جستجوی استاد راهنمای دانشگاهی

• Immunology
• Virology
• Inflammation
• +۵ مورد دیگر

Santiago F. González is a Group Leader at the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland, and an extraordinary professor at the University of Italian Switzerland (USI). He earned dual PhDs in microbiology (University of Santiago de Compostela, Spain) and immunology (University of Copenhagen, Denmark), followed by postdoctoral work (2007–2011) at Harvard Medical School's Immune Disease Institute under Michael Carroll. PhD in Microbiology, University of Santiago de Compostela PhD in Immunology, University of Copenhagen His research focuses on immune system dynamics during respiratory viral infections, vaccination, and cancer metastasis. Key areas include influenza recognition , lymph node inflammation , and immune cell behavior in vivo. He pioneered studies on C-type lectin receptors (e.g., SIGN-R1) in viral immunity and epigenetic modulators for inflammation. Recent publications highlight his work in epigenetic drug development , nanovaccines , and computational tools for immune cell tracking. His group uses two-photon intravital microscopy and spatial-temporal modeling to dissect immune responses. Scientific awards include three EU Marie Curie Fellowships (2004–2013), enabling his transition to independent research. His collaborations span Harvard, USI, and European institutions, with grants from the EU and Swiss research bodies. His lab at IRB, established via the 2013 Marie Curie Career Integration Grant , develops novel imaging approaches and therapeutic strategies for infectious and immune-mediated diseases.

Pierre Maechlerمشاهده پروفایل

استاد

• Mitochondrial metabolism
• Beta-cell function
• Diabetes research
• +۵ مورد دیگر

Pierre Maechler is a Professor at the University of Geneva's Faculty of Medicine in the Department of Cell Physiology and Metabolism. His research focuses on mitochondrial metabolism in pancreatic beta cells and its critical role in diabetes pathogenesis, with particular emphasis on glutamate dehydrogenase function and regulation. His laboratory investigates the molecular mechanisms of insulin secretion and beta-cell failure in Type 2 diabetes. Maechler's research interests span mitochondrial metabolism, energy homeostasis, and the molecular pathways linking nutrient sensing to insulin secretion. His work has established crucial connections between glutamate metabolism, beta-cell function, and diabetes development. He investigates how metabolic stressors like glucotoxicity and lipotoxicity impair beta-cell function through mitochondrial dysfunction. His research has expanded to include the role of glutamate dehydrogenase in multiple organs including brain, liver, and muscle, revealing systemic metabolic implications. Analysis of Maechler's publication record shows a sustained focus on beta-cell metabolism with evolving scope. Early work established fundamental mechanisms of glutamate signaling in insulin secretion, while recent publications demonstrate expansion into multi-organ metabolic regulation. His research has identified novel biomarkers for beta-cell mass, explored therapeutic targets for diabetes, and revealed unexpected roles for glutamate dehydrogenase in diverse physiological processes from muscle regeneration to brain function. The consistent thread through his work is understanding how mitochondrial metabolism governs cellular and systemic energy homeostasis. Professor Maechler has mentored numerous PhD students and postdoctoral fellows who have gone on to publish significant work in diabetes research. His laboratory collaborates extensively with clinical researchers to translate basic findings into potential therapeutic approaches for diabetes. Funding for his work likely comes from Swiss National Science Foundation and other European research agencies, supporting investigations into metabolic diseases. Maechler leads the Mitochondria and Energy Metabolism research group at the University of Geneva. His team employs a multidisciplinary approach combining molecular biology, metabolomics, and physiology to investigate metabolic regulation in health and disease. The laboratory maintains strong connections with clinical diabetes researchers, facilitating translational applications of their findings. Current work focuses on identifying novel therapeutic targets for preserving beta-cell function in diabetes.

Roderick Limمشاهده پروفایل

دانشیار

• Nuclear Pore Complex Transport
• Mechanobiology of Cells and Tissues
• Biomimetic Molecular Transport Systems
• +۵ مورد دیگر

