جست‌وجوی استاد و پژوهشگر

Peter Burkeمشاهده پروفایل

استاد

• Nanoelectronics
• Quantum Electronics
• Graphene Electronics
• +۷ مورد دیگر

Peter Burke is a Professor of Electrical Engineering and Computer Science (joint appointments in Biomedical Engineering and Materials Science and Engineering ) at the Samueli School of Engineering, University of California, Irvine . His research bridges nanoelectronics with biotechnology , focusing on carbon nanotubes , graphene devices , and mitochondrial bioenergetics . He has received prestigious Young Investigator Awards from the Office of Naval Research and Army Research Office. Education: B.A. in Physics, University of Chicago (1992) Ph.D. in Physics, Yale University (1998) His work spans quantum electronics , high-speed semiconductor devices , and bio-nano interfaces . Recent publications highlight drone technology , mitochondrial electrical activity , and AI-driven nanoscale sensing . Research trends include terahertz spectroscopy , super-resolution imaging , and open-source medical devices like the NanoStat potentiostat . Scientific Awards Young Investigator Award, Office of Naval Research Young Investigator Program Award, Army Research Office As director of the BurkeLab , he develops nano-electronic interfaces for biological systems, including mitochondrial membrane potential assays and graphene-based biosensors . His lab's innovations in carbon nanotube arrays and scanning microwave microscopy have advanced bio-nano applications.

Rui Kangمشاهده پروفایل

دانشیار

• Pancreatic Cancer
• Ferroptosis
• Cancer Biology
• +۴ مورد دیگر

Rui Kang, MD, PhD, is an Associate Professor in the Surgery Department at the University of Texas Southwestern Medical Center. Her research focuses on molecular mechanisms of pancreatic cancer, ferroptosis, and sepsis, with particular attention to tumor microenvironments and immunological pathways. She holds a medical degree and PhD from Chinese institutions (Xiangya School of Medicine and Norman Bethune College of Medicine) and completed postgraduate training at the University of Pittsburgh Cancer Institute. Dr. Kang’s work is supported by the NIH, and she contributes to editorial boards of oncology and gastroenterology journals. Her research interests span pancreatic cancer biology, ferroptosis regulation, and the interplay between cell death mechanisms and immune responses. Notable areas include investigating how platelet activation hinders antitumor immunity, mitochondrial-driven ferroptosis pathways, and the role of glutathione metabolism in cancer therapy resistance. Recent studies explore novel cell death modalities like triaptosis and alkaliptosis, alongside metabolic drivers of disease progression. Dr. Kang has authored dozens of peer-reviewed articles and book chapters, contributing to guidelines on ferroptosis detection and therapeutic strategies. Her work bridges basic science and clinical applications, emphasizing translational research in oncology and immunology.

• Diabetic Nephropathy
• Chronic Kidney Disease
• Maternal and Fetal Health
• +۳ مورد دیگر

Carol Pollock is a Professor at the University of Sydney's Northern Clinical School , affiliated with the Kolling Institute of Medical Research . Her research focuses on diabetic kidney disease, chronic kidney disease (CKD) management, and maternal-fetal programming of renal health. Thematic areas: Obesity, Diabetes, Cardiovascular Disease , Healthy Ageing , and Lifespan Methodological approaches: Animal models , Cellular/molecular studies , and Translational research Clinical specialty: Nephrology Her work explores epigenetic mechanisms in maternal obesity-related kidney disease, SGLT2 inhibitors for cardiorenal protection, and novel biomarkers like urinary exosomes and volatile organic compounds. Recent studies emphasize intergenerational metabolic programming and renoprotective drug development . Key publication trends (2023-2025) include: Diabetic nephropathy (2025: SGLT2 inhibitors, YAP1 pathways) CKD progression (2024: DISCOVER cohort, hyperkalemia management) Maternal environmental impacts (2025: PM2.5 exposure, fetal kidney health) Renal fibrosis (2023: i-body AD-214, CXCR4 blockade) Translational nephrology (2024: urinary cell imaging, exosome therapy) Global CKD guidelines (2024: Asia-specific management frameworks) Her team mentors PhD students Daisy Chen, Wenyang Shi, and Chi Tran, investigating stem cell therapies and renal regeneration in diabetic and acute kidney injury models.

