جست‌وجوی استاد و پژوهشگر

• Allergy and Immunology
• Allergic Rhinitis
• Food Allergy
• +۳ مورد دیگر

Roy Gerth van Wijk serves as a Researcher at Erasmus University Medical Center within the Department of Internal Medicine, focusing on clinical allergy and immunology research. With 275 documented research outputs including articles, reviews, and book chapters, his work centers on allergic diseases affecting respiratory and gastrointestinal systems, particularly through collaborations evident in recent high-impact publications. His research interests prominently feature Allergic Rhinitis (including vasomotor and perennial subtypes), Food Allergy mechanisms (especially peanut-related disorders), and Asthma pathophysiology. He investigates diagnostic methodologies like skin prick testing, allergen avoidance strategies, and immunological responses involving Immunoglobulin E and Histamine mediators. Current projects examine cellular immune regulation during immunotherapy and safe allergen introduction protocols for high-risk pediatric populations. Recent publication trends (2024-2025) demonstrate concentrated efforts in pediatric food allergy management, with emphasis on home-based allergen introduction safety, diagnostic test validation for fruit/vegetable allergies, and meta-analyses of environmental interventions for asthma. His work bridges clinical practice and immunological research to develop evidence-based protocols for allergic disease management. Dr. van Wijk has supervised 10 research projects, mentoring junior researchers in allergy/immunology. His collaborative network spans international institutions as shown by co-authorship patterns and social media engagement (including X posts and Mendeley readership), indicating significant influence in the allergy research community.

Alyce Martinمشاهده پروفایل

عضو هیئت علمی

• Gastroenterology
• Endocrinology
• Metabolism
• +۴ مورد دیگر

Alyce Martin is a Senior Research Fellow at Flinders University within the College of Medicine and Public Health and a Full Member of the Flinders Health and Medical Research Institute. Her research focuses on the functional biology of enteroendocrine cells, particularly serotonin-producing enterochromaffin (EC) cells, exploring how these cells interact with dietary nutrients, bacteria, and environmental factors to influence gut function, metabolism, fat storage, and gut-brain signaling. Education: Ph.D. in Medicine (2018): The role of enterochromaffin cells as sensors in the gastrointestinal lumen B.Sc. with First Class Honours (2012) B. Medical Science (2011), Major: Biochemistry and Medicinal Chemistry Her research interests span gut endocrinology, microbiome interactions, metabolic regulation, and the molecular mechanisms linking gut physiology to systemic health. Recent work highlights the microbiome's role in gut hormone secretion and the impact of SARS-CoV-2 infection on gut serotonin pathways. Notable grants include an ARC DECRA Fellowship ($468,582), NHMRC Ideas Grant ($1.1M), and multiple seed grants from Flinders University. Her awards include the 2021 Millennium Science Spatial Pioneers Fellowship and Flinders University Early Career Alumni Award. Grants and Funding: ARC Discovery Early Career Researcher Award (2022-2024) NHMRC Ideas Grant (2022-2026) Flinders Foundation Health Seed Grant (2020-2021) Dr. Martin collaborates internationally on gut microbiome studies and has presented at conferences such as the Little Brain Big Brain Symposium. She is affiliated with the Flinders Health and Medical Research Institute and maintains an active research group focused on translational gut biology.

