جستجوی استاد راهنمای دانشگاهی

Xin Jiangمشاهده پروفایل

پژوهشگر ارشد

• Structural Biology
• Biochemistry
• Membrane Protein Mechanisms
• +۳ مورد دیگر

Dr. Xin Jiang is a Senior Research Fellow at the School of Biotech & Biomolecular Science, University of New South Wales (UNSW), specializing in structural biology and biochemistry. He investigates membrane protein mechanisms and their therapeutic applications, particularly focusing on malaria and cancer metabolism. PhD in 2017 from Tsinghua University under Prof. Yigong Shi Postdoctoral training at Princeton University (2018) with Prof. Nieng Yan Joined UNSW in 2019 Research interests include: Decoding Plasmodium membrane proteins for antimalarial drug development Exploring lipid/cholesterol biogenesis mechanisms in collaboration with BABS senior lipid researchers Publications highlight expertise in glucose/lactate transporters, the Warburg effect, and transporter inhibition strategies. His work spans structural analysis of the Plasmodium falciparum hexose transporter, monocarboxylate transporters, and dual inhibitors targeting malaria and cancer metabolism.

• Alzheimer's Disease
• Vascular Biology
• Endothelial Cell Biology
• +۶ مورد دیگر

Dr. Ka Ka Ting serves as an Adjunct Lecturer in the Department of Medical Sciences at the University of Sydney's Faculty of Medicine and Health, where she is an active member of the Brain and Mind Centre. Her research bridges vascular biology and neurological disorders, with a primary focus on endothelial dysfunction mechanisms in Alzheimer's disease, cancer, and diabetic complications. Her work centers on blood-brain barrier integrity, cellular senescence, and microRNA-based therapeutics, particularly examining VE-cadherin signaling pathways and vascular leak phenomena. Recent studies demonstrate translational applications including oligonucleotide drugs for diabetic retinopathy and cerebral cavernous malformations, alongside investigations into tumor angiogenesis and immune cell trafficking. Analysis of her 15 most recent publications (2024-2013) reveals consistent emphasis on vascular senescence in neurodegeneration, with growing focus on therapeutic targeting of the SphK1/S1P axis in cancer and miR-27a in vascular disorders. Methodologically, her work integrates mouse disease models, molecular signaling analysis, and translational drug development across oncology and neurology. Dr. Ting has secured competitive funding including the 2021 Philip Bushell Foundation grant for Alzheimer's early treatment strategies and the 2019 NHMRC Ideas Grant on endothelial senescence. She collaborates extensively with Sydney-based researchers like Gamble, Vadas, and Zhao, contributing to interdisciplinary projects at the Brain and Mind Centre that investigate vascular contributions to neurological diseases.

Lefteris Zachariaمشاهده پروفایل

دانشیار

• Pharmacology
• Drug Development
• Estradiol Metabolite Biology
• +۹ مورد دیگر

Lefteris Zacharia is an Associate Professor at the University of Nicosia , School of Life and Health Sciences, Department of Health Sciences. He combines academic expertise with industry experience in pharmacology, drug development, and regulatory affairs. BSc in Biochemistry from Denison University (1998) PhD in Pharmacology from University of Pittsburgh School of Medicine (2002) MBA from Katz Graduate School of Business, University of Pittsburgh (2007) His research focuses on estradiol metabolite biology in Alzheimer’s disease, pre-eclampsia, and ischemia-reperfusion injury, alongside investigating inflammation resolution in cancer and cardiovascular diseases. He also explores peritoneal adhesions and nicotine metabolism inhibition for smoking cessation. Recent publications emphasize animal models for cognitive impairment, adrenergic receptor targeting in neurodegeneration, and in vitro systems for metastatic cancer research. His work bridges translational pharmacology and clinical applications . He has participated in European Union grants as principal investigator and NIH grants as co-investigator, with an h-index of 24 and over 1400 citations.

