Chromatin Modification Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۶۶۱-۶۷۵ از ۱٬۹۷۱ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Harald Bergerمشاهده پروفایل

پژوهشگر

University of Natural Resources and Life Sciences ViennaAustria

Harald Berger is a researcher at the Institute of Microbial Genetics within the Department of Agricultural Sciences at the University of Natural Resources and Life Sciences, Vienna (BOKU). His work centers on fungal genetics, epigenetics, and secondary metabolism, with a focus on chromatin dynamics and gene regulation in species such as Aspergillus nidulans and Fusarium . He has been actively involved in multiple long-term research projects funded by the Austrian Science Fund (FWF) and regional agencies, primarily as a project staff member under Prof. Joseph Strauss. His research interests include: Fungal epigenetics and chromatin remodeling Regulation of secondary metabolite and mycotoxin production Gene expression dynamics in response to environmental cues Plant-pathogen and microbial interspecies interactions Histone modifications (e.g., H2A.Z, H3K27me3) Berger's recent publications (2020–2025) reveal a strong trend in understanding how chromatin structure governs fungal development and metabolism. His work combines molecular biology, genomics, and systems biology to dissect regulatory networks in filamentous fungi. A recurring theme is the interplay between histone variants and methylation marks in silencing or activating biosynthetic gene clusters. He has contributed to significant findings, including the role of H2A.Z in counteracting H3K27me3-mediated silencing, the function of the KdmB-EcoA-RpdA-SntB chromatin complex, and the identification of signaling molecules like Polaramycin B in microbial crosstalk. ORCID: 0000-0001-7974-3058 Berger has collaborated extensively on projects related to fungal virulence, soil microbial communities, and environmental stress responses. He has also engaged in science communication, notably through the Sparkling Science project "Das Internet der Pilze" (2019). While he does not appear to supervise theses, his collaborative network is broad and impactful. He is based at Konrad Lorenz-Straße 24, 3430 Tulln an der Donau, Austria.

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Aneta Mikulasovaمشاهده پروفایل

پژوهشگر ارشد

University of EdinburghUnited Kingdom

Aneta Mikulasova is a Research Fellow at the University of Edinburgh's Institute of Genetics and Cancer, specializing in (epi)genomic instability in multiple myeloma. Her work investigates large-scale structural variants in heterochromatic regions using advanced genomic technologies and computational methods to understand disease progression and treatment resistance. Her research spans genomic instability, structural variation, chromatin architecture, 3D genome organisation, and epigenomic regulation with direct focus on multiple myeloma, smouldering myeloma, and monoclonal gammopathies. She examines how DNA rearrangements near centromeres disrupt gene regulation in plasma cell disorders, employing multi-omics integration to decode cancer heterogeneity. Analysis of her 2016-2022 publications reveals consistent investigation of genomic landscapes in myeloma progression, structural variant mechanisms like microhomology-mediated end joining, and epigenomic translocations affecting oncogenes. Her work bridges chromatin architecture defects with clinical manifestations in haematological malignancies. Dr. Mikulasova collaborates with NYU Langone Health, University of Miami, Mayo Clinic, and Andalusian Molecular Biology Centre. Her research is funded by the Medical Research Council and charitable initiatives including Peter McCleave & Gob for Good campaign, with major support from DKMS, Love Hope Strength, and Adlard Foundation. She leads a research group utilizing whole-genome sequencing (short/long-read), RNA-seq, ChIP-seq, DNA methylation profiling, and Micro-C 3D mapping to develop computational tools for structural variant detection in plasma cell disorders.

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Manuel Garberمشاهده پروفایل

استاد

University of Massachusetts Chan Medical SchoolUnited States

Manuel Garber, PhD , is a Professor at the University of Massachusetts Chan Medical School , affiliated with multiple departments including Genomics and Computational Biology, Dermatology, and Systems Biology. His research focuses on decoding the functional genome, particularly non-coding RNAs and immune transcriptional regulation, using advanced sequencing technologies. Education : BS in Mathematics, Universidad Simón Bolívar (Venezuela) PhD in Mathematics, Brandeis University (USA) His work integrates computational methods with experimental genomics to map regulatory elements, study lincRNAs , and dissect immune response pathways . Key contributions include developing tools like Scripture and SiPhy for genomic analysis. Recent publications emphasize single-cell RNA sequencing , non-coding RNA evolution , and immune regulatory networks , spanning journals like Nature , Cell , and Science . Collaborations with experimental labs drive discoveries in gene regulation and disease mechanisms.

