Biliary Tree Pathology Professors and Supervisors

Lindsay Alpertمشاهده پروفایل

دانشیار

University of ChicagoUnited States

Lindsay Alpert is an Associate Professor in the Department of Pathology at the University of Chicago's Pritzker School of Medicine. As a surgical pathologist specializing in gastrointestinal pathology, Dr. Alpert provides expert diagnostic services for neoplastic and non-neoplastic diseases of the gastrointestinal tract, biliary tree, and pancreas. Dr. Alpert received her MD from Columbia University College of Physicians and Surgeons in 2012. She completed her residency in Anatomic Pathology and fellowship in Gastrointestinal and Hepatic Pathology at the University of Chicago, finishing her fellowship in 2016 and residency in 2017. Dr. Alpert's research focuses on gastrointestinal pathology with particular expertise in inflammatory bowel disease, colorectal carcinoma, and the gut microbiome. Her work examines dysplasia patterns in IBD patients, histologic features of enteropathies, and the impact of therapeutic interventions on gastrointestinal tissues. She has made significant contributions to understanding the histologic spectrum of various gastrointestinal conditions and their clinical implications, with numerous publications in high-impact journals like Modern Pathology and Gastroenterology. Analysis of Dr. Alpert's recent publications reveals a strong focus on gastrointestinal pathology, particularly inflammatory bowel disease and colorectal neoplasia. Her work spans diagnostic pathology, molecular characterization of gastrointestinal tumors, and the impact of therapeutic interventions. Many studies examine dysplasia patterns in IBD patients across different age groups and presentations, while others investigate rare gastrointestinal conditions and their histologic features. Her research often bridges basic science with clinical applications, examining how dietary and pharmacological factors influence gastrointestinal pathology. Dr. Alpert actively collaborates with numerous researchers and clinicians at the University of Chicago and beyond, contributing to multidisciplinary studies that bridge pathology with clinical gastroenterology and oncology. Her network includes prominent colleagues such as John Hart, Namrata Setia, and Shu-Yuan Xiao. Dr. Alpert maintains an active research laboratory focused on gastrointestinal pathology, where she mentors trainees and collaborates with colleagues on various research projects examining the histopathology of gastrointestinal diseases. Her team works closely with clinicians to translate pathological findings into improved diagnostic criteria and patient care, particularly for complex cases involving inflammatory bowel disease and gastrointestinal neoplasia.

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Luke Boulterمشاهده پروفایل

پژوهشگر

University of EdinburghUnited Kingdom

Luke Boulter is a Reader and Cancer Research UK Fellow at the University of Edinburgh , affiliated with the Institute of Genetics and Cancer and the MRC Human Genetics Unit . His research focuses on Wnt signaling in liver tissue repair and cancer progression. BSc (Hons) in Molecular Cell Biology – University of York (2004) PhD – University of Edinburgh (2011) Luke’s lab investigates how Wnt signaling regulates liver regeneration, bile duct development, and cholangiocarcinoma. Key themes include: Canonical and non-canonical Wnt pathway dynamics Epithelial-mesenchymal interactions in disease Therapeutic targeting of signaling networks His recent publications highlight work on: Biliary tree patterning (2024) TGFβ-ECM-integrin axis in polycystic liver disease (2023) CRISPR-based genetic heterogeneity analysis in cholangiocarcinoma (2022) Scientific awards include: Cancer Research UK Fellowship Leverhulme Trust Early Career Fellowship Current projects funded by MRC, CRUK, UKRI, and Chief Scientist Office focus on repatterning cystic environments, targeting tumor-initiating cells, and pharmacological Wnt modulation.

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Nasreen Mahomedمشاهده پروفایل

دانشیار

University of WitwatersrandSouth Africa

Associate Professor Nasreen Mahomed is a faculty member in the Department of Radiology at the University of the Witwatersrand, based at Chris Hani Baragwanath Hospital in Johannesburg. She holds an MBBCh degree from the University of the Witwatersrand and maintains an active clinical and research profile in diagnostic radiology. Her educational background includes: MBBCh, University of the Witwatersrand Dr. Mahomed's research spans pediatric radiology, diagnostic imaging, and radiation safety, with emphasis on childhood tuberculosis, lung infections, and AI applications in radiology. Her work addresses radiation dose optimization in pediatric CT and interventional procedures while advancing computer-aided diagnosis systems for pneumonia in resource-limited settings. Analysis of her publication record reveals consistent focus on rare pediatric tumors, congenital anomalies, and diagnostic protocol refinement. Her contributions to the WHO Chest Radiography project demonstrate commitment to global health standardization, particularly in pneumonia diagnosis for children. While specific advising roles and grant details are not documented in available sources, her extensive publication output across South African and international journals indicates significant research leadership in radiological practice improvement.