Yi Linمشاهده پروفایل

استاد

• Cancer Immunotherapy
• Cell Therapy
• Hematology
• +۱۲ مورد دیگر

Yi Lin, M.D., Ph.D., is a Professor of Medicine and Assistant Professor of Oncology at Mayo Clinic, with primary and joint appointments in the Department of Internal Medicine, Division of Hematology, and the Department of Laboratory Medicine and Pathology, Division of Experimental Pathology and Laboratory Medicine. She is the Enterprise Leader for Cancer Regenerative Medicine, Biotherapeutics, and Biomanufacturing at the Mayo Clinic Comprehensive Cancer Center, Rochester, Minnesota. Education: BS in Chemical Engineering, University of Minnesota Ph.D. in Biomedical Engineering, University of Minnesota MD, Northwestern University Feinberg School of Medicine Residency and Fellowship, Mayo Clinic College of Medicine Dr. Lin is a hematologist and oncologist specializing in lymphoma, multiple myeloma, and cell therapy. Her research is centered on cancer immunotherapy, with a focus on CAR T-cell therapies, cancer vaccines, biomarkers of response and toxicity, and bioprinted tumor models. Her work has directly contributed to FDA approvals of CAR-T therapies such as Yescarta, Abecma, and Carvykti. She employs gene-editing tools and translational research to improve the safety and efficacy of next-generation immunotherapies. Analysis of her recent publications reveals a strong emphasis on clinical and translational immunotherapy, particularly in hematologic malignancies. Her work spans clinical outcomes in CAR-T therapy, biomarker discovery, resistance mechanisms involving myeloid cells, and innovative bioprinting models for drug testing. Her research integrates clinical data with laboratory science to develop personalized, risk-adapted treatment strategies. Scientific Awards: New Investigator Award, Mayo Clinic Department of Medicine (2017) NIH Loan Repayment Program (2012, 2007) AFLAC Scholar-in-training Award, AACR (2008) J. Thomas Livermore Award, University of Minnesota (2001) Merit-based Travel Awards, American Society of Hematology (2000, 1998) Dr. Lin has served as principal investigator on numerous NIH-funded and industry-sponsored clinical trials. She mentors research teams and collaborates nationally and internationally with organizations such as the International Myeloma Working Group, SITC, and BMT CTN. Her leadership roles include chairing the Cell Therapy Cross-Disciplinary Group and co-chairing immunotherapy committees. She is actively involved in developing clinical guidelines and advancing cellular therapy standards. Labs and Teams: Dr. Lin leads a multidisciplinary research team focused on cancer immunology and cellular therapy within the Mayo Clinic Center for Regenerative Medicine and the David F. and Margaret T. Grohne Cancer Immunology and Immunotherapeutics Program. Her lab integrates clinical trial data with translational research to innovate safer and more effective cancer treatments.

Nathan Shererمشاهده پروفایل

استاد

• Molecular Virology
• HIV-1 Biology
• Virus-Host Interactions
• +۱۲ مورد دیگر

Nathan Sherer is a Professor in the Department of Medical Microbiology and Immunology at the University of Wisconsin–Madison, with affiliations in the Bacteriology Department and the UW Carbone Cancer Center. His research integrates live-cell imaging and biochemical approaches to study virus-host interactions, focusing on HIV-1, Hepatitis B virus (HBV), and Human Papillomavirus (HPV). Institution: University of Wisconsin–Madison School: School of Medicine and Public Health Department: Department of Medical Microbiology and Immunology Additional Affiliation: UW Carbone Cancer Center Nathan Sherer earned his BA in Biology from Grinnell College in 1997, followed by a PhD in Microbiology from Yale University in 2006. He completed postdoctoral training at King’s College London before establishing his independent research program at UW-Madison. Dr. Sherer's research centers on the molecular virology of retroviruses, particularly HIV-1. His lab investigates how viral particles assemble and spread through host cells, with a focus on the post-transcriptional journey of HIV-1 genomic RNAs (gRNAs) from the nucleus to the plasma membrane. They utilize cutting-edge live-cell fluorescence microscopy, genetic manipulations, and biochemical assays to dissect virus-host interactions. Key areas include viral RNA transport, ribosomal frameshifting, virological synapse formation, and the role of host proteins in viral replication. The lab has expanded its scope to include HBV and HPV, exploring mechanisms of genome packaging, capsid trafficking, and viral oncogenesis. The recent publications highlight a strong emphasis on imaging technologies, RNA biology, and host factor identification. Articles span super-resolution microscopy development, single-cell analysis of viral gene expression, and proteomic mapping of viral RNA interactomes. Collectively, the work reveals sophisticated strategies viruses use to hijack cellular machinery, offering insights for novel antiviral therapies. Dr. Sherer mentors a dynamic team of graduate students and postdoctoral researchers from programs such as Molecular and Cellular Pharmacology, Cancer Biology, and Cellular and Molecular Biology. His alumni have pursued successful careers in academia, biotechnology, and pharmaceutical research. While no specific scientific awards are listed, his consistent high-impact publications reflect significant contributions to virology. The lab also benefits from collaborative grants and institutional support, enabling advanced imaging and proteomic studies. Dr. Sherer leads an active research laboratory with ongoing projects in HIV-1, HBV, and HPV virology. The team employs a multidisciplinary approach, combining molecular biology, imaging, and biochemistry to understand viral replication mechanisms. Lab members include senior scientists, postdocs, and graduate students working on various aspects of viral assembly, RNA regulation, and host interactions.