Prof. Dr. Roderick Lim is an Associate Professor at the Biozentrum, University of Basel , where he leads a research group since 2014. His work bridges biophysics, nanotechnology, and molecular biology , focusing on the nuclear pore complex (NPC) and mechanobiology of cells . He develops biomimetic systems for selective molecular transport and ARTIDIS , a nanomechanical tissue diagnostic platform commercialized for breast cancer prognosis . Education : BSc (UNC Chapel Hill), PhD (NUS/IMRE Singapore), Postdoc (Swiss Nanoscience Institute) Positions : Argovia Professor (2014–present), Tenure Track Asst. Prof. (2009–2013), Postdoc (2004–2008) His research on NPC transport selectivity reveals how karyopherins modulate the FG Nup barrier via multivalent interactions, with implications for viral entry and Alzheimer’s disease . His ARTIDIS platform uses atomic force microscopy to detect cancer via tissue softness, linking hypoxia to metastasis . Recent 2025 publications explore bacterial nanoharpoon defense mechanisms and DNA origami-based NPC mimics . Scientific Awards : Pierre-Gilles de Gennes Prize (2008), A*STAR Fellowship (2004) Collaborations : NCCR Molecular Systems Engineering, NanoTera, KTI He mentors PhD students in institutions across Switzerland, Singapore, Sweden, and the UK , with alumni working on polymersome delivery, mechanotransduction, and pathogen transport . His lab pioneered high-speed atomic force microscopy for real-time NPC dynamics and plasmonic nanopores for synthetic biology applications.

Monticelli Silviaمشاهده پروفایل

استاد پژوهش

• Molecular Immunology
• T lymphocyte biology
• Mast cell biology
• +۴ مورد دیگر

Silvia Monticelli is a Group Leader in Molecular Immunology at the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland. She earned her Ph.D. from the University of Milan and has held research positions at San Raffaele Scientific Institute, King’s College London, and Harvard Medical School. Her research focuses on transcriptional and post-transcriptional regulation of immune responses, particularly in T lymphocytes and mast cells. Education: Ph.D. – University of Milan, Italy Postdoctoral training – San Raffaele Scientific Institute, Milan Research training – Randall Institute, King’s College London Research training – Center for Blood Research, Harvard Medical School Research Interests: Silvia Monticelli’s lab investigates the molecular mechanisms that control gene expression in immune cells. Her work spans epigenetic regulation , microRNA function , transcription factor networks , and RNA methylation in T cells and mast cells. A central theme is understanding how these mechanisms shape immune cell identity and function in health and disease. Publication Trends: Her recent publications (2020–2024) reflect a strong emphasis on RNA biology , epigenetic control , and immune regulation . She has contributed to high-impact journals such as Nature , Nature Immunology , and Science Advances , with work ranging from microRNA-mediated control of T cell activation to epigenetic regulation in mast cells and cancer immunity. Scientific Recognition: While no formal awards are listed, her work has been highlighted by editorial commentary and co-corresponding authorships in high-impact journals, indicating recognition within the immunology community. Labs & Affiliations: She leads a research group at the IRB in Bellinzona, focusing on immune cell regulation at the molecular level. Her lab is part of a broader European research network and collaborates with institutions like Harvard and the University of Milan.

Matteo Dal Peraroمشاهده پروفایل

دانشیار

• Computational Biophysics
• Molecular Modeling
• Structural Biology
• +۵ مورد دیگر

Matteo Dal Peraro is an Associate Professor at École polytechnique fédérale de Lausanne (EPFL) in the School of Life Sciences, where he leads the Laboratory for Biomolecular Modeling (LBM) within the Interfaculty Institute of Bioengineering (IBI). He also holds significant administrative roles as Head of IBI-SV Administration and Co-Director of IBI-STI Administration, demonstrating his leadership across both the School of Life Sciences and School of Engineering. His research bridges computational approaches with experimental validation to understand complex biological systems at multiple scales. His educational background includes a B.S. and M.S. in Physics from the University of Padua (2000), followed by a Ph.D. in Biophysics from the International School for Advanced Studies (SISSA) in Trieste (2004). He then completed postdoctoral training at the University of Pennsylvania under Professor M. L. Klein before joining EPFL as a Tenure Track Assistant Professor in late 2007. Dal Peraro's research focuses on computational biophysics and multiscale modeling of biological systems, with particular emphasis on membrane-protein interactions, nanopore sensing technologies, and structural biology. His work spans fundamental molecular mechanisms to applied educational technologies, demonstrating a commitment to both scientific discovery and knowledge dissemination. He has made significant contributions to understanding protein-membrane interactions, antibiotic resistance mechanisms, mitochondrial disorders, and viral pathogenesis through advanced computational approaches. His publication record shows a strong trend toward integrating augmented and virtual reality technologies with molecular modeling, exemplified by his development of the moleculARweb platform for chemistry and structural biology education. His research spans computational methods development, structural characterization of biomolecules, membrane biophysics, and applications to medically relevant problems including antibiotic resistance and neurodegenerative disorders. This interdisciplinary approach connects fundamental biophysical principles with practical applications in medicine and education. Dal Peraro has mentored numerous doctoral students through EPFL's PhD programs, particularly in Computational and Quantitative Biology. His leadership extends to serving on PhD program committees and directing research groups focused on computational molecular biology. He has established collaborations across multiple disciplines, facilitating integrative approaches to complex biological problems. He leads the Laboratory for Biomolecular Modeling (LBM), which develops and applies computational methods to study biological systems at multiple scales. The lab bridges molecular simulations with experimental validation, creating a synergistic approach to understanding complex biological phenomena. Dal Peraro's team has made significant contributions to membrane biophysics, protein folding, and the development of educational technologies that make structural biology accessible through augmented reality platforms.

