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نمایش ۱۶-۳۰ از ۳۳۵ استاد راهنما

اطلاعات پروفایل‌ها از صفحات عمومی دانشگاه‌ها گرفته شده و ممکن است به‌روز نباشد.

Rebecca A. Wingertمشاهده پروفایل

دانشیار

University of Notre DameUnited States

Rebecca A. Wingert is the Elizabeth and Michael Gallagher Associate Professor in the Department of Biological Sciences at the University of Notre Dame, where she also serves as Director of Graduate Studies and Chair of the Institutional Animal Care and Use Committee. Her research focuses on the genetic and molecular mechanisms of renal stem cells in kidney development, regeneration, and disease. Research Interests: The Wingert Lab investigates how renal stem cells contribute to nephron formation, homeostasis, and regeneration after injury. Her work addresses fundamental questions in developmental biology, stem cell biology, and organogenesis, with implications for understanding birth defects and chronic kidney diseases. Using zebrafish models, her lab explores conserved genetic pathways in vertebrate kidney development. Developmental Biology Stem Cell and Regenerative Biology Genetics & Genomics Molecular Biology Nephrology and Kidney Disease Rare and Neglected Diseases (e.g., Non-Ketotic Hyperglycinemia) Recent Research Trends: Analysis of her recent publications reveals a strong focus on transcriptional regulation (e.g., Tfap2a, Irx2a, Emx1), prostaglandin signaling, ciliogenesis, and nephron segmentation. Her lab uses zebrafish to model human renal diseases and uncover conserved mechanisms of nephrogenesis and repair. There is a recurring emphasis on metabolic regulation (e.g., PGC-1α) and injury response pathways. Scientific Awards and Recognition: Gallagher Family Professorship in Stem Cell Biology Advising and Grants: As Director of Graduate Studies, Dr. Wingert plays a central role in mentoring graduate students in the Department of Biological Sciences. While specific grant funding is not listed, her sustained productivity and leadership roles suggest active external support for her research program. She advises graduate students and postdoctoral researchers in her lab, fostering training in developmental genetics and renal biology. Labs and Research Teams: The Wingert Lab at the University of Notre Dame utilizes zebrafish as a model system to study kidney development and regeneration. The lab integrates forward and reverse genetics, chemical screening, and molecular imaging to dissect nephrogenesis and disease mechanisms. Her team collaborates across disciplines to model rare diseases and explore regenerative pathways.

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Dean Tantinمشاهده پروفایل

استاد

University of UtahUnited States

Dean Tantin is a Professor of Microbiology and Immunology at the University of Utah School of Medicine, where his research delves into gene regulation in T cells, stem cells, and cancer. His lab investigates how transcription factors like Oct1, Oct4, and OCA-B control stem-like properties in cells, impacting immunological memory, autoimmunity, and cancer progression. Education: B.S. – University of California, San Diego Ph.D. – University of California, Los Angeles Research Interests: Dr. Tantin’s work centers on understanding how transcription factors regulate cell fate decisions, particularly in T cells and stem cells. His lab explores the roles of Oct1 and Oct4 in pluripotency and differentiation, the function of OCA-B in T cell memory and autoimmunity, and the therapeutic potential of targeting these factors in diseases like multiple sclerosis and type 1 diabetes. A major focus is on how these transcription factors control gene expression programs that endow cells with longevity, self-renewal, and rapid response capabilities. Article Trends: Recent publications highlight a strong emphasis on transcriptional regulation in immune cells, particularly CD4+ T cells, and stem cells. Studies explore how OCA-B and Oct factors influence T cell memory formation, autoimmune responses, and cancer development. The work bridges molecular mechanisms with translational applications, including potential drug targets for autoimmune diseases and cancer. Laboratory and Team: Dr. Tantin leads an active research group at the University of Utah, supported by training grants and core facilities. His lab employs molecular biology, genomics, and in vivo models to dissect transcriptional networks. While specific student names are not listed, his mentorship is evident through his involvement in bioscience PhD programs and collaborative projects.

