جست‌وجوی استاد و پژوهشگر

Geoffrey Payneمشاهده پروفایل

استاد

• Cardiovascular Physiology
• Immunology
• Microcirculation
• +۳ مورد دیگر

Dr. Geoffrey Payne is the President and Vice Chancellor of the University of Northern British Columbia, as well as a Professor within the Division of Medical Sciences. He holds academic appointments in the Northern Medical Program and oversees administrative leadership roles. His academic background includes a PhD in Cardiovascular and Renal Physiology, an MSc in Neuroscience and Pharmacology, and a BSc in Behavioural Neuroscience, all from Memorial University of Newfoundland. Previously, he was a Postdoctoral Fellow at Yale University's John B. Pierce Laboratory, specializing in Microcirculation research. Dr. Payne’s research focuses on cardiovascular physiology, immunology, and lymphatic systems, with notable contributions to understanding microvascular dysfunction in aging, inflammatory responses, and structural valve degeneration in cardiac devices. His work integrates intravital microscopy and translational approaches to study disease mechanisms. He has authored or co-authored over 145 publications, emphasizing innovations in transcatheter valve therapies and microcirculatory biology. His recent studies investigate the impact of bioprosthetic valve remodeling, smoking effects on coronary vasculature, and Alzheimer’s-related microvascular changes. Dr. Payne also advocates for rural healthcare delivery and medical education reform, contributing to interdisciplinary medical curricula and interprofessional education models. As an administrator, he champions academic innovation and community engagement, aligning research priorities with regional healthcare needs in Northern British Columbia.

Abass Alaviمشاهده پروفایل

استاد

• Nuclear Medicine
• PET Imaging
• SPECT/CT Hybrid Imaging
• +۳ مورد دیگر

Abass Alavi, MD, is a Professor of Radiology at the Hospital of the University of Pennsylvania and Associate Director of the Center for the Study of Aging at the University of Pennsylvania. He specializes in nuclear medicine and radiology, with a focus on imaging techniques such as PET, SPECT/CT, and their clinical applications in oncology, diabetes, and inflammatory diseases. His research spans lymphatic mapping, diagnostic imaging advancements, and the integration of imaging with therapeutic strategies. Education: M.D. (Medicine), University of Tehran School of Medicine, 1964. Post-Graduate Training: Residencies in Medicine and Radiology, Fellowships in Hematology and Nuclear Medicine. Research Interests: Dr. Alavi’s work emphasizes the development and clinical utility of hybrid imaging modalities (e.g., SPECT/CT and PET/CT). His studies include lymph node localization in breast cancer, CT metrics for COPD, and FDG-PET imaging in thyroid lymphoma. He also investigates diabetes-related complications, particularly foot pathologies, and functional imaging of inflammatory disorders. Publications: His 2009 publications highlight advancements in imaging techniques, including partial volume correction in PET and the palliative effects of lung surgeries. His work bridges diagnostic innovation with clinical outcomes, emphasizing multimodal approaches to disease management. Awards: No specific awards listed. Advising & Grants: No explicit details on grants or advisees provided. His contributions focus on collaborative research in imaging and clinical trials. Labs/Teams: Associated with the Center for the Study of Aging and the Perelman School of Medicine’s Radiology Department.

Raj Kishoreمشاهده پروفایل

استاد

• Cardiovascular Repair and Regeneration
• Stem Cell Therapy
• Extracellular Vesicles and Exosomes
• +۷ مورد دیگر