Patrick Aebischerمشاهده پروفایل

استاد

• Neuroscience
• Neurodegenerative Diseases
• Gene Therapy
• +۳ مورد دیگر

Patrick Aebischer is an Honorary Professor at EPFL, where he previously served as President from 2000 to 2016. He holds a medical degree from the University of Geneva (1980) and a PhD in Neuroscience from the University of Fribourg (1983). Before his tenure at EPFL, he held academic roles at Brown University (1984–1992) and the University Hospital of Lausanne (CHUV). His research focuses on neurodegenerative diseases, particularly through cell therapy and gene transfer approaches. Education : - Medicine (1980), University of Geneva - Neuroscience (1983), University of Fribourg Research Interests : Dr. Aebischer's work addresses neurodegenerative diseases such as Alzheimer's and Parkinson's. His lab develops therapies targeting amyloid-beta, tau pathology, and α-synuclein, using gene therapy and cell-based approaches. Recent studies include cellular implants for passive immunization and mitochondrial regulation via Urolithin A. Publications : His recent work highlights advancements in gene therapy for deafness, ALS modeling on microchips, and mechanisms linking aging to neurodegeneration. Over 150 publications span topics like viral vector applications and neuroenergetics. Affiliations & Roles : - Board member: Lonza, Logitech, Nestlé - Chair: Novartis Venture Fund Advisory Board - Founder: Three biotechnology startups Labs & Teams : His lab at EPFL focuses on translating research into therapies, collaborating with industry partners to advance clinical applications.

Molinari Maurizioمشاهده پروفایل

پژوهشگر

• Protein Folding
• Proteostasis
• Endoplasmic Reticulum Quality Control
• +۴ مورد دیگر

Maurizio Molinari is a Group Leader at the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland, since October 2000. He earned his PhD in Biochemistry from ETH-Zurich in 1995 and conducted postdoctoral research at the University of Padua and ETH-Zurich. His work focuses on protein folding, quality control, and degradation mechanisms within the endoplasmic reticulum (ER), with implications for rare diseases and Alzheimer’s pathology. Affiliation: IRB Bellinzona, Adjunct Professor at EPFL since 2008 Education: PhD in Biochemistry (ETH-Zurich, 1995) Dr. Molinari’s research explores the ER-phagy pathway , proteostasis , and lysosomal degradation as failsafe mechanisms during ER stress. His studies link these processes to neurodegenerative diseases , myelin maintenance , and rare genetic disorders . Recent publications highlight his contributions to allosteric enzyme modulation , organelle fragmentation , and computational tools for autophagy quantification . He received the Friedrich-Miescher Award in 2006 for his work in molecular biology. Scientific Networks: European Research Council (ERC), Rare Diseases Platform (Switzerland) Leadership Roles: Advisory Board, Centro Malattie Rare della Svizzera italiana

Stephan Grzesiekمشاهده پروفایل

استاد

• Structural Biology
• Nuclear Magnetic Resonance (NMR) Spectroscopy
• Protein Dynamics
• +۷ مورد دیگر