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Andreia Marina Ionescuمشاهده پروفایل

دانشیار

Northeastern UniversityUnited States

Dr. Andreia Marina Ionescu serves as Associate Professor of Biology and Principal Investigator at Northeastern University since July 2020, leading research in skeletal development and regenerative medicine. Education: PhD, University of Rochester (NY) Postdoctoral Fellowship, Harvard Medical School Research Interests: Her lab pioneers investigations into growth plate stem cell hierarchies, FoxA2+ long-term skeletal stem cells (LTSSCs), and osteoarthritis mechanisms. Key focuses include: Transcriptional regulation of chondrocyte differentiation Cartilage regeneration via stem cell populations Nanoparticle-based gene delivery for OA treatment PTHrP signaling in skeletal growth Publication Trends: Recent work (2022-2024) demonstrates integration of single-cell transcriptomics with functional studies to map skeletal stem cell lineages, revealing FoxA2+ LTSSCs as critical regeneration mediators. Parallel efforts develop charge-reversed exosomes for targeted cartilage therapy, bridging developmental biology and translational orthopedics. Scientific Awards: NSF CAREER Award (2024) Advising and Grants: Mentors four graduate students, twelve undergraduate researchers, and two senior scientists. Lab operations are supported by NSF CAREER funding and institutional resources for skeletal biology research. Lab and Team: The Ionescu lab integrates wet-lab biologists (Dr. Muruganandan Shanmugam, Dr. Yu Zhou) with computational expertise (bioinformatician Dr. Yu Zhou) to address skeletal regeneration challenges through molecular, cellular, and tissue-level approaches.

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Ala Trusinaمشاهده پروفایل

دانشیار

University of CopenhagenDenmark

Ala Trusina is an Associate Professor at the Niels Bohr Institute , University of Copenhagen , specializing in Biocomplexity and Biophysics . Her research integrates coarse-grained modeling to study complex biological systems. Key Research Areas Stress Response Systems (diabetes, aging, cancer, inflammation) Stem Cell Differentiation (cell fate coordination, reversibility of states) Complex Systems (species coexistence, epidemics, CRISPR-phage interactions) Methodologies Theoretical: Agent-based modeling, in-silico simulations Experimental: Quantitative single-cell imaging, RNA/protein profiling Collaborations Joshua Brickman (ES cells), Anne Grapin-Botton (pancreas), Feroz Papa (diabetes), Else Kai Hoffman (p53 dynamics) Thomas Mandrup-Poulsen (inflammation), Savas Tay (spatio-temporal regulation) Teaching Physics of Molecular Diseases Numerical Methods in Physics

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Basil Petrofمشاهده پروفایل

استاد

McGill UniversityCanada

Basil Petrof, MD is a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) at the Glen site, where he leads research in the Translational Research in Respiratory Diseases Program within the Centre for Translational Biology. He is also a Professor in the Department of Medicine at McGill University's Faculty of Medicine and Health Sciences, with a focus on the Division of Respiratory Medicine at the McGill University Health Centre. Dr. Petrof's research primarily focuses on disorders of the diaphragm and other breathing muscles, investigating both genetic conditions like muscular dystrophies and Pompe disease, as well as acquired conditions such as ventilator-induced diaphragmatic dysfunction in critically ill patients. His laboratory examines the cellular and molecular mechanisms contributing to respiratory muscle weakness, with the goal of developing novel therapies to prevent or reverse these conditions. His research spans several key areas including diaphragm physiology, muscular dystrophy, ICU-acquired muscle weakness, sepsis, and neuromuscular respiratory failure. Dr. Petrof employs a range of techniques from molecular biology to clinical studies, with a strong emphasis on translational research that bridges basic science discoveries to clinical applications. Dr. Petrof has made significant contributions to understanding ventilator-induced diaphragmatic dysfunction, respiratory muscle failure in neuromuscular diseases, and potential therapeutic interventions for muscular dystrophies. His work has been influential in shaping clinical approaches to managing respiratory complications in critically ill patients and those with neuromuscular disorders. As a Senior Scientist at RI-MUHC and Professor at McGill University, Dr. Petrof mentors numerous graduate students, postdoctoral fellows, and clinical researchers, contributing to the next generation of respiratory medicine specialists and scientists. His laboratory work involves collaborations across multiple disciplines, including immunology, molecular biology, and clinical respiratory medicine, reflecting the interdisciplinary nature of modern respiratory research.