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Laura Robbinsمشاهده پروفایل

دانشیار

Cornell UniversityUnited States

Laura Robbins, DSW, is an Associate Professor at Weill Cornell Medicine and Senior Vice President of Education Institute & Global Affairs at Hospital for Special Surgery (HSS) . Her work focuses on addressing healthcare disparities through qualitative research and developing public health strategies for disease management in underserved communities. Doctorate in Social Work from Silberman School of Social Work at Hunter College Leadership roles in National Institutes of Health (NIH)-funded studies and NYS Osteoporosis Prevention Program Research Themes : Qualitative methodologies in healthcare access Service utilization for osteoporosis and lupus Knowledge-belief dynamics in patient-centered care Scientific Leadership : Co-investigator on NHLBI-funded Translational Behavioral Research Consortium Principal Investigator for NYSOPEP grant Executive Editor of HSS Journal Advising & Grants : Teaches research courses and mentors academic committees Developed educational frameworks aligned with Accreditation Council on Graduate Medical Education Labs & Collaborations : Collaborates with Weill Cornell Medicine faculty Industry relationships with Arthritis Foundation

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Yael Davidمشاهده پروفایل

دانشیار

Cornell UniversityUnited States

Yael David is an Associate Professor at Memorial Sloan Kettering Cancer Center within the Chemical Biology Program of the Gerstner Sloan Kettering Graduate School of Biomedical Sciences. Her interdisciplinary research bridges chemical biology, biochemistry, and cell biology to investigate epigenetic regulation of transcription in health and disease. Education: B.S. in Biology, Summa Cum Laude, SUNY Stony Brook Ph.D., Weizmann Institute of Science (Biochemistry and Cell Biology) Postdoctoral Training, Princeton University (Chemistry Department with Prof. Tom Muir) Dr. David's research focuses on developing chemical tools to synthesize site-specifically modified histones in vitro and in vivo to study epigenetic mechanisms in disease states, particularly cancer. Her lab pioneered the first synthesis of site-specifically modified histones in animal brains and discovered a new family of histone modifications that alter chromatin structure and function. Current projects investigate non-enzymatic covalent modifications linking metabolism to cell fate, H1 linker histone roles in epigenetic landscapes, novel histone ubiquitination events, epigenetic regulation in HBV infection, and non-canonical chromatin structures in micronuclei. Her work has fundamentally advanced understanding of whether histone modifications causally drive chromatin states or are consequences of transcriptional processes. Analysis of Dr. David's recent publications reveals a strong emphasis on translational epigenetics, with key themes including chromatin-based mechanisms in viral infection (particularly Hepatitis B), metabolic-epigenetic crosstalk through non-enzymatic histone modifications, and chromatin dysregulation in cancer metastasis. Her innovative chemical biology approaches consistently bridge basic mechanistic discoveries with therapeutic applications. Scientific Recognition: NIH/NIGMS Maximizing Investigators' Research Award (MIRA) Pershing Square Sohn Cancer Alliance Award NIH Cutting-Edge Basic Research Award (CEBRA) Chemical Protein Synthesis (CPS) Rising Star in Protein Synthesis Boyer Award in Basic Research Anna Fuller Cancer Research Award Dr. David mentors multiple graduate students and postdoctoral fellows across Weill Cornell Medicine and the Tri-Institutional PhD Program. Her lab has secured substantial funding including an NIH MIRA grant, STARR Cancer Consortium award, and Pershing Square Sohn funding. She actively collaborates with leading researchers including David Lyden, Jackie Bromberg, and Leemore Joshua-Tor on projects spanning cancer metastasis, viral pathogenesis, and structural biochemistry. Dr. David serves as a Josie Robertson Investigator (2016-2021) and organizes international scientific conferences including the Epigenetics & Aging meeting. The David Lab maintains strong collaborative ties with the Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, and the Sloan Kettering Institute. Recent lab expansions include new postdoctoral fellows supported by prestigious EMBO and Swiss National Science Foundation fellowships. The lab actively participates in NYC Chromatin Club and organizes career development workshops for trainees covering pharmaceutical industry, consulting, scientific writing, and startup entrepreneurship.

