جست‌وجوی استاد و پژوهشگر

Julian Guttmanمشاهده پروفایل

استاد

• Cellular Microbiology
• Bacterial Pathogenesis
• Cytoskeleton Alterations
• +۳ مورد دیگر

Julian Guttman is a Professor in the Department of Biological Sciences at Simon Fraser University (SFU), specializing in Cellular Microbiology. He serves as Editor-in-Chief of the journal Cytoskeleton . His research focuses on bacterial infections' molecular mechanisms, particularly how pathogens like Listeria monocytogenes , E. coli , and Salmonella manipulate host cell cytoskeletons (actin, microtubules) to invade, spread, and cause disease. Key areas include actin-based motility, pathogen-induced membrane protrusions, and therapeutic development. His lab actively recruits undergraduate, graduate students, and postdoctoral fellows. Education: BSc (University of Western Ontario), MSc and PhD (University of British Columbia). He has published extensively on host-pathogen interactions, with recent work on Listeria's caveolin-mediated spreading, KATNAL1-driven microtubule disassembly by Klebsiella, and cyclophilin A's role in Salmonella invasion. His work bridges microbiology, cell biology, and structural biology to combat infectious diseases.

Tomoyuki Tanakaمشاهده پروفایل

استاد

• Chromosome Segregation
• Mitosis
• Cell Cycle Regulation
• +۷ مورد دیگر

Professor Tomoyuki Tanaka holds the Chair of Cell and Molecular Biology at the University of Dundee within the School of Life Sciences . He serves as the Academic Lead of Dundee Imaging Facility (since 2018) and Deputy Head of the Division for Molecular Cell & Developmental Biology (since 2022). His research focuses on chromosome segregation mechanisms in mitosis and their implications in genetic diseases and cancer . Member of European Molecular Biology Organisation (EMBO, 2008–) Fellow of Royal Society of Edinburgh (2009–) Wellcome Trust Investigator (2020–) His lab investigates two key processes in early mitosis: chromosome reorganization (resolution and compaction of sister chromatids) and kinetochore-spindle interactions . These mechanisms are critical for preventing errors linked to aneuploidy, congenital disorders, and cancers . Using budding yeast as a model organism, his group combines genetic, proteomic, and imaging techniques to uncover conserved biological principles. Recent publications highlight discoveries in condensin exclusion during prophase , Aurora B kinase spatial regulation , and error correction mechanisms for accurate chromosome inheritance. The lab also contributes to in vitro reconstitution of chromosomal processes, including a 2021 breakthrough on chromosome positioning networks . 2020: Wellcome Investigator Award 2013: ERC Advanced Grant 2007: Hooke Medal (British Society for Cell Biology) 2000: EMBO Young Investigator He supervises PhD students and contributes to Level 3 undergraduate teaching (BS31006 Gene Regulation) and Honours research projects . His work aligns with UN Sustainable Development Goals for health and well-being through genetic disease research.

Dean R. Tolanمشاهده پروفایل

استاد

• Biochemistry
• Enzymology
• Molecular Genetics
• +۳ مورد دیگر

Dean R. Tolan is a Professor of Biology and Director of Undergraduate Studies at Boston University. His research focuses on the biochemical and genetic mechanisms underlying sugar metabolism, particularly the glycolytic enzyme aldolase and its role in hereditary fructose intolerance (HFI). He leads a laboratory investigating aldolase structure-function relationships, moonlighting functions in cell motility, and the pathophysiology of HFI using mouse models. His work integrates structural biology (X-ray crystallography, electron microscopy), genetic analysis, and metabolomics. Key research themes include: (1) Structural basis of aldolase isoforms' catalytic differences; (2) Genetic defects causing HFI and their clinical manifestations; (3) Evolutionary adaptation of aldolase moonlighting roles. He teaches core biochemistry courses (BI108, BB421/422, MB722). Notable achievements include pioneering studies on aldolase B knockout mice mimicking human HFI, and discoveries linking fructose metabolism to metabolic syndrome, cancer, and neurodegenerative diseases. His lab collaborates internationally on projects funded by NIH and other agencies.