Chris Rockمشاهده پروفایل

استاد

• Plant Molecular Genetics
• Abscisic Acid Signaling
• Stress Signal Transduction
• +۷ مورد دیگر

Chris Rock is a Professor in the Department of Biological Sciences at Texas Tech University, College of Arts and Sciences. His research focuses on plant molecular genetics, particularly abscisic acid signaling, stress response, and small RNA biology. He leads a research group active in both fundamental and applied plant science, with projects involving CRISPR/Cas9 engineering of crops for improved agronomic traits. Ph.D., Michigan State University (1991) A.B., Molecular Biology, U.C. Berkeley (1985) Dr. Rock's research interests center on understanding the molecular mechanisms of plant stress adaptation, especially drought and salinity. His work investigates ABA signaling pathways, microRNAs, and non-coding RNAs in model systems like Arabidopsis and crops such as cotton and grapevine. He has pioneered the use of transient expression systems and genetic engineering to dissect gene function and improve crop resilience. The trend in his recent publications reflects a strong focus on gene regulation via small RNAs, transcription factors (e.g., ABI3, ABI5, RAV), and their roles in stress response and development. His work bridges molecular biology with agricultural applications, particularly in enhancing water use efficiency, fiber quality, and nutraceutical production. Scientific Awards: No specific awards listed in the provided text. Dr. Rock actively mentors graduate students and offers research assistantships and postdoctoral opportunities. His lab engages in collaborative and interdisciplinary research, supported by publications in high-impact journals. He has contributed to major reference works such as Encyclopedia of Life Sciences and Arabidopsis (Cold Spring Harbor). His lab provides training in molecular biology, genomics, and plant biotechnology. Dr. Rock leads research initiatives in plant stress biology and functional genomics, with active projects on transgenic cotton, small RNA pathways, and ABA signaling. His team utilizes advanced techniques including transcriptome profiling, CRISPR/Cas9, and physiological assays to explore gene function and crop improvement strategies.

Sandra Pohlمشاهده پروفایل

استاد

• Lysosomal storage disorders
• Mucolipidosis type II and III
• Osteogenesis imperfecta
• +۵ مورد دیگر

Prof. Dr. Sandra Pohl is a full Professor at the University Medical Center Hamburg-Eppendorf (UKE), affiliated with the Department of Osteology and Biomechanics. Her research focuses on lysosomal storage disorders, particularly mucolipidosis types II and III, and their systemic effects on bone, cartilage, kidney and the central nervous system. She employs mouse models, human genetic studies and translational approaches to dissect disease mechanisms and develop therapeutic strategies. Education & Training No specific educational details provided in the source material; only the academic title "Prof. Dr. (PhD)" is listed. Research Interests Prof. Pohl’s work centers on: Molecular pathology of mucolipidosis type II (I-cell disease) and type III (pseudo-Hurler polydystrophy). GlcNAc-1-phosphotransferase biology and its role in lysosomal enzyme targeting. Skeletal manifestations of lysosomal storage disorders, including osteopenia, cartilage degeneration and dysostosis multiplex. Neurocognitive outcomes and CNS imaging in mucolipidosis patients. Enzyme replacement therapy design and evaluation in pre-clinical mouse models. Proteostasis, autophagy and ubiquitin-proteasome system interactions in disease pathogenesis. Publication Trends Between 2020 and 2024, Prof. Pohl has published extensively on the intersection of lysosomal dysfunction and skeletal/renal/neurological pathology. Her recent articles emphasize: Genotype–phenotype correlations in GNPTAB/GNPTG variants. Translational mouse models recapitulating human mucolipidosis. Multi-omics profiling (proteomics, imaging, metabolomics) to uncover disease biomarkers. Interdisciplinary studies linking basic cell biology to clinical manifestations. Research Support & Collaborations Prof. Pohl currently leads or co-leads the following initiatives: SFB 877, Teilprojekt B03: “Proteolysis-ver” (exact title abbreviated in source) – a collaborative research center funded by the German Research Foundation (DFG). Cross-institutional consortia involving nephrologists, neurologists, geneticists and imaging specialists across Germany and internationally. Laboratory & Core Facilities Her team utilizes state-of-the-art core facilities provided by UKE, including: Transgenic mouse core Advanced imaging and microscopy Mass-spectrometry-based proteomics High-throughput sequencing and bioinformatics platforms