Stephan Grzesiek is a Professor of Biological NMR Spectroscopy at the Biozentrum, University of Basel, Switzerland. He leads a research group focused on the structural and dynamic characterization of biomolecules using nuclear magnetic resonance (NMR) spectroscopy. His work bridges physics, chemistry, and biology, with a strong emphasis on disease-relevant proteins such as GPCRs, kinases, and HIV-related receptors. Research Interests: His research centers on understanding biomolecular function through atomic-level insights into protein structure, dynamics, and interactions. He focuses on G-protein coupled receptors (e.g., β1-adrenergic receptor, CCR5), tyrosine kinases (e.g., Abl kinase), and membrane-associated signaling complexes. His group develops advanced NMR methodologies for studying unfolded states, hydrogen bonding, and allosteric regulation. Recent Research Trends: Analysis of his recent publications (2021–2025) reveals a strong focus on GPCR-arrestin interactions, kinase regulation mechanisms, and the structural basis of drug action. His work employs high-resolution NMR, often combined with Cryo-EM and biochemical assays, to dissect conformational dynamics, allosteric networks, and signal transduction pathways. Key themes include biased agonism, cholesterol modulation, and the molecular basis of drug inhibition in cancer and infectious disease. Scientific Awards & Recognitions: Laukien Prize (ENC) Fellow, International Society of Magnetic Resonance Honorary Member, National Magnetic Resonance Society of India Chair, Gordon Conference on Computational Aspects of Biomolecular NMR Member, Swiss National Research Council VP, International Society of Magnetic Resonance Advising and Grants: While specific students are not listed, his frequent co-authorship with junior researchers (e.g., Iva Petrovic, Luca Abiko, Sanjana Desai) suggests active mentorship. His research is likely supported by major Swiss and international grants, given the scale and impact of his work. He has led long-term projects on NMR method development and structural biology of signaling proteins. Labs and Teams: He leads a research group at the Biozentrum, University of Basel, integrating NMR spectroscopy, protein engineering, and biophysical analysis. His team collaborates widely with structural biologists and biochemists, contributing to high-impact studies on GPCRs and kinase regulation.

• Immunology
• Infection and Immunity
• Antigen Trafficking
• +۱۲ مورد دیگر

Santiago González F. is an Extraordinary Professor at the Università della Svizzera italiana (USI), affiliated with the Faculty of Biomedical Sciences and the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland. He leads the Infection and Immunity research group, focusing on immune responses to infections and cancer. His work integrates molecular immunology, intravital imaging, and nanotechnology to understand immune cell dynamics in vivo. PhD in Microbiology, University of Santiago de Compostela, Spain PhD in Immunology, University of Copenhagen, Denmark Postdoctoral Fellow, Harvard Medical School, USA (2007–2011) His research centers on the mechanisms of antigen trafficking, dendritic cell function, and immune regulation during influenza infection and tumor metastasis. He has made seminal contributions to understanding how SIGN-R1 mediates influenza recognition and how subcapsular sinus macrophages promote melanoma spread. His lab employs cutting-edge intravital microscopy and develops tools like CANCOL for immune cell tracking. The recent publications highlight a strong trend in immune cell dynamics, inflammation modeling, and vaccine development. His work spans from fundamental immunology to translational applications, including mRNA nanovaccines and immunomodulatory drugs. There is a consistent focus on lymph node biology, innate immunity, and real-time imaging of immune responses. Marie Curie Training Site Fellowship (2004) Marie Curie International Outgoing Fellowship (2008) Marie Curie Career Integration Grant (2013) Recognition by Faculty of 1000 Santiago González has secured significant research funding through the European Union’s Marie Curie program and ERC grants, enabling the establishment and growth of his independent research group at IRB. He mentors a multidisciplinary team of scientists and students, contributing to PhD and postdoctoral training programs. His collaborations include partnerships with Rockefeller University and national biotechnology centers. He directs the Infection and Immunity laboratory at IRB, which specializes in intravital imaging, immune cell tracking, and vaccine development. The lab has developed innovative platforms such as stealth mRNA nanovaccines and computational tools for image analysis. The team actively engages in technology transfer and participates in European research networks.

Horst Posthausمشاهده پروفایل

استاد

• Bacterial host-pathogen interactions
• Pore-forming toxins
• Clostridial infections
• +۵ مورد دیگر