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Michael G. Kharasمشاهده پروفایل

استاد

Cornell UniversityUnited States

Michael G. Kharas is a Professor at Weill Cornell Medicine's Pharmacology Graduate Program and an Investigator at Memorial Sloan-Kettering Cancer Center's Molecular Pharmacology Program. His research focuses on RNA regulators in hematopoietic stem cells and leukemia pathogenesis, particularly Musashi-2 and m6A methylation mechanisms. Dr. Kharas investigates how post-transcriptional RNA regulation affects symmetric/asymmetric cell division balance in HSCs and leukemic stem cells. His lab develops small molecules targeting RNA-binding proteins and studies metabolic adaptations in leukemia, including fructose utilization and serine synthesis pathways. Current projects explore RNA methylation, chromatin regulation, and screening approaches for self-renewal modulation. His publications reveal trends in RNA biology, epigenetics, and leukemic stem cell targeting. Key subfields include m6A-dependent differentiation control, Musashi-2 networks, metabolic dependencies, chromatin maintenance, and therapeutic strategies against RNA regulators. Leukemia and Lymphoma Society Career Development Award Alex Lemonade Stand Foundation ‘A’ Award American Society of Hematology Junior Faculty Scholar Award Kimmel and V-Scholar Awards Louis V. Gerstner Young Investigator Award As lab head, he mentors researchers and collaborates across institutions. His work spans basic HSC biology, translational leukemia models, and drug discovery platforms targeting RNA-protein interactions.

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Jennifer A. Armstrongمشاهده پروفایل

استاد

Claremont McKenna CollegeUnited States

Jennifer A. Armstrong is Associate Dean of Faculty at Scripps College and Professor of Biology at the Keck Science Department, which is part of the Claremont Colleges consortium in California. She maintains an active research laboratory focused on chromatin and chromosome structure and gene regulation. Dr. Armstrong received her educational training at prestigious institutions: Postdoctoral training at University of California, Santa Cruz Ph.D. from University of California, San Diego B.S. from New Mexico State University Dr. Armstrong's research focuses on chromatin and chromosome structure and gene regulation , with particular emphasis on chromatin remodeling factors that utilize ATP to slide, remodel, or assemble nucleosomes. Her laboratory investigates how these proteins function normally and how their loss can lead to misregulation of the genome and diseases including cancer. She teaches a range of courses including Genetics, Cell Biology, Introductory Biology, Molecular Biology Seminar/Laboratory, and Epigenetics, as well as interdisciplinary courses like Scripps Core I: Histories of the Present: Human Nature and Human Difference and Core II: Constructions of (Dis)Ability. Analysis of Dr. Armstrong's publication record reveals a consistent focus on chromatin remodeling and its role in gene regulation across multiple model organisms, primarily Drosophila melanogaster (fruit fly) and yeast. Her work spans fundamental mechanisms of how chromatin remodelers like CHD1, ISWI, and BRM complexes function at the molecular level, to their roles in development and disease. A recurring theme is how these proteins affect higher-order chromosome structure, histone dynamics, and transcriptional regulation. Her research shows increasing sophistication in methodology, moving from genetic screens to detailed molecular analyses of chromatin structure. Dr. Armstrong serves as Associate Dean of Faculty at Scripps College, indicating significant administrative responsibilities in addition to her research and teaching duties. While specific grant information isn't provided in the available text, her sustained publication record suggests successful funding for her research program over many years. She appears to mentor students through thesis research, as indicated by her listing of "Thesis Topics" related to her laboratory's focus. Dr. Armstrong maintains an active laboratory studying chromatin remodeling factors and their role in genome regulation. Her work bridges molecular, cellular, and developmental biology, using Drosophila and other model systems to understand fundamental mechanisms of chromatin organization and its impact on gene expression.

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Xiao Z.مشاهده پروفایل

پژوهشگر

German Cancer Research CenterGermany

Xiao Z. is a research scientist at the German Cancer Research Center (DKFZ) in Heidelberg, Germany, affiliated with the National Center for Tumor Diseases. Their research focuses on molecular oncology, particularly in the areas of cancer genomics, bioinformatics, and immunotherapy. Xiao Z.'s research interests span multiple cancer types with emphasis on soft tissue sarcomas and medulloblastoma. Their work integrates bioinformatics analysis with experimental validation to identify prognostic biomarkers and understand epigenetic mechanisms driving cancer progression. Recent publications demonstrate expertise in tumor immunology , chromatin modification abnormalities , and CRISPR screening data analysis . Their publication record shows a strong focus on identifying therapeutic targets and understanding resistance mechanisms, particularly in immunotherapy contexts. The research trajectory indicates increasing specialization in molecular mechanisms of cancer progression with translational applications. Xiao Z. has contributed to multiple high-impact publications in journals including Cell Reports , npj Precision Oncology , and Developmental Cell , demonstrating collaborative research across international teams.