• Natural Product Isolation
• Medicinal Chemistry
• Drug Development
• +۳ مورد دیگر

Kine Østnes Hansen is an Associate Professor at the Department of Pharmacy , UiT The Arctic University of Norway , specializing in Natural Products and Medicinal Chemistry . Her research focuses on marine natural product isolation, characterization, and translational drug development, with particular emphasis on OMICs analysis of complex biological samples like algal biomass. Key Projects : AlgScaleUP, HOTBIO, CandRAS Teaching : Courses FAR-1302, FAR-3311, FAR-3312, FAR-2302 Spin-off Affiliation : Researcher at KinSea Lead Discovery AS Her recent work in 2025 includes DYRK kinase inhibition for diabetes therapy and discovery of ophiobolin-type sesterterpenes. Earlier studies (2019–2021) explored Arctic bryozoan alkaloids, antimicrobial peptides from ascidians, and novel lipid structures from marine bacteria. Techniques employed span UPLC-HR-MS2 metabolomics , LC-Orbitrap lipidomics , and NMR spectral analysis for structural elucidation of bioactive compounds.

Sean Thatcherمشاهده پروفایل

استادیار

• Abdominal aortic aneurysms
• Atherosclerosis
• Angiotensin converting enzyme-2 (ACE2)
• +۶ مورد دیگر

Sean Thatcher, PhD, is an Assistant Professor at the Lewis Katz School of Medicine, Temple University, specializing in Biomedical Education and Data Science. His research focuses on abdominal aortic aneurysms, atherosclerosis, ACE2 enzyme function, sex differences, and renin-angiotensin system (RAS) mechanisms. PhD in Physiology from Marshall University Post-doctoral training in Pharmacology & Nutritional Sciences at University of Kentucky Key research areas: Sex-specific cardiovascular disease mechanisms ACE2 enzyme's role in hypertension and aneurysms Hybrid educational methodology development Vascular smooth muscle cell dynamics Recent publications highlight work on: Sex chromosome impacts on aortic pathology Estrogen's protective effects in vascular disease ACE2-deficiency models in metabolic disorders Myosin inhibition techniques Scientific recognition: F32 Ruth L. Kirschstein National Research Service Award (2009) Faculty of the Year (University of Kentucky, 2019) Professional memberships: American Physiological Society (APS) American Society for Pharmacology and Experimental Therapeutics (ASPET) American Heart Association (AHA) Society for Sex Differences (OSSD)

• Ophthalmology
• Retinal Surgery
• Vitreoretinal Disease
• +۵ مورد دیگر

Rajeev S. Ramchandran, M.D., M.B.A. is an Associate Professor in the Department of Ophthalmology at the University of Rochester School of Medicine and Dentistry, specializing in Retina & Vitreous Services at the Flaum Eye Institute. He is a board-certified ophthalmologist with extensive clinical experience in retinal surgeries, laser therapy, intravitreal injections, and medical retina care. His research interests span multiple domains including telemedicine applications in ophthalmology, diabetic retinopathy screening protocols, retinal imaging technology, health policy and economics, and international ophthalmology. Dr. Ramchandran has developed significant expertise in implementing teleophthalmology programs to improve diabetic retinopathy surveillance in primary care settings and urban low-income populations. Analysis of his recent publications reveals a strong focus on retinal imaging technology development, teleophthalmology program evaluation, and the intersection of eye care with broader health systems. His work demonstrates consistent contributions to improving access to eye care in rural communities and underserved populations through innovative telemedicine solutions. John M. Brophy Award (2013) Operations Faculty Award (2013) Beta Sigma Gamma Honor Society member (2013) Distinction in Research during medical school (2003) Summa Cum Laude graduate from University of Pennsylvania (1998) Phi Beta Kappa member (1998) Dr. Ramchandran actively contributes to clinical education and has participated in numerous research collaborations across disciplines including oncology, pulmonology, and neuroscience. His laboratory work has included significant contributions to understanding vascular biology, ciliogenesis mechanisms, and molecular pathways in retinal disease. He maintains an active clinical practice serving patients in the Rochester area, Finger Lakes Region, and Western New York.