Peter Matthiasمشاهده پروفایل

استاد

• Biochemistry
• Cell Biology
• Cell division
• +۷ مورد دیگر

Matthias Peter is a Professor of Biochemistry at ETH Zurich, leading research into mechanisms governing cell growth and division. His laboratory focuses on ubiquitin-dependent regulation of DNA replication and mitosis, and autophagy's role in cellular quality control. He chairs the Department of Biology (2011-2015) and holds leadership roles in Switzerland's research infrastructure, including Vice Chair of ScopeM's microscopy platform. His academic career includes roles at ISREC (1996-2002) and postdoctoral training at UCSF (1991-1996). Education: PhD in Biochemistry from ISREC (1991), ETH Zurich diploma in Gene Technology (1987). Research interests span molecular mechanisms of cell division, ubiquitin systems, and autophagy. Awards include ERC Advanced Grant (2011) and UBS Excellence in Research (2002). Leadership: Member of Swiss National Research Council, SNF selection committee, and SWTR council. Over 20 years of committee service in national research programs. His lab's work is published in top journals like Science, Nature, and Molecular Cell.

Emanuel Petricoinمشاهده پروفایل

استاد

• Proteomics
• Molecular Medicine
• Biomarker Discovery
• +۳ مورد دیگر

Emanuel Petricoin is a Professor and Co-Director of the Center for Applied Proteomics and Molecular Medicine (CAPMM) at George Mason University's School of Systems Biology, a position held since 2005 with prior leadership at the FDA-NCI Clinical Proteomics Program (1993-2005). His academic affiliation spans proteomics, molecular medicine, and precision oncology within GMU's research ecosystem. His educational background includes: Ph.D. in Microbiology from the University of Maryland, College Park (1990) Dr. Petricoin pioneers clinical proteomics for personalized therapy and biomarker discovery, with seminal work in cancer signaling pathways, tumor microenvironment analysis, and diagnostic assay development. His research integrates proteogenomics, phosphoproteomics, and functional protein analysis to address therapeutic resistance in breast and pancreatic cancers. As a translational scientist, he bridges laboratory innovation with clinical implementation through FDA-regulated platforms. Analysis of his 2024-2025 publications reveals dominant themes in proteogenomic tumor characterization, KRAS/HER2 pathway dynamics, and biomarker-guided immunotherapy. Key trends include spatial proteomics of tumor heterogeneity, extracellular vesicle-mediated signaling, and quantitative assessment of drug targets for precision oncology decision-making. The work consistently emphasizes clinical applicability through CLIA-certified assays and molecular tumor boards. His scientific recognition includes: University Professorship at George Mason University NIH Director’s Award FDA Distinguished Scientist Award 2015 Innovator of the Year Award GAP50 Top Virginia Entrepreneurs Nifty 50 Award American Society of Cytopathology Basic Research Award Roche Diagnostics/CLAS Distinguished Scientist Award Harvard University Leading Edge Award Dr. Petricoin drives research commercialization as co-founder of four biotech firms (Theranostics Health, Ceres Nanosciences, C-4 Diagnostics, Perthera) and co-inventor of 40+ patents. His editorial leadership spans Proteomics, Cancer Epidemiology Biomarkers and Prevention, and other high-impact journals. He actively shapes national initiatives as a HUPO founding member and Virginia Health Research Biosciences Corporation board representative. The CAPMM under his co-direction serves as a national hub for clinical proteomics, specializing in reverse-phase protein array (RPPA) technology, laser capture microdissection, and biomarker validation for direct patient care applications. The center integrates multi-omic data to advance personalized cancer therapy through industry partnerships and clinical trial support.