Karl-Heinz Wagnerمشاهده پروفایل

استاد

• Oxidative stress and DNA stability
• Molecular nutrition and phytochemicals
• Dietary antioxidants and aging
• +۵ مورد دیگر

Karl-Heinz Wagner is Full Professor of Nutrition and Food Quality at the University of Vienna, Faculty of Life Sciences, Department of Nutritional Sciences. He directs an experimental research group investigating how lifestyle factors—diet, specific food components, phytochemicals, physical activity and bioactive non-food compounds—modulate oxidative stress and DNA stability in humans, with emphasis on aging and sarcopenia. He initiated the university-wide “Active Ageing” research platform and coordinates EU projects such as SHIFT2HEALTH. Education & Affiliations: University of Vienna, Faculty of Life Sciences, Department of Nutritional Sciences – Professor and Chair of Nutrition and Food Quality Principal investigator of the Emerging Field “Oxidative Stress and DNA Stability” Head of the “Active Ageing” research platform activeageing.univie.ac.at Research Focus: Prof. Wagner’s group applies state-of-the-art biochemical and molecular techniques to quantify antioxidant compounds, ROS-induced DNA and chromosomal damage, DNA repair capacity and transcriptional regulation of antioxidant defenses. Human intervention trials, cross-sectional cohorts and in-vitro models are used to examine: Impact of plant-based vs. animal-based diets on multimorbidity risk Nitrate-rich beetroot juice effects on microbiome, vascular function and oxidative stress Bilirubin biology and metabolic health in Gilbert’s syndrome High-protein nutrition and resistance training on DNA damage and muscle quality in older adults Microbiota-derived metabolites that enhance CD8 T-cell antitumor immunity after exercise Publication Trends 2023-2025: Recent output demonstrates a strategic shift toward multi-omics integration (metabolomics, lipidomics, proteomics) to dissect diet–microbiome–immune crosstalk and to identify predictive biomarkers of healthy ageing. Papers consistently appear in top-tier journals (Cell, Lancet Healthy Longev, Redox Biol, Mol Nutr Food Res) and embrace large multinational cohorts, randomized controlled trials and mechanistic animal/cellular work. Funding & Networks: Research is mainly funded by the Austrian Science Fund (FWF), National Bank, European Commission (Horizon 2020, Horizon Europe), EU Cross-Border Co-operation and the University of Vienna. A dense national and international partner network ensures continuous biomarker development and knowledge transfer. Student Training & Citizen Science: Prof. Wagner actively involves MSc/PhD students and post-docs in externally funded projects and advertises internships via ERASMUS+. Study participant recruitment portals for projects like SHIFT2HEALTH, NUTRIAGING and bilirubin clinical studies are maintained to engage the public and foster translational impact.

• Medicinal Chemistry
• Chemical Biology
• Organic Synthesis
• +۳ مورد دیگر

Wei Shi is an Associate Professor of Chemistry (Organic) at Ball State University’s College of Sciences and Humanities, Department of Chemistry. He joined the institution in 2019, specializing in teaching Organic Chemistry and conducting research in Medicinal Chemistry, Chemical Biology, and Organic Synthesis. His research focuses on designing chemical probes derived from natural products to understand small molecule regulation of macro-biomolecules for disease treatment. Education: B.Sc. in Electrochemistry from Shanghai Jiao Tong University (China), M.Sc. in Bioorganic Chemistry from East China University of Science & Technology (China), Ph.D. in Chemistry from the University of Alberta (Canada), and postdoctoral training at Johns Hopkins School of Medicine (USA). Research Interests: Explores the pharmaceutical potential of bioactive natural products, particularly glycoconjugates, aiming to design novel drug candidates with enhanced therapeutic profiles. Key projects include studying ipomoeassin F’s mechanism of action as an ER translocon inhibitor and developing itraconazole analogs for antiangiogenic and anticancer applications. Selected Publications: Over 20 peer-reviewed articles, including landmark studies on ipomoeassin F’s Sec61α binding, itraconazole’s dual targeting of NPC1/VDAC1, and structural analog design. Recent work highlights Sec61 translocon inhibition mechanisms in Mycobacterium ulcerans pathogenesis and ER stress response modulation in cancer cells. Labs/Teams: Director of the Shi Research Group , focusing on natural product-inspired drug discovery and chemical biology.