Raj Kishore is a Professor at the Lewis Katz School of Medicine at Temple University, where he holds appointments in the Department of Cardiovascular Sciences and the Department of Medicine. He serves as Chair and Professor at the Lemole Center for Integrated Lymphatics and Vascular Research and is a key member of the Aging + Cardiovascular Discovery Center. His work bridges molecular cardiology, regenerative medicine, and vascular biology. Dr. Kishore earned his PhD and MD from the University of Lucknow, India, in 1995 and 1988, respectively, and completed his undergraduate studies there in 1986. His research has been continuously funded and published in top-tier journals. His research interests are centered on cardiovascular repair mechanisms after myocardial infarction. He investigates the therapeutic potential of stem cells, stem cell-derived exosomes, noncoding RNAs (including microRNAs and circular RNAs), and epigenetic modifications. A major focus is on developing cell-free therapies using exosomes as alternatives to whole-cell transplantation. His lab also studies diabetes-induced endothelial dysfunction, inflammation, and the impact of aging and gender on cardiac repair. He explores gene and mRNA-based therapeutics to enhance cardiomyocyte renewal. Analysis of his recent publications reveals a strong trend toward exosome-based therapies, epigenetic regulation, and metabolic reprogramming in stem cells for cardiac repair, particularly in diabetic conditions. His work frequently involves molecular signaling pathways such as STAT3, E2F1, VEGF, and TNF-alpha, and he has contributed significantly to understanding how microenvironmental factors influence regenerative capacity. Dr. Kishore has made significant scientific contributions, though specific awards are not listed in the provided text. His leadership is evident through his role as Chair and his extensive collaborative network. He actively mentors students and postdoctoral researchers, many of whom have become co-authors on high-impact publications. His lab is involved in grant-funded research exploring novel regenerative strategies. While specific grants are not listed, his publication record suggests sustained NIH or equivalent funding. His research is conducted within the Lemole Center for Integrated Lymphatics and Vascular Research and the Aging + Cardiovascular Discovery Center, both at Temple University, where he leads a multidisciplinary team focused on translational cardiovascular discovery.

Deborah Strokaمشاهده پروفایل

استاد

• Molecular Biology
• Hepatology
• Cancer Research
• +۳ مورد دیگر

Prof. Deborah Stroka is a Professor and Head of Research Group at the Department of Biomedical Research (DBMR), Faculty of Medicine, University of Bern, with dual affiliation to the Department of Visceral Surgery and Medicine at Bern University Hospital. Her research bridges molecular mechanisms of liver disease, cancer biology, and infectious disease pathogenesis through the Multidisciplinary Center for Infectious Diseases (MCID). Her primary research focuses on DNA replication stress in metabolic dysfunction-associated steatohepatitis (MASH), tight junction protein functions (particularly claudin-3) in hepatic barrier integrity, bacterial ATP-mediated inflammation in sepsis, and nanoplastic biodistribution. She investigates tumor budding mechanisms in colorectal cancer, MET receptor signaling in DNA damage response, and lymphatic regulation in gut-liver axis pathologies using advanced spatial transcriptomics and lipidomics approaches. Recent publications reveal strong emphasis on molecular intersections between infection, metabolism, and tissue repair, with innovative techniques in X-ray fluorescence imaging for nanotoxicology and Skyline-based lipid isomer analysis. Recurring themes include bacterial translocation impacts on liver regeneration, replication stress in aging, and therapeutic targeting of fibrosis pathways. As Head of Research Group within MCID, she leads interdisciplinary teams developing models for abdominal sepsis, radiation-induced liver disease, and orthotopic cancer systems while pioneering analytical methods for nanoplastics and lipid isomers in disease contexts.

Marina Venero Galanternikمشاهده پروفایل

استادیار

• Developmental Biology
• Neuroscience
• Lymphatic System
• +۳ مورد دیگر

Marina Venero Galanternik is an Assistant Professor at the University of Utah 's Department of Human Genetics. Her research focuses on meningeal development, lymphatic systems, and neurovascular interactions using zebrafish as a model organism due to their optical accessibility for high-resolution imaging. B.S. from Universidad Nacional Agraria La Molina Ph.D. from University of Utah Her work investigates meningeal dysfunction in diseases like meningitis and age-related neurodegeneration, leveraging zebrafish's transparent skull to study cellular and molecular mechanisms. Recent publications highlight anatomical discoveries, lymphatic pathophysiology, and innovative imaging techniques. Key collaborations include research with Dr. Brant M. Weinstein's lab, focusing on: Developmental pathways in meningeal and lymphatic systems Non-cell-autonomous signaling in collective cell migration Comparative neuroanatomy between zebrafish and mammals Contact: marina.venero@genetics.utah.edu