Michael Robertsمشاهده پروفایل

استاد

• Exercise Physiology
• Nutrition Science
• Skeletal Muscle Physiology
• +۲ مورد دیگر

Michael Roberts is a Professor in the School of Kinesiology at Auburn University, serving as Director of both the Molecular and Applied Sciences Laboratory and the Applied Physiology Laboratory. His research integrates nutrition and exercise science to investigate cellular biomarkers and whole-body physiological responses using cell culture, rodent models, and human studies. His primary research interests include Exercise Physiology , Nutrition Science , and Skeletal Muscle Adaptation , with emphasis on resistance training mechanisms, dietary supplementation, and molecular pathways underlying muscle hypertrophy/atrophy. His work employs advanced techniques in molecular biology to address questions relevant to athletic performance, aging, and clinical rehabilitation. Analysis of his recent publications reveals consistent focus on resistance training adaptations, creatine/nitrate supplementation, skeletal muscle remodeling, and microbiome-exercise interactions. His research demonstrates methodological diversity spanning cellular models, rodent studies, and human clinical trials, with particular attention to molecular mechanisms in aging populations and performance optimization. Dr. Roberts actively mentors through laboratory leadership roles, though specific student names aren't documented in provided materials. His editorial positions in physiology journals and frequent conference lectures indicate significant academic influence beyond direct research outputs. The Molecular and Applied Sciences Laboratory and Applied Physiology Laboratory form collaborative hubs for interdisciplinary research, utilizing techniques ranging from molecular analysis to whole-body physiological assessment. These facilities support investigations into exercise-nutrition interactions across diverse populations from athletes to older adults.

Bailly Aurélienمشاهده پروفایل

پژوهشگر

• Volatile organic compounds (VOCs) in plant-microbe interactions
• Molecular Plant-Microbe Interactions
• Induced systemic resistance in plants
• +۹ مورد دیگر

Dr. Aurélien Bailly is affiliated with the University of Zurich in the Department of Plant and Microbial Biology . His research focuses on volatile organic compounds (VOCs) as signaling molecules in plant-microbe communication, particularly in mediating growth and immune responses. Research Interests Molecular mechanisms of VOC-mediated cross-kingdom signaling Plant perception of bacterial volatiles Trade-offs between growth and immunity via phytohormones Functional characterization of microbial VOC bouquets Publication Trends highlight work on Arabidopsis thaliana and rhizobacteria, with emphasis on auxin transport , systemic resistance , and biocontrol strategies . His articles span disciplines including microbial ecology , plant physiology , and chemical biology .

Daniel M. Suterمشاهده پروفایل

استاد

• Cell Biology
• Neurobiology
• Nervous System Development
• +۶ مورد دیگر

Professor Daniel M. Suter is a faculty member in the Department of Biological Sciences at Purdue University, part of the College of Science. His research focuses on cellular and molecular mechanisms of axonal growth, guidance, and regeneration, using Aplysia and zebrafish models. He holds grants from NIH, the Indiana CTSI, and Purdue’s Ross-Lynn Research Fund. Suter earned his BS from ETH Zurich (1988) and PhD from the University of Zurich (1995), followed by postdoctoral training at Yale University. Education: Bachelor of Science in Biology, ETH Zurich, 1988 PhD in Biochemistry, University of Zurich, 1995 Postdoctoral Fellowship in Cellular Neurobiology, Yale University, 1995-2000 Research Interests: Suter’s lab investigates growth cone motility, cytoskeletal dynamics, ROS signaling, and axonal regeneration. Key projects include studying Nox-derived ROS in guidance, mechanosensing in growth cones, spinal cord injury drug screening in zebrafish, and bulk cytoskeletal flow. Awards: He has received the Graduate Student Mentoring Award (2021, 2017), Seed for Success Award (2020, 2013), and teaching/mentorship accolades. His work has been supported by grants like NIH R01 and Purdue’s Ross-Lynn Research Scholar Grant. Grants & Labs: Current grants include NIH funding for Nox2 signaling and Indiana CTSI support for light-sheet microscopy. The Suter Lab collaborates with Arvind Raman’s group on nanomechanical studies and participates in Purdue’s Neuroscience Institute and Integrative Biology initiatives.