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Alvin Curtis Linمشاهده پروفایل

پژوهشگر

Paracelsus Private Medical UniversityAustria

Alvin Curtis Lin is a researcher at the Institute of Anatomy and Cell Biology of Paracelsus Medical University. His work spans bioengineering, biomechanics, and clinical medicine, with a focus on soft tissue analysis and surgical techniques. Recent publications highlight his contributions to 3D-printed medical devices and tendon repair methodologies. Primary Affiliation: Institute of Anatomy and Cell Biology, Paracelsus Medical University Key Research Areas: Bioengineering, Biomechanics, Hepatology, Surgical Techniques Research interests include biomechanical modeling, finite element analysis, and the application of engineering principles to medical challenges. His 2024 work on 3D-printed clamping systems and tendon repair techniques demonstrates interdisciplinary innovation. Recent publications emphasize bioengineering solutions (10 in 2024), including peer-reviewed original articles and reviews. Key trends involve soft tissue testing parameters and stress concentration analysis in surgical contexts. Advising & Collaborations : Currently lacks explicit student mentorship details. Frequent collaborations with Hammer, N., and other surgical researchers across disciplines. Labs & Teams : Active within the Institute of Anatomy and Cell Biology, contributing to biomechanical and clinical research projects.

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Nicholas McDonaldمشاهده پروفایل

استادیار

Temple UniversityUnited States

Nicholas McDonald, MD serves as an Assistant Professor of Clinical Medicine at Lewis Katz School of Medicine at Temple University, specializing in Gastroenterology with expertise in advanced endoscopic procedures. His clinical practice is based at the Temple Digestive Disease Center in Philadelphia. Education: MD from University of Minnesota School of Medicine, Minneapolis, MN Fellowship in Advanced Endoscopy at Thomas Jefferson University, Philadelphia, PA Fellowship in Gastroenterology at University of Minnesota, Minneapolis, MN Residency in Internal Medicine at Mayo Clinic, Rochester, MN Dr. McDonald's research focuses on third space endoscopy, endoscopic innovation, and interventional ultrasound techniques. His work bridges clinical practice with technological advancement in endoscopic procedures, particularly in complex biliary and pancreatic interventions. He has published extensively on endoscopic mucosal resection, submucosal dissection, and novel approaches to gastrointestinal tract management. His recent publications demonstrate a strong emphasis on improving safety and efficacy of endoscopic procedures, with particular attention to early-career advanced endoscopists' performance and innovative techniques for challenging anatomical situations including post-surgical anatomy. Awards and Honors: ACG 2022 Outstanding Poster Presenter Award Social Media Acumen Award, American College of Gastroenterology SCOPY Award, 2023 Attitude, Commitment and Excellence Award (A.C.E.) – Mayo Clinic, 2019 Presidential Poster at American College of Gastroenterology 2018 Dr. McDonald maintains active professional memberships in the American Society for Gastrointestinal Endoscopy and the American College of Gastroenterology. His clinical work integrates cutting-edge endoscopic techniques with comprehensive patient care, focusing on complex gastrointestinal conditions requiring advanced interventional approaches.

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Anabel Martinez Lyonsمشاهده پروفایل

پژوهشگر

University of EdinburghUnited Kingdom

Dr. Anabel Martinez Lyons is a Research Associate affiliated with the Mary Bruck Research Institutes in Bioengineering at the University of Edinburgh. Her research focuses on tissue regeneration, hepatic disease modeling, and advanced organotypic systems. Key areas include: Bile duct morphogenesis and regeneration mechanisms Development of microfluidic liver-on-chip platforms for MASLD-MASH disease modeling Collagen-integrin signaling pathways in tissue repair Patient-derived tissue models for precision oncology Her recent publications demonstrate a consistent focus on translational approaches to liver regeneration and disease pathology, employing cutting-edge techniques like electric cell-substrate impedance sensing and 3D organotypic modeling.

