جست‌وجوی استاد و پژوهشگر

• Eukaryotic RNA processing
• Post-transcriptional gene regulation
• Spliceosome structure and mechanism
• +۶ مورد دیگر

Melissa J. Moore, PhD, is Professor at the University of Massachusetts Chan Medical School, where she holds the Eleanor Eustis Farrington Chair of Cancer Research and serves in the RNA Therapeutics Institute. She also holds appointments in the T. H. Chan School of Medicine (Department of Chemical Biology) and the Morningside Graduate School of Biomedical Sciences (Departments of Biochemistry & Molecular Biotechnology, Interdisciplinary Graduate Program, and Translational Science). Additional affiliations include campus-wide programs in Bioinformatics & Integrative Biology and Chemical Biology. Education: BS in Chemistry/Biology, College of William and Mary PhD in Biological Chemistry, Massachusetts Institute of Technology Research Focus: Melissa Moore’s laboratory investigates post-transcriptional gene regulation in eukaryotes, with emphasis on three interconnected themes: (1) spliceosome structure and catalytic mechanism, (2) nuclear-to-cytoplasmic control of mRNA metabolism, and (3) quality control and clearance of defective ribosomal and messenger RNAs. The group combines biochemistry, single-molecule biophysics, RNA structural biology, and cell biology to dissect these processes at molecular and systems levels. Scientific Awards & Honors: Eleanor Eustis Farrington Chair of Cancer Research Funding & Collaborations: Work is supported by grants from the National Institutes of Health and involves ongoing collaborations with investigators at Brandeis University, MIT, University of Rochester, and other institutions. Rotation projects for graduate students are available in all active research areas. Laboratory & Team: The Moore laboratory is located in the RNA Therapeutics Institute at UMass Chan Medical School, 364 Plantation Street, Worcester, MA. The team employs state-of-the-art single-molecule imaging, mass spectrometry, and high-throughput sequencing to advance understanding of RNA biology and to translate insights into therapeutic RNA technologies.

• Mitochondrial Biology
• Aging Research
• Genomic Instability
• +۳ مورد دیگر

Sharath Anugula serves as a Guest Researcher in the Department of Cellular and Molecular Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences, specifically within the Molecular Aging Program and Juel-Rasmussen Group. His research is centered at Panum Instituttet in Copenhagen. Dr. Anugula's research interests focus on the intricate relationship between mitochondrial function, genomic stability, and aging processes. His work bridges molecular biology, genetics, and systems approaches to understand fundamental mechanisms of biological aging. He has made significant contributions to understanding how DNA repair mechanisms, particularly REV1-mediated processes, interact with mitochondrial metabolism in aging contexts. His publication record demonstrates expertise in mitochondrial biology, with research examining how metabolic shifts, genomic instability, and nucleotide synthesis pathways influence aging trajectories and disease development. His work often employs both experimental and computational approaches to model complex biological systems. Anugula completed his Ph.D. at the University of Copenhagen in 2021 with research focused on nucleus-mitochondria communication in healthy aging. His scholarly output includes journal articles in Heliyon, Mitochondrion, and Experimental Gerontology, as well as book chapters on aging biology. His collaborative research network includes prominent scientists in aging research, particularly Professor Lene Juel Rasmussen, with whom he has published multiple studies examining the molecular underpinnings of aging processes.

