جستجوی استاد راهنمای دانشگاهی

Henrik Peter Sahlin Pettersen is an Associate Professor at the Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU). His research focuses on molecular mechanisms of DNA repair, cancer biology, and applications of digital pathology. He is affiliated with the Molecular Biology research group (http://www.ntnu.no/dmf/ikm/molbiol) and the DNA Repair and Genome Stability group (http://www.ntnu.no/dmf/ikm/dna-r). His work spans interdisciplinary areas including: Genomic instability and mutagenesis in cancer Role of tumor-associated macrophages in meningiomas Development of AI-driven tools for histopathological analysis Quantitative immunohistochemistry methods Recent studies highlight contributions to: IBD treatment mechanisms using patient-derived colonoids Disease differentiation in inflammatory bowel diseases through T-cell analysis Automated breast cancer segmentation techniques He actively collaborates across disciplines, integrating molecular biology with computational pathology solutions. His presentations at international conferences reflect commitment to advancing translational research in oncology and digital diagnostics.

• Molecular Biology
• DNA Repair
• Genome Stability
• +۵ مورد دیگر

Elin Moe serves as an Associate Professor II in Biomolecular and Structural Chemistry at the Department of Chemistry, UiT The Arctic University of Norway. Her research and teaching activities are centered around protein production technology and structural biology approaches to understanding DNA repair mechanisms. Dr. Moe's research focuses on the Base Excision Repair (BER) pathway in Deinococcus radiodurans , an extremophile bacterium renowned for its extraordinary resistance to ionizing radiation (tolerating doses up to 5,000 Grays without loss of viability, compared to 50 Grays for most organisms). Her work employs integrated structural biology methodologies to investigate how this organism repairs DNA damage. She has extensively studied various DNA repair enzymes including uracil-DNA glycosylase, endonuclease III, DNA ligase, and other components of the BER pathway in D. radiodurans . Additionally, her research extends to cold-adapted enzymes from marine organisms such as Atlantic cod and various Vibrio species, examining their structural adaptations to extreme environments. Her recent publications reveal a broadening research scope that now includes PARP1-related research with implications for cancer therapy, demonstrating the translational potential of her fundamental research on DNA repair mechanisms. The articles show a consistent pattern of structural and functional characterization of DNA repair proteins, with increasing applications in biomedical contexts. Dr. Moe teaches Kje-3603 Protein production technology and has collaborated extensively with researchers both within UiT and internationally. Her work bridges fundamental molecular biology with potential applications in radiation biology, extremophile adaptation, and cancer therapeutics.

• Structural Biology
• DNA Repair
• Base Excision Repair
• +۵ مورد دیگر

Tahira Riaz is a Lecturer and Senior Engineer in the Department of Microbiology at the University of Oslo, affiliated with the Faculty of Medicine. Her research focuses on antimicrobial resistance, particularly Mycobacterium tuberculosis (Mtb) biofilm formation and drug discovery. She leads a postdoctoral project funded by the EU’s Joint Programming Initiative on Antimicrobial Resistance (JPIAMR), investigating novel Mycobacterial Tolerance Inhibitors (MTIs) against multidrug-resistant TB. Riaz’s work combines mass spectrometry, proteomics, and mutant analysis to uncover MTIs’ mechanisms of action and synergy with existing TB drugs. Her teaching roles include supervising Bachelor’s students and leading microbiology laboratory courses for medical students. She has held deputy roles representing temporary academic staff on institutional councils. Key research interests include proteomics, immunology, and bioinformatics, with a focus on understanding bacterial pathogenesis and developing precision medicine strategies. Riaz’s publications span proteomic analyses of Mtb strains, Alzheimer’s disease biomarkers, and bacterial DNA repair mechanisms. She collaborates internationally on projects addressing antimicrobial resistance and drug discovery. Her work bridges fundamental research with clinical applications, emphasizing translational outcomes in infectious disease management.