Peter Matthiasمشاهده پروفایل

استاد

• Biochemistry
• Cell Biology
• Cell division
• +۷ مورد دیگر

Matthias Peter is a Professor of Biochemistry at ETH Zurich, leading research into mechanisms governing cell growth and division. His laboratory focuses on ubiquitin-dependent regulation of DNA replication and mitosis, and autophagy's role in cellular quality control. He chairs the Department of Biology (2011-2015) and holds leadership roles in Switzerland's research infrastructure, including Vice Chair of ScopeM's microscopy platform. His academic career includes roles at ISREC (1996-2002) and postdoctoral training at UCSF (1991-1996). Education: PhD in Biochemistry from ISREC (1991), ETH Zurich diploma in Gene Technology (1987). Research interests span molecular mechanisms of cell division, ubiquitin systems, and autophagy. Awards include ERC Advanced Grant (2011) and UBS Excellence in Research (2002). Leadership: Member of Swiss National Research Council, SNF selection committee, and SWTR council. Over 20 years of committee service in national research programs. His lab's work is published in top journals like Science, Nature, and Molecular Cell.

Nikolaus Pfannerمشاهده پروفایل

استاد

• Protein Structure and Function
• Targeting, translocation and folding of mitochondrial proteins
• Biogenesis of Mitochondria: Protein Transport and Assembly

Professor Nikolaus Pfanner, a leading figure in mitochondrial biogenesis and protein transport, has held the Chair of Biochemistry and Molecular Biology at the Institute of Biochemistry and Molecular Biology, University of Freiburg, since 1992. His leadership roles include serving as President of the German Society for Biochemistry and Molecular Biology (2009–2011) and Council Member of the University of Freiburg (since 2008). His research focuses on the targeting, translocation, and folding of mitochondrial proteins , biogenesis of mitochondria , and protein structure and function . Key contributions include elucidating the TOM complex’s role in protein import and the SAM complex in β-barrel assembly. Recent publications explore mitochondrial import stress , complexome analysis , and MIMAS mega-assembly . His work integrates structural biology , proteomics , and kinase regulation . Awarded the Leibniz Prize (2004), Stein and Moore Award (2014), and Hector Research Award (2011), Pfanner is a member of EMBO , Leopoldina , and Academia Europaea . He has mentored numerous researchers, including Thomas Becker , Chris Meisinger , and Nils Wiedemann . His lab receives funding from the Deutsche Forschungsgemeinschaft (DFG) and EXZ BIOSS (since 2010).

Ritwick Sawarkarمشاهده پروفایل

عضو هیئت علمی

• Chromatin Biology
• Environmental Stress Response
• Transcriptional Regulation
• +۳ مورد دیگر

Ritwick Sawarkar is a Principal Investigator at the MRC Toxicology Unit and affiliated with the Department of Genetics under the School of Biological Sciences at the University of Cambridge. He leads the Sawarkar Group, focusing on molecular mechanisms linking chromatin biology, environmental stress response, and transcriptional regulation. Education: PhD in Genetics (Indian Institute of Science, 2010) Previous roles: Postdoctoral Fellow at ETH-Zürich (2010-2014), Independent Group Leader at Max Planck Institute (2014-2019) Research Interests : The Sawarkar Group investigates how chromatin interprets environmental stress signals to modulate transcriptional responses. Key questions include: (i) Cellular pathways sensing stress/toxins, (ii) Chromatin's role in stress adaptation, and (iii) Transcriptional mechanisms for cellular survival. Their work integrates genomics, single-cell transcriptomics, proteomics, and mouse models to explore stress response pathways. Article Trends : Recent publications highlight his expertise in chromatin-mediated stress responses, non-coding RNA interactions, and proteostasis networks. Collaborations with pharmaceutical companies emphasize translational applications for drug toxicology and RNA therapeutics. Scientific Awards : ERC Consolidator Grant (2018) Alfred Tissières Young Investigator Award (2019) Group Members : His team includes PhD students (Dimitris Aspri, Roberto Campalastri), Research Associates (Simone Baldan, Christo Christov), and MPhil students (Anfas Muhammed, Keely Xia), among others.

