جست‌وجوی استاد و پژوهشگر

Waldemar Kolanusمشاهده پروفایل

استاد

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Joshua D. Rabinowitzمشاهده پروفایل

استاد

• Cellular Metabolism
• Metabolomics
• Systems Biology
• +۵ مورد دیگر

Joshua D. Rabinowitz is a Professor of Chemistry and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where he also serves as Director of the Ludwig Princeton Branch. His research focuses on achieving a quantitative, comprehensive understanding of cellular metabolism, with applications in both basic science and medical research. Dr. Rabinowitz's research interests span multiple areas of metabolism and systems biology: Quantitative analysis of metabolic networks and regulation Metabolomics and measurement of metabolite concentrations and fluxes Cancer cell metabolism and therapeutic targeting Metabolic regulation in microbes (E. coli, Saccharomyces cerevisiae) Biofuel production (focusing on Clostridium acetobutylicum) Metabolic impact of pathogen infection (viral infection of human cells) His laboratory has developed innovative methods for measuring cellular metabolites using state-of-the-art mass spectrometry technology and approaches for quantitating metabolic fluxes through isotope-labeling data interpretation. Analysis of recent publications reveals a strong focus on NAD+ metabolism, cancer metabolism, metabolic adaptations in disease states, and the intersection of metabolism with immunology and neuroscience, particularly in areas like T cell metabolism, Alzheimer's disease, and cardiac function. Dr. Rabinowitz has received recognition as a Highly Cited Researcher by Web of Science, indicating significant impact in his field. He advises several graduate students and has mentored numerous alumni, including Michel I. Nofal, Edmundo Leiva III, and Sean Hackett. His research is supported by multiple programs including NIH NHGRI Training Program and QCB Graduate Program. The Rabinowitz Lab operates at the intersection of chemistry, biology, and computational science, with all projects involving a mix of biological experiments, metabolomics, and computation to achieve their goal of a holistic understanding of cellular metabolism.

Ying Geمشاهده پروفایل

استاد

• Biological Mass Spectrometry
• Proteomics
• Metabolomics
• +۷ مورد دیگر

Ying Ge is a Professor at the University of Wisconsin–Madison, jointly appointed in the Department of Cell and Regenerative Biology and the Department of Chemistry. Her research integrates chemistry, biology, and medicine, focusing on advanced mass spectrometry-based proteomic and metabolomic technologies to address cardiovascular diseases. Education: B.S., Peking University (1997) Ph.D., Cornell University (2002) Ying Ge's work centers on developing ultra high-resolution mass spectrometry platforms for top-down proteomics and metabolomics, applied to systems biology studies of heart failure and regenerative medicine. Key projects include myofilament protein modification mapping, stem cell therapy evaluation, and biomarker discovery for cardiac conditions. The 15 most recent articles highlight her lab's methodological innovations (e.g., photocleavable surfactants, native mass spectrometry) and biological discoveries in AMPK structural heterogeneity, RBM20-mediated cardiotoxicity, and sarcomere-metabolism cross-talk during regeneration. These publications span proteomics, metabolomics, structural biology, and clinical applications.

Monica P. Colaiacovoمشاهده پروفایل

استاد

• Meiosis
• Chromosome dynamics
• DNA repair
• +۶ مورد دیگر

Dr. Monica P. Colaiacovo is a Professor of Genetics at Harvard Medical School, where she leads research in the Department of Genetics within the Blavatnik Institute. Her laboratory is located in the New Research Building in Boston, Massachusetts. Dr. Colaiacovo's research focuses on the molecular mechanisms of meiosis, chromosome dynamics, and DNA repair in the Caenorhabditis elegans model system. Her work examines how environmental toxicants impact germline function and reproductive health, with particular emphasis on chromosome segregation, recombination, and the synaptonemal complex. Her publications reveal a consistent research trajectory examining critical aspects of meiotic chromosome behavior, including double-strand break formation and repair, crossover designation, and chromosome movement during prophase I. Her laboratory has made significant contributions to understanding how environmental exposures like bisphenol A and phthalates disrupt normal meiotic progression and lead to germline dysfunction. Dr. Colaiacovo's work demonstrates strong interdisciplinary connections between basic chromosome biology, environmental health sciences, and reproductive medicine. Her research group employs advanced genetic, molecular, and imaging techniques to dissect the complex mechanisms ensuring accurate chromosome segregation during gamete formation. Her laboratory actively collaborates with researchers studying aging, DNA repair pathways, and environmental toxicology, as evidenced by publications spanning multiple high-impact journals including Nature, PLoS Genetics, and Genetics.