Nancy J. Ruschمشاهده پروفایل

استاد

• Calcium Channels
• Potassium Channels
• Hypertension
• +۳ مورد دیگر

Nancy J. Rusch is a Distinguished Professor and Chair of the Department of Pharmacology and Toxicology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. She holds a Ph.D. from the Mayo Clinic (1983). Her research focuses on ion channel abnormalities in hypertension, particularly calcium and potassium channels in vascular muscle cells, with a goal to identify channel-based therapies for systemic and pulmonary hypertension. She employs molecular, cellular, and in vivo techniques in her investigations. Recent research grants include NIH R01 grants (e.g., R01 HL097107), AHA Predoctoral Fellowships, and collaborations with institutions like PhRMA and the Arkansas CCTR. She has advised students such as Shrum, Stolarz AJ, and Detweiler ND, contributing to studies on lymphatic dysfunction, renal transplantation, and channel therapies. Key areas of study include mitochondrial BK channel roles in renal preservation, doxorubicin-induced lymphostasis, and leptin’s impact on obesity-related hypertension. Her work bridges basic science with translational medicine, aiming to improve vascular health outcomes.

• Drug Delivery
• Lymphatic Biology
• Pharmacokinetics
• +۴ مورد دیگر

Dr. Natalie Trevaskis is an Associate Professor at Monash University's Faculty of Pharmacy and Pharmaceutical Sciences and Head of the Lymphatic Medicine Laboratory at the Monash Institute of Pharmaceutical Sciences. Her work focuses on lymphatic dysfunction in diseases like arthritis, pancreatitis, and metabolic disorders, and developing lymph-targeted drug delivery systems. She holds an H-index of 27 and over 65 publications in top journals, including Nature and Nature Metabolism. Dr. Trevaskis has secured patents for lipid prodrugs licensed to Puretech Health and Boehringer Ingelheim. Education: BPharm (Gold Medal, 2001), PhD (Mollie Holman Medal, 2006), Monash University. Research Interests: Lymphatic biology, drug delivery systems (liposomes, lipoproteins), metabolic diseases, and immunology. Her lab includes 2 postdocs, 7 PhD students, and 2 honours students. She has supervised 13 completions, with students winning international awards. Dr. Trevaskis is a sought-after speaker, presenting at conferences like the International Lymphatic Forum and Gordon Research Conferences. Teaching Roles: Unit coordinator for PHR1022/PHR2021 in Master of Pharmacy programs, lecturing on drug delivery and pharmacokinetics. Her professional roles include serving on the MIPS Animal Ethics Committee, editorial boards for Pharmaceutical Research and Journal of Pharmaceutical Science, and leading initiatives like the Melbourne Lymphatic Symposium since 2016.

• Lung Transplantation
• Respiratory Diseases
• Thoracic Surgery
• +۴ مورد دیگر

Robin Vos serves as an Associate Professor at KU Leuven's Faculty of Medicine, where he is affiliated with the Department of Chronic Diseases and Metabolism and the Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE). He is also a member of Leuven.IRD - KU Leuven Institute for Rare Diseases and participates in institutional governance as a member of both the Council of the Faculty of Medicine and the Council of the Department of Chronic Diseases and Metabolism. Dr. Vos's research focuses primarily on lung transplantation, with particular expertise in chronic lung allograft dysfunction, lymphatic system involvement in transplantation, and the impact of donor/recipient aging on transplant outcomes. His work bridges clinical practice and laboratory research, with significant emphasis on improving graft acceptance and understanding the physiological changes following lung transplantation. Analysis of his recent publications reveals a strong concentration on practical clinical challenges in lung transplantation, including management of right ventricular function, handling complications like infarction, optimizing donor organ utilization (including from elderly donors), and addressing infection management in transplant recipients. His research increasingly incorporates advanced methodologies including computational modeling for disease understanding. Dr. Vos actively supervises numerous research projects, serving as principal investigator or co-investigator on grants extending through 2030, with particular focus on the OLYMPUS project investigating lymphatics in lung transplantation. His research portfolio demonstrates consistent funding and institutional support for his specialized work in pulmonary transplantation. Within the clinical and academic environment, Dr. Vos contributes to the Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), which appears to be a multidisciplinary research unit investigating various aspects of respiratory pathophysiology, transplantation, and surgical interventions. His work frequently involves collaboration with the University Hospital Leuven's transplant team.