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Na Liمشاهده پروفایل

استاد

Baylor College of MedicineUnited States

Na Li is a Professor at the Department of Molecular Physiology and Biophysics , Baylor College of Medicine, with secondary appointments in Medicine and the Cardiovascular Research Institute. Her lab investigates mechanistic links between inflammation, obesity, hypertension, and cardiac arrhythmias , focusing on NLRP3 inflammasome signaling and FKBP5 regulation in atrial fibrillation. Employing multidisciplinary approaches (electrophysiology, transcriptomics, mouse models) Funded by NIH grants and American Heart Association fellowships Research highlights include: Identifying NLRP3 inflammasome as a key driver of atrial fibrillation through calcium dysregulation Developing AAV9 gene delivery systems for atrial-specific modulation Elucidating RyR2 channelopathies in arrhythmia progression Scientific contributions recognized through: Multiple peer-reviewed publications (Circulation, Circulation Research) Collaborative studies with leading cardiovascular researchers NIH R01 and R56 grant awards

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Sandra Cardonaمشاهده پروفایل

استادیار

University of Texas at San AntonioUnited States

Sandra Cardona, Ph.D., is an Assistant Professor of Research in the Department of Molecular Microbiology and Immunology at the University of Texas at San Antonio (UTSA), within the College of Sciences. She serves as the Director of the Cell Analysis Core, a state-of-the-art research facility supporting advanced flow cytometry and confocal microscopy applications. Her research focuses on the role of glial cells in neuroinflammation and neurodegeneration, particularly in diseases such as multiple sclerosis and diabetic retinopathy. Utilizing sophisticated imaging and cytometric techniques, her work investigates microglial activation, fractalkine signaling, and neurovascular dysfunction in mouse models of neurological and metabolic disorders. Dr. Cardona's recent publications reflect a strong emphasis on neuroimmunology, with key contributions to understanding how immune signaling pathways influence central nervous system pathology. Her work integrates cellular neuroscience with immunological mechanisms, particularly in the context of chronic inflammatory conditions affecting the brain and retina. As Director of the Cell Analysis Core, she plays a critical role in training researchers and promoting advanced cytomics across the UTSA research community. She supports a wide range of research projects through access to technologies like the FACS Aria-II, LSR-II, ImageStream-MKII, and Zeiss 710 NLO 2P systems.

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Alexey A. Soshnevمشاهده پروفایل

استادیار

University of Texas at San AntonioUnited States

Alexey A. Soshnev, M.D., Ph.D., is an Assistant Professor in the Department of Neuroscience, Developmental and Regenerative Biology at The University of Texas at San Antonio (UTSA) within the College of Sciences. His research focuses on chromatin structure, gene regulation, and histone biology in development and disease. He leads an active lab investigating epigenetic mechanisms using biochemical, genomic, and imaging approaches. His research interests include: Chromatin structure and function Gene regulation in development and disease Histone biology and biochemistry Epigenetic regulation in stem cells and cancer Linker histone dynamics Transcriptional misregulation The lab's recent publications and ongoing projects span epigenetics, developmental biology, cancer biology, and metabolism. Using tools like proximity labeling, single-molecule imaging, and functional genomics, the team explores how chromatin organization influences cell identity and disease. Their work has implications for understanding cancer, neurodegeneration, and developmental disorders. Award highlights from trainees include: Best poster award at PSU Summer Symposium (Cameron) Departmental research award (Amina) Poster awards at NDRB retreat (Leo, Ashley) Acceptance into prestigious graduate programs (Cameron to Rockefeller University, Gauri to UT Southwestern) Dr. Soshnev has secured external funding from the Cancer Prevention and Research Institute of Texas (CPRIT) and the American Cancer Society. His lab mentors numerous undergraduate and graduate students, including Amina Jumamyradova, Cameron, Dustin Fetch, Gauri Raje, and others. He collaborates with researchers at UT Health San Antonio and beyond, including Dr. Mingjiang Xu. The lab is also involved in multiple national conferences such as ASBMB, NCUR, and DiscoverBMB. Current lab initiatives include: Studying H1 histone loss in B-cell malignancies Developing in vivo single-molecule imaging platforms Investigating lipid-metabolism-epigenetics crosstalk Exploring transcription factor occupancy using biotinylation tagging

