جست‌وجوی استاد و پژوهشگر

Katia Sol-Churchمشاهده پروفایل

استاد پژوهشی

• Genomics
• RASopathies
• Cancer Predisposition Syndromes
• +۳ مورد دیگر

Katia Sol-Church is a Research Professor of Pathology at the University of Virginia School of Medicine and serves as the Director of the Genome Analysis & Technology Core within the Office of Research Core Administration. Her academic journey began with a Doctoral Degree in Cellular Biology from Université Paul Sabatier (Toulouse, France) and a Ph.D. in Biomedical Sciences from McGill University (Montreal, Canada). Her research spans genomics , RASopathies , and cancer predisposition syndromes , with a focus on applying omics technologies to enhance biomedical research rigor and reproducibility. She has pioneered discoveries in rare genetic disorders like Costello syndrome and Noonan syndrome, often collaborating with institutions such as Nemours and the University of Virginia. Her publication record reveals a trend toward integrating genomic analysis with clinical applications , including studies on coronary artery disease regulatory mechanisms (2022), auditory neuropathy genetics (2021), and RASopathy phenotyping (2017-2019). Collaborations with teams at UVA, Nemours, and international institutions underscore her interdisciplinary approach. As Director of the UVA Genomics Core, she leads initiatives to advance biomedical research infrastructure , emphasizing scientific reproducibility and clinical genomics across departments like Pathology and Pediatrics.

Karl Forchhammerمشاهده پروفایل

استاد

• Nitrogen regulation in bacteria
• PII signal transduction proteins
• Cyanobacterial metabolism
• +۵ مورد دیگر

Karl Forchhammer is a full Professor at the University of Tübingen , chairing the Department of Microbiology/Organismic Interactions within the Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT) . He received his education at Ludwig-Maximilians-Universität München, earning a Doctorate in Microbiology with a thesis on selenocysteine biosynthesis in Escherichia coli , for which he received the VAAM Promotionspreis in 1992. His academic career includes a postdoctoral fellowship at the Institut Pasteur and associate professorship at the Justus-Liebig-Universität Giessen (1999-2007). Current Roles: Chair of Microbiology/Organismic Interactions, University of Tübingen Editor for FEBS Journal Scientific Advisory Board member, Max Planck Institute for Terrestrial Microbiology DFG panel member (Microbiology, Virology, Immunology) His research focuses on: PII Signal Transduction Proteins : Molecular mechanisms of 2-oxoglutarate sensing, ATP/ADP binding dynamics, and regulatory roles in carbon-nitrogen balance across bacteria, archaea, and chloroplasts. Nitrogen Starvation Response : Molecular basis of chlorosis in Synechocystis and Synechococcus species, including nblA gene regulation and sodium bioenergetics during dormancy. Metabolic Engineering Applications : Development of FRET sensors for metabolite detection and optimization of polyhydroxybutyrate (PHB) production in cyanobacteria. Carbon Regulation Systems : Structural analysis of SbtB redox-sensitive loops, c-di-AMP signaling in diurnal metabolism, and PirC-mediated phosphoglycerate mutase inhibition. Technological Innovations : Creation of SCAGE method for cyanobacterial transport and development of magnetic bead immunoassays for SARS-CoV-2 detection. Scientific contributions include: Discovery of plant kingdom's first glutamine sensory mechanism through PII evolution Elucidation of PII-NAGK functional conservation over 1.2 billion years Identification of 2-oxoglutarate binding site in PII proteins Demonstration of sodium bioenergetics' critical role in cyanobacterial developmental transitions Development of metabolite FRET sensors for real-time metabolic monitoring Establishment of PHB production platforms without nitrogen starvation His lab has trained 15+ PhD students and 3+ PostDocs, with collaborations spanning microbial biotechnology, structural biology, and environmental systems. Recent publications highlight: 2025 work on natural microbial community-enhanced bioplastic production 2024 structural studies of PII-regulated enzymes 2023-2024 investigations into glycogen metabolism and redox regulation 2022-2023 studies on c-di-AMP signaling and toxin-antitoxin systems