• Mass spectrometry
• Proteomics
• Bioinformatics
• +۳ مورد دیگر

Kristin Solum Steinsbekk is an Associate Professor in the Department of Biomedical Laboratory Science at the Norwegian University of Science and Technology (NTNU), affiliated with the Faculty of Natural Sciences. Her expertise spans bioethics, biobanking, and personalized medicine, with a focus on ethical challenges in genomic research and clinical applications. Her research interests include the ethical implications of commercialization in biobanking, consent models for genomic studies, and the societal impact of personalized medicine. She has contributed to interdisciplinary education initiatives, particularly in biomedical laboratory science and medical genetics, teaching courses such as HBIO3015 and HBIOT2031. Her work often addresses the balance between scientific innovation and ethical responsibility, including topics like incidental findings management, participant engagement in research, and the implications of digital health technologies. She has presented at numerous conferences, including the European Conference on Philosophy of Medicine and the Norwegian Society for Human Genetics meetings. Steinsbekk holds a doctoral degree from NTNU (2013) focusing on biobank ethics and has authored or co-authored over 20 peer-reviewed articles, covering topics from genetic mutation analysis to Kantian ethics in medical technology.

• Bioethics
• Biobanking Ethics
• Personalized Medicine
• +۳ مورد دیگر

Magnar Bjørås is a Researcher at the Department of Microbiology , University of Oslo. His work spans interdisciplinary research at the intersection of molecular biology, DNA repair, and microbiology, with a particular focus on bacterial pathogenesis and host-virus interactions. Key research themes: DNA repair enzymes, epitranscriptomic modifications, and gene expression dynamics Active collaborations with teams across Norway and international institutions Developed novel methodologies for nucleic acid extraction and antimicrobial peptide design Recent publications highlight his expertise in: DNA glycosylase functions in neurogenesis and metabolic diseases Combinatorial antiviral therapies against coronaviruses and enteroviruses Epigenetic mechanisms in immunodeficiency and cancer His group employs cutting-edge approaches in: Redox biology and oxidative stress responses Computational analysis of regulatory mutations Nanotechnology for biomedical applications

• DNA Repair Mechanisms
• Epitranscriptomics
• Gene Expression Regulation
• +۳ مورد دیگر

Marivi Nabong Moen is a Senior Engineer and Head Engineer at the Amino Acid Transporters Laboratory within the Faculty of Medicine at the University of Oslo. She is also associated with the Synaptic Plasticity research group, contributing to technical and research initiatives in molecular biology and biochemistry. Education: PhD (2012) from the University of Stavanger with a thesis on Mechanisms and structures in base lesion repair. MSc (2006) in Molecular Biology, Biochemistry, and Physiology from the University of Oslo. Her research focuses on DNA repair mechanisms, particularly base lesion repair, enzymatic activity of glycosylases (e.g., UNG, hSMUG1, ALKBH1/ALKBH2), and implications in genomic stability. She has explored diverse organisms including hyperthermophilic archaea, mammals, and Arabidopsis thaliana, with applications in neurobiology, cancer research, and plant biology. Recent work includes studies on immunoglobulin gene diversification and neuronal potassium fluxes. Publications Overview: Her articles span DNA repair pathways, enzymatic functions, and cross-species genomic stability, with collaborations on cancer research, stem cell transcriptional networks, and extremophile biology. Technical Affiliations: Member of the Engineering Working Group, specializing in molecular biological techniques, animal work, and cell culture under HSE protocols. Labs: Affiliated with the Amino Acid Transporter Laboratory and Synaptic Plasticity group at the University of Oslo.

• Molecular Biology
• Biochemistry
• DNA Repair
• +۳ مورد دیگر

Ane Sørlie Kværner is a Postdoctoral Fellow at the Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, specializing in nutritional epidemiology with a focus on diet-cancer relationships. Her research examines how dietary patterns influence colorectal cancer development, progression, and treatment outcomes through rigorous epidemiological and clinical methods. Her primary research interests include: Diet and Cancer Cancer Screening Nutritional Interventions Nutritional Epidemiology Dietary Assessment Methods Dr. Kværner's publication record demonstrates expertise in molecular mechanisms of diet-cancer interactions, particularly DNA damage and repair processes. Her recent work examines plant-based diets, red meat consumption, body composition, and gut microbiome interactions in colorectal cancer contexts. She frequently employs advanced methodologies including randomized controlled trials, prospective cohort studies, and molecular biomarker analyses. Her research collaborations span multiple institutions including the Cancer Registry of Norway, Norwegian Institute of Public Health, and Harvard T.H. Chan School of Public Health. Current projects include the CRCbiome study, KoloPrev, and the Norwegian Dietary Guidelines and Colorectal Cancer Survival study (CRC-NORDIET).