• Pharmacology and Therapeutics
• Basic Pharmaceutics Sciences
• Analytical Chemistry
• +۴ مورد دیگر

Dr. Sercan Yildirim is an Assistant Professor at Karadeniz Technical University's Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences. He holds a PhD in Analytical Chemistry from Karadeniz Technical University (2020) and an undergraduate degree in Pharmacy from Anadolu University (2014). Education: PhD (2020) and MSc (2014) in Analytical Chemistry. Current Role: Assistant Professor (2020–Present), teaching undergraduate and postgraduate courses in analytical chemistry and pharmaceutical analysis. Research Interests: Spanning Analytical Chemistry Pharmaceutical Analysis Bioanalytical Methods Environmental Drug Monitoring Pharmacology and Therapeutics His work focuses on developing advanced chromatographic and electrochemical techniques for drug analysis, environmental monitoring, and pharmaceutical quality control. Recent Publications highlight innovations in Deep eutectic solvent-based microextraction Lab-in-syringe automation for HPLC Nanomaterials in electroanalytical sensors Pharmaceutical nanoparticle formulation DNA interaction studies of antidepressants Aluminium toxicity in food products Grants & Projects: He has led or contributed to 8 funded projects since 2016, including method development for fluoroquinolone antibiotics and beta-blockers in complex matrices.

• Diabetes
• Obesity
• Endocrinology
• +۴ مورد دیگر

Professor Konstantinos Tsigos is affiliated with the Hellenic Open University, serving in the Department of Nutrition and Metabolism. His academic career spans over three decades, with expertise in diabetes, obesity, and endocrinology. Medical Degree, University of Athens (1982) PhD, University of Manchester Medical School (1991) Specialty in Endocrinology, Hope Hospital, Manchester (1987-1991) Senior Research Fellow, NIH Clinical Center (1991-1995) Research Director, EKEDI, Athens (1996-2005) His research focuses on the pathogenesis and treatment of diabetes and obesity, stress-related cardiometabolic disorders, cytokine effects on endocrine axes, and hormone resistance mechanisms. He has contributed extensively to understanding inflammation's role in metabolic dysregulation and hormone-receptor interactions. Key trends in his publications include molecular endocrinology, obesity management, cytokine dynamics, and clinical guidelines for metabolic disorders. His work bridges basic research (e.g., receptor mutations) and public health applications (e.g., European obesity guidelines).

• Functional genetic variation
• Type 2 diabetes
• CRISPR genome editing
• +۷ مورد دیگر

Sebastian Kalamajski is a Senior Lecturer in Biomedical Laboratory Science at the Faculty of Natural Science, Department of Bioanalysis. His research bridges experimental genetics and data science to study functional genetic variation impacting human health, with primary focus on type 2 diabetes and obesity-related metabolic disorders. Research Interests: CRISPR-based allele substitution in fat and beta cells Identification of causal genetic variants for disease phenotypes Adipose tissue hyperplasia and insulin responsiveness International collaborations with Lund University, Broad Institute/Harvard, and Ulm University Integration of data science and experimental methodologies Recent Publication Trends: 2024 articles examine social trust genetics, PPARGC1B variants in adiposity, and molecular modeling of genetic risks using stem cells. Earlier works (2023) focus on phenome-wide analyses of obesity-diabetes discordance. Academic Activities: Peer-review work for journals: Pharmacogenomics , Diabetologia , and Animal Models and Experimental Medicine Supervision of PhD students and research projects Examination committee leadership

• Pediatric Endocrinology
• Diabetes
• Congenital Adrenal Diseases
• +۳ مورد دیگر

Rachel Scott is an Assistant Clinical Professor in the Department of Pediatrics at the Faculty of Medicine, affiliated with CHU Sainte-Justine. Her clinical work focuses on pediatric endocrinology, including diabetes management and congenital adrenal disorders. She teaches and directs the Pediatric Endocrinology and Metabolism Program. MD from Dalhousie University (2000) Pediatrics residency at IWK Health Centre (2004) Pediatric endocrinology fellowship at CHU Sainte-Justine (2007) Her research interests span: Pediatric diabetes transition care Congenital adrenal diseases Genetic mechanisms in endocrine disorders Adolescent chronic disease management Adrenal-insufficiency-diabetes comorbidity Animal model translational research Her publications focus on neonatal diabetes genetics, P450 oxidoreductase deficiency, and rheumatology transition clinics. She has collaborated with labs like Dr. Walter Miller's at UCSF. Since 2010, she has conducted diabetes/endocrinology clinics, including regional outreach, and taught the MMD2233 course since 2011.