Jason Yiمشاهده پروفایل

استادیار

• Neuroscience
• Molecular Neuroscience
• Developmental Neuroscience
• +۶ مورد دیگر

Dr. Jason Yi is an Assistant Professor of Neuroscience at Washington University School of Medicine (WashU Medicine). His research focuses on understanding the molecular pathways that shape nervous system development and function, with particular emphasis on autism spectrum disorders (ASD). He leads the Yi Lab, which investigates the role of the ubiquitin ligase UBE3A in the brain and its implications for neurodevelopmental disorders. Dr. Yi received his BS in Biochemistry and Molecular Biology from Dickinson College in 2001 and his PhD in Pharmacology from Duke University in 2009. His laboratory is broadly interested in the molecular pathways that shape nervous system development and function, with the ultimate goal of understanding how dysfunction in these pathways contributes to disease. The current focus is on autism spectrum disorders (ASD), using genetic information from human patients to guide in vitro and in vivo experiments employing biochemical, genetic manipulation, cell biological, and microscopy techniques. Dr. Yi's research has significant clinical implications, particularly in understanding how UBE3A dysfunction relates to both Angelman syndrome (caused by lack of UBE3A activity) and autism (caused by excessive UBE3A activity). His lab discovered that a single phosphorylation event in UBE3A turns off its ubiquitin ligase activity, and that mutations in this site are linked to autism. This work bridges disease genetics with a mechanistic understanding of ASD neurobiology and aims to define developmental timepoints for ASD onset. Dr. Yi's research has been recognized with numerous prestigious awards: Ruth K. Broad Biomedical Research Foundation Predoctoral Fellowship (2006) F32 Kirschstein National Research Service Award (2011) Christina Castellana Postdoctoral Fellowship (2011-2014) The University of North Carolina Postdoctoral Award for Research Excellence (2015) Bridge to Independence Award, The Simons Foundation (2017) NARSAD Young Investigator Award, Brain and Behavior Research Foundation (2018) Whitehall Foundation Research Grant (2018) Alfred P. Sloan Foundation Research Fellowship (2019) Dr. Yi's research program is supported by significant grant funding from organizations including The Simons Foundation, Brain and Behavior Research Foundation, and the Whitehall Foundation. His work bridges basic molecular neuroscience with clinical implications for neurodevelopmental disorders, particularly autism spectrum disorders. Through his research, Dr. Yi is contributing to a deeper understanding of the molecular mechanisms underlying ASD, which may ultimately lead to new therapeutic approaches and interventions. The Yi Lab maintains a collaborative research environment focused on cutting-edge neuroscience techniques. The lab combines molecular, cellular, and genetic approaches to study UBE3A function and its role in neurodevelopment. Their work utilizes patient-derived genetic information to guide experimental approaches, ensuring clinical relevance to autism spectrum disorders. Dr. Yi is also actively involved in mentoring graduate students and postdoctoral fellows, contributing to the training of the next generation of neuroscientists.

Owen Skinnerمشاهده پروفایل

استادیار

• Mass Spectrometry
• Proteomics
• Metabolomics
• +۶ مورد دیگر

Owen Skinner is an Assistant Professor in the Department of Chemistry and Chemical Biology at Northeastern University, affiliated with the Barnett Institute of Chemical and Biological Analysis. He leads the Skinner Lab, which specializes in high-resolution mass spectrometry to study protein-metabolite interactions in health and disease. Skinner earned his Ph.D. from Northwestern University and conducted postdoctoral research at Massachusetts General Hospital. His research focuses on thiol redox regulation, vitamin cofactor metabolism, and oxidative phosphorylation dynamics. Education: Ph.D. in Chemistry (Northwestern University), Postdoctoral Fellowship in Analytical Chemistry (Massachusetts General Hospital). Research interests include proteomics, metabolomics, mitochondrial dysfunction, and metabolic signaling. The lab actively recruits graduate students, undergraduates, and postdoctoral researchers across Northeastern's scientific community. Affiliations: Barnett Institute, College of Science Lab Members: PhD students Yifan Liu, Michael Xiao, Angela Rojas-Merchan; Undergraduates Helena Rittenhouse, Ridha Shah; High School collaborator Helen Loango Techniques: Native mass spectrometry, proteomics, metabolomics, redox biology Publications span mitochondrial metabolism, metabolic biomarkers in septic shock, and enzyme engineering. The lab emphasizes interdisciplinary collaboration and supports students through Northeastern's experiential learning programs.