Russell Jonesمشاهده پروفایل

استاد

• Immunometabolism
• Cancer Metabolism
• Tumor Immunology
• +۳ مورد دیگر

Dr. Russell Jones is a Professor and Chair of the Department of Metabolism and Nutritional Programming at Van Andel Research Institute (VAI). His research focuses on cancer metabolism, immunology, and the interplay between cellular metabolism and immune function, with a particular emphasis on understanding how metabolic pathways influence tumor growth and anti-tumor immune responses. Dr. Jones earned his B.Sc. and Ph.D. in Biochemistry and Medical Biophysics from the University of Toronto, followed by postdoctoral training at the University of Pennsylvania. He has held academic positions at McGill University and VARI, where he leads a team investigating immunometabolism and cancer metabolism. His work bridges basic research and clinical translation, aiming to develop novel therapies targeting metabolic vulnerabilities in cancer cells and immune cells. His research interests include tumor immunology, metabolic reprogramming in T cells, and the role of metabolic checkpoints in cancer progression. Notable achievements include discovering mechanisms linking LKB1 mutations to gastrointestinal polyposis and identifying metabolic pathways critical for T cell function in tumor microenvironments. Dr. Jones has been recognized with awards such as the William Dawson Scholar distinction and election to the Royal Society of Canada. He serves on editorial boards of leading journals and actively contributes to clinical trials through collaborations with institutions like VAI-SU2C Epigenetics Dream Team. His laboratory is part of VAI’s Center for Cancer and Cell Biology, emphasizing interdisciplinary approaches to metabolism and nutrition. Current projects explore how metabolic interventions can enhance immunotherapy efficacy and uncover metabolic dependencies in cancer cells.

• Breast Cancer
• Endocrine Therapy Resistance
• Cancer Metastasis
• +۴ مورد دیگر

Professor Leonie Young holds a Professorship in the Department of Surgery at the Royal College of Surgeons in Ireland (RCSI), based at York House in Dublin. Her academic career includes roles as Associate Professor (2011–2018) and Professor (2018–present). Her research focuses on uncovering mechanisms of endocrine therapy resistance in breast cancer, particularly involving Steroid Receptor Coactivator (SRC) proteins and metastasis to the brain. She leads the Endocrine Oncology Research Group, leveraging primary patient-derived cell cultures and clinical datasets to identify predictive markers and therapeutic targets. Research Interests: Prof. Young’s work spans breast cancer biology, endocrine resistance, translational oncology, and targeted therapies for metastatic disease. Her group employs high-throughput methods, molecular modeling, and spatial genomics to study SRC-mediated resistance pathways. Current projects include the GeTTMet initiative addressing brain metastasis through genomic adaptations. Grants & Collaborations: She has secured funding from institutions like Science Foundation Ireland, Breast Cancer Ireland, and the EU. Notable grants include the GeTTMet program (2024–2028) targeting brain metastasis via genomic approaches. Her lab collaborates on projects like the OECI Comprehensive Cancer Centre and AICRIstart precision medicine initiatives. Labs & Teams: Leads the Endocrine Oncology Research Group at RCSI, focusing on translational research to bridge molecular insights with clinical applications. The group investigates nuclear receptor interactions, tumor heterogeneity, and novel therapeutic strategies.