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Tao Wuمشاهده پروفایل

استادیار

Baylor College of MedicineUnited States

Tao Wu is an Assistant Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine in Houston, TX. His research focuses on deciphering epigenetic mechanisms underlying cancer therapeutic resistance, particularly exploring DNA modifications like N6-methyladenine (6mA) and their roles in glioblastoma and other cancers. He employs advanced genomic technologies such as SMRT-ChIP and single-cell sequencing to study epigenetic regulators and their functional implications. Dr. Wu received his PhD from the University of Chinese Academy of Sciences (2008) and completed postdoctoral training at the Yale Stem Cell Center. His work integrates systems biology, genomics, and biochemistry to identify novel epigenetic drug targets. Key discoveries include identifying ALKBH1 as a 6mA demethylase and revealing 6mA’s role in hypoxia response pathways linked to drug resistance in glioblastoma. His research interests emphasize understanding dynamic epigenetic regulation in cancer, with projects focused on: Elucidating driver epigenetic mutations in cancer progression Developing therapies to overcome treatment resistance via epigenetic modulation Characterizing novel DNA modifications (e.g., 6mA) and their regulatory mechanisms Recent work highlights the lab’s focus on single-molecule sequencing and CRISPR-based screening to uncover epigenetic pathways in cancer models. Funding support includes grants from the Cancer Prevention Research Institute of Texas (CPRIT).

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Amy Cherie Ralstonمشاهده پروفایل

استاد

Michigan State UniversityUnited States

Amy Cherie Ralston is a Professor at Michigan State University's College of Natural Science in the Department of Biochemistry & Molecular Biology , where she also serves as Associate Dean - Graduate Studies . Her research focuses on the genetic and molecular mechanisms governing early mouse embryonic development, particularly the specification of pluripotent and extraembryonic lineages. Education: Ph.D. in Zoology, University of Wisconsin (2004) B.A. in Biochemistry, Oberlin College (1995) Research Interests encompass mouse embryonic development, pluripotent stem cell regulation, HIPPO signaling pathway functions, and transcription factor dynamics during lineage specification. She has extensively studied the roles of OCT4, SOX2, Cdx2, and TEAD4 in developmental fate determination. Publications highlight trends in mouse blastocyst lineage segregation, stem cell maintenance mechanisms, and signaling pathway interactions. Notable work includes studies on HIPPO pathway members' restriction of pluripotency factors and culture condition impacts on developmental signaling. Students and Lab : Dr. Ralston leads the Ralston Laboratory, mentoring graduate and postdoctoral researchers in developmental biology and stem cell research. While specific student names aren't listed, her lab's work has produced significant insights into extraembryonic endoderm stem cell lines and transcription factor functions in reprogramming.

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Cassandra G. Extavourمشاهده پروفایل

استاد

Harvard UniversityUnited States

Cassandra G. Extavour is the Timken Professor of Organismic and Evolutionary Biology and Molecular and Cellular Biology at Harvard University, and a Howard Hughes Medical Institute Investigator. She holds a joint appointment in the Department of Molecular and Cellular Biology and is affiliated with Harvard College. Her research focuses on the evolution and development of germ cells and reproductive systems in arthropods, particularly exploring mechanisms of germ cell specification and the evolutionary transitions in developmental processes. Extavour's work integrates molecular genetics, comparative embryology, and evolutionary theory to study model organisms like spiders, crickets, and fruit flies. She leads the Extavour Lab at Harvard's Biological Laboratories, which collaborates with institutions globally. Notable contributions include discoveries about germ cell specification diversity across arthropods and the role of developmental constraints in life-history evolution. Her educational roles include teaching courses on invertebrate biology and integrated science at Harvard. Recent accolades include her HHMI Investigator status and recognition in Quanta Magazine for career contributions. The lab actively engages in genomic projects, such as cricket genome analysis, and explores molecular mechanisms underlying evolutionary innovations. Students and postdocs in her lab investigate topics ranging from germ line determinants to symbiotic influences on gene evolution.

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Randolph Ashtonمشاهده پروفایل