• Diet and Cancer
• Cancer Screening
• Nutritional Interventions
• +۴ مورد دیگر

Robin Mjelle is a Research Fellow at the Department of Clinical and Molecular Medicine , Norwegian University of Science and Technology (NTNU) . Their work bridges molecular oncology, immunology, and bioinformatics, with a focus on microRNA biomarkers in cancers and metabolic diseases. University: Norwegian University of Science and Technology (NTNU) Department: Department of Clinical and Molecular Medicine Academic Rank: Research Fellow Research Interests: MicroRNA profiling for early cancer detection and prognosis Toll-like receptor signaling in hematologic malignancies Epigenetic regulation in metabolic and autoimmune diseases Longitudinal transcriptomics analysis tools Host-microbiota interaction profiling Scientific Contributions: Developed sMETASeq pipeline for combined microbiota and host RNA analysis (2020) Created TiSA time-series analysis tool for transcriptomics (2023) Identified miR-105-5p as survival predictor in multiple myeloma (2022) Discovered miR-320 association with lung cancer progression (2022) Elucidated IL-32's role in myeloma cell metabolism (2021)

• MicroRNA Biomarkers
• Cancer Genomics
• Molecular Oncology
• +۶ مورد دیگر

Mansour Akbari is a Senior Lecturer in the Department of Medical Biology at UiT The Arctic University of Norway, Tromsø. He has held academic positions at prestigious institutions including the University of Copenhagen and NTNU, with expertise spanning molecular biology, DNA repair, and aging research. Dr. Akbari received his Doctor Philosophiae (Dr. Philos.) from NTNU, Norway in 2006. His academic career includes: 2007-2010: Postdoc at the Institute for Cancer Research and Molecular Medicine, NTNU 2011-2014: Assistant Professor at the Institute for Cellular and Molecular Medicine (ICMM), University of Copenhagen, Denmark 2015-2021: Associate Professor at ICMM, University of Copenhagen, Denmark 2022-Present: Senior Lecturer at the Department of Medical Biology, UiT The Arctic University of Norway Dr. Akbari's research focuses on the intersection of aging, inflammation, DNA repair mechanisms, and their implications for cancer and neurodegenerative diseases. His work particularly examines mitochondrial DNA maintenance, the role of DNA repair enzymes in preventing age-related pathologies, and the connection between genomic instability and neurodegenerative disorders like Alzheimer's and Parkinson's disease. His research employs various model systems including human cell cultures, C. elegans, and mouse models of tauopathy to elucidate fundamental mechanisms linking DNA damage response to age-related diseases. Analysis of Dr. Akbari's recent publications reveals a strong focus on the connections between DNA repair pathways, mitochondrial function, and neurodegenerative diseases. His work demonstrates how deficiencies in DNA repair mechanisms contribute to age-related pathologies, particularly through the accumulation of mitochondrial DNA damage and subsequent inflammatory responses. A significant portion of his research examines the cGAS-STING pathway, which connects cytosolic DNA sensing to inflammatory responses in aging. His publications span high-impact journals across molecular biology, neuroscience, and aging research, reflecting the interdisciplinary nature of his work. Dr. Akbari has been actively involved in teaching courses including: MBI-2103: Immunology and Transfusion Medicine TPL-1004: Biochemistry MBI-2011: DNA Repair and Recombination MBI-3004: Genomic Integrity and Cancer

• Aging
• Inflammation
• DNA Repair
• +۲ مورد دیگر

Ole Jacob Nilsen is a Lecturer at the Department of Urology, University of Oslo. His clinical and research work focuses on urinary tract disorders, urethroplasty techniques, and medical device validation. Institution: University of Oslo Department: Department of Urology Contact: o.j.nilsen@medisin.uio.no Research Interests Clinical validation of MEMS-based pressure sensors for urodynamic studies Long-term outcomes of male stress urinary incontinence surgical interventions Comparative effectiveness of urethroplasty approaches for bulbar strictures Optimization of postoperative catheterization protocols Publication Trends His recent work (2021–2025) emphasizes clinical validation of microelectromechanical systems (MEMS) in urology, comparative surgical outcome studies, and evidence-based postoperative care protocols. Collaboration Networks Collaborates with urologists and medical researchers across Scandinavia, including Henriette Veiby Holm and Jean-Luc Boulland.