Karl Peter Gieseمشاهده پروفایل

استاد

• Neurobiology of Mental Health
• Alzheimer's Disease
• Synaptic Plasticity
• +۶ مورد دیگر

Professor Karl Peter Giese holds the position of Professor of Neurobiology of Mental Health and Co-Head of the Basic & Clinical Neuroscience Department at King's College London's Institute of Psychiatry, Psychology & Neuroscience (IoPPN). His research focuses on memory mechanisms in health and disease, particularly Alzheimer's pathology, synaptic dysfunction, and aging effects. He leads projects funded by Alzheimer's Research UK and other institutions, investigating molecular and cellular bases of memory storage. His work bridges experimental models (e.g., mice) with translational insights for clinical applications. He has over 140 publications, including high-impact studies on CYFIP proteins in dementia and CaMKII in synaptic plasticity. Collaborations include researchers at King's College London and international partners. His lab explores mechanisms linking amyloid-beta, tau, and synaptic proteins to cognitive decline, with recent work applying computational methods to model aging brains. Education: PhD from ETH Zurich (1992), MSc Chemistry from Ruhr-University Bochum (1989). Current grants include Alzheimer's Research UK Network Centres and studies on MNK inhibition for Alzheimer's therapies. Projects span protein synthesis dysregulation, thalamic amyloid pathology, and intellectual disability genetics. His research has been featured in Nature Neuroscience , Brain , and Neuron . He advises on translational neuroscience initiatives and mentors early-career researchers.

David Walkerمشاهده پروفایل

استاد

• Aging
• Mitochondrial Biology
• Neurodegeneration
• +۳ مورد دیگر

David Walker is a Professor and Vice Chair of Academic Personnel in the Department of Integrative Biology and Physiology at the University of California, Los Angeles. He leads a research lab focused on understanding the molecular and cellular basis of aging, utilizing Drosophila melanogaster to investigate mechanisms such as mitochondrial dysfunction, autophagy, and intestinal barrier integrity. His work aims to identify therapeutic targets for age-related diseases. Education: B.S., Genetics, Queen's University Belfast (1995) MRes, Molecular Biology, University of Manchester (1996) Ph.D., Genetics, University of Manchester (2000) Walker's research interests center on the biological processes driving aging, with emphasis on mitochondrial dynamics, neurodegeneration, and gut-microbiota interactions. His lab employs genetic, molecular, and physiological approaches in Drosophila to dissect how cellular deterioration impacts lifespan and healthspan, bridging insights to human aging pathologies. Key themes include the role of autophagy adaptors (e.g., p62/SQSTM1), mitochondrial fission, and intestinal homeostasis in longevity. His recent publications (2014–2024) reveal a consistent focus on brain aging, mitophagy, and gut-brain axis disruptions, with trends toward identifying midlife interventions for healthspan extension. Articles frequently integrate cellular stress responses, metabolic regulation, and neurodegeneration, highlighting Drosophila as a versatile model for translational aging research. No scientific awards, prizes, or fellowships are mentioned in the provided text. While specific grants or student advisees are not detailed, Walker's lab actively mentors researchers and contributes to collaborative projects on aging mechanisms. Future directions may involve exploring mitochondrial-immune interactions and novel longevity pathways. Walker directs a Drosophila-focused laboratory at UCLA, emphasizing genetic screens and mechanistic studies to uncover evolutionarily conserved aging pathways. The team investigates tissue-specific aging cascades, including neuronal and intestinal systems, to develop strategies for mitigating age-related decline.