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Hanna Rafaela Ferreira Dalla Priaمشاهده پروفایل

استادیار بالینی

University of UtahUnited States

Hanna Rafaela Ferreira Dalla Pria, MD, serves as a Clinical Assistant Professor in the Department of Radiology & Imaging Sciences at The University of Texas MD Anderson Cancer Center. Board-certified by the Brazilian Board of Radiology and Educational Commission for Foreign Medical Graduates, she specializes in diagnostic radiology with subspecialty expertise in thoracic and abdominal imaging. Her educational background includes: MD from Faculdade de Medicina Sao Jose do Rio Preto Medicine Internship at Faculdade de Medicina Sao Jose do Rio Preto Diagnostic Radiology Residency at Universidade Federal de Sao Paula Escola Paulista de Medicina Thoracic Imaging Fellowship at The University of Texas MD Anderson Cancer Center Dr. Dalla Pria's research focuses on diagnostic challenges in radiology, particularly interpretative pitfalls in oncologic imaging. Her work addresses critical areas including neuroendocrine neoplasms, pancreatic adenocarcinoma resectability assessment, sclerosing cholangitis diagnosis, and lung cancer screening protocols. She develops practical imaging guides that enhance diagnostic accuracy in complex clinical scenarios. Analysis of her 15 publications (2018-2025) reveals consistent emphasis on review articles that systematize radiological knowledge. Key trends include radiomics applications in cancer therapy assessment, anatomical variant recognition (e.g., accessory liver lobes), and infection imaging in immunocompromised hosts. Her scholarship bridges clinical practice with advanced imaging techniques, prioritizing actionable insights for radiologists. No scientific awards were documented in the provided materials. Information regarding student advising, research grants, and laboratory teams was not specified in the available documentation. Her current role involves clinical teaching within MD Anderson's Radiology & Imaging Sciences department, contributing to resident and fellow education through practical case discussions and scholarly publications.

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Ahsun Riazمشاهده پروفایل

دانشیار

Northwestern UniversityUnited States

Ahsun Riaz is an Associate Professor in Radiology (Vascular and Interventional Radiology) at Northwestern University's Feinberg School of Medicine. He specializes in hepatobiliary interventions, thoracic oncology, splenic disorders, and lymphatic diseases. His academic roles include leadership in clinical trials, editorial board memberships, and mentorship. Education and Training: MBBS: King Edward Medical College, Pakistan (2006) Internship: Northwestern University McGaw Medical Center, General Surgery (2011) Residency: Northwestern University, Diagnostic Radiology (2015) Fellowship: Northwestern University, Interventional Radiology (2016) Research Focus: Dr. Riaz’s work spans biliary interventions, radioembolization therapies, and interventional oncology. He investigates novel techniques for managing acute cholecystitis, liver metastases, and cholangiocarcinoma. His research emphasizes patient safety, procedural innovation, and multidisciplinary care. Clinical Trials: He leads trials such as "The Role of PET/MR Imaging in Yttrium-90 Radioembolization Treatment Planning" , focusing on improving liver malignancy treatment efficacy and safety. Awards and Recognition: Radiology Research Mentor of the Year (2024, 2025) KEMCAANA Young Investigator Award (2015) Multiple SIR Foundation Research Awards (2009, 2015) Professional Activities: Editorial roles at Journal of Vascular and Interventional Radiology , BMC Cancer , and others Member of SIR Comparative Effectiveness Research Committee Guest Editor for Seminars in Interventional Radiology and Digestive Diseases and Interventions Laboratory and Teams: His research group focuses on interventional radiology innovations, including cholangioscopy, biliary lithotripsy, and personalized radiation dosimetry for liver cancers.

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Giacomo Lanzoniمشاهده پروفایل

استادیار

University of MiamiUnited States

Giacomo Lanzoni is an Assistant Professor in the Department of Biochemistry and Molecular Biology, specializing in Regenerative Medicine strategies for Type 1 Diabetes (T1D). His research focuses on regenerating and protecting pancreatic islet ß cells, which are destroyed in T1D patients due to autoimmune attacks. PhD in Human Development and Reproduction (Stem Cells Biotechnology), University of Bologna (2010) MS in Biotechnology in Medicine, University of Bologna (2006) BS in Biotechnologies, University of Bologna (2004) Dr. Lanzoni’s work bridges Stem Cell Research and Biotechnology to address T1D pathophysiology. He investigates immunomodulatory approaches to protect ß cells, while exploring cell transplantation techniques and metabolic biomarkers. Recent publications highlight advancements in MSC-based therapies for graft-versus-host disease, ß cell regeneration via immunomodulatory microgels, and the role of Vitamin D in T1D severity. His studies also address auditory complications in T1D and comparative stem cell biology in pigs/humans. Marc S. Goodman Outstanding Young Scientist award (2014), Diabetes Research Institute Foundation Proni Quinto and Caravita Zita award, University of Bologna Cancer Research Center