• Urology
• Urodynamic Studies
• Urinary Tract Disorders
• +۲ مورد دیگر

Lars Eide is a Professor and Research Leader at the Faculty of Medicine, University of Oslo (UiO) and Oslo University Hospital (OUS) . His work focuses on mitochondrial DNA (mtDNA) repair, oxidative damage, and its role in neurodegenerative and metabolic diseases. He leads the Mitogroup research team and manages the PhD course "Biomarkers for Clinical Research". Research Interests Mitochondrial DNA modifications and repair mechanisms Interplay between mitochondrial function and mtDNA dynamics Metabolic disorders (e.g., Maple Syrup Urine Disease) Neurodegenerative diseases (e.g., Huntington's, Leigh Syndrome) Lipid metabolism and atherosclerosis Cancer metabolism (e.g., pancreatic and prostate cancer) Recent Article Trends include studies on branched-chain fatty acids in diabetes, mtDNA repair in neurogenesis, and metabolomic profiling for cancer biomarkers. His work spans biochemistry , genetics , and clinical applications , with collaborations across institutions like UiO, OUS, and NTNU. Projects include "Functional effects of mitochondrial heteroplasmy" and "Metabolic causes of mitochondrial dysfunction." He holds a Dr. Scient in Mathematics/Natural Sciences from UiO (1997) and a Civil Engineering in Chemistry (Trondheim, 1992).

• Mitochondrial Biology
• DNA Repair
• Molecular Genetics
• +۳ مورد دیگر

Hilde Loge Nilsen is a Professor at the Department of Clinical Molecular Biology, University of Oslo, and holds dual roles as a Researcher and problem-based learning supervisor at the Medical Faculty. She leads the 'DNA Repair' group and has affiliations with the Biotechnology Centre of Oslo and the research group 'Genome instability in ageing and disease'. Her education includes a Dr. ing. from NTNU (2000) and postdoctoral work at Cancer Research UK (2000–2004). Key research interests focus on DNA/RNA quality control mechanisms in disease, particularly their roles in cancer, neurodegeneration, and aging. Her work bridges DNA repair’s traditional mutation-prevention role with its emerging functions in neurobiology and RNA integrity. Her research achievements include identifying uracil accumulation mutation signatures, linking DNA repair defects to neurodegeneration, and discovering SMUG1’s role in RNA quality control. Recent studies emphasize NAD+’s role in mitigating neurodegeneration and mitochondrial dysfunction. Collaborations span academic and clinical institutions, with contributions to understanding autophagy induction and transcriptomic compensation in DNA repair-deficient organisms. She actively supervises medical education and contributes to interdisciplinary research teams.

• DNA repair
• Cancer
• Neurodegeneration
• +۳ مورد دیگر

Henrik Peter Sahlin Pettersen is an Associate Professor at the Norwegian University of Science and Technology (NTNU), affiliated with the Department of Clinical and Molecular Medicine within the Faculty of Natural Sciences and Technology. His research focuses on molecular mechanisms of DNA repair, genomic instability in cancer, and applications of artificial intelligence in digital pathology. He has published extensively in high-impact journals such as Neuropathology and Applied Neurobiology , Diagnostic Pathology , and Nucleic Acids Research . Key research areas include the role of uracil-DNA glycosylases in DNA repair pathways, tumor-associated macrophage biology, and the development of machine learning tools for histopathological analysis. His work bridges molecular biology, clinical pathology, and computational methods, with recent studies investigating therapeutic effects on IBD-derived colonoids and T-cell dynamics in inflammatory bowel diseases. Dr. Pettersen collaborates with institutions like St. Olavs Hospital and SINTEF, emphasizing translational research in personalized medicine. He actively participates in academic outreach, delivering lectures on digital pathology, proteomics, and the societal impact of scientific advancements. His research has contributed to understanding genomic uracil’s role in lymphoma development and improving diagnostic accuracy through automated image analysis systems. Notable projects include developing the H2G-Net segmentation framework for gigapixel histopathology images and investigating the clinicopathological relevance of tumor-associated macrophages in meningiomas. His work highlights interdisciplinary approaches to address challenges in oncology, immunology, and medical technology.