Alea Millsمشاهده پروفایل

استاد

• Cancer Biology
• Aging
• Epigenetics
• +۵ مورد دیگر

Alea Mills is a Professor at Cold Spring Harbor Laboratory, leading the Mills Laboratory and serving as Faculty Head of the Animal Shared Resource within the Cancer Center. She is affiliated with the Cancer Center, the Stanley Institute for Cognitive Genomics, and the Gene Regulation and Inheritance departments. Mills earned her Ph.D. in 1997 from the University of California, Irvine. Her research focuses on the genetic and epigenetic mechanisms underlying cancer, aging, and neurodevelopmental disorders like autism. Central to her work is the study of chromatin regulation and its role in diseases such as glioblastoma, squamous cell carcinoma, and senescence. Key projects include investigating the tumor suppressor gene CHD5, the p63 protein family, and chromatin remodeling complexes in cancer progression. Recent publications highlight advancements in glioblastoma treatment through epigenetic reprogramming, the role of ΔNp63α in cancer stemness, and the impact of chromatin modifiers like BRD8 and EZH2. Mills has also contributed to understanding autism using mouse models of 16p11.2 microdeletion. In 2012, she was honored with the 'Woman of the Year in Health/Medicine' award. Her lab collaborates extensively, with a focus on translating basic research into therapeutic strategies. Current efforts include exploring novel targets for cancer and neurodegenerative diseases, alongside investigating the molecular basis of cellular senescence and aging.

Antony Rodriguezمشاهده پروفایل

دانشیار

• MicroRNA Biology
• Lung Disease
• Stem Cell Biology
• +۳ مورد دیگر

Antony Rodriguez, Ph.D., is an Associate Professor at Baylor College of Medicine, affiliated with the Department of Immunology, Allergy & Rheumatology and the Center for Translational Research on Inflammatory Diseases (CTRID). He holds roles as a Graduate Faculty Member in Immunology & Microbiology and Development, Disease Models & Therapeutics. His laboratory focuses on microRNA-mediated mechanisms in lung physiology and repair, particularly in COPD and interstitial lung disease (ILD). Education includes a PhD in Genetics, Development, and Programmed Cell Death from the University of Texas Southwestern Medical Center, followed by a postdoctoral fellowship at the Wellcome Trust Sanger Institute focusing on microRNAs, immunology, and stem cells. Research interests center on microRNA regulation of lung repair, stem cell dysfunction, and inflammation-driven injury. Key projects include let-7 miRNA's role in Tc17 differentiation and fibrogenic pathways. Techniques used include chimeric AGO2-eCLIP, single-cell RNA sequencing (scRNA-seq), and CUT&RUN. Active NIH-funded projects (NHLBI) investigate let-7's role in lung disease pathogenesis and AT2 cell homeostasis. No scientific awards are explicitly listed in the provided text. His work bridges basic science and translational medicine, aiming to develop novel therapies for severe lung diseases such as COPD and ILD.

Karin Sauerمشاهده پروفایل

استاد

• Biofilm Development
• Antimicrobial Resistance
• Microbiology
• +۳ مورد دیگر

Karin Sauer is a Distinguished Professor in the Department of Biological Sciences at Binghamton University. Her research focuses on understanding biofilm formation and resistance in Pseudomonas aeruginosa , with an emphasis on regulatory mechanisms and signaling pathways. She leads the Sauer Lab, part of the Biofilm Group and the Binghamton Biofilm Research Center (BBRC). Dr. Sauer holds a PhD from the Max Planck Institute for Terrestrial Microbiology and MS/BS degrees from Philipps University of Marburg. Her work addresses how biofilms develop antimicrobial resistance, particularly through posttranslational modifications and gene expression changes. Research interests include biofilm dispersion mechanisms, cyclic di-GMP signaling, and the development of strategies to combat biofilm-associated infections. Notable achievements include identifying the role of cis-2-decenoic acid in biofilm dispersion and advancing understanding of biofilm drug tolerance. Dr. Sauer has been recognized as a SUNY Distinguished Professor and a Fellow of the American Academy of Microbiology. Her lab collaborates with other research groups and has trained numerous graduate students and postdoctoral researchers. Key contributions include studies on biofilm matrix dynamics, bacterial communication, and translational approaches to biofilm eradication, such as enzyme-based therapies and surface engineering.