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Geoffrey McCaughanمشاهده پروفایل

استاد

University of SydneyAustralia

Professor Geoffrey McCaughan holds the W Morrow Professorship in Medicine at the University of Sydney's Central Clinical School. He is affiliated with the Centenary Institute of Cancer Medicine & Cell Biology and collaborates with institutions like the National Health and Medical Research Council (NHMRC). His research focuses on liver transplantation tolerance mechanisms, hepatocellular carcinoma (HCC), immune tolerance pathways, and translational applications of normothermic machine perfusion. He has contributed to studies on biliary injury prevention, HCC recurrence, and the impact of geographic access on transplant outcomes. His educational background and prior roles are not explicitly detailed in the text, but his work spans clinical and experimental hepatology, with expertise in viral hepatitis (especially HCV), liver immunology, and organ preservation technologies. Key research approaches include animal models, molecular proteomics, and clinical trial designs. McCaughan leads investigations into vascular and metabolic factors in liver disease, such as the role of sphingosine kinase in tumor growth and the influence of DPP4/DPP9 enzymes on fibrosis and cancer progression. He actively participates in national and international collaborations, including the INTERLIVER study on molecular rejection diagnosis and the APRICA trial on palliative care integration for HCC patients. In advising, he supervises Mingchang ZHANG's research on liver cancer and hepatitis. His work emphasizes improving graft quality, addressing immunosuppression challenges, and optimizing transplant criteria. He is also involved in translational research to expand donor liver utilization through split-liver techniques and ex vivo perfusion systems. Collaborations include teams at the Centenary Institute and the National Liver Transplant Service.

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Robert C. Huebertمشاهده پروفایل

استاد

Mayo Clinic College of Medicine and ScienceUnited States

Robert C. Huebert, M.D., is a Professor of Medicine and Associate Professor of Regenerative Medicine at Mayo Clinic, where he serves as a Consultant in the Division of Gastroenterology and Hepatology and Director of the Transplant Research Center since 2023. His work bridges clinical hepatology and cutting-edge regenerative research, focusing on cholangiopathies and liver fibrosis. Ph.D. in Biochemistry and Molecular Biology, University of Minnesota Duluth M.D., University of Minnesota Medical School, Twin Cities Residency and Fellowship training at Mayo Clinic, including Advanced Fellowship in Transplant Hepatology Board Certified in Gastroenterology and Transplant Hepatology Dr. Huebert's research centers on liver regenerative medicine, particularly the molecular and epigenetic mechanisms driving biliary development, fibrosis, and repair. His lab pioneered methods to derive cholangiocytes from induced pluripotent stem cells (iPSCs), enabling patient-specific disease modeling and drug testing. This technology supports the Liver Biobank, a biorepository of patient-derived iPSCs developed in collaboration with the Mayo Clinic Regenerative Medicine Biotrust. His long-term goal is to develop cell-based therapies for cholangiopathies, having demonstrated in vivo engraftment of stem cell-derived cholangiocytes. His recent publications highlight advances in cholangiocyte biology, liver fibrosis mechanisms, bioengineered livers, and iPSC modeling. Themes include epigenetic regulation in primary sclerosing cholangitis, metabolic control of fibrogenesis via hepatic stellate cells, and microencapsulation strategies for cell therapy. These works reflect a strong translational trajectory toward regenerative therapeutics. Scientific awards and recognitions include: Gilead Sciences Research Scholars Award in Liver Disease (2016) NIH K08 Career Development Award (2013) Postdoctoral Scholar Award, Regenerative Medicine Minnesota (2015) Young Investigator of the Year, Hartz Foundation (2009) Research Pipeline K2R Transition Award, Mayo Clinic (2018) Multiple awards from NIH Loan Repayment Program Dr. Huebert leads NIH-funded projects on cholestatic fibrogenesis and epigenetic regulation in liver disease. He mentors trainees and collaborates widely across regenerative medicine, gastroenterology, and transplantation. He is actively involved in professional societies including AASLD and EASL, and serves on editorial and leadership committees at Mayo Clinic, including the Institutional Animal Care and Use Committee and the Center for Individualized Medicine. His laboratory, the Biliary Epigenetics and Regenerative Medicine Laboratory, is a hub for innovation in liver disease modeling and therapy development, supported by core facilities and collaborative networks at Mayo Clinic.