• Molecular Cell Biology
• DNA Repair
• Cancer Biology
• +۳ مورد دیگر

Arne Klungland is a Professor and Centre Director at the Centre for Embryology and Healthy Development (CRESCO), affiliated with the University of Oslo and Oslo University Hospital. His research spans molecular biology, epigenetics, DNA repair, and embryology, with a focus on RNA modifications such as m6A and m1A methylation. University: University of Oslo School: Faculty of Medicine Department: Centre for Embryology and Healthy Development (CRESCO) Academic Rank: Professor Email: arne.klungland@medisin.uio.no His research interests include epigenetics, epitranscriptomics, DNA repair, meiosis, and embryology. His work investigates how RNA modifications regulate gene expression during development and disease, particularly in gametogenesis, stem cell biology, and cancer. He has made significant contributions to understanding m6A and m1A dynamics in mammalian systems. The recent articles highlight a strong trend in RNA epigenetics, particularly m6A and m1A modifications in embryonic development, stem cells, and cancer. His research integrates high-throughput sequencing, molecular biology, and functional genomics to explore post-transcriptional regulation in development and disease. Scientific awards are not mentioned in the provided text. Klungland leads a dynamic research group at CRESCO, mentoring students and postdoctoral researchers. He has been involved in numerous collaborative research projects on DNA repair, RNA modifications, and developmental biology. His lab utilizes advanced techniques such as single-cell RNA mapping, ChIP, and functional assays in mouse and human models. While specific grant details are not listed, his consistent publication in top journals indicates sustained funding and research activity. He leads the Centre for Embryology and Healthy Development (CRESCO), a multidisciplinary research center focused on understanding molecular mechanisms of embryogenesis, fertility, and developmental disorders. The center fosters collaboration between basic scientists and clinicians to translate findings into improved reproductive health outcomes.

• Epigenetics
• Epitranscriptomics
• DNA Repair
• +۷ مورد دیگر

Mirta Mittelstedt Leal de Sousa serves as a Senior Researcher in the Department of Clinical and Molecular Medicine at the Norwegian University of Science and Technology (NTNU), Faculty of Medicine and Health Sciences. Her laboratory is situated at Laboratoriesenteret, Øya campus in Trondheim, Norway. Her educational background includes a PhD in Molecular Medicine (2012) from NTNU's Department of Cancer Research and Molecular Medicine, an MSc in Molecular Biology (2003) from the University of Brasília, Brazil, and a BSc in Chemistry (2000) from the same institution. She completed extensive postdoctoral training at NTNU (2012-2020) and at Lawrence Berkeley National Laboratory/Joint Bioenergy Institute in California (2012-2013). Dr. Sousa's research spans proteomics, neuroscience, biochemistry, DNA repair mechanisms, and cancer biology. Her work consistently investigates how oxidative DNA damage impacts cellular function, with particular emphasis on base excision repair pathways, epitranscriptomic modifications, and their roles in neurodegenerative disorders, immunodeficiency, and oncogenesis. Recent publications demonstrate her pivot toward pandemic-related research, examining DNA repair activation in severe COVID-19 and epitranscriptomic alterations in critical illness. Analysis of her 15 most recent publications reveals strong thematic continuity in DNA damage response mechanisms while expanding into clinical applications including cancer therapeutics, neurodevelopmental disorders, and diagnostic nanotechnology. Her work frequently employs advanced proteomic and genomic techniques to elucidate molecular pathways in disease contexts. Her scientific contributions include development of NAxtra magnetic nanoparticles for nucleic acid isolation, characterization of OXR1's role in histone methylation, and mechanistic studies of DNA glycosylases in neurological dysfunction and cancer. Collaborative work spans international institutions including University of California, University of Oslo, and University of Brasília. Dr. Sousa maintains active research in multiple high-impact areas including oxidative stress response, epigenetic regulation, and translational applications of DNA repair knowledge. Her laboratory continues to produce significant findings in both fundamental molecular mechanisms and clinically relevant disease processes.

• Proteomics
• Neuroscience
• Biochemistry
• +۵ مورد دیگر