (M.Sc. and B.Sc.) from Annamalai University in India. Prior to his current position, he completed postdoctoral training at the University of North Texas and Oklahoma State University. Teaching responsibilities include Genetics, Molecular Genetics, and Genetics and Society courses, reflecting his commitment to both technical and societal aspects of genetic science. While no formal advising relationships or grant information is documented in the provided materials, his laboratory work clearly involves collaborative research with multiple co-investigators across various institutions.

Julian Glosمشاهده پروفایل

پژوهشگر

• Community Ecology
• Amphibian Ecology
• Conservation Biology
• +۷ مورد دیگر

Dr. Julian Glos is a Research Associate at the University of Hamburg in the Department of Biology under the Faculty of Mathematics, Computer Science and Natural Sciences . His research focuses on community ecology of amphibians in Madagascar and Germany. Research Interests: Species spatial-temporal distribution Predator-prey dynamics Community assembly rules Ecological and anthropogenic gradients Climate change impact prediction Functional diversity analysis Scientific Projects: Hyperdiverse larval communities in Madagascar Biodiversity loss and fragmentation effects Amphibian conservation in Elbe floodplains Anthropogenic forest use impacts Methodologies: DNA barcoding for species identification Stable isotope analysis for trophic ecology Larval morphological studies Field surveys in tropical ecosystems Experimental habitat modeling

• Nanoscale Assembly
• Soft Matter
• Polymer Science
• +۳ مورد دیگر

Oleg Gang is a Professor in the Department of Chemical Engineering and Department of Applied Physics and Applied Mathematics at Columbia University since 2016, and Group Leader for the Soft Matter and Biomaterials Theme at Brookhaven National Laboratory's Center for Functional Nanomaterials since 2008. His work bridges nanotechnology, soft matter physics, and biomaterials with emphasis on programmable nanoscale assembly. His educational background includes MS and PhD in Physics from Bar-Ilan University, Israel (thesis: Structure of inner-shell electron levels in transition metals ; dissertation: Surface Ordering in Chain Molecules ), followed by postdoctoral research at Harvard University's School of Engineering and Applied Sciences on Liquids on nanostructured surfaces . Gang's research centers on DNA-guided assembly of nanoparticles into precise 2D/3D architectures, investigating phase behavior, optical properties, and mechanical resilience of these systems. He pioneers synchrotron-based X-ray methods to probe soft-hybrid material interfaces, with applications spanning nanophotonics, biomedicine, and advanced materials design. His group explores how bioencoding and geometric factors govern nanostructure formation and functionality. Recent publications demonstrate consistent innovation in 3D nanoparticle lattice visualization, DNA-engineered phase regulation, and resilient nanomaterial frameworks, revealing fundamental principles of programmable matter. These works highlight interdisciplinary convergence of nanoscience, biophysics, and materials engineering. Scientific recognition includes: Inventor of the Year, Battelle Award (2016) Top 10 Scientific Advances of 2016 at Brookhaven National Laboratory (2016) Fellow, American Physical Society (2014) Science and Technology Award for Outstanding Achievements, Brookhaven (2011) Gordon Battelle Prize for Scientific Discovery (2010) As Group Leader at the Center for Functional Nanomaterials, Gang directs research leveraging DOE facility resources including synchrotron light sources. His team develops novel characterization techniques and assembly strategies to advance nanomaterial applications in energy, medicine, and quantum technologies, maintaining strong Columbia University-Brookhaven collaborations.

• DNA Nanotechnology
• Self-Assembly
• Nanomaterials
• +۲ مورد دیگر

Brian Minevich serves as a Research Associate in the Materials Science, Soft/Bio Materials group at Brookhaven National Laboratory's Center for Functional Nanomaterials (CFN), operating under the Energy & Photon Sciences Directorate. His research integrates DNA nanotechnology with advanced materials synthesis to engineer functional nanostructures. His academic credentials include: Ph.D. in Chemical Engineering from Columbia University (2024) M.Phil. in Chemical Engineering from Columbia University (2020) M.S. in Chemical Engineering from Columbia University (2018) B.E. in Chemical Engineering from Stevens Institute of Technology (2016) Minevich specializes in DNA origami techniques and metallic nanoparticle self-assembly, utilizing small-angle X-ray scattering (SAXS) for structural characterization. His work manipulates DNA-mediated interactions to control phase behavior and morphology in nanomaterials, with applications spanning nanomedicine, quantum devices, and biomaterials engineering. This interdisciplinary approach bridges chemistry, physics, and biological engineering to create programmable nanoscale architectures. His publication record reveals consistent innovation in DNA-directed assembly methods, particularly in controlling inter-particle interactions for tailored nanoparticle superlattices and 3D frameworks. Recent work emphasizes multi-sequence encoding for precise nano-chamber engineering and superconducting nanoscale architectures, demonstrating strong convergence of synthetic biology and materials science. Recognition includes: 2023 MRS Outstanding Graduate Student Award No information is available regarding student advising or specific grant funding. His research leverages CFN's state-of-the-art facilities within the Soft/Bio Materials team, which focuses on the intersection of soft matter physics, biological systems, and nanofabrication to develop next-generation functional materials.