Sophie Caronمشاهده پروفایل

دانشیار

• Neuroscience
• Neurobiology
• Sensory Systems
• +۵ مورد دیگر

Sophie Caron is an Associate Professor in the Department of Biological Sciences at the University of Utah, where she leads a research laboratory investigating fundamental mechanisms of brain function using Drosophila melanogaster as a model system. Her work focuses on how the brain generates internal representations of the external world, stores memories, and translates these into behavior through multisensory integration. Education: B.S. from Université de Montréal Ph.D. from New York University Dr. Caron's research centers on the Drosophila mushroom body—a critical brain center for learning and memory—with emphasis on multisensory integration mechanisms. Her lab investigates how the brain combines information from multiple sensory modalities (olfaction, vision, etc.) to form unified percepts, challenging traditional views of sensory processing. Key discoveries include the demonstration that mushroom body connectivity follows near-random patterns that maximize memory capacity, and the identification of cross-modal sensory pathways beyond olfaction. Current work explores evolutionary adaptations in neural circuits across Drosophila species and developmental mechanisms establishing sensory wiring. Analysis of her 15 most recent publications (2019-2024) reveals three dominant research trajectories: (1) high-resolution mapping of Kenyon cell inputs using advanced techniques like dye electroporation, (2) computational modeling of how connectivity patterns shape sensory representation and learning, and (3) evolutionary studies of circuit architecture across Drosophila species. Her work consistently bridges experimental neuroanatomy with theoretical frameworks, emphasizing the interplay between random and structured wiring principles in neural circuit design. Scientific Awards: NSF CAREER Award (2021) for research on brain size evolution and neuronal circuit adaptation Dr. Caron mentors graduate students in the University of Utah's Molecular Biology Program and directs an active laboratory utilizing genetic, imaging, and behavioral approaches. Her research program is supported by competitive grants including the NSF CAREER award, with collaborations spanning neuroscience and evolutionary biology. Current projects investigate multisensory integration mechanisms, evolutionary drivers of neural circuit specialization, and developmental basis of sensory wiring. The Caron Lab maintains specialized facilities for Drosophila neurogenetics, advanced microscopy, and behavioral analysis. Her team collaborates with the University of Utah's Brain Institute and Center for Cell and Genome Science, contributing to interdisciplinary initiatives in neural circuit mapping and evolutionary neuroscience. Ongoing work explores how sensory representations evolve in response to ecological pressures and how circuit architecture enables flexible behavior in complex environments.

Brendan E. Depueمشاهده پروفایل

دانشیار

• Cognitive Neuroscience
• Neuroimaging
• Emotional Memory
• +۳ مورد دیگر

Brendan E. Depue, Ph.D., is an Associate Professor and Endowed Chair of Behavioral Brain Imaging and Neurobiology in the Department of Psychological and Brain Sciences at the University of Louisville. He also serves as an Affiliate Assistant Professor in the Department of Anatomical Sciences and Neurobiology. His research focuses on the neuroanatomical substrates of inhibitory and cognitive control, particularly within the prefrontal cortex (PFC), using neuroimaging techniques such as fMRI and structural MRI. Depue’s work explores emotional memory regulation, PTSD, anxiety, and decision-making processes. Depue earned his Ph.D. in 2009 from the University of Colorado at Boulder. His lab, the (N)euro(I)maging (L)aboratory of (C)ognitive, (A)ffective and (M)otoric Processes (NILCAMP), investigates how brain networks regulate cognitive, emotional, and motor functions. His research has identified key neural correlates of memory suppression in PTSD, structural covariance differences in depression, and gender-specific neural connectivity during emotion regulation. Recent publications highlight his exploration of fear learning mechanisms, neural networks underlying interoceptive awareness, and the translational potential of the bed nucleus of the stria terminalis in anxiety research. Depue’s interdisciplinary approach integrates clinical neuroscience with advanced imaging methodologies to address complex mental health challenges.