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Neil L. Kelleherمشاهده پروفایل

استاد

Northwestern UniversityUnited States

Neil L. Kelleher is the Walter and Mary E. Glass Professor of Molecular Biosciences at Weinberg College of Arts and Sciences and Professor of Medicine (Hematology & Oncology) at Feinberg School of Medicine, Northwestern University. He also serves as Director of the Chemistry of Life Processes Institute and Northwestern Proteomics . His research focuses on top-down proteomics , chromatin biology , and natural product discovery . He leads the global Human Proteoform Project (HPfP) to map 250,000 human proteoforms across 4,000 cell types. His lab developed the ProSight software suite , used by over 1,000 labs worldwide. His publications span computational proteomics, cancer epigenetics, and mass spectrometry applications. Recent articles address automated top-down proteomics , histone methylation dynamics , and non-ribosomal peptide synthesis in Molecular Biosystems , Journal of Biological Chemistry , and Chemistry & Biology . Biemann Medal (2009) Pittsburgh Conference Achievement Award (2008) Pfizer Award in Enzyme Chemistry (2006) Presidential Early Career Award for Scientists and Engineers (2005) Kelleher has mentored ~50 Ph.D. students and postdocs. He co-founded startups like Nativetdms.org and IntegratedProteinTechnologies.com . His lab combines Fourier-Transform Mass Spectrometry with intact protein analysis to study proteoforms and their role in disease.

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Staffan Svärdمشاهده پروفایل

استاد

Uppsala UniversitySweden

Staffan Svärd is a Professor at the Department of Cell and Molecular Biology, Uppsala University, specializing in Microbiology and Immunology. His research focuses on the molecular mechanisms of parasitic protozoa, particularly Giardia intestinalis and related diplomonads. Investigates host-pathogen interactions at cellular and molecular levels Develops genomic and proteomic tools for studying parasite biology Explores drug resistance mechanisms in intestinal parasites His work bridges evolutionary biology and clinical parasitology, with significant contributions to understanding anaerobic eukaryotic cell biology and parasite virulence factors.

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Wilbert T. Zwartمشاهده پروفایل

استاد

Eindhoven University of TechnologyNetherlands

Wilbert T. Zwart is a Professor in the Department of Biomedical Engineering at Eindhoven University of Technology and affiliated with the Netherlands Cancer Institute. His research focuses on epigenetics , prostate cancer , breast cancer , and chromatin dynamics . Expertise Areas : Androgen Receptor, FOXA1, Transcription Factors, Enhancer Regions, Epigenetic Drugs, CRISPR-Cas9 Recent Research Trends : Studied 3D-genome alterations in endometrial cancer, spatial growth constraints in prostate tumors, chromatin drug responses, and estrogen receptor profiling in breast cancer. Collaborations : Netherlands Cancer Institute, Figshare datasets with international teams, and multidisciplinary projects in oncology and systems biology. Media Engagement : Frequently contributes expert commentary on prostate cancer mechanisms, treatment resistance, and computational modeling in oncology.

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Gavin Kelseyمشاهده پروفایل

استاد

University of CambridgeUnited Kingdom

Dr. Gavin Kelsey leads the Epigenetics Programme at Cambridge Reproduction , focusing on how maternal epigenetic inheritance impacts offspring health. His work explores DNA methylation dynamics in oocytes, environmental influences on epigenetic reprogramming, and mechanisms of genomic imprinting. University of Cambridge Cambridge Reproduction network member Centre for Trophoblast Research affiliation Research spans epigenetic reprogramming during gametogenesis, single-cell profiling of oocyte methylation, and maternal physiological impacts on embryo development. Key areas include: DNA methylation establishment in non-dividing oocytes Leptin signaling in ovarian dysfunction Species-specific imprinting mechanisms Transgenerational epigenetic inheritance Epigenetic biomarkers for reproductive outcomes Pioneering single-cell epigenomic techniques to study preimplantation development, with applications in assisted reproductive technologies and obesity-related infertility . Collaborative work extends to common variable immunodeficiency and neurodegenerative epigenetics .

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