Professor Horst Posthaus serves as Head of Research Group at the Department of Infectious Disease and Pathobiology within the Vetsuisse Faculty at the University of Bern. His research primarily focuses on bacterial host-pathogen interactions, with special emphasis on pore-forming toxins produced by Clostridia, particularly Clostridium perfringens β-toxin and its effects on host cells. His work bridges molecular mechanisms with clinical veterinary applications, utilizing in situ investigations in naturally diseased animals alongside cell- and molecular biology techniques. Posthaus's research interests center on understanding the molecular mechanisms of bacterial toxins, particularly how clostridial pore-forming toxins interact with host cells. His group has made significant contributions to identifying Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1 or CD31) as the cellular receptor for C. perfringens β-toxin. Through collaborations with structural biologists, his team determined the Cryo-EM structure of the transmembrane β-toxin pore, providing crucial insights into toxin function. His publication record demonstrates consistent contributions to understanding clostridial diseases in animals, with recent work expanding to include Mycoplasma pathogenesis, viral infections in livestock, and novel diagnostic approaches. His research follows a clear trajectory from basic molecular mechanisms toward practical applications for disease prevention and treatment strategies targeting bacterial toxins. Professor Posthaus leads an active research team including multiple PhD students and postdoctoral researchers, and serves as part of the COMPATH platform offering diagnostic and research support to other groups at the faculty. His work has significant implications for both veterinary and human medicine, as many clostridial diseases have zoonotic potential. Ana Carpio Espinosa (PhD student) Nil Hazal Ekenel (PhD student) Faezeh Farhoosh (PhD student) Jan Franzen (Resident/PhD) Alejandro Garcia Surio (PhD student) Basma Tarek (PhD student) Iva Cvitas (Post-Doc) Charlotte Griessen (Lab manager) Arunasalam Naguleswaran (Staff scientist) The Posthaus group maintains strong collaborations with researchers at the University of Bern and internationally, including work with Prof. Benoit Zuber at the Institute of Anatomy and Prof. M. Degiacomi at Durham University. Their research is supported by grants including the SNF-Sinergia project DISPERSE, focusing on developing novel strategies against bacterial toxins to prevent or treat clostridial diseases in animals and humans.

Benjamin MEYERمشاهده پروفایل

پژوهشگر

• Immunology
• Virology
• SARS-CoV-2 Research
• +۵ مورد دیگر

Benjamin MEYER serves as a Researcher at the University of Geneva, where he functions as a Scientific Collaborator within Arnaud Didierlaurent's research group. His work focuses on critical aspects of viral immunology with particular emphasis on SARS-CoV-2 and host immune responses. Dr. Meyer's primary research interests include: SARS-CoV-2 antibody dynamics and immune memory Viral load kinetics across variants Mucosal immune responses to infection and vaccination Serological assay development and validation Pediatric immune responses to viral pathogens Autoantibody production following viral infection His publication record reveals a consistent focus on translational immunology research, with significant contributions to understanding immune responses during the COVID-19 pandemic. Meyer's work spans high-impact journals including Nature, Nature Medicine, and PNAS, demonstrating methodological rigor in both clinical and laboratory approaches to viral immunology. Dr. Meyer actively mentors graduate researchers, as evidenced by his supervision of doctoral work on antibody-mediated cross-protection against influenza viruses. His collaborative network includes prominent researchers at the University of Geneva and international institutions, reflecting the interdisciplinary nature of modern virology research.

Jacqueline Hirschiمشاهده پروفایل

استاد

• Zinc Homeostasis
• Manganese Toxicity
• Metabolic Endotoxemia
• +۷ مورد دیگر

Jacqueline Hirschi is a Professor at ETH Zürich's Institute for Pharmaceutical Sciences, holding the Professorship for Pharmaceutical Chemistry. Her research focuses on metal ion homeostasis (zinc and manganese) and its implications in metabolic and neurological disorders. She employs in vitro and in vivo models, including Zip14 knockout mice, to study zinc's role in intestinal barrier function, insulin secretion, and hepatic glucose metabolism, as well as manganese's detoxification pathways and neurodegenerative associations. Key research areas include zinc-mediated metabolic endotoxemia, manganese-induced neuroinflammation, and the interplay between ZIP14 transporters and systemic inflammation. Her work bridges molecular mechanisms with translational insights into metabolic and neurodegenerative diseases. Dr. Hirschi's contributions address how disrupted metal transport impacts chronic inflammation, insulin resistance, adiposity, and neurodegeneration, with implications for therapeutic strategies targeting these pathways.