Ben Z. Stangerمشاهده پروفایل

استاد

• Pancreatic Cancer
• Cellular Plasticity
• Tumor Immunology
• +۳ مورد دیگر

Ben Z. Stanger, M.D., Ph.D. is the Hanna Wise Professor in Cancer Research at the University of Pennsylvania's Perelman School of Medicine, with appointments in the Department of Medicine and Cell and Developmental Biology. He serves as Director of the Penn Pancreatic Cancer Research Center (PCRC) and is an active member of the Abramson Cancer Center, Institute for Diabetes, Obesity and Metabolism, Institute for Medicine and Engineering, and Institute for Regenerative Medicine. His laboratory is housed in the Biomedical Research Building II/III on the Penn campus in Philadelphia. Education: SB (Life Sciences) from Massachusetts Institute of Technology, 1988 MD and PhD (Genetics) from Harvard Medical School, 1997 Dr. Stanger's research focuses on pancreatic ductal adenocarcinoma (PDAC), which is poised to become the second leading cause of cancer death in the United States. His laboratory investigates how pancreatic tumors metastasize early in disease progression and identifies therapeutic vulnerabilities through studies of the tumor microenvironment, metabolism, cellular plasticity, and metastasis biology. His team employs genetically engineered mouse models that recapitulate human disease features, functional genomics, epigenetic analyses, and advanced in vitro culture systems. Analysis of Dr. Stanger's recent publications (2019-2024) reveals a consistent focus on pancreatic cancer biology with increasing emphasis on tumor immunology and therapeutic resistance mechanisms. His research has evolved from fundamental studies of tumor-stroma interactions toward more translational investigations of KRAS inhibition, immune microenvironment regulation, and cellular reprogramming in cancer. Recent work demonstrates how tumor plasticity drives resistance to immunotherapy and how metabolic adaptations allow cancer cells to survive nutrient-deprived conditions. Dr. Stanger maintains an active laboratory with diverse personnel including postdoctoral researchers, graduate students, research specialists, and administrative support. His lab has published in high-impact journals including Nature Communications, Cancer Discovery, Cancer Research, and Science. In addition to his research, Dr. Stanger has authored the book "From One Cell: A Journey into Life's Origins and the Future of Medicine" which explores embryonic development through the lens of scientific history. Research Team: Principal Investigator: Ben Stanger, MD, PhD Research Specialists: Chenghua Yang (Lab Manager), Lily Watson (Assistant Lab Manager) Research Coordinator: Sean O'Connor Postdoctoral Researchers: Austin Good, Cole Edwards, Feiyan Mo, Minh Than Graduate/Post-Graduate Students: Erin Hollander, Benjamin Kahn, Jayne McDevitt, Margo Orlen, William Sullivan, Jane Xie Undergraduate Researcher: Shreya Nair Executive Administrator: Fran Tucker

Sandhya Ganesanمشاهده پروفایل

استادیار

• Host-Pathogen Interaction
• Innate Immunity
• Molecular Biology
• +۷ مورد دیگر

Dr. Sandhya Ganesan is an Assistant Professor at the School of Biology , Indian Institute of Science Education and Research Thiruvananthapuram (IISER-TVM) , where she established the Host-Pathogen Interaction Lab in January 2022. Her research focuses on mammalian molecular pathways that detect, respond to, and control bacterial pathogens like Coxiella burnetii , Legionella , and Candida albicans . Academic Rank: Assistant Professor University: Indian Institute of Science Education and Research Thiruvananthapuram (IISER-TVM) School: School of Biology Education: Ph.D. in Biomedical Sciences (Immunology and Microbiology Program), University of Massachusetts Chan Medical School (2014) B. Tech (with distinction) in Industrial Biotechnology, Alagappa College of Technology, Anna University (2007) Research Interests: She investigates host-pathogen interactions , innate immunity , and cell-intrinsic defense mechanisms , particularly how pathogens manipulate host immune surveillance. Her work includes studying inflammasome signaling, SNARE protein functions, and lysosomal biogenesis in pathogen control. Publication Trends: Her publications span immunology , molecular biology , and microbiology , emphasizing inflammasome pathways (e.g., NLRC4, AIM2, NLRP3), SNARE proteins (STX11), and IFNγ-induced host factors. Key subfields include pathogen-containing vacuole composition , lysosomal restriction , and immune dysregulation in disease . Scientific Awards: Milstein Abstract Award (2021) American Association of Immunologists (AAI) Trainee Abstract Award (2020) Professional Activities: She has peer-reviewed for journals like Bio-protocol , Infection and Immunity , and Scientific Reports , and organized the 2020 Intersections Science Fellows Symposium.

• Liver Immunology
• Immune Tolerance
• Transplant Immunology
• +۵ مورد دیگر

Associate Professor Patrick Bertolino at the University of Sydney's Central Clinical School leads the Liver Immunology Program at the Centenary Institute. With 20+ years of international recognition in liver immunology , he pioneered discoveries about CD8+ T cell activation and hepatocyte-mediated immune tolerance , including the paradigm-shifting finding that liver-activated T cells are deleted via hepatocyte lysosomes. His work bridges transplantation immunology , chronic hepatitis , and malaria vaccine development using transgenic mouse models . Trained by immunology luminaries: Chantal Rabourdin-Combe (ENS-Lyon), Jacques Miller (WEHI), Barbara Fazekas de St Groth (Centenary Institute) Continuous NHMRC funding since 2000: 2 Program Grants, 6 Project Grants 2010 NHMRC Senior Research Fellowship Research Themes explore how the liver uniquely regulates immunity: Induces transplant tolerance via T cell deletion Exploits immune subversion in hepatitis B/C and malaria Develops gene therapy and mRNA vaccines for liver-targeted immunity Investigates hepatitis C reinfection post-transplant Article Trends show sustained focus on T cell-liver interactions , with recent work on mRNA vaccines (2023), neuroinflammation in GVHD (2024), and long-lived TRM cells in malaria (2025). Publications span high-impact immunology , hepatology , and transplantation journals . Awards include: 2010 NHMRC Senior Research Fellowship 2009 Centenary Institute student paper award 1999 Kevin Lafferty Prize for Autoimmunity 1997 University of Sydney U2000 Fellowship Teaching includes 3rd-year Immunology lectures (since 1998). Led liver immunology group since 2011, mentoring students and postdocs. Collaborates with Centenary Institute and National Hepatitis C Elimination Program .