Fabien Crausteمشاهده پروفایل

پژوهشگر

• Biomathematics
• Mathematical Immunology
• Delay Differential Equations
• +۴ مورد دیگر

Fabien Crauste is a Director of Research at CNRS, affiliated with MAP5 UMR 8541 at the University of Paris Cité. His work bridges applied mathematics and biomedical research through multi-scale modeling. Math Bio Santé Thematic Network Director Organizer of Modeling, Analysis, Simulations working group Co-organizer of mathematical modeling in life sciences seminar Member of PEPR Maths-Vives Program Committee Active in AMIES and MAP1.5 environmental initiatives Research focuses on mathematical immunology , delay differential equations , and cell population dynamics with applications to CD8 T cell responses, B cell differentiation, and diseases like chronic lymphocytic leukemia and atopic dermatitis . Special emphasis on stochastic modeling and inter-individual variability in immune responses. Current projects include AI4scMED (multiscale AI for precision medicine), DCComm (dendritic-T cell communication), and Digi-DermA (dermatitis modeling). Supervises multiple postdocs and PhD students on these topics. Contributions include developing the Simuscale framework for multi-cell modeling and analyzing erythropoiesis dynamics and germinal center B cell differentiation .

Elise Grosjeanمشاهده پروفایل

استادیار

• Fluid Mechanics
• Partial Differential Equations (PDEs)
• Numerical Analysis
• +۶ مورد دیگر

Elise Grosjean is an Assistant Professor in Applied Mathematics at ENSTA Paris. Her research focuses on fluid mechanics, partial differential equation analysis, numerical schemes, reduced order methods, inverse problems, and optimal transport. Education: PhD in Applied Mathematics (2022, Sorbonne Université), Master in Mathematics of Modeling (2018, UPMC), Engineer School in Applied Mathematics and Computer Science (2018, Polytech-Paris UPMC), Bachelor in Fundamental Mathematics (2015, UPMC) Her research integrates finite element/volume methods, programming languages, and numerical simulation of parameterized models from physics and biology. She actively develops reduced basis methods and applies them to tissue regeneration and fluid dynamics problems. Recent publications highlight her work on meniscus tissue regeneration modeling (2024), error estimates in two-grid reduced basis methods (2024), and numerical simulations using FreeFem++ for 3D bioreactor models and back-and-forth nudging algorithms for wave equations (2023-2024). These works span biomedical engineering, computational mathematics, and inverse problem solving. She has taught courses on differential-algebraic equations at TU Kaiserslautern and contributed to teaching at ENSTA Paris, Sorbonne Université, and ENSAE. Her technical expertise includes Python, C++, FreeFem++, and model order reduction frameworks. Elise is affiliated with INRIA-Saclay (current postdoc), RPTU Kaiserslautern (2022-2023), and the Jacques-Louis Lions Laboratory (2018-2022). She also explores intersections between mathematics and art in her creative practice.