Nicole Jollerمشاهده پروفایل

استاد

• Immunology
• Host-Pathogen Interactions
• Regulatory T Cells
• +۳ مورد دیگر

Prof. Nicole Joller is a Professor for Immunology at the Department of Quantitative Biomedicine, University of Zurich, Switzerland. Her research focuses on understanding how prior infections influence long-term immune responses, particularly involving regulatory T cells (Tregs) and their role in autoimmunity and cancer susceptibility. She leads the Joller Lab, employing techniques like transcriptomics, flow cytometry, and animal models. Education: PhD in Immunology (ETH Zurich, 2008), Postdoctoral training at Harvard Medical School (2009–2014). Previous roles include SNSF/ERC Assistant Professor at UZH (2014–2021). Her lab investigates immune checkpoint receptors (e.g., TIGIT, LAG-3) and their impact on disease outcomes. Key collaborators include Prof. Vijay Kuchroo and Prof. Annette Oxenius. Research interests include Treg dynamics post-infection, cross-reactive immunity, and mechanisms of immune regulation. Her team studies how infections alter immune landscapes, with implications for vaccine design and autoimmune therapies. Recent work highlights innate-like memory T cell functions in heterologous diseases. Labs/Teams: Directs a multidisciplinary group including PhD students, postdocs, and bioinformaticians. Current funding supports projects on immune checkpoint agonists and Treg modulation in diseases.

Philipp Bergerمشاهده پروفایل

پژوهشگر

• Cellular Engineering
• Bioimaging
• Receptor Signaling
• +۴ مورد دیگر

Philipp Berger is a Scientist at the Paul Scherrer Institute (PSI) in Switzerland, affiliated with the Center for Life Sciences and leading the Laboratory for Multiscale Bioimaging . His position as a research group head involves developing advanced tools for cellular engineering and microscopy while investigating receptor signaling mechanisms in biomedical contexts. Research focuses on receptor trafficking and signaling pathways , particularly VEGFR-2 and GPCRs. Berger's group demonstrated how VEGF-A isoforms alter coreceptor recruitment and signaling (Ballmer-Hofer et al., 2011), identified TBC1D10 as a VEGFR2 signaling regulator (Xie et al., 2019), and pioneered split nanoluciferase assays to study time-resolved adapter protein recruitment for GPCRs (Romantini et al., 2021). Core expertise spans molecular engineering of cellular processes and quantitative microscopy. Recent publications (2021-2023) reveal diversification into diagnostic applications (polymer brush diagnostics, SARS-CoV-2 nanofluidic devices) and neurodegenerative disease mechanisms (Apolipoprotein E-amyloid interactions), while maintaining foundational work on receptor trafficking. The lab's signature tools—Squassh for image analysis and baculovirus systems for multigene delivery—underpin most studies. Scientific Awards: No awards mentioned in source materials Advising and Grants: Berger leads a research group with active publications indicating supervision of junior scientists, though specific students aren't listed. Extensive tool development and cross-disciplinary collaborations (e.g., nuclear medicine, virology) imply sustained grant funding, though specific grants aren't documented in the provided text. Labs and Teams: He directs the Laboratory for Multiscale Bioimaging at PSI. His team developed the MultiLabel/MultiPrime cre/LoxP-based multigene expression system (Kriz et al., 2010; Mansouri et al., 2016), Squassh image segmentation tools (Rizk et al., 2014, 2015), and split nanoluciferase GPCR assays (Spillmann et al., 2020; Romantini et al., 2021). All tools are publicly available via download packages with manuals.

Pedro HERRERAمشاهده پروفایل

استاد

• Endocrinology
• Diabetes Research
• Pancreatic Islet Biology
• +۳ مورد دیگر

Pedro HERRERA is a Full Professor at the University of Geneva, where he conducts significant research in pancreatic islet biology and diabetes. His academic position and extensive publication record indicate a prominent role in endocrinology research. His research focuses on several key areas within diabetes and islet cell biology: Cell reprogramming of pancreatic alpha cells into insulin-producing cells Mechanisms of insulin and glucagon secretion regulation Compensatory mechanisms following beta cell loss Islet transplantation and immunological aspects Molecular mechanisms of diabetes pathogenesis Translational applications for diabetes treatment Analysis of his recent publications reveals a strong emphasis on understanding pancreatic islet cell identity, function, and plasticity. His work consistently explores how pancreatic cells can be manipulated for therapeutic purposes, particularly through cell reprogramming approaches that could potentially treat diabetes without requiring external insulin administration. The research demonstrates sophisticated understanding of cellular mechanisms and shows promise for future diabetes therapies. Dr. HERRERA's work bridges fundamental science with clinical applications, making significant contributions to both theoretical understanding of islet cell biology and practical approaches to diabetes treatment. His research group appears to include laboratory technicians, doctoral candidates, and other researchers working collaboratively on various aspects of pancreatic islet biology.