• Biomaterials
• Microbiology
• Biomaterial-associated infections
• +۵ مورد دیگر

Hendrik Jan (Henk) Busscher is a Professor Emeritus in the Department of Biomedical Engineering at the University of Groningen, affiliated with the Faculty of Medical Sciences and the W.J. Kolff Institute. His research focuses on biomaterial-associated infections, microbial adhesion mechanisms, and surface modification strategies to prevent biofilm formation on medical implants. He has held leadership roles, including Head of the Department of Biomedical Engineering and Director-owner of consulting firm SASA BV, and serves as Editor of Colloids and Surfaces B: Biointerfaces . Research interests include physico-chemical interactions of biomaterials with biological components, antibiotic resistance, and nanotechnology applications in infection control. He has supervised over 79 PhD students and authored >636 publications, achieving an H-index of 58. Key contributions span biofilm dynamics, surface characterization techniques, and in vitro/in vivo infection models. His work emphasizes translational research, bridging academic and industrial partnerships in biomaterials innovation. Recent studies explore quantum dot synthesis for biomedical applications, pH-responsive drug delivery systems, and magnetic nanoparticle-based antibacterial strategies. Collaborations include global institutions and companies like Philips and Procter & Gamble. His interdisciplinary approach addresses sustainable healthcare challenges, particularly in preventing infections from medical devices.

Michael B. Yaffeمشاهده پروفایل

استاد

• Cancer Biology
• Signal Transduction
• Precision Medicine
• +۷ مورد دیگر

Michael B. Yaffe is the David H. Koch Professor of Science and Professor of Biology and Biological Engineering at MIT, where he has been a faculty member since 2000. He serves as Director of the MIT Center for Precision Cancer Medicine and the KI Clinical Investigator Program. Clinically, he is an attending surgeon and intensivist at Beth Israel Deaconess Medical Center, specializing in injury and surgical oncology. Education: MD-PhD from Case Western Reserve University Training: Residency at University Hospitals of Cleveland; Fellowship at Harvard-Longwood Critical Care Program Dr. Yaffe's research focuses on protein kinase signaling pathways activated by DNA damage, cell injury, and inflammation. His work explores how these pathways regulate cancer behavior and treatment response through integrated experimental and computational approaches, with translational applications in systems pharmacology and precision medicine. His 15 most recent publications span DNA damage responses, mitotic stress, immunogenic cell injury, kinase signaling atlases, and reproducibility in science. Key trends include targeting pathway crosstalk for therapeutic synergy, leveraging R-loops in DNA repair-deficient tumors, and understanding immune activation post-chemotherapy. Scientific Awards: HHMI Physician-Scientist Fellowship Burroughs-Wellcome Fund Award MacVicar Faculty Fellow (2021) Association of American Physicians (2021) American Surgical Association membership Dr. Yaffe advises trainees in scientific career development and leads the Yaffe Lab at MIT, which pioneers novel technologies like peptide libraries and multiplex kinase reporters. His work bridges benchtop experiments with clinical applications in chemotherapy, radiation, and surgery, while also addressing inflammation-cancer connections.