• Signal Transduction
• Oncology
• Biochemistry
• +۵ مورد دیگر

Manfred Jücker is a Professor at the Institute of Biochemistry and Signal Transduction within the University Medical Center Hamburg-Eppendorf (UKE) . His research focuses on phosphoinositide signaling pathways , particularly the PI3K/AKT/mTOR network , and their roles in cancer progression and leukemia pathogenesis . Jücker investigates how Akt isoforms differentially regulate metastasis , drug resistance , and cell survival in tumors like hepatocellular carcinoma , breast cancer , and colorectal cancer . Recent publications highlight his work on SHIP1 phosphatase in hematopoietic malignancies , targeted kinase inhibition in AML , and metabolic reprogramming via AKT isoform regulation . His team uses in vitro tumor models , xenotransplantation , and phosphoproteomics to explore novel therapeutic approaches. Jücker collaborates extensively with clinicians and researchers in oncology , immunology , and translational medicine , contributing to drug development strategies and personalized cancer therapy . Key projects include reducing animal experiments through in vitro tumoroids and analyzing CYTL1 as a treatment target in elderly AML patients.

Tobias Allanderمشاهده پروفایل

عضو هیئت علمی

• Virology
• Molecular Epidemiology
• Viral Evolution
• +۳ مورد دیگر

Tobias Allander is an Adjunct Senior Lecturer at Karolinska Institutet, affiliated with the Department of Microbiology, Tumor and Cell Biology. He also holds a position as Senior Consultant at the Department of Clinical Microbiology, Karolinska University Hospital. His research focuses on HIV genetic variation, evolution, and resistance; enterovirus evolution and spread; and pandemic preparedness, particularly for coronaviruses. He leads a research group that develops novel methods for estimating HIV infection times using next-generation sequencing (NGS) and biomarkers, supported by NIH, VR, and ALF grants. His work spans viral discovery, molecular epidemiology, and clinical virology, with a strong emphasis on respiratory and bloodborne viruses. University: Karolinska Institutet Department: Department of Microbiology, Tumor and Cell Biology Clinical Affiliation: Karolinska University Hospital, Clinical Microbiology Tobias Allander's research interests include: Virology Molecular Epidemiology Viral Evolution Pandemic Preparedness Next-Generation Sequencing (NGS) Clinical Microbiology His publications highlight expertise in viral discovery, particularly human bocavirus and polyomaviruses, and advanced NGS applications. Recent articles investigate SARS-CoV-2 variant transmission, HIV incidence estimation, and enterovirus D68 outbreaks. His group contributes to Sweden's pandemic surveillance efforts, including the SciLifeLab program, and maintains collaborations with Los Alamos National Laboratory and Stockholm University. As an advisor, Tobias Allander supervises PhD candidates, including Amanj Bajalan. He has not received any explicitly mentioned scientific awards in the provided texts. His clinical work at Karolinska University Hospital involves diagnostic studies and virus discovery in pediatric and immunocompromised populations.

• Cancer Biology
• Molecular Oncology
• Protease Biology
• +۹ مورد دیگر

John Hooper is a prominent researcher in cancer molecular biology, affiliated with the Faculty of Science and the School of Biomedical Sciences at Queensland University of Technology. His work centers on the role of proteases, particularly serine proteases and CDCP1, in cancer progression and therapy. With a publication record spanning over two decades, he has contributed significantly to understanding proteolytic signaling in ovarian, prostate, and colorectal cancers. His research interests include Cancer Biology, Protease Signaling, CDCP1, Kallikrein-Related Peptidases, and Targeted Cancer Therapy . He has extensively studied how proteases like KLKs and membrane serine proteases regulate cell signaling via PARs and contribute to tumor dissemination. A major focus has been on CDCP1, a cell surface glycoprotein that promotes metastasis and is now being explored as a therapeutic and imaging target. The recent publications (2020–2025) demonstrate a strong trend toward translational research, including the development of anti-CDCP1 immuno-conjugates, imaging tracers, and metabolic targeting in ovarian and breast cancers. His work increasingly integrates preclinical models, molecular imaging, and combination therapies to overcome drug resistance. John Hooper has collaborated with leading researchers in oncology and molecular biology. While no formal awards are listed, his work has been published in high-impact journals such as Oncogene , Clinical Cancer Research , and Theranostics . He has contributed to major collaborative projects, including the PRACTICAL consortium on prostate cancer genetics. He has mentored or collaborated with numerous researchers, though specific students are not listed. His lab or research group appears to focus on protease biology and cancer signaling pathways, often using biochemical, cellular, and in vivo models to validate therapeutic targets.