Ruan Elliottمشاهده پروفایل

مدرس ارشد

• Nutritional Metabolism
• DNA Damage and Repair
• Nutrigenomics
• +۴ مورد دیگر

Dr Ruan Elliott is Dean of the Doctoral College and Senior Lecturer in Nutrition at the University of Surrey's School of Biosciences. He holds a PhD in Nutritional Metabolism (2017) and BA in Natural Sciences from Cambridge (1988). His research focuses on nutritional modulation of DNA repair mechanisms, functional genomics in nutrigenomics, and micronutrient homeostasis of iron, copper, selenium, and zinc. He has led studies on vitamin D efficacy, food bioavailability, and oxidative stress biomarkers. Education: PhD (University of Surrey, 1992), BA (University of Cambridge, 1988) Previous Roles: Senior Scientist (Institute of Food Research, 1994-2009), Postdoctoral Fellow (University of British Columbia, 1992-1994) His research integrates molecular biology and nutrition to address health impacts of dietary components. Recent work explores oat-based milk alternatives' sensory profiles, vitamin D supplementation efficacy, and DNA repair pathways in cardiovascular disease. He collaborates internationally on projects like the D2-D3 Study and NuGO initiatives. Publications emphasize translational research, including systematic reviews on insect protein efficacy and meta-analyses of vitamin D supplementation. His work bridges lab-based models (e.g., Caco-2 cells for iron studies) and clinical applications. No scientific awards were explicitly listed in the provided texts. He advises on doctoral training programs and has contributed to grant-funded projects like the University of Surrey's food and infection biosciences initiative (2024). Collaborations include studies on probiotics' immune effects and transcriptomic analysis of metabolic conditions.

Heike Krebberمشاهده پروفایل

استاد

• mRNA Quality Control
• ncRNA Functions
• Molecular Biology
• +۳ مورد دیگر

Prof. Heike Krebber is a Professor for Molecular Genetics at Georg-August University Göttingen, Germany. Her research focuses on mRNA quality control and non-coding RNA functions, using the model organism Saccharomyces cerevisiae. She has held positions at the DKFZ (Heidelberg), Harvard Medical School, and Philipps-Universität Marburg. Her work addresses how mRNA processing defects contribute to diseases like cancer and neurodegeneration. Education & Positions: PhD (1996), Deutsches Krebsforschungszentrum Heisenberg Fellow (2006) Habilitation in Molecular Biology (2005) Professor since 2010 at Georg-August University Research Interests: Her lab investigates: RNA quality control mechanisms ensuring proper mRNA maturation and export Functions of non-coding RNAs (e.g., lncRNAs in iron metabolism and telomerase) Ribosome assembly and translation termination pathways Stress-induced bypass of mRNA quality control Awards: Heisenberg Fellowship (2006) Grants & Teams: Leads the Molecular Genetics group at the Institute for Microbiology and Genetics. Collaborates with the IMPRS Molecular Biology and GZMB (Molecular Biology of Cells) programs. Labs & Affiliations: Her group is part of the GGNB network, focusing on Microbiology and Biochemistry. The lab’s work spans fundamental molecular mechanisms with translational disease relevance.

Anton Baysaمشاهده پروفایل

مدرس ارشد

• Cardiology
• Molecular Biology
• Cardiovascular Pathology
• +۵ مورد دیگر

Anton Baysa is a Senior Lecturer at the University of Oslo's Department of Pathology within the Faculty of Medicine. His research focuses on cardiovascular pathophysiology, particularly mechanisms of inflammation, mitochondrial dysfunction, and cellular repair following myocardial infarction and ischemia-reperfusion injury. He has published extensively on topics including Toll-like receptor signaling, mitochondrial DNA-induced inflammation, and the role of adaptor proteins in cardiac healing. His work integrates molecular biology, immunology, and clinical cardiology to understand and mitigate cardiac damage. Collaborative projects include studies on extracellular vesicles in surgery-related complications and growth factor pathways in myocardial repair. Key Research Themes: Cardiac inflammation mechanisms, mitochondrial damage responses, post-infarction healing, oxidative stress mitigation Recent Projects: Investigating p66ShcA protein signaling, nucleolin inhibition effects, and BMP-mediated cardiac remodeling