Qianbin Wangمشاهده پروفایل

استادیار

• Mechanotransduction in neuronal systems
• Non-invasive bioinstrumentation for early disease detection
• Gene delivery techniques for ocular applications
• +۳ مورد دیگر

Dr. Qianbin Wang is an Assistant Professor in the Department of Biomedical Engineering at Binghamton University. He holds a Ph.D. in Material Physics and Chemistry from Beihang University (2015) and has conducted postdoctoral research at New York University, Harvard Medical School (Boston Children's Hospital), and the University of Massachusetts Amherst as a Research Assistant Professor. His research focuses on biomechanical platforms to study neural degeneration and regeneration, particularly in glaucoma and spinal cord injury models. Key projects include developing polymeric viscobeads for ocular hypertension studies, non-invasive electroretinography for early glaucoma detection, and ultrasonic gene delivery systems to bypass retinal barriers. Educational Background: Ph.D. in Material Physics and Chemistry, Beihang University (2015) Postdoctoral Training: New York University, Harvard Medical School, UMass Amherst (Research Assistant Professor) Research Interests: Mechanotransduction in neuronal systems Non-invasive bioinstrumentation for early disease detection Gene delivery for ocular applications Neuroinflammation mechanisms in glaucoma Advising & Students: Eunji Hong (non-viral gene delivery) Wenjie (biomedical imaging materials) Ian Kim (glaucoma diagnostics) Chen Lin (hydrogel contact lenses) Labs/Teams: Neuromechanics Lab at Binghamton University, focusing on interdisciplinary approaches to neurodegenerative mechanisms and therapeutic development.

Mariana Raposo Batistaمشاهده پروفایل

استادیار

• Veterinary Sciences
• Embryology
• Cellular Biology
• +۳ مورد دیگر

Mariana Raposo Batista is an Assistant Professor at the Faculty of Veterinary Medicine (FMV-ULHT) of Lusófona University of Humanities and Technologies, where she teaches Anatomy and Reproduction. She holds a Doctorate (PhD) in Veterinary Sciences from the University of Lisbon (FMV-ULisboa, 2020) and has been a veterinarian since 2006. She is also a researcher at the Centro de Investigação Interdisciplinar em Sanidade Animal (CIISA), ULisboa. Her research focuses on mammalian early embryo development, intercellular signaling pathways in cellular differentiation, and embryo-gamete-maternal interactions. She has published peer-reviewed articles and presented at conferences. Recent work includes interdisciplinary studies, such as the CRIAS project, which bridges veterinary medicine, zooarchaeology, and genetics. Her academic contributions include 2 peer-reviewed articles in 2022 and supervision of 4 scholarly works. Collaborations span international and cross-disciplinary networks, emphasizing veterinary education and molecular biology.

• Translational Pharmacology
• Drug Discovery
• Metabolomics/Lipidomics
• +۳ مورد دیگر

Dr. Stan Louie is a Professor of Clinical Pharmacy at the University of Southern California (USC) School of Pharmacy, affiliated with the Ginsburg Institute of Biomedical Therapeutics. His research focuses on translational pharmacology, leveraging metabolomics and lipidomics to identify drug targets for neurodegenerative diseases, inflammation, and regenerative therapies. Dr. Louie has advanced four therapeutic modalities from preclinical stages to clinical evaluation, with a particular emphasis on Alzheimer’s disease, retinal degeneration, and traumatic brain injury (TBI). His academic training and career are rooted in clinical pharmacy, with a strong emphasis on drug discovery and development. Key research interests include the role of bioactive lipids in neuroinflammation, the impact of APOE4 genotype on brain metabolism, and the development of targeted therapies using antibody-drug conjugates and nanoparticle systems. Dr. Louie’s recent work highlights innovations such as transcorneal electrical stimulation for retinal neuroprotection, hydroxypropyl-β-cyclodextrin barriers for antiviral delivery, and omega-3 fatty acid supplementation in TBI patients. His lab also explores the mechanistic links between lipid metabolism, inflammation, and disease progression in conditions like alcoholic hepatitis and liver cancer. His awards include Fellowships from the American and California Societies of Health System Pharmacists (2000 and 1998, respectively), the Rho Chi Honor Society (1985), and a March of Dimes Research Fellowship (1979–1982). His research has been published in high-impact journals such as *Nature Communications*, *ACS Chemical Neuroscience*, and *Molecular Cancer Therapeutics*. Dr. Louie’s translational efforts bridge basic science and clinical application, with a focus on preclinical and early-phase clinical trials. His lab collaborates on projects involving drug delivery systems, biomarker discovery, and the optimization of therapeutic strategies for chronic and acute conditions.