• Soft Matter
• Nanomaterials
• Self-Assembly
• +۶ مورد دیگر

Yugang Zhang is a Staff Scientist specializing in Soft/Bio Materials at Brookhaven National Laboratory's Center for Functional Nanomaterials (CFN) and National Synchrotron Light Source II (NSLS-II), positions held since 2019 and 2015 respectively. His expertise centers on synchrotron-based X-ray scattering techniques for characterizing soft matter and bionanomaterials. Dr. Zhang's educational background includes: Ph.D. in Condensed Matter Physics from the Chinese Academy of Sciences (dissertation: 'Hierarchical controlled synthesis, morphology and property modulation of zinc-based I-VI semiconductor Nanomaterials') Postdoctoral research at CFN focused on 'Programmable self-assembly of nanoparticle superlattices' His research program develops advanced characterization methods using synchrotron X-ray scattering to investigate nanoscale self-assembly , dynamics of active colloids in complex fluids , and advanced data analysis techniques . He actively supports user research and develops new capabilities at NSLS-II beamlines, with strong emphasis on coherent X-ray methodologies and programmable nanomaterial design. Analysis of Dr. Zhang's 10 publications (2015-2021) reveals consistent focus on nanoparticle superlattice engineering using DNA-mediated assembly, coherent X-ray scattering applications for dynamic studies, and functional nanomaterial design for applications ranging from nanocargo carriers to 3D printing. His work demonstrates interdisciplinary collaboration across materials science, physics, and biotechnology. Dr. Zhang maintains active development of scientific software tools through his GitHub profile (yugangzhang), with repositories focused on XPCS data analysis and hierarchical data visualization. He participates in CFN's Soft/Bio Materials group and NSLS-II beamline operations, contributing to facility capabilities for soft matter research.

Mariana Kozlowskaمشاهده پروفایل

پژوهشگر

• Materials Science
• Computational Chemistry
• Biophysics
• +۷ مورد دیگر

Dr. Mariana Kozlowska is a Group Leader and KIT Associate Fellow at the Institute of Nanotechnology, Karlsruhe Institute of Technology (KIT). She leads the DNA Unit of the Virtual Materials Design platform, focusing on multiscale modeling of soft matter and natural materials to understand molecular dynamics, assembly, and interfacial phenomena in chemistry, biology, and physics. Her research integrates density functional theory (DFT) , molecular dynamics simulations , and multiscale modeling to investigate spectroscopic properties, photophysical phenomena in metal-organic frameworks (MOFs) , molecular adsorption, and noncovalent interactions. Current projects include virtual design of chiral alignment materials and photoswitchable MOF conductance, supported by the Carl Zeiss Stiftung and DFG Priority Program. Dr. Kozlowska’s work has been recognized through grants like the Brigitte-Schlieben-Lange-Programm and 3D Matter Made to Order Cluster of Excellence. Her interdisciplinary approach bridges computational modeling with experimental validation, particularly in biomolecular assembly and functional materials design . She has also contributed to science communication via initiatives like Creative Discussions about Science and the ADAMED SmartUP program. Research Focus: Multiscale materials modeling, soft matter assembly, MOF electronic properties Key Collaborations: Prof. Burkhard Luy (Virtmat), Prof. Maria Andrea Mroginski (DAAD grant)

• Cryo-electron Microscopy (CryoEM)
• Cryo-electron Tomography (CryoET)
• Quantitative Image Processing
• +۶ مورد دیگر