Ron D. Jachimowiczمشاهده پروفایل

دانشیار

• DNA repair
• Genome stability
• Aging
• +۴ مورد دیگر

Ron D. Jachimowicz is a Max Planck Research Group Leader specializing in DNA repair mechanisms and their relationship to aging and cancer development. As a Privatdozent (equivalent to Associate Professor), he leads an independent research group at the Max Planck Institute focused on understanding how DNA repair pathways impact genome stability, aging processes, and cancer progression. His work bridges basic science with clinical applications, particularly in lymphoma research. Dr. Jachimowicz's research centers on the critical relationship between DNA repair mechanisms and aging. His group investigates defects in DNA repair pathways in patients with genome instability syndromes and in patients suffering from mantle cell lymphoma, utilizing an interdisciplinary approach that combines biochemistry, cell biology, computational biology, and mouse genetics. Key research areas include the role of UBQLN4 in DNA repair pathway choice, ATM signaling in DNA damage response, and the connection between genome maintenance defects and age-related diseases. His work has revealed important mechanisms linking DNA repair deficiencies to cancer development, particularly in lymphomas, and has identified potential therapeutic targets for cancer treatment. Analysis of Dr. Jachimowicz's publication record shows a consistent focus on DNA repair mechanisms and their implications for cancer biology. His research demonstrates how defects in DNA repair pathways lead to genome instability, which drives both aging processes and cancer development. Recent publications highlight his work on UBQLN4's role in DNA repair pathway choice, ATM signaling in immune surveillance of lymphoma, and the development of targeted therapies for cancers with specific DNA repair deficiencies. His interdisciplinary approach combines molecular biology, mouse models, and clinical data to translate basic discoveries into potential therapeutic strategies. Scientific Awards: Theodor Frerichs Prize from the German Society for Internal Medicine (DGIM), 2020 Dr. Jachimowicz serves as principal investigator for multiple significant research grants and advises doctoral students in his laboratory. His research is supported by prestigious funding including the German Research Foundation (DFG) Research Unit FOR5504 (2023-2026), Collaborative Research Center SFB1530 (2022-2025), and the Research Network CANTAR from the Ministry of Culture and Science of North Rhine-Westphalia (2022-2026). He also serves as co-speaker for the Else Kröner Research College on Clonal Evolution in Cancer. His doctoral student Julia Hansen received a scholarship from the German Academic Scholarship Foundation in 2022. Dr. Jachimowicz leads a dynamic research laboratory focused on DNA repair mechanisms and their relationship to aging and cancer. His group employs a comprehensive interdisciplinary approach that integrates biochemical, cellular, computational, and genetic techniques to investigate how defects in DNA repair pathways contribute to genome instability syndromes and cancer development. The lab's work has particular relevance for understanding mantle cell lymphoma and developing targeted therapeutic interventions based on DNA repair deficiencies.

• Proteomics
• Systems Biology
• Protein Methylation
• +۵ مورد دیگر

Marc Wilkins is a Professor of Systems Biology at the University of New South Wales (UNSW) School of Biotechnology and Biomolecular Sciences. He currently serves as Deputy Dean (Research and Enterprise) for the Faculty of Science and leads the UNSW node of the $35M ARC Centre of Excellence in Mathematical and Statistical Frontiers (MACSYS). Previously, he directed the Ramaciotti Centre for Genomics (2011-2022) and the NSW Systems Biology Initiative. His research focuses on: Protein methylation networks and their regulatory functions in eukaryotic cells Large-scale analysis of protein-protein interactions using crosslinking mass spectrometry (XL-MS) Genomics and transcriptomics with expertise in next-generation sequencing Systems biology approaches combining proteomics, bioinformatics, and molecular biology He has published over 260 peer-reviewed papers and pioneered the concept of the 'proteome' in 1994. His publications demonstrate consistent focus on proteomics technology development, post-translational modifications, and multi-omics integration across diverse biological systems. Recent work emphasizes structural proteomics, methylation networks, and conservation genomics. Major Awards: Doctor of Science (D.Sc.) from UNSW (2017) ASBMB Beckman Coulter Discovery Science Award (2012) Elected Council Member of Human Proteome Organisation (2009-2024) He has supervised 38 honours students (6 University Medalists), 16 PhD students, and 5 Master's students. His ARC-funded laboratory focuses on proteomics and systems biology. Major grants include leadership in the $35M MACSYS Centre of Excellence and previous direction of genomics facilities funded by NCRIS, ARC LIEF, and NSW Government schemes. He co-founded two biotechnology companies: Tyrian Diagnostics (proteomic diagnostics) and Regeneus (regenerative medicine), both listed on the ASX. His team maintains expertise in cutting-edge proteomic and genomic technologies with strong industry collaborations.