استاد

University of Wisconsin-MadisonUnited States

Randolph Ashton is a Professor in the Department of Biomedical Engineering at the University of Wisconsin-Madison College of Engineering. He directs the Stem Cell Bioprocessing and Regenerative Biomaterials Laboratory, where his team engineers novel materials and methodologies for lineage-specific differentiation of human pluripotent stem cells. His interdisciplinary research bridges biomaterials science, stem cell biology, and tissue engineering to develop regenerative therapeutic strategies. His educational background includes: PhD (2007) from Rensselaer Polytechnic Institute BS (2002) from Hampton University Ashton's research focuses on neural and vascular tissue engineering , with specialization in regenerative therapies for the central nervous system. His laboratory employs microfabrication, molecular biology, recombinant protein engineering, and automated live-cell imaging to investigate cellular microenvironmental factors regulating stem cell fate. Current work emphasizes developing high-throughput screening methods and tissue-engineered scaffolds for generating complex tissue structures in vitro. His recent publications reveal a strong trajectory in neural organoid development, CNS vascularization, and microphysiological systems. The research demonstrates quantitative approaches to understanding stem cell differentiation, with applications spanning from fundamental developmental biology to clinical regenerative medicine. Key technological innovations include advanced microelectrode arrays and high-throughput screening platforms for neural tissue engineering. Notable awards include: 2023 AIMBE Fellowship 2020 WARF Innovation Award 2018 UW-Madison College of Engineering Equity & Diversity Award 2017 NSF CAREER Award 2016 Regenerative Medicine Workshop Young Investigator Award Ashton actively mentors graduate students through thesis research (BME 890, BME 990) and teaches core courses including Biological Interactions with Materials (BME 430). His laboratory operates as an interdisciplinary team bringing together engineering, biology, and materials science expertise to develop regenerative therapies, with current focus on central nervous system applications and expanding interests in vascular and muscular tissues. The Stem Cell Bioprocessing and Regenerative Biomaterials Laboratory maintains active collaborations across disciplines and continues to develop novel approaches for high-order tissue structure generation using human pluripotent stem cells. Current research directions include expanding into vascular and muscular tissue systems while refining quantitative methodologies for stem cell microenvironment characterization.

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John Achermannمشاهده پروفایل

استاد بالینی

University College LondonUnited Kingdom

Prof John Achermann is a Clinical Professor of Paediatric Endocrinology at the Genetics & Genomic Medicine Department , University College London (UCL), with an active role at the UCL GOS Institute of Child Health since 2023. His career spans clinical and research expertise in adrenal and sex development , genetic mechanisms of disease , and nuclear receptor biology , highlighted by over 200 publications and an h-index of 67. Education: Bachelor of Arts (Honours), University of Cambridge (1988) Bachelor of Medicine, University of Cambridge (1990) Master of Arts, University of Cambridge (1992) Doctor of Medicine (MD), University of Cambridge (1997) Doctor of Philosophy (PhD), University of Cambridge (2011) His research focuses on molecular genetics of adrenal and reproductive development , integrating transcriptomics and genomic medicine to understand disorders like Turner syndrome, Disorders of Sex Development (DSD), and adrenal insufficiency. Recent work includes single-cell analyses of fetal gonads , exome sequencing for DSD/POI , and NR5A1/SRY regulatory mechanisms . Key awards include the 2025 ESPE Research Award , 2023 Henning Andersen Prize , and 2016 Clinical Endocrinology Trust Lecturer Medal . Scientific Awards: ESPE Research Award (2025) Henning Andersen Prize (2023, 2007) Clinical Endocrinology Trust Lecturer Medal (2016) SPARKS/RCPCH Young Investigator (2007) ESPE Young Investigator (2002) Noble Prize for MD Thesis (1998) As Head of the Molecular Basis of Rare Disease Section and Deputy Head of Genetics & Genomic Medicine at UCL GOS Institute of Child Health, he bridges clinical practice with translational research. He contributes to undergraduate and postgraduate medical education , supervises MSc projects, and serves on the ESPE Local Organising Committee for 2024. His work aligns with UN Sustainable Development Goals for Good Health & Well-Being and Gender Equality .

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Valerie Kouskoffمشاهده پروفایل

دانشیار

The University of ManchesterUnited Kingdom

Valerie Kouskoff is a Reader in the Division of Developmental Biology and Medicine at the University of Manchester, UK (2016–present). Previously, she held roles including Group Leader at the CRUK Manchester Institute (2003–2016) and Assistant Professor at Mount Sinai School of Medicine, New York (2002–2003). She earned her PhD from Louis Pasteur University, Strasbourg, France (1988–1994). Her research focuses on understanding hematopoietic stem cell (HSC) development during embryogenesis, particularly the endothelial-to-hematopoietic transition and genetic/epigenetic mechanisms regulating blood cell specification. Key areas include the role of transcription factors (RUNX1, SOX7, GFI1), hemogenic endothelium differentiation, and therapeutic applications of stem cell engineering. Her work contributes to UN Sustainable Development Goals related to health and regenerative medicine. Recent articles highlight advancements in AML treatment via KAT6A inhibitors, CD82’s role in blood specification, and SOX7-dependent lymphatic patterning. Collaborations span institutions like the Manchester Regenerative Medicine Network and Christabel Pankhurst Institute. She has supervised 8 research projects and published over 100 peer-reviewed articles. Her studies explore genomic instability in cancer, reprogramming fibroblasts to hematopoietic cells, and the interplay between vascular and blood development.