Laura Galazzoمشاهده پروفایل

مدرس

• Biophysics
• Protein Dynamics
• Molecular Biophysics
• +۳ مورد دیگر

Dr. Laura Galazzo is a Lecturer at the Department of Chemistry and Applied Biosciences, ETH Zurich, affiliated with the Institute of Molecular Physical Sciences (IMPS). Her research focuses on biophysical chemistry and molecular dynamics, employing advanced spectroscopic techniques like Electron Paramagnetic Resonance (EPR) to study protein structure, phase transitions, and membrane transport mechanisms. She investigates topics such as liquid-liquid phase separation in proteins, ABC transporter function, and nitroxide radical dynamics in aqueous environments. Dr. Galazzo also contributes to methodological advancements in pulsed dipolar spectroscopy and neural network applications in spectroscopic data analysis. Her work bridges theoretical and experimental approaches, combining computational methods (e.g., ab initio molecular dynamics) with experimental techniques to address complex biological systems. Key areas of study include protein aggregation, conformational changes in large complexes, and the interplay between solvent effects and biomolecular behavior. Recent research highlights include studies on mycobacterial iron uptake mechanisms and the structural dynamics of pro-apoptotic peptides. Dr. Galazzo’s publications reflect a strong emphasis on interdisciplinary approaches, integrating spectroscopy, computational modeling, and structural biology. Her contributions have advanced methodologies for distance measurements in biomolecules and provided insights into fundamental biological processes such as phase separation and membrane-mediated transport. She is actively engaged in promoting sustainable education through initiatives like the EquipSent project, aiming to enhance global access to scientific resources.

Aaron Mendezمشاهده پروفایل

استادیار

• Virology
• Molecular Biology
• Microbiology
• +۳ مورد دیگر

Aaron Mendez is an Assistant Professor in the Department of Molecular Biology and Microbiology at Tufts University School of Medicine. His research focuses on understanding how viruses maximize their replicative output through the formation of replication compartments, using Kaposi's sarcoma-associated herpesvirus (KSHV) as a model system. Education: PhD in Chemistry & Chemical Biology from the University of California, San Francisco (2015); BSc in Biochemistry & Molecular Biology from the University of California, Irvine (2009). Research Interests: The lab employs a multidisciplinary approach combining molecular virology, biochemistry, and chemical genetics to uncover molecular mechanisms underlying viral replication compartment formation. Key areas include compartment dynamics, viral machinery organization, and evasion of host immune responses. Recent work highlights studies on SOX exonuclease activity in KSHV and SARS-CoV-2 nsp1 protein function. Publications: Recent articles (2014–2023) explore viral replication mechanisms, ER stress pathways, and protein engineering. Notable contributions include elucidating SOX's role in viral DNA processing and characterizing SARS-CoV-2 nsp1's suppression of host gene expression. Grants & Lab Activities: The lab develops novel tools for studying viral replication compartments, with potential applications in antiviral strategies. Current efforts aim to identify linchpin interactions critical for compartment assembly and function. Labs/Teams: Mendez leads a research group focused on advancing virology through innovative biochemical and genetic methodologies.

Fabian-Xosé Fernandezمشاهده پروفایل

دانشیار

• Circadian Rhythms
• Sleep Science
• Suicide Risk Assessment
• +۳ مورد دیگر

Fabian-Xosé Fernandez serves as Associate Professor in the Department of Psychology within the College of Science at the University of Arizona, where he directs the Circadian Trends Laboratory. His research program bridges neuroscience, clinical psychology, and public health through investigations of circadian biology and sleep-wake patterns. His primary research interests focus on circadian fluctuations in real-world data , psychology of nighttime wakefulness , and suicide risk mechanisms . Key investigations explore how nocturnal wakefulness correlates with suicidal ideation, homicide risk, and metabolic dysregulation. His work employs National Violent Death Reporting System analyses Controlled circadian phase-shifting experiments Population-level sleep surveys Translational rodent models Recent publications reveal strong temporal patterns in behavioral health outcomes, with suicide risk peaking during circadian night across diverse populations. His lab develops chronotherapeutic interventions including spectral filtering devices and lighting protocols to optimize circadian alignment. Current work examines how blue-light modifiers affect phase-shifting responses and how sleep disruption mediates psychiatric outcomes in bipolar disorder. Fernandez teaches graduate and undergraduate courses including PSY 350 (Sleep/Wake, Time Cycles, & Life) and PSY 578 (Sleep & Sleep Disorders), with recent instruction through 2025. His academic service includes editorial review for journals like Clocks & Sleep and Neuropsychopharmacology.