Yao Wei Luمشاهده پروفایل

استادیار

• Cardiovascular Biology
• Cardiovascular Disease
• Molecular Medicine
• +۳ مورد دیگر

Yao Wei Lu is an Assistant Professor of Medicine at the University of Southern California, affiliated with the Hastings Center for Pulmonary Research and leading the Lu Lab. Their research focuses on cardiovascular development, regeneration, and diseases, particularly investigating mechanisms underlying cardiac fibrosis, diabetic complications, and the role of non-coding RNAs in cardiovascular pathologies. Key areas include endothelial dysfunction, metabolic disorders, and molecular signaling pathways in heart disease. Research interests emphasize translational studies targeting therapies for cardiac hypertrophy, atherosclerosis, and heart failure. Dr. Lu's work integrates molecular biology, cell biology, and systems biology approaches to understand disease mechanisms and develop novel treatments. Notable achievements include the receipt of the American Heart Association (AHA) Second Century Early Faculty Independence Award in 2023. The lab's studies often involve collaborative projects on nanotherapies, epigenetic regulation, and cellular senescence. Current projects explore therapeutic inhibition of non-coding RNAs and mitochondrial dysfunction's role in cardiomyocyte regeneration.

• Pulmonary Research
• Lung Development
• Bronchopulmonary Dysplasia
• +۵ مورد دیگر

Parviz Minoo, PhD is a Professor of Pediatrics at the Keck School of Medicine, University of Southern California, where he also serves as Director of the USC Hastings Center for Pulmonary Research. His research focuses on pulmonary development and disease, with particular emphasis on understanding the molecular mechanisms underlying lung morphogenesis and alveolar development. Dr. Minoo's research interests center on pulmonary biology with a focus on lung development, alveologenesis, and bronchopulmonary dysplasia. His work investigates the complex signaling pathways involved in lung formation, including Wnt, FGF, TGF-β, and Hedgehog signaling networks. He has made significant contributions to understanding how transcription factors like NKX21 regulate lung epithelial cell differentiation and how growth factors such as FGF10 drive alveolar formation. His research bridges basic developmental biology with clinical applications for neonatal respiratory disorders. Analysis of Dr. Minoo's recent publications reveals a consistent focus on the molecular mechanisms of alveologenesis and lung regeneration. His work demonstrates how specific signaling pathways (Wnt5a, FGF10, Hedgehog) interact with transcription factors (NKX21, FOXO1) to regulate alveolar cell differentiation. The research spans from fundamental developmental biology to potential therapeutic applications for bronchopulmonary dysplasia and pulmonary fibrosis, with increasing attention to cellular plasticity, progenitor cell niches, and the role of the extracellular matrix in lung development. As Director of the USC Hastings Center for Pulmonary Research, Dr. Minoo oversees a multidisciplinary team investigating lung development, injury, and repair mechanisms. His laboratory employs sophisticated mouse models, organoid cultures, and molecular techniques to unravel the complexities of pulmonary biology. The center serves as a hub for collaborative research connecting basic science with clinical applications in neonatal and pediatric pulmonary medicine.