Britta Svorenمشاهده پروفایل

دانشیار بالینی

• Type 1 Diabetes
• Pediatric Endocrinology
• Diabetes Complications
• +۳ مورد دیگر

Britta Svoren, M.D., serves as Associate Professor of Clinical Pediatrics (Part-Time) in the Department of Endocrinology at the University of Rochester School of Medicine and Dentistry. She is actively affiliated with the University of Rochester Medical Faculty Group (URMFG) and Accountable Health Partners (AHP), providing specialized care for children, adolescents, and young adults with diabetes and endocrine disorders while maintaining a 4.9/5 patient satisfaction rating. Her academic foundation includes: MD from SUNY at Buffalo-School of Medicine & Biomedical Sciences (2000) Comprehensive training at Boston Children's Hospital: Internship (2000-2001), Residency (2001-2003), and Pediatric Endocrinology Fellowship (2003-2006) Dr. Svoren's research program focuses on preventing type 1 diabetes complications while preserving pediatric growth, development, and family functioning. She investigates environmental triggers of pancreatic autoimmunity and leverages continuous glucose monitoring technologies to optimize diabetes management, balancing clinical innovation with family-centered care approaches. Her publication history (2003-2009) reveals consistent emphasis on pediatric diabetes pathophysiology and management, with recurring themes in autoimmune mechanisms, technology integration, and complication prevention across diverse clinical scenarios including vitamin D deficiency, insulin pump durability, and endocrine disruptions from environmental exposures. Her scientific recognition includes: Harvard Medical School Scholars in Medicine Fellowship Award (2007) Eli Lilly and Company Fellowship Research Training Grant (2004) NIH Pediatric Research Loan Repayment Grant (2003-2007) Children's Hospital of Buffalo Prize (2000) Alpha Omega Alpha Honor Society (2000) Dean's List for Academic Excellence (1997-1999) Phi Beta Kappa Honor Society (1994) Dr. Svoren has secured significant research funding through NIH and industry partnerships to advance pediatric diabetes care, with her clinical excellence consistently reflected in patient testimonials praising her thorough explanations, collaborative decision-making, and compassionate approach to complex endocrine conditions in young patients.

• Diabetes
• Autophagy
• Pancreatic Beta Cells
• +۳ مورد دیگر

Catherine Arden is a researcher at Newcastle University , focusing on diabetes, autophagy, and pancreatic beta cell survival. Her work explores the molecular mechanisms of metformin therapy, GLP-1 signaling, and lysosomal dysfunction in diabetes complications.