• Stem Cell Biology
• Tissue Engineering
• Pediatric Surgery
• +۵ مورد دیگر

Prof. Paolo De Coppi is the Nuffield Chair and NIHR Professor of Paediatric Surgery at University College London (UCL), affiliated with the Great Ormond Street Hospital. He leads the Surgery Unit, Stem Cells & Regenerative Medicine Section within the Developmental Biology & Cancer Programme. His roles include President-Elect of the European Pediatric Surgical Association (EUPSA) and Fellow of the Academy of Medical Sciences. With expertise in congenital anomalies and regenerative medicine, his research focuses on stem cell therapies, organoids, and tissue engineering, including pioneering work with amniotic fluid stem cells and bioengineered organs like the trachea. Education: MD (1997), Medical Registrar (2002), PhD (2006) from the University of Padua, followed by training at Boston Children’s Hospital and Amsterdam’s Academic Medical Center. Research Interests: Development of fetal therapies, tissue-engineered organs (esophagus, trachea), organoid models for congenital defects (e.g., neural tube defects, Hirschsprung disease), and translational applications of stem cells. His work bridges basic science and clinical practice, emphasizing congenital anomaly repair and regenerative strategies. Publications & Impact: Over 350 peer-reviewed articles (h-index 65), including high-impact journals like Nature and The Lancet. Key contributions include first human trachea transplantation (2010) and novel organoid derivation methods from fetal fluids. He has secured £30M+ in grants and advises major journals like Stem Cell Translational Medicine . Awards: TIME 100 Health (2024) for stem cell innovation; first pediatric surgeon elected to the Academy of Medical Sciences (2020). Advising & Grants: Supervised 35+ PhD/research fellows. Leads multidisciplinary teams in fetal surgery (e.g., spina bifida repair models) and collaborates globally through networks like ERNICA. Labs/Teams: Head of UCL’s Stem Cells & Regenerative Medicine Section. Active in translational projects like decellularized organ repopulation and bioengineered tissues.

Walter Lee Murfeeمشاهده پروفایل

استاد

• Cell dynamics
• Microcirculation
• Angiogenesis
• +۴ مورد دیگر

Walter Lee Murfee is a Professor and Associate Chair for Undergraduate Studies in the J. Crayton Pruitt Family Department of Biomedical Engineering at the University of Florida’s Herbert Wertheim College of Engineering. His research focuses on microvascular dynamics, integrating in vivo, in vitro, and computational approaches to study angiogenesis, lymphangiogenesis, and neurogenesis. Dr. Murfee leads the Microvascular Dynamics Laboratory and has pioneered ex vivo models to investigate tumor microenvironment interactions and vascular regeneration. He holds a B.S. in Mechanical Engineering from MIT (1999) and a Ph.D. in Biomedical Engineering from the University of Virginia (2005). Education: B.S., Mechanical Engineering, Massachusetts Institute of Technology, 1999 Ph.D., Biomedical Engineering, University of Virginia, 2005 His research explores vascular patterning, bioengineering approaches for functional tissue engineering, and vascular dysfunction in aging, hypertension, and tumors. Key contributions include developing high-fidelity computational models of microvascular hemodynamics and novel bioprinting methods for vascularized tissues. Awards include the 2023 Service Excellence Award and 2019 Teaching Excellence Award from UF, as well as leadership roles in The Microcirculatory Society since 2016. Awards & Recognition: Service Excellence Award, 2023 Teaching Excellence Award, 2019 President, The Microcirculatory Society (2019–Present) Associate Editor, Microcirculation (2018–Present) His work bridges engineering and biology, addressing challenges in vascular health through interdisciplinary innovation. Current projects include studying aging-related vascular bioenergetics and lymphatic-blood plasticity. The lab collaborates on clinical translation via initiatives like MINDS (Mentoring for Innovative Design Solutions).