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Raf Hussainمشاهده پروفایل

پژوهشگر

Newcastle UniversityUnited Kingdom

Immunology
Genetics
Molecular Biology
+۷ مورد دیگر

Raf Hussain is a researcher at Newcastle University with extensive contributions to immunology, genetics, and ocular biology. Their work spans from 2002 to 2025, focusing on disease mechanisms in aging, cancer, and eye disorders. University: Newcastle University Academic Role: Researcher Research interests include: Regulatory T cell communication patterns in aging populations Immune dysregulation in autoimmune diseases like psoriatic arthritis Role of PD-1 receptor deficiency in melanoma progression Stem cell biology applications in papillary cancer and retinal diseases Genotype-phenotype correlations in Stargardt disease Recent publications highlight collaborations in single-cell sequencing, mitochondrial DNA variation, and ocular immunity. The work spans both fundamental developmental biology (retinal progenitor cells) and translational medicine (SARS-CoV-2 ocular entry routes).

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Keith Lathamمشاهده پروفایل

استاد

Michigan State UniversityUnited States

Keith Latham is a Professor at Michigan State University affiliated with the Cell & Molecular Biology Program and Genetics & Genome Sciences Program. His research focuses on molecular mechanisms regulating early mammalian embryogenesis and disease origins from developmental disruptions. Cell & Molecular Biology Program Faculty Genetics & Genome Sciences Program Faculty Research Interests His work explores embryonic development , epigenetics , and reproductive biology , emphasizing how maternal/paternal factors influence embryo viability. Recent studies investigate FSH effects on ovarian stimulation, oocyte transcriptome regulation, and mitochondrial dysfunction transmission via oocytes. Scientific Awards Advising and Grants No student advising or grant information is provided in the text. Further details may exist in external academic records.

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Marco Prinzمشاهده پروفایل

استاد

Max Planck Institute for Molecular BiomedicineGermany

Professor Marco Prinz serves as Principal Investigator leading the Innate Immunity research group at the Institute of Neuropathology, University of Freiburg Faculty of Medicine. His laboratory investigates the critical role of brain-specific innate immune cells, particularly microglia, in neurological health and disease. Dr. Prinz's research focuses on understanding how microglia—the brain's resident macrophages—contribute to both protective and pathological processes in the central nervous system. His work examines microglial function in neuroinflammation, neurodegeneration, and autoimmune conditions like multiple sclerosis using advanced mouse models including EAE and cuprizone models. A significant portion of his recent research employs single-cell analysis techniques to characterize the heterogeneity of microglial cells in various disease states, particularly in chronic active lesions and paramagnetic rim lesions in MS patients. The laboratory has made important contributions to understanding microglial development, showing how these cells emerge from specific precursors and establish themselves in defined niches within the CNS. Their work has revealed how microglia act as both guardians and potential contributors to neurological damage, with implications for Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Dr. Prinz's research team includes multiple postdoctoral researchers, PhD students, and technical staff who contribute to ongoing investigations into CNS immunity. His laboratory has pioneered techniques for studying microglia, including novel genetic tools and single-cell analysis approaches that have provided unprecedented insights into the cellular composition of brain lesions and the dynamic behavior of immune cells in neurological disorders.

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Daniel Jeffaresمشاهده پروفایل

مدرس ارشد

University of YorkUnited Kingdom

Dr. Daniel Jeffares is a Senior Lecturer in the Department of Biology at the University of York. His research focuses on Leishmania genomics, population genetics, and quantitative genetics, with an emphasis on understanding evolutionary processes and molecular biology in parasitic organisms. His work contributes to global health initiatives, including collaborations through the UK-Brazil Joint Centre Partnership in Leishmaniasis (JCPiLeish) and the PREV_PKDL project analyzing visceral leishmaniasis in East Africa. He leads the Jeffares Lab, which utilizes advanced genomic techniques to study parasite evolution and pathogenesis. Research Interests: Leishmania population genomics and drug resistance Genomic analysis of co-infections and pathogen diversity Evolutionary adaptations in trypanosomatids and extremophiles Applications of genomic methods in disease research Awards : Recipient of the Visiting Professorship (2022), recognizing his contributions to collaborative research and capacity-building in genomic methodologies. Grants & Collaborations: Principal Investigator on projects funded by MRC, Wellcome Trust, and NERC Leadership in multidisciplinary initiatives addressing visceral leishmaniasis in Sudan, Ethiopia, Uganda, and Kenya Active partnerships with institutions in Brazil and global health networks Labs/Teams: The Jeffares Lab at the University of York, part of the Biology Department’s research cluster focusing on microbial genomics and evolutionary processes.

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