• Molecular Biophysics
• Actin Cytoskeleton
• Molecular Motor Proteins
• +۳ مورد دیگر

Enrique M. De La Cruz is the William R. Kenan Jr. Professor of Molecular Biophysics and Biochemistry and Head of Branford College at Yale University. He specializes in the study of actin cytoskeleton dynamics, molecular motor proteins, and nucleotide signaling enzymes. His research integrates biophysical, biochemical, and structural approaches to understand cellular mechanisms. Dr. De La Cruz holds a Ph.D. from Johns Hopkins University and completed postdoctoral training at the University of Pennsylvania. He has been recognized with prestigious awards, including Fellowships from AAAS and ASBMB, and is an advocate for minority participation in STEM. His lab collaborates with researchers globally and employs advanced techniques like cryo-electron microscopy and computational modeling. Education: Bachelor's in Biology (Rutgers University) Ph.D. in Biochemistry, Cell & Molecular Biology (Johns Hopkins University) Research Interests: Actin filament mechanics and cation effects Molecular motor protein interactions Structural biology of cytoskeletal proteins Awards: Fellow, AAAS (2022) ASBMB Inaugural Fellow (2021) Cell Press's 100 Hispanic/Latinx Scientists (2020) Grants & Advising: NSF CAREER Award (2006) Extensive NIH-funded research Labs & Collaborations: De La Cruz Lab at Yale Cross-disciplinary partnerships with institutions like Institut Curie and ESPCI Paris Tech

Simon Mochrieمشاهده پروفایل

استاد

• Biophysics
• Condensed Matter Physics
• Single Molecule Biophysics
• +۷ مورد دیگر

Simon Mochrie is a Professor of Physics and Applied Physics at Yale University, affiliated with the Department of Physics within the Faculty of Arts and Sciences. His research focuses on experimental biophysics and condensed matter physics, with emphasis on chromatin dynamics, nuclear mechanics, and super-resolution microscopy. He holds a Ph.D. from MIT (1985) and has pioneered techniques such as optical tweezers and STED microscopy to study biological systems like the ubiquitin-proteasome system in yeast. Current projects include single-molecule measurements on nucleosomes and developing novel imaging methods like LIVE-PAINT for live-cell super-resolution imaging. Educations: Ph.D., Physics, MIT (1985) Research interests center on understanding how chromatin organization influences nuclear mechanics, with studies on heterochromatin condensation, cohesin-driven loop extrusion, and chromatin-envelope interactions. His lab develops advanced microscopy techniques to visualize protein dynamics and subnuclear structures in real time. Recent work explores diffusive states of membrane proteins and the role of phase separation in heterochromatin mechanics. His articles demonstrate a focus on interdisciplinary approaches, combining biophysical experimentation with computational modeling to elucidate fundamental mechanisms in cell biology and soft matter physics. Notable themes include the interplay between chromatin structure and nuclear stiffness, loop extrusion dynamics, and quantitative analysis of intrachromosomal contacts. Teaching contributions include developing introductory physics courses tailored for life sciences students, emphasizing applications in biology and medicine. He actively participates in STEM education initiatives, including collaborative research networks for graduate students in physical biology. The Mochrie Lab also emphasizes instrumentation innovation, such as building fast-scanning STED microscopes and reversible peptide-based imaging systems.