Patricia J. Hillerenمشاهده پروفایل

دانشیار

• Molecular Biology
• Biochemistry
• RNA Biology
• +۵ مورد دیگر

Patricia J. Hilleren is an Associate Professor of Biology and current Department Chair at Skidmore College , Saratoga Springs, NY. Her research focuses on nuclear mRNA quality control systems and gene expression accuracy in eukaryotic cells, using Saccharomyces cerevisiae as a model organism. She earned her PhD in Biochemistry, Molecular Biology, and Biophysics from the University of Minnesota (1997) and completed postdoctoral research at the Howard Hughes Medical Institute, University of Arizona (1997-2003). Education: B.S., Microbiology (1987), St. Cloud State University Ph.D., Biochemistry, Molecular Biology, and Biophysics (1997), University of Minnesota Postdoctoral Research (1997-2003), Howard Hughes Medical Institute, University of Arizona Courses Taught: Liberal Sciences I Molecular Cell Biology (BI 242) Chromatin Structure, Maintenance and Function (BI 360) mRNA Synthesis, Processing, and Turnover (BI 363) Research Interests: Hilleren investigates nuclear quality control systems that ensure accurate gene expression, focusing on how defective pre-mRNAs are recognized, retained at transcription sites, and removed in eukaryotic cells. Her work addresses fundamental cellular mechanisms through yeast genetics and molecular biology approaches. Publication Trends: Her research spans RNA biology, gene expression regulation, and mRNA surveillance systems. Key themes include nuclear RNA processing errors, cytoplasmic degradation pathways, and molecular mechanisms of mRNA quality control in Saccharomyces cerevisiae . Contact: Office: Biology Department - CIS 210A Phone: (518) 580-8301 Email: phillere@skidmore.edu Office Hours: Tuesdays 10:30am-12noon, Thursdays 2:15pm-3:30pm

• Radiation Oncology
• Cancer Biology
• Molecular Targeted Therapy
• +۷ مورد دیگر

Joseph N. Contessa, MD, PhD is an Adjunct Professor of Therapeutic Radiology and Pharmacology at Yale School of Medicine, where he serves as Director of Yale Medicine's Central Nervous System Radiotherapy Program. His clinical practice focuses on treating patients with brain tumors, head and neck cancers, and tumors at the base of the skull, including rare entities such as low-grade and malignant gliomas, ependymomas, high-grade meningiomas, hemangiopericytomas, paragangliomas, and schwannomas. Dr. Contessa's research spans multiple areas of cancer biology with a particular emphasis on molecular mechanisms of therapeutic resistance and novel approaches to radiosensitization. His work explores the role of N-linked glycosylation in cancer progression and treatment resistance, developing small molecule inhibitors targeting this pathway to overcome resistance to EGFR tyrosine kinase inhibitors. He also investigates targeted therapies for head and neck squamous cell carcinoma, molecular imaging of the epidermal growth factor receptor, and drug discovery through high-throughput screening approaches. Analysis of Dr. Contessa's recent publications reveals a consistent focus on the intersection of radiation oncology and molecular biology, particularly examining how glycosylation pathways influence cancer cell response to radiation and targeted therapies. His work spans basic science investigations into protein folding and quality control mechanisms to clinical applications in lung cancer, brain tumors, and head and neck cancers. A significant portion of his research explores how inhibiting specific glycosylation enzymes can sensitize tumors to radiation therapy. Dr. Contessa actively collaborates with leading researchers at Yale including Veronica Chiang (6 publications), Barbara Burtness (2 publications), Kimberly Johung (2 publications), and Scott Gettinger (2 publications). He serves as a Sub Investigator on the clinical trial 'Determining Mechanisms of Sensitivity and Resistance to Anti-Cancer Therapy for Advanced Lung Cancer' (HIC ID 1603017333), which is scheduled for primary completion in June 2026. His laboratory work is closely integrated with clinical care through multiple Yale centers including the Brain Tumor Center, Gamma Knife Center, Head and Neck Cancers Program, and Yale Cancer Center. Dr. Contessa's research bridges basic science discoveries in protein glycosylation with clinical applications in radiation oncology, creating a translational pipeline from bench to bedside for patients with challenging malignancies.