Steven Ludtke is a Professor in the Biochemistry and Molecular Pharmacology department at Baylor College of Medicine . He serves as the Charles C. Bell Jr. Professor of Structural Biology, Director of the CryoEM/ET Core, Co-Director of the Center for Computational and Integrative Biomedical Research (CIBR), and Deputy Director of Advanced Technical Cores. His lab focuses on advancing cryo-electron microscopy (CryoEM) and tomography (CryoET) for high-resolution structural analysis of biological systems. Education: Ph.D. in Physics, Rice University (1996) M.A. in Physics, Rice University (1993) B.S. in Physics, California Institute of Technology (1990) Ludtke's research spans CryoEM/CryoET methodology , quantitative image processing , and structural studies of macromolecular assemblies, membrane proteins, and antibiotic resistance mechanisms. His group developed the EMAN software suite , widely used in the field with over 30,000 downloads. Recent work explores in-situ structural biology using CryoET, enabling visualization of biomolecules within native cellular environments. The 15 most recent articles highlight trends in computational CryoEM/ET tools (e.g., deep learning for variability analysis), structural elucidation of ion channels (IP3R) and efflux pumps (AcrAB-TolC), and applications to pathogens like Toxoplasma and Candida glabrata . Key themes include 3D reconstruction algorithms , subtomogram averaging , and in-situ macromolecular architecture . Scientific Awards include the Burton Medal (MSA, 2008), multiple NRSA fellowships, and recognition as Outstanding Lecturer in Quantitative and Computational Biosciences (2020, 2023). His leadership in the CryoEM field is further evidenced by roles in EMDataBank and EMX initiative . Ludtke's lab collaborates on diverse biological systems, from individual proteins to whole-cell analysis, and contributes to cancer research via the Dan L Duncan Comprehensive Cancer Center . His work bridges methodological innovation with biomedical applications, particularly in membrane biology and disease mechanisms.

Mary Prorokمشاهده پروفایل

استادیار

• Structural Biology
• Biochemistry
• Peptide Chemistry
• +۷ مورد دیگر

Dr. Mary Prorok is an Assistant Professor at the University of Notre Dame's College of Science, Department of Chemistry, since 1998. Her research focuses on structure-function relationships in peptides and proteins, particularly those containing gamma-carboxyglutamic acid (Gla), such as blood coagulation factors and neuroactive conantokins from marine snail venom. She also investigates plasminogen and angiostatin. Education: B.S. in Medicinal Chemistry (1982, SUNY Buffalo, magna cum laude) Ph.D. in Chemistry (1990, SUNY Buffalo) Postdoctoral Fellow at Brandeis University (NIH, 1990–1993) and Notre Dame (AHA, 1994–1997) Her work combines site-specific mutagenesis and peptide synthesis with biophysical methods (X-ray crystallography, NMR, SPR). Functional assessments include enzymology and electrophysiology in mice. Recent publications highlight her focus on conantokin peptides, Gla residues, and plasminogen interactions. Scientific Awards: American Heart Association Scientist Development Grant She has authored over 40 publications, with recent trends in neuropharmacology, hematology, and structural analysis.

Tatjana Kleinowمشاهده پروفایل

مدرس ارشد

• Geminivirus-host plant interaction
• Phytoviral diagnostics
• Molecular tools for plant virus monitoring
• +۷ مورد دیگر

Tatjana Kleinow is a Senior Lecturer at the University of Stuttgart , leading the Molecular Biology Unit within the Institute of Biomaterials and Biomolecular Systems. Her research focuses on geminivirus-host plant interactions , particularly the cell biological and molecular mechanisms of intra- and intercellular virus transport, pathogenicity, and plant macromolecular trafficking. She also develops phytoviral diagnostics using nucleic acid-based methods and explores plant virus-based vectors for biotechnology and functional genome analysis. Habilitation in Plant Molecular Biology and Virology (2007) Doctorate (Dr. rer. nat., University of Cologne, 2000) Her work emphasizes posttranslational regulation of viral proteins, with contributions to understanding phosphorylation effects on viral movement and replication. She has pioneered isothermal amplification techniques for plant virus detection and investigated virus-induced stromule formation as a novel macromolecular transport route. Recent publications highlight her expertise in viral protein dynamics and host reprogramming. Kleinow serves as a Review Editor for Frontiers in Plant Science and has held leadership roles in academic committees. Her teaching includes courses in molecular biology, bionanotechnology, and scientific methodology for Technical Biology students.

• Genomics
• Structural Variation
• Cancer Biology
• +۳ مورد دیگر

Dr. Jan Korbel is a Senior Scientist and Group Leader at the European Molecular Biology Laboratory (EMBL) Heidelberg , with a joint appointment at EMBL-EBI . He serves as Interim Head of EMBL Heidelberg since April 2025 and leads the Data Science Centre since 2020. A faculty member of the ELLI Unit and an ERC Investigator since 2014, his research focuses on genomic structural variation , single-cell sequencing , and their roles in cancer and human evolution . PhD (2005): EMBL Heidelberg/Humboldt University Berlin Postdoctoral research: Yale University His work bridges computational biology and experimental genomics , with key contributions to long-read sequencing , haplotype-resolved assemblies , and pan-genome references . Recent articles demonstrate expertise in oncogenic structural variants , chromatin architecture , and global data-sharing frameworks like the Federated European Genome-Phenome Archive . Scientific awards : ERC Investigator status (2014) and leadership roles in major consortia (PCAWG, Human Genome Structural Variation Consortium). He developed tools such as MosaiCatcher , VISOR , and Alfred for structural variant analysis and alignment statistics.