Yulia Nefedovaمشاهده پروفایل

دانشیار

• Cancer Immunology
• Tumor Microenvironment
• Multiple Myeloma
• +۵ مورد دیگر

Dr. Yulia Nefedova is an Associate Professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute's Ellen and Ronald Caplan Cancer Center. She joined Wistar in 2013 as an assistant professor in the Tumor Microenvironment and Metastasis program, was promoted to associate professor in the Immunology, Microenvironment and Metastasis Program in 2017, and transitioned to her current position in the Molecular and Cellular Oncogenesis Program in 2024. Dr. Nefedova's research focuses on understanding molecular mechanisms by which the bone marrow microenvironment promotes tumor survival and progression, with particular emphasis on multiple myeloma. Her laboratory investigates how interactions between bone marrow neutrophils and multiple myeloma cells promote disease progression and chemoresistance, with specific interest in neutrophil extracellular traps (NETs) and the S100A9 protein. Analysis of her 15 most recent publications reveals a consistent focus on neutrophil biology within the tumor microenvironment, particularly their role in promoting cancer progression and therapy resistance. Her work spans immunology, cancer biology, and molecular oncology with increasing emphasis on therapeutic targeting of neutrophil-mediated processes. Dr. Nefedova's laboratory includes Research Assistant Melissa Haddadi and Lab Assistants Hsuan-Yu Lin and Hannah Lee. She maintains active collaborations with prominent researchers including Dr. Dmitry Gabrilovich, as evidenced by their frequent co-authorship.

• Neuroscience
• Cell Signaling
• Neurodegenerative Diseases
• +۵ مورد دیگر

Jose Ramon Bayascas Ramirez is an Associate Professor in the Department of Biochemistry and Molecular Biology at the Universitat Autònoma de Barcelona's Institute of Neuroscience. With a Ph.D. in Biological Sciences from the University of Barcelona (1998), he completed postdoctoral training at the University of Lleida (1998-2002) and University of Dundee, Scotland (2002-2007) before joining UAB in 2007 as a Ramon y Cajal Fellow, becoming a Serra Húnter Associate Professor in 2014. His research focuses on the neurodevelopmental functions of the $$\text{PDK1}$$ signaling network and its implications for neurodegenerative and mental illnesses. His laboratory specializes in the $$\text{PI3K}$$/$$\text{Akt}$$ signaling pathway, utilizing brain-specific conditional knock-in mice with engineered $$\text{PDK1}$$ mutations (K465E and L155E) to study how these affect neuronal development and disease processes. The K465E mutation selectively impairs $$\text{Akt}$$ activation, while the L155E mutation abolishes activation of most $$\text{PDK1}$$ effectors except $$\text{Akt}$$. His work has revealed that reduced $$\text{Akt}$$ activation in $$\text{PDK1}$$ K465E mice protects against neurodegenerative insults, while the exclusive $$\text{Akt}$$ activation in $$\text{PDK1}$$ L155E mice causes severe mental disorders resembling human schizophrenia. His recent publications span molecular insights into $$\text{PDK1}$$ structure, behavioral studies in Alzheimer's models, and investigations into lysine crotonylation and metabolic homeostasis. His research has been recognized with a Ramon y Cajal Fellowship, and he has led multiple research projects including: "Assaig de l'inhibidor d'$$\text{Akt}$$ MK-2206 pel tractament de la Malaltia d'Alzheimer" (2022-2023) "Implicació de la ruta de senyalització $$\text{PI3K}$$/$$\text{PDK1}$$/$$\text{Akt}$$ en la Malaltia d'Alzheimer" (2019-2022) "Participació de $$\text{PDK1}$$ en les respostes a $$\text{PI3K}$$ durant el desenvolupament neuronal" (2015-2018) His group has published 53 research outputs with significant citations, demonstrating impactful contributions to understanding the molecular mechanisms underlying brain pathology and potential therapeutic targets for neurodegenerative and mental disorders.

Jun Yamamotoمشاهده پروفایل

استادیار

• Neuroscience
• Cognitive Neuroscience
• Systems Neuroscience
• +۳ مورد دیگر

Jun Yamamoto is an Assistant Professor of Psychiatry Neuroscience at UT Southwestern Medical Center. He holds a Ph.D. in computer science from Keio University (Japan), with postdoctoral training at the University of Strasbourg Medical School and MIT's Picower Institute. His research focuses on neural dynamics underlying memory access and retrieval in hippocampal-cortical networks, particularly spatial topology, working memory, and schizophrenia models. He has developed advanced neurotechnologies like motorized microdrives for chronic neural recordings in freely moving animals. Education: Bachelor's, Master's, and Ph.D. in Computer Science, Keio University (Tokyo, Japan) Postdoctoral Fellowships: MIT Picower Institute (with Matt Wilson and Susumu Tonegawa) and University of Strasbourg Medical School Research Interests: Yamamoto's lab investigates hippocampal circuit mechanisms for memory formation, observational fear circuits, and reverse-translational models of psychosis. His work integrates experimental neuroscience, electrophysiology, and engineering to study neural activity in behaving animals. Lab & Collaborations: The Jun Yamamoto Lab at UT Southwestern explores neural network dynamics using cutting-edge techniques like optogenetics, calcium imaging, and computational modeling. They collaborate on projects involving hippocampal-amygdala circuits and schizophrenia pathophysiology.