• Pediatrics
• Regenerative Medicine
• Developmental Biology
• +۵ مورد دیگر

David Warburton, MD is a Professor of Pediatrics at the University of Southern California (USC), affiliated with the Saban Research Institute at Children's Hospital Los Angeles (CHLA). His work bridges neonatal-perinatal medicine, developmental biology, and regenerative medicine, with a focus on lung morphogenesis, repair, and fibrosis. He has pioneered studies on molecular embryology of the lung, including growth factor and extracellular matrix roles in lung development and disease. Warburton's research spans clinical and basic science, including management practices for extreme prematurity, fetal lung maturation, and pediatric interstitial lung diseases. He collaborates internationally, particularly in the UK, and mentors doctoral and postdoctoral fellows. His awards include the Order of the British Empire (2009) for UK/US scientific collaboration and fellowships from Royal Colleges of Surgeons, Physicians, and Paediatrics. Key research areas include environmental health impacts (e.g., air pollution in Mongolia), post-COVID-19 pediatric sequelae, and clinical trials for nintedanib in fibrosing interstitial lung diseases. His studies leverage stem cells, extracellular vesicles, and molecular signaling pathways to advance regenerative therapies. Awards: OBE (2009), Royal College Fellowships Grants: NIH, CIRM, UK MRC/BBSRC Key Projects: LungMAP molecular atlas, Mongolian air pollution cohort studies

Iman Azimiمشاهده پروفایل

مدرس ارشد

• Brain Cancer
• Cellular Aging
• Calcium Signaling Pathways
• +۳ مورد دیگر

Iman Azimi is a Senior Lecturer and Research Group Head in the Pharmacology Department at Monash Biomedicine Discovery Institute, Monash University. His academic journey includes a PhD from the University of New South Wales (2011), postdoctoral research at The University of Queensland (2011–2017), and a Lecturer role at the University of Tasmania (2018–2023). He leads research focused on brain cancer, cellular aging, calcium signaling, and drug discovery. His work is supported by grants from Cancer Council Tasmania, Brain Foundation, and others. Education: PhD in Pharmacology, University of New South Wales, 2011 Postdoctoral Fellowship, The University of Queensland, 2011–2017 Research Interests: Identifying therapeutic targets for brain cancers (e.g., medulloblastoma) Unraveling cellular aging mechanisms Calcium signaling in cancer and senescence High-throughput drug screening assay development Publications: Recent articles focus on LIN28 proteins in medulloblastoma, T-type calcium channel inhibitors, and calcium signaling pathways. His work bridges basic science and translational applications in cancer therapy. Awards: Includes the ASCEPT New Investigator Award (2016), Oxygen Club of California Award (2015), and multiple grants and scholarships. Leadership & Service: Chair of Institutional Biosafety Committees, Guest Editor for Cancers and Frontiers in Pharmacology , and grant reviewer for NHMRC and international agencies. Labs/Teams: Leads a research group at Monash focused on cancer and aging biology, with expertise in cell culture, fluorescence microscopy, and high-content imaging.

Andreas Lundqvistمشاهده پروفایل

استاد

• Cancer and Oncology
• Cell and Molecular Biology
• Immunology in the medical area

Andreas Lundqvist is a Professor at the Department of Oncology-Pathology, Karolinska Institutet. His research focuses on understanding mechanisms of immune escape in solid tumors, particularly investigating NK and T cell regulation. He leads the Cell-based Immune Therapy for Cancer group, aiming to develop novel immunotherapies. Education & Roles: PhD in Immunology, Karolinska Institutet (2003) Professor since 2023; Associate Professor (2012–2023); Assistant Professor (2009–2012) Prior roles include Staff Scientist and Research Fellow at the National Institutes of Health (NIH) (2003–2008) Research Interests: Lundqvist's work targets immune evasion in cancer, with emphasis on NK and T cell dynamics. His group explores tumor microenvironment interactions, immune checkpoint modulation, and biomarker discovery. Recent studies focus on renal cell carcinoma, melanoma, and Hodgkin lymphoma. Grants & Funding: Swedish Childhood Cancer Fund (2024–2025) Swedish Research Council (2023–2026) Swedish Cancer Society (2022–2024) Advising & Labs: Lundqvist supervises a research group including PhD students and postdoctoral fellows. Notable alumni include Dhifaf Sarhan (Karolinska Institutet) and Erik Wennerberg (The Institute of Cancer Research).