• Powder Technology
• Molecular Dynamics Modeling
• Multiscale Modeling
• +۵ مورد دیگر

Bodhisattwa Chaudhuri is a faculty member in the Department of Pharmaceutical Sciences at the University of Connecticut's School of Pharmacy. His research bridges computational modeling and pharmaceutical manufacturing, focusing on multiscale approaches to materials science, drug delivery, and process optimization. Education: B.E. in Chemical Engineering (Jadavpur University), M.S. in Chemical Engineering (Indian Institute of Science), Ph.D. in Mechanical Engineering (New Jersey Institute of Technology), Postdoctoral Training in Chemical and Biochemical Engineering (Rutgers University) His work integrates Molecular Dynamics (MD) and Discrete Element Method (DEM) simulations with Computational Fluid Dynamics (CFD) to address challenges in pharmaceutical systems. Key areas include: Aggregation behavior of viral vectors like AAV8 AI/ML applications for biopharmaceutical process prediction 3D printing of tablets and freeze-thaw stability of biologics Tribotechnical challenges in powder systems The 15 most recent publications highlight his focus on computational modeling (MD, CFD, DEM) for pharmaceutical processes, machine learning applications in stability prediction, and multiscale studies of drug delivery systems like lipid nanoparticles and polymeric micelles. His work spans both fundamental research and industrial translation. Contact: bodhi.chaudhuri@uconn.edu | Personal Website

Fritz Sedlazeckمشاهده پروفایل

دانشیار

• Genomics
• Structural Variation Analysis
• Long-Read Sequencing
• +۳ مورد دیگر

Fritz Sedlazeck is an Associate Professor at the Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX. His research focuses on structural variation analysis, long-read sequencing, and bioinformatics, with applications in cancer genomics, neurogenetics, and pathogen characterization. He has developed computational tools like VACmap and DRAGEN for variant detection and alignment, and his work addresses challenges in tandem repeats, methylation patterns, and reference genome gaps. Research Interests: Structural variation in pediatric brain tumors and neurodevelopmental disorders Multiomics approaches to MECP2 Duplication Syndrome Technical innovations in long-read sequencing and variant calling Epigenetic regulation via DNA methylation Pathogen genomic characterization Recent Trends: His 2025 publications emphasize long-read sequencing for resolving complex genomic regions, benchmarking structural variants, and uncovering disease-relevant mutations. Key subfields include cancer genomics, neurogenetics, and computational methods for tandem repeats and methylation analysis. Affiliations: Baylor College of Medicine, Human Genome Sequencing Center.

Gloria Teresa Brea Calvoمشاهده پروفایل

دانشیار

• Cell Biology
• Molecular Biology
• Mitochondrial Diseases
• +۵ مورد دیگر

Gloria Teresa Brea Calvo is an Associate Professor in the Department of Physiology, Anatomy and Cell Biology at Universidad Pablo de Olavide , affiliated with the Andalusian Center for Developmental Biology (CABD) . Her research focuses on Mitochondrial Diseases , particularly Coenzyme Q Deficiencies , and she contributes to the Doctoral Programs in Cellular and Molecular Biology and Genetic Engineering . Research Pillars: Primary and Secondary CoQ Deficiencies Mechanisms of Mitochondrial Bioenergetics Oxidative Stress and Redox Signaling Mitochondrial Ribosome Assembly Key Contributions: Development of CRISPR/Cas9 Human Cell Models for COQ6 mutations Identification of Vanillic Acid as Bypass Therapy for CoQ Deficiencies Mechanistic Insights into ROS Signaling in Cardiomyopathy Selected Publications (2006–2020) analyze: Mitochondrial Respiratory Chain Organization Genotype-Phenotype Correlations in Pediatric Mitochondrial Disorders Metabolic Responses to Chemotherapy and Amino Acid Starvation

• Bioinformatics
• Genomics
• Computational Biology
• +۳ مورد دیگر

Pedro Manuel Martínez García is a researcher associated with the Centro Andaluz de Biología del Desarrollo (CABD) and affiliated with the Universidad de Málaga. His academic background includes a PhD in Bioinformatics, awarded in 2015 for work on computational tools analyzing plant-associated bacterial genomes. He has contributed to interdisciplinary projects combining genomics and machine learning. Research Interests: His work spans bioinformatics, genomics, and computational biology, focusing on plant-microbe interactions, chromatin architecture, and regulatory genomics. He has developed tools for predicting secretion systems in bacteria and analyzing 3D genome organization in developmental biology. Publications: Recent research highlights include applications of CRISPR-Cas technology in zebrafish, epigenomic studies of limb development, and comparative 3D genome analyses of retinal tissues. His work often bridges computational methods with experimental validation.