Jessica Marمشاهده پروفایل

استاد

• Bioinformatics
• Single-cell Biology
• Stem Cell Biology
• +۳ مورد دیگر

Professor Jessica Mar is a Professorial Research Fellow at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at the University of Queensland. Her research focuses on developing bioinformatics methods to understand regulatory processes in human diseases, particularly leveraging single-cell RNA-sequencing to analyze cellular heterogeneity in contexts like cancer, aging, and stem cell biology. Key areas include modeling gene expression variability, analyzing transcriptomic data, and developing statistical frameworks for omics integration. She has led projects funded by grants such as the Georgina Sweet Award and ARC Future Fellowships. Her work spans computational approaches to cancer heterogeneity, senescence mechanisms in stem cells, and the impact of senolytic therapies on aging. Recent studies include applications of single-cell technologies to brain organoids and breast cancer metastasis. Awards include recognition for contributions to quantitative biomedical science and stem cell research. She collaborates widely, mentoring students in computational biology, stem cell biology, and systems biology. Publications highlight her contributions to understanding tumor heterogeneity, epigenetic dynamics, and the interplay between mechanics and cell reprogramming. Her lab’s work integrates machine learning with experimental biology, addressing challenges in data analysis for single-cell and spatial omics. Current projects include biomarker discovery for hypoxic-ischemic encephalopathy and developing optimal transport models for cancer progression analysis.

Gabrielle Belzمشاهده پروفایل

استاد

• Immunology
• Cellular immunology
• Mucosal immunity
• +۴ مورد دیگر

Professor Gabrielle Belz is an ARC Australian Laureate Fellow at The University of Queensland's Frazer Institute within the Faculty of Health, Medicine and Behavioural Sciences. She holds a PhD and multiple advanced degrees in veterinary science and immunology. Her research focuses on understanding protective immunity, cellular differentiation, and innate immune cell development, particularly in mucosal defenses against pathogens like influenza and herpesviruses. Belz pioneered systems for tracking virus-specific T cells and identified critical roles for CD4 T cell help in antiviral responses. Her work integrates multiparameter flow cytometry, systems biology, and in vivo models to study immune pathways in health and disease. Education: Bachelor of Veterinary Biology, The University of Queensland Bachelor (Honours) of Veterinary Science, The University of Queensland Doctor of Philosophy, The University of Queensland Doctoral Diploma, The University of Queensland Research Interests: Mechanisms of protective immunity against respiratory and gastrointestinal pathogens Role of innate lymphoid cells (ILCs) and T cells in mucosal immunity Immune responses to chronic infections and tumours Epithelial- immune cell cross-talk in barrier integrity Spatial biology and multi-omics approaches to study immune landscapes Awards & Honours: Arc Laureate Fellowship (2024) Gottschalk Medal (Australian Academy of Science) Wellcome Trust Overseas Fellowship HHMI International Research Scholar Award NHMRC Elizabeth Blackburn Fellowship Grants & Funding: ARC Australian Laureate Fellowships (2025-2029) NHMRC MRFF grants for lung cancer and immunotherapy research Cure Cancer Early Career Research Grants (2024-2026) Her laboratory actively supervises PhD candidates exploring mucosal immunity, vaccine development, and innate immune cell metabolism. Belz collaborates widely, leveraging cutting-edge platforms like spatial multi-omics to advance translational immunology.