Birgit Kemmerlingمشاهده پروفایل

پژوهشگر

• Plant Molecular Biology
• Plant Pathology
• Immunology
• +۵ مورد دیگر

Dr. Birgit Kemmerling is a research group leader at the Center for Plant Molecular Biology (ZMBP) within the Faculty of Science at the University of Tübingen, Germany. Her research focuses on molecular mechanisms of plant innate immunity, particularly the role of leucine-rich repeat receptor-like kinases (LRR-RLKs) in pathogen recognition and defense signaling. Key projects include studying BAK1 and BIR3 kinases involved in immune receptor complex formation and regulation. She collaborates with institutions worldwide and has secured funding from DFG and EU programs such as AFGN, Bravissimo, and SFB1101. Teaching responsibilities include lectures and seminars on comparative immunity in plants and animals, practical courses in molecular mechanisms of innate immunity, and supervision of bachelor/master theses. Her group actively engages in interdisciplinary projects, integrating nanotechnology studies to assess immune responses to nanoparticles across species. Notable collaborators include Prof. Thomas Boller (Basel), Cyril Zipfel (Norwich), and Frans Tax (Tucson). Research highlights include discovering BAK1's dual role in brassinosteroid signaling and immune response regulation, as well as identifying novel LRR-RLK genes activated by pathogen infection. Current work explores nanomaterial biocompatibility and immune system interactions, leveraging advanced microscopy techniques like super-resolution imaging (OneFlowTraX software development).

Jason Millsمشاهده پروفایل

استاد

• Paligenosis
• Cellular Reprogramming
• Stem Cells
• +۶ مورد دیگر

Dr. Jason Mills is the Herman Brown Endowed Professor at Baylor College of Medicine, where he serves as Chief of Research and Vice Chief in the Department of Gastroenterology & Hepatology. He is also Co-Director of the Texas Medical Center Digestive Disease Center and Co-Associate Director for Cancer Research Training and Education at the Dan L Duncan Comprehensive Cancer Center. Dr. Mills leads the Mills Lab, which focuses on cellular reprogramming and cancer mechanisms. Dr. Mills received his AB from Washington University in St. Louis (1989), followed by an MD-PhD from the University of Pennsylvania School of Medicine (1997). He completed his postdoctoral fellowship at Washington University Medical Center (2002). Dr. Mills' research centers on paligenosis, a cellular program he identified that allows mature cells to return to a regenerative state. His work explores how this process contributes to tissue repair but also increases cancer risk through the development of precancerous conditions like metaplasia. Using organoid models derived from patient cancer cells and genetic mouse strains, his lab investigates the molecular mechanisms of cellular plasticity in gastric biology, with implications for cancer prevention and treatment. His research integrates cell biology, metabolism, and translational approaches to understand how cells adapt to stressors. Analysis of Dr. Mills' recent publications reveals a strong focus on the molecular mechanisms of paligenosis and its role in gastric metaplasia and cancer development. His work spans basic cell biology investigations of cellular reprogramming to translational studies using patient-derived organoids. Key themes include the role of transcription factors like SOX9, metabolic regulation of cell fate decisions, and the identification of biomarkers for cancer progression. Dr. Mills has received several prestigious awards, including: Excellence in Research and Leadership Award from Baylor College of Medicine (2022) Top Reviewer for Gastroenterology from the American Gastroenterological Association (2022) Membership Induction to the Association of American Physicians (2022) Research Mentor Award from the AGA Institute Council (2022) Dr. Mills currently mentors several graduate students and postdoctoral researchers in the Mills Lab. His research is supported by multiple NIH grants totaling over $30 million, including R01 grants from NCI and NIDDK focused on mechanisms of paligenosis, metaplasia, and gastric cancer development. These grants support investigations into cellular reprogramming, stem cell differentiation, and therapeutic approaches for precancerous lesions. The Mills Lab maintains a collection of organoids derived from patient cancer cells and utilizes advanced techniques including single-cell RNA sequencing and spatial transcriptomics. The lab collaborates with clinicians at Baylor College of Medicine and across the Texas Medical Center to translate basic findings into clinical applications for personalized cancer treatment.