Adam Frostمشاهده پروفایل

استادیار

• Electron Cryo-Microscopy
• Structural Biology
• Membrane Biology
• +۳ مورد دیگر

Adam Frost, MD, PhD is an Assistant Professor in the Department of Biochemistry at the University of Utah School of Medicine and a member of the Cell Response and Regulation Program at the Huntsman Cancer Institute. His research employs structural biology approaches to investigate fundamental cellular processes with implications for understanding cancer and other diseases. Education: Postdoctoral Fellowship: University of California, San Francisco MD: Yale University School of Medicine PhD: Yale University BS: Brigham Young University Dr. Frost specializes in the molecular and structural biology of membrane trafficking, with a particular emphasis on mechanisms that determine membrane shape and topology. His laboratory utilizes electron cryo-microscopy to obtain molecular-scale views of cellular machinery as it engages with and reshapes cellular membranes. This work has direct relevance to understanding cancer, as several components of the cell division machinery have been genetically implicated in tumor formation. His research bridges structural biology, membrane biology, and cell division mechanisms, providing critical insights into how cellular membranes are dynamically remodeled during essential biological processes. Analysis of Dr. Frost's publications from 2011-2015 reveals a consistent focus on membrane remodeling proteins and their roles in cellular processes. His work spans multiple model systems and employs diverse structural biology techniques, with a particular emphasis on cryo-EM. The research demonstrates how membrane-binding proteins influence membrane topology during critical cellular events, especially cell division. These studies have provided direct molecular insights into cellular machinery that was previously difficult to visualize, opening new avenues for understanding disease mechanisms related to membrane dynamics.

Subramaniam Ganeshمشاهده پروفایل

استاد

• Neurodegenerative disorders
• Human molecular genetics
• Protein quality control
• +۳ مورد دیگر

Subramaniam Ganesh is a Professor at the Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur (IITK). His research focuses on neurodegenerative disorders, particularly Lafora disease, and the molecular genetics of protein misfolding and autophagy. Education: BSc (1988), MSc (1990) from University of Madras, PhD (1996) from Banaras Hindu University Professional Affiliations: IITK (2002–present), RIKEN Brain Science Institute (1998–2002), Indian Institute of Science (1997–1998) Research Interests: Dr. Ganesh's work spans three main areas: (1) molecular pathology of Lafora disease through genetic screening and cellular models, (2) mechanisms of disorders caused by amino acid repeat expansions with focus on polyglutamine toxicity, and (3) genetic determinants of complex disorders like stroke and asthma. His group employs clinical genetics, cell biology, and biochemical approaches to uncover shared mechanisms in neurodegenerative diseases. Publication Trends: Recent articles highlight his work on glycogen metabolism in neurodegeneration, autophagy regulation in Lafora disease, and cross-disciplinary studies linking diabetes to Alzheimer's pathology. Keywords across 15 most recent papers include Neuroscience , Genetics , Biochemistry , and Pharmacology , with sub-fields spanning Protein degradation , Metabolic stress , and Neuroinflammation . Scientific Awards: National Bioscience Award for Career Development (2008) Scopus Young Indian Scientists Award (2008) B.M. Birla Science Prize (2008) DAE-SRC Outstanding Research Investigator Award (2010) CDRI Award (2012) ICMR Basanti Devi Amir Chand Prize (2014) OPPI Scientist Award (2016) Advising & Collaborations: Mentored 30+ PhD/MSc students since 2002. Collaborated with institutions like RIKEN, IISc Bangalore, and CDRI Lucknow. Editorial roles include Chief Editor of IITK Directions and Associate Editor of Journal of Genetics . Laboratory & Team: Head of the Ganesh Laboratory at IITK, overseeing 20+ researchers including postdoctoral fellows, PhD students, and technical staff. Key projects involve molecular pathways in Lafora disease, protein quality control, and neurodegenerative therapeutics.