Elif Nur Fırat Karalarمشاهده پروفایل

دانشیار

• Cell Biology
• Cytoskeleton
• Centrosome
• +۷ مورد دیگر

Elif Nur Fırat Karalar is an Associate Professor at the Department of Molecular Biology and Genetics in Koc University 's School of Engineering and Natural Sciences. She serves as Director of the Sponsored Research Office and leads the Cytoskeleton Research Laboratory (CytoLab) , focusing on centriolar satellites, cilia, and their roles in developmental disorders and ciliopathies. Her lab has pioneered studies on microtubule-associated proteins like CCDC66 and CCDC15. PhD, University of California, Berkeley (2010) BSc, Bilkent University (2004) Her research explores membrane-less organelles, cellular signaling, cytoskeletal networks, and mitotic control mechanisms. Recent work includes ERC-funded projects on centriolar satellite homeostasis and TÜBİTAK grants dissecting ciliopathy protein functions in cell migration. She employs advanced techniques like U-ExM expansion microscopy and Superresolution Imaging Core (KUSIM) . Scientific recognitions include: 2024 - EMBO Member 2023 - ERC Starting Grant (second award) 2021 - TUBITAK Incentive Award 2019 - EMBO Young Investigator 2015 - ERC Starting Grant Elif Nur Fırat Karalar has successfully mentored multiple graduate students including Melis Dilara Arslanhan (PhD 2023) , Dila Gulensoy (MSc 2023) , and Şevket Onur Taflan (MSc 2021) . Her lab has received substantial funding from TÜBİTAK , EMBO , Royal Society , and IBG Science Medal . CytoLab actively participates in international conferences like Cilia2024 and organizes workshops such as the Advanced Imaging in Life Sciences series.

Zheng Zhouمشاهده پروفایل

استاد

• Cell Biology
• Molecular Genetics
• Developmental Biology
• +۳ مورد دیگر

Zheng Zhou is a Professor at the Verna and Marrs McLean Department of Biochemistry and Molecular Biology at Baylor College of Medicine. He is also a member of the Dan L Duncan Comprehensive Cancer Center. His research focuses on the molecular mechanisms of apoptotic and necrotic cell clearance in Caenorhabditis elegans , particularly the recognition, engulfment, and degradation of dying cells. Zhou holds a BS from Fudan University (Shanghai, China) and a PhD in Biochemistry from Baylor College of Medicine. He completed postdoctoral training at MIT and Baylor College of Medicine. His honors include the Norton Rose Fulbright Faculty Excellence Award (2018) and multiple fellowships, including from the Robert A. Welch Foundation and the Rita Allen Foundation. His research interests include understanding how dying cells expose 'eat-me' signals like phosphatidylserine and how phagocytic receptors (e.g., CED-1) mediate clearance. His lab uses genetic screens, live imaging, and molecular tools to study these processes in C. elegans . Recent work highlights roles of calcium signaling in necrotic cell recognition and autophagy-phagocytosis crosstalk in apoptotic cell degradation. Zhou has mentored numerous students and postdocs, including Omar Peña-Ramos (now a postdoc) and Jonathan Pickett. His lab is funded by grants such as an R35 MRA award and an RO1 supplement supporting research on lipid transfer proteins' roles in cell-cell interactions. Labs/Teams: The Zhou Lab at Baylor College of Medicine focuses on programmed cell death and clearance mechanisms. Collaborations include work on dynamin function and signaling pathways in phagocytosis.

Ulrike Kutayمشاهده پروفایل

استاد

• Nuclear envelope structure and biogenesis
• Nucleo-cytoplasmic transport
• Metazoan ribosome biogenesis
• +۳ مورد دیگر