• Diabetes Research
• Endocrinology
• Islet Transplantation
• +۴ مورد دیگر

Professor James Shaw is a leading academic at Newcastle University specializing in diabetes research with extensive contributions to hypoglycemia management, islet transplantation, and cystic fibrosis-related diabetes. His work bridges clinical practice and molecular research, focusing on innovative interventions for diabetes complications and glucose monitoring technologies. Primary Affiliation: Faculty of Medical Sciences, Newcastle University Research Leadership: Principal investigator for multiple clinical trials including HypoCOMPaSS and PHT2 Collaborations: Works with international consortia on islet transplantation and diabetes technology assessment Shaw's research centers on diabetes pathophysiology with particular emphasis on hypoglycemia awareness mechanisms, pancreatic islet function, and cystic fibrosis-related metabolic complications. His laboratory investigates molecular pathways involving ER stress, oxidative damage, and CFTR modulation in diabetes development. Clinically, he pioneers psycho-educational interventions for hypoglycemia prevention and develops novel monitoring protocols using continuous glucose monitoring systems. His work frequently addresses real-world challenges in diabetes management across diverse patient populations including children, elderly, and transplant recipients. Recent publications demonstrate a clear trajectory toward digital health solutions for diabetes self-management, molecular characterization of diabetes subtypes, and optimization of transplantation outcomes. His research integrates patient-reported outcomes with physiological metrics to create holistic diabetes care frameworks. Shaw's team has significantly advanced understanding of hypoglycemia symptomatology and awareness restoration through structured interventions. Principal Investigator: HypoCOMPaSS trial (hypoglycemia awareness restoration) Principal Investigator: PHT2 trial (hypoglycemia prevention in type 2 diabetes) Co-investigator: SIGNET trial (organ donation optimization) Shaw mentors numerous early-career researchers and clinicians, fostering expertise in diabetes clinical trials methodology and translational research. His team receives substantial funding from major UK research councils and diabetes charities for investigator-led trials and mechanistic studies. Current projects focus on exercise physiology in diabetes, digital therapeutics for hypoglycemia prevention, and molecular diagnostics for cystic fibrosis-related diabetes.

Adrian Woolfمشاهده پروفایل

استاد

• Pediatrics
• Nephrology
• Regenerative Medicine
• +۱۱ مورد دیگر

Professor Adrian Woolf holds the Chair in Paediatric Science at the University of Manchester since 2010, affiliated with the Faculty of Biology, Medicine and Health and the Division of Cell Matrix Biology & Regenerative Medicine . He serves as an Honorary Consultant in Paediatric Nephrology at Royal Manchester Children's Hospital (2010–2022) and an Honorary Professor at University College London (2010–present). Education : St Paul's School, Corpus Christi College Cambridge, Westminster Medical School. Qualifications include MB BS, MA, MRCP II, MD Thesis. His research focuses on congenital kidney and urinary tract malformations, their genetic basis, and translational therapies using growth factors, precursor cells, and gene therapy. He pioneered human pluripotent stem cell models for renal tract development and disease. His 188 publications have high impact (h=74, g=120). Recent work includes gene therapy for bladder disease, organoid modeling of kidney malformations, and macrophage studies in surgical adhesions. Grants from MRC, Kidney Research UK, and LifeArc underscore his leadership in regenerative medicine and rare kidney diseases . Scientific Awards : The Renal Association's Lockwood Award (2015) The de Wardener Lecturer (2016) He has supervised 23 PhD, 3 MD, and 12 MRes theses, with three former students becoming Professors at UCL. Current advisees include S Almuwallad, T Schlesinger, and S Al Madhy. His collaborations span institutions in the UK, Europe, and beyond, emphasizing interdisciplinary research in genetics, cell biology, and clinical nephrology.

Ted Jardetzkyمشاهده پروفایل

استاد

• Structural Biology
• Virology
• Immunology
• +۴ مورد دیگر

Ted Jardetzky is a Professor of Structural Biology at Stanford University, with affiliations in Bio-X, the Maternal & Child Health Research Institute (MCHRI), and the Stanford Cancer Institute. His research focuses on the structural and functional analysis of macromolecular complexes involved in viral pathogenesis, allergic hypersensitivities, and cellular signaling pathways. PhD in Biophysical Chemistry, University of Basel (1986) BS in Chemistry, Stanford University (1982) His laboratory investigates molecular mechanisms of paramyxovirus and herpesvirus entry, IgE-receptor dynamics, and TGF-beta signaling. Recent work includes designing disruptive anti-IgE therapeutics and characterizing neutralizing monoclonal antibodies for respiratory viruses. Key publication trends span structural immunology , allergic disease intervention , and viral fusion protein inhibition , with a focus on conformational dynamics , receptor binding , and therapeutic antibody design . Pew Scholar in the Biomedical Sciences (1996-2001) Investigator Award, Cancer Research Institute (1999-2003) NIH Merit Award (2001-2011) Fellow, American Academy of Microbiology (2008) He mentors graduate students and postdoctoral fellows in Biophysics, Immunology, and Structural Biology PhD programs. His lab collaborates on projects targeting allergic disease mechanisms and viral entry inhibition .