• Neurochemistry
• Alzheimer's Disease
• Biomarker Research
• +۳ مورد دیگر

Javier Saez Valero is a Professor in the Department of Biochemistry and Molecular Biology at Miguel Hernandez University of Elche, where he also serves as Deputy Vice Rector for Research - Management of Research and Transfer. His academic roles include teaching Biochemistry I in the Bachelor's in Medicine program and courses in the Master's in Neuroscience and Master's in Translational Neuropsychopharmacology, while coordinating the Doctorate in Neuroscience program. His research focuses on neurochemical mechanisms in neurodegenerative disorders, particularly Alzheimer's disease biomarker discovery in cerebrospinal fluid and blood. Key areas include NMDA receptor dynamics, ACE2 fragments, apolipoprotein E interactions, and reelin signaling pathways. His work bridges molecular biochemistry with clinical neurology to develop diagnostic tools and understand disease pathogenesis. Analysis of his 15 most recent publications (2023-2025) reveals a dominant focus on Alzheimer's disease biomarkers, especially CSF protein alterations (nicastrin, ADAM10, ACE2). Significant themes include synaptic vs extrasynaptic receptor distributions, COVID-19 neurological impacts, and nanocarrier drug delivery limitations. His work consistently targets translational applications for early diagnosis and therapeutic development. No scientific awards were documented in the provided information. Professor Saez Valero provides academic guidance through tutorials and course coordination across undergraduate, master's, and doctoral programs. As Doctorate in Neuroscience coordinator, he oversees research training while managing institutional research transfer activities through the Vice Rectorate. His teaching spans biochemistry, neuropathology, and molecular neuroscience with laboratory components. He operates from Laboratory 241 at the Institute of Neurosciences (Campus de San Juan), a joint research center with CSIC. His work integrates with the university's Vice Rectorate for Research and Transfer, facilitating technology transfer and collaborative neuroscience research within the university's research infrastructure.

• Gene Therapy
• Paediatric Immunology
• Immunology
• +۴ مورد دیگر

Claire Booth is Professor of Gene Therapy and Paediatric Immunology within the Infection, Immunity & Inflammation Department at University College London. Her work bridges cutting-edge gene therapy techniques with clinical applications for pediatric immunodeficiency disorders, focusing on translating laboratory discoveries into therapeutic interventions for rare genetic conditions. Education: Doctor of Philosophy, University College London (2012) Master of Science, University College London (2007) Bachelor of Medicine/Bachelor of Surgery, King's College London (2001) Professor Booth's research centers on gene therapy approaches for inborn errors of immunity, with particular expertise in lentiviral vector systems, hematopoietic stem cell gene therapy, and genome editing techniques. Her work addresses critical challenges in treating rare immunodeficiency disorders including X-linked SCID, Fanconi anemia, leukocyte adhesion deficiency, and CTLA4 insufficiency. She investigates both the mechanistic underpinnings of these disorders and the development of novel therapeutic strategies that can be translated to clinical practice. Analysis of her recent publications (2023-2024) reveals a strong focus on clinical translation of gene therapy approaches, with numerous phase 1/2 clinical trial results, methodological improvements in conditioning regimens, and exploration of novel targets for immunodeficiency disorders. Her work spans basic science investigations through to clinical implementation, with particular attention to safety profiles, immune reconstitution patterns, and long-term outcomes in pediatric patients. Professor Booth actively collaborates with international research groups and clinical networks, contributing to consensus guidelines for managing rare immunological conditions. Her research program addresses critical gaps in understanding how to effectively deliver gene therapies for rare diseases while navigating the complex challenges of commercialization and accessibility.

• HIV Research
• Antiretroviral Therapy
• Dermatology
• +۴ مورد دیگر

Dr. Jan Nouwen is a faculty researcher at Erasmus MC in the Department of Internal Medicine and Medical Microbiology & Infectious Diseases. His work focuses on HIV-related dermatological alterations, antiretroviral therapy optimization, and microbiome-immune system interactions. Key Research Areas: HIV pathogenesis, antiretroviral drug effects, skin barrier dysfunction, and microbiome changes in immune disorders. Notable Collaborations: ATHENA Observational HIV Cohort, multicohort RESPOND studies. Recent publications highlight his contributions to HIV mortality trends, latency reversal agents, and the role of butyrate in autoimmune conditions like systemic lupus erythematosus. His 2025 review in International Journal of Molecular Sciences synthesizes HIV-associated skin microbiome changes. Scientific Recognition: Recipient of the ICAAC Award (2004) for professional contributions. Methodology: Utilizes prospective cohort studies, clinical trials, and molecular biology approaches.

