Gloria Teresa Brea Calvo

Gloria Teresa Brea Calvo is an Associate Professor in the Department of Physiology, Anatomy and Cell Biology at Universidad Pablo de Olavide, affiliated with the Andalusian Center for Developmental Biology (CABD). Her research focuses on Mitochondrial Diseases, particularly Coenzyme Q Deficiencies, and she contributes to the Doctoral Programs in Cellular and Molecular Biology and Genetic Engineering.

• Research Pillars:
  • Primary and Secondary CoQ Deficiencies
  • Mechanisms of Mitochondrial Bioenergetics
  • Oxidative Stress and Redox Signaling
  • Mitochondrial Ribosome Assembly
• Key Contributions:
  • Development of CRISPR/Cas9 Human Cell Models for COQ6 mutations
  • Identification of Vanillic Acid as Bypass Therapy for CoQ Deficiencies
  • Mechanistic Insights into ROS Signaling in Cardiomyopathy

Selected Publications (2006–2020) analyze:

• Mitochondrial Respiratory Chain Organization
• Genotype-Phenotype Correlations in Pediatric Mitochondrial Disorders
• Metabolic Responses to Chemotherapy and Amino Acid Starvation