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Claire O’Learyمشاهده پروفایل

استادیار

University of Wisconsin-MadisonUnited States

Claire O’Leary is an Assistant Professor in the Department of Pediatrics at the University of Wisconsin–Madison, School of Medicine and Public Health. She leads the O’Leary Research Group, focusing on epithelial-immune-microbiome interactions in gastrointestinal and biliary tissues. Her lab is based at the Clinical Science Center in Madison, WI, and she is affiliated with the University of Wisconsin Carbone Cancer Center and Immunology at Wisconsin. Position: Assistant Professor Division: Allergy, Immunology, and Rheumatology Location: H6/565 Clinical Science Center, 600 Highland Ave, Madison, WI 53706 Dr. O’Leary’s research centers on how tuft cells in the epithelial barrier regulate immune responses in harsh environments such as the gut and biliary tract. Her work explores how tissues limit inflammation despite constant exposure to acids, enzymes, and microbiome-derived ligands. She investigates the role of bile acids as signaling molecules and how they, along with microbial metabolites, influence immune cell behavior. Her studies integrate mucosal immunology, epithelial biology, and microbiome science to understand tissue homeostasis and inflammation. Her recent publications, including in Science Immunology (2022), highlight her contributions to understanding tuft cell function in antibacterial defense and immune regulation. The research reveals tissue-specific roles of tuft cells in the small intestine, airways, and biliary tree, emphasizing their capacity to produce effector molecules like IL-25 and coordinate protective responses. Research Focus: Tuft cell biology, epithelial-immune crosstalk, microbiome-host interactions, bile acid signaling, mucosal immunology Key Models: Mouse models of inflammation, fluorescent imaging, microbiome manipulation Dr. O’Leary has received competitive funding, including support from the Research Forward initiative, which promotes innovative research at UW–Madison. She is also associated with the Gerard B. Odell Research Award, recognizing excellence in basic or translational pediatric research among early-career faculty. She actively mentors graduate students and is a trainer in the Cellular and Molecular Pathology (CMP), Cellular and Molecular Biology (CMB), and Microbiology Doctoral Training Programs. The O’Leary lab is currently recruiting graduate students and a T32-supported postdoctoral fellow, indicating active research expansion and training opportunities. The O’Leary Research Group is part of a vibrant research ecosystem within the Department of Pediatrics, which ranks among the top 20 NIH-funded pediatric departments nationally. Her work contributes to broader efforts in understanding inflammatory diseases and developing novel therapeutic strategies targeting epithelial-immune communication.

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Mario Strazzaboscoمشاهده پروفایل

استاد

Max Planck Institute of Molecular Cell Biology and GeneticsGermany

Mario Strazzabosco, MD, PhD, is a Professor of Medicine in the Department of Internal Medicine (Digestive Diseases) at Yale School of Medicine. He serves as Clinical Program Leader of the Liver Cancer Program at Yale Cancer Center, Co-Director of the Yale Liver Center, and Director of the Smilow Liver Cancer Program. Previously, he held leadership positions at the University of Milan, including Founding Chief of the Section of Digestive Diseases, Chair of the Department of Surgery and Translational Medicine, and Vice President of the School of Medicine. Dr. Strazzabosco's research focuses on the pathophysiology and therapy of cholangiopathies (diseases of the biliary tree), including Cystic Fibrosis cholangiopathy, polycystic liver disease, and Alagille syndrome. His laboratory investigates the role of biliary cells in liver repair and regeneration, as well as hepatocellular carcinoma therapy. His work aims to translate basic discoveries in liver cell biology into advanced patient care. Analysis of Dr. Strazzabosco's recent publications (2024-2025) reveals a strong focus on liver cancer diagnostics, treatment response assessment, and the molecular mechanisms underlying biliary diseases. His work spans clinical research on HCC staging systems and cost-effectiveness, molecular studies of cholangiocarcinoma metastasis, and investigations into the pathophysiology of primary sclerosing cholangitis. NIH funding recipient for liver disease research Active contributor to hepatology literature with multiple high-impact publications As Clinical Program Leader, Dr. Strazzabosco oversees a multidisciplinary team that provides coordinated care for liver cancer patients. His clinical approach emphasizes personalized treatment that preserves liver function while addressing cancer, with collaboration across medical oncology, interventional radiology, surgical oncology, hepatology, and transplantation surgery specialties. His Hepar Lab serves as the research hub for translating basic science discoveries into clinical applications for liver disease patients.

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