John S. Kaddisمشاهده پروفایل

دانشیار

• Type 1 Diabetes
• Systems Biology
• Bioinformatics
• +۵ مورد دیگر

John S. Kaddis, Ph.D. is an Associate Professor in the Department of Diabetes & Cancer Discovery Science within the Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope. With over 15 years of experience at City of Hope, Dr. Kaddis has developed scientific resources for team-based research initiatives focused on type 1 diabetes, creating data systems, analysis tools, and websites used by researchers worldwide. Dr. Kaddis earned his B.S. (Honors) in Biochemistry from California State University Los Angeles, where he completed undergraduate research supported by two National Science Foundation fellowships. He later earned his Ph.D. in Systems Biology and Disease from the University of Southern California. His academic journey includes positions as Assistant Professor since 2015 and Associate Professor since 2022 at City of Hope. Dr. Kaddis's research primarily focuses on the complex mechanisms of type 1 diabetes through systems biology and bioinformatics approaches. His work centers on understanding islet cell biology, beta cell dysfunction, and the immunological aspects of type 1 diabetes. His research has evolved from developing collaborative data resources to conducting cutting-edge investigations into genetic factors in diabetes pathogenesis. He has pioneered the creation of bioinformatics platforms that enable global collaboration in diabetes research. The trends in Dr. Kaddis's publications reveal a progression from foundational work on biobanking and data management toward increasingly sophisticated investigations of genetic and immunological mechanisms in type 1 diabetes. His recent work emphasizes translational applications, including potential therapeutic strategies and predictive models that span diverse ancestral backgrounds. His research bridges basic science with clinical applications through the Human Islet Research Network. Member, American Association for the Advancement of Science (2011-Present) Professional Member, American Diabetes Association (2010-Present) Member, Society of Clinical Research Associates (2003-2012) Lifetime Member, Tri-Beta Honor Society (2000-Present) Dr. Kaddis serves as principal investigator and co-investigator on multiple NIH and JDRF-funded projects, including the Human Islet Research Network Bioinformatics Center and the JDRF nPOD DataShare initiative. His work has established critical infrastructure for collaborative diabetes research, enabling researchers worldwide to access and analyze complex datasets. His laboratory has developed specialized data management systems that facilitate the sharing of islet cell research data across international boundaries while maintaining appropriate security and privacy protections. Dr. Kaddis's athletic pursuits in marathons and triathlons mirror his research approach—requiring stamina and perseverance to achieve long-term goals in diabetes research.

Priyanka Baloniمشاهده پروفایل

استادیار

• Systems Biology
• Metabolomics
• Neurodegenerative Diseases
• +۹ مورد دیگر

Priyanka Baloni serves as an Assistant Professor in Purdue University's School of Health Sciences and is a member of the Purdue Institute for Integrative Neuroscience. Her research leverages computational systems biology to investigate metabolic dysregulation in neurodegenerative diseases, cancer, and aging through multi-omics integration. Education: PhD, Indian Institute of Science, 2017 Research Focus: Dr. Baloni specializes in identifying metabolic signatures across neurodegenerative conditions (particularly Alzheimer's disease), preterm birth, and infectious diseases using genome-scale metabolic modeling and network analysis. Her lab develops computational frameworks for multi-omics data (genomics, transcriptomics, metabolomics, proteomics) to study gene-environment interactions, with emphasis on neurotoxic exposures like PFAS. Key contributions include human brain region-specific metabolic networks and identification of bile acids/sphingolipids as Alzheimer's therapeutic targets through NIH AMP-AD collaborations. Publication Trends: Recent work (2023-2025) reveals consistent focus on Alzheimer's mechanisms (APOE interactions, mitochondrial dysfunction), environmental toxicology (PFAS impacts on lipid metabolism), and multi-omics analysis of aging/preterm birth. Her publications frequently emerge from large consortia, demonstrating translational applications of systems biology for biomarker discovery and therapeutic targeting. Scientific Recognition: Laxmi Baxi Award, Society for Reproductive Investigation (2020) CSIR Senior Research Fellowship (2012-2015) UGC Post-Graduate Merit Scholarship (2007-2009) Research Leadership: As Co-Investigator on four NIH grants—including projects on placental development (NICHD R01 HD091527), Alzheimer's target prioritization (NIA U01AG061359), sex differences in AD (NIA RF1AG059093), and microbiome modeling (NIDDK 1R01DK133468)—she directs computational efforts across multi-institutional teams. She actively mentors undergraduate and graduate students in computational toxicology and systems biomedicine. Collaborative Infrastructure: The Baloni Lab develops open-source tools for metabolic network analysis while contributing to Purdue's emerging computational toxicology program. Her work integrates with the Institute for Systems Biology and NIH consortia to address complex health challenges through interdisciplinary data science approaches.