Ulrike Kutay is a Full Professor of Biochemistry at ETH Zurich, Switzerland, with a research focus on nuclear biology and dynamics. Her work investigates nuclear envelope structure/function, ribosome biogenesis, and nucleo-cytoplasmic transport. Diploma in Biochemistry (Free University Berlin, 1992) PhD in Natural Sciences (Humboldt University Berlin, 1996) Research interests center on nuclear compartmentalization, including mitotic nuclear envelope breakdown and reassembly, ribosome assembly pathways, and the molecular mechanisms governing nuclear transport. Her lab explores how nuclear dysfunction contributes to diseases like ribosomopathies and cancer. Recent publications highlight her work on SUN/KASH proteins in nuclear envelope dynamics, ribosome biogenesis steps, and nuclear pore complex regulation. Collaborations with groups like the Spahn lab in Berlin underscore her interdisciplinary approach. EMBO Member (2010) Leopoldina Member (2012) ERC Advanced Grant (2012) As a mentor, she has supervised PhD students including Chiara and Roja. She actively participates in editorial boards, grant review panels (e.g., ERC, DFG), and institutional leadership roles at ETH Zurich and the Biochemistry Center Heidelberg. The Kutay Group at ETH Zurich combines proteomics, functional analyses, and structural studies to unravel nuclear processes, fostering a collaborative environment with recent achievements in mitotic nuclear disassembly and ribosome maturation research.

• Aging
• Animal Cell and Molecular Biology
• Genetically Modified Animals
• +۵ مورد دیگر

Judith West-Mays is a Professor in the Department of Pathology & Molecular Medicine at McMaster University . Her research focuses on: Molecular mechanisms of eye development and disease Role of transcription factors (AP-2β, AP-2α) in ocular morphogenesis Transforming Growth Factor Beta (TGF-β) signaling in epithelial-mesenchymal transition (EMT) Matrix Metalloproteinases (MMPs) in vision disorders Biomaterials for intraocular pressure management Key scientific contributions include: Elucidating AP-2β's role in trabecular meshwork formation and glaucoma Characterizing MMP-9's impact on aqueous humor drainage Developing conditional knockout mouse models for vision research Investigating YAP signaling in lens fibrosis Creating mucoadhesive micelles for glaucoma therapy Scientific awards : Brockhouse Canada Prize (2025) for interdisciplinary vision health research Teaching : Biomedical Engineering II (2018) at McMaster University. Collaborators include Taiyab, Sheardown, and Ball. Research hubs involve McMaster's interdisciplinary vision science team.

Douglas B. Cowanمشاهده پروفایل

پژوهشگر

• Cardiovascular Biology
• Mitochondrial Transplantation
• Ischemia-Reperfusion Injury
• +۳ مورد دیگر

Douglas B. Cowan serves as a Staff Scientist in the Cardiology and Vascular Biology Program at Boston Children's Hospital and holds an Associate in Surgery position at Harvard Medical School. His career spans over three decades with foundational training in genetics and molecular biology. B.Sc. in Honors Genetics, University of Western Ontario (1987) M.Sc. and Ph.D., University of Toronto (1989, 1994) Postdoctoral Fellowship, MRC-sponsored at Mount Sinai Hospital and Toronto General Hospital Dr. Cowan's research focuses on mitochondrial transplantation as a novel therapy for ischemia-reperfusion injury, with pioneering work demonstrating that autologous mitochondria injected during reperfusion significantly enhance cardiac recovery. His expertise bridges cardiovascular molecular biology , bioengineering , and translational surgical innovation , particularly in developing rapid mitochondrial isolation techniques and coronary delivery systems. Current investigations explore mitochondrial integration mechanisms in human cardiomyocytes using super-resolution microscopy. His publication portfolio includes 124 works with 4,810 citations and an h-index of 39, dominated by high-impact studies in PLoS ONE , American Journal of Physiology , and Journal of Thoracic and Cardiovascular Surgery . Key trends show evolution from foundational work on endothelial junctions (1999) to mitochondrial therapy dominance since 2009, with recent expansion into stroke applications (2023) and donor heart preservation (2022). Dr. Cowan collaborates extensively with James D. McCully (135+ co-publications), Pedro J. del Nido, and Ingeborg Friehs within the Cardiac Surgery Research Laboratory at Boston Children's Hospital. Current projects include optimizing mitochondrial delivery for pediatric cardiac applications and investigating metabolic mechanisms in fatty acid metabolism post-transplantation.