Riikka Martikainenمشاهده پروفایل

استاد پژوهشی

• Mitochondrial diseases
• Stem cell research
• Neurodegenerative diseases
• +۷ مورد دیگر

Riikka Martikainen serves as a Research Director at the A.I. Virtanen Institute for Molecular Sciences within the Faculty of Health Sciences at the University of Eastern Finland. Her research program focuses on mitochondrial diseases, stem cell modeling, and neurodegenerative disorders, with particular expertise in Parkinson's disease mechanisms and mitochondrial DNA mutations. She leads significant research initiatives including the Neuro-Innovation project (2021-2026) and the NOVEL MSCA Postdoctoral Programme (2024-2029), demonstrating her leadership in both specific research domains and broader capacity-building efforts. Dr. Martikainen's research centers on understanding mitochondrial dysfunction in disease contexts using induced pluripotent stem cell (iPSC) technology to model conditions like Parkinson's disease, progressive myoclonic epilepsy, and mitochondrial disorders. Her laboratory investigates how mtDNA mutations affect cellular function across various tissue types, with particular attention to neuronal and cardiac cells. She explores the interplay between mitochondrial dysfunction, metabolic alterations, and neurodegenerative processes, seeking to identify potential therapeutic targets and develop disease-specific cellular models. Analysis of her recent publications reveals a strong emphasis on developing and characterizing disease-specific iPSC lines, investigating mitochondrial heteroplasmy dynamics, and examining cellular responses to mitochondrial dysfunction. Her work spans from basic mechanisms of mitochondrial DNA maintenance to translational applications in disease modeling and potential therapeutic interventions, with particular focus on astrocyte contributions to Parkinson's pathology, mitochondrial mutation effects on cellular metabolism, and innovative approaches to modulate mtDNA heteroplasmy. Dr. Martikainen's laboratory utilizes advanced techniques including iPSC derivation and differentiation, mitochondrial function assays, calcium imaging, metabolomics, and disease modeling. Her collaborative approach is evident in numerous co-authorships across neuroscience, cardiology, and molecular biology disciplines, reflecting the interdisciplinary nature of her research program focused on bridging basic molecular mechanisms with potential clinical applications.

Anthony Rosenzweigمشاهده پروفایل

استاد

• Cardiovascular Research
• Heart Failure
• Exercise Physiology
• +۵ مورد دیگر

Dr. Anthony Rosenzweig, Professor of Internal Medicine - Cardiology at the University of Michigan Medical School, is a leading figure in cardiovascular research with a focus on heart failure, exercise physiology, and molecular cardiology. He previously held the Paul Dudley White Professorship of Medicine at Harvard Medical School (2015-2022) and served as Chief of Cardiology and Director of Cardiovascular Research at Massachusetts General Hospital. Harvard College (Biochemistry & Molecular Biology) Harvard Medical School (MD) Massachusetts General Hospital (Residency & Fellowship) University of Pennsylvania (Predoctoral Fellowship) Harvard Medical School (Postdoctoral Training) His research spans multiple groundbreaking areas including: Exercise-induced cardiac lymphatic remodeling for aging heart inflammation miRNA-based therapies for chemotherapy-induced cardiotoxicity Traditional Chinese Medicine applications in heart failure treatment (QLQX clinical trials) Stem cell-derived cardiomyocyte purification techniques Neural pathways linking stress to cardiovascular benefits Placental senescence mechanisms in peripartum cardiomyopathy Scientific contributions include leadership in the QUEST trial showing Qiliqiangxin's efficacy for HFrEF and pioneering work on exercise-regulated noncoding RNAs reversing vascular aging. He currently directs the Stanley and Judith Frankel Institute for Heart and Brain Health at University of Michigan. Paul Dudley White Professor of Medicine (2015-2022) Inaugural Director, Frankel Institute for Heart and Brain Health Leadership roles at MGH, Beth Israel Deaconess, and Harvard Stem Cell Institute Active in clinical translation, his work bridges molecular cardiology with regenerative medicine and metabolic research, while maintaining significant advisory roles in major cardiovascular organizations.

Sinem Karamanمشاهده پروفایل

دانشیار

• Vascular Biology
• Genetic Engineering
• Obesity
• +۶ مورد دیگر

Sinem Karaman is an Academy Research Fellow and Docent in Cell and Molecular Biology at the University of Helsinki's Faculty of Medicine. She serves as Principal Investigator of the Organotypic Vasculature Lab and supervises doctoral programs in Integrative Life Science and Biomedicine. Education: B.Sc. and M.Sc. in Molecular Biology from Istanbul Technical University (2006, 2008), Ph.D. from ETH Zurich (2012), Docent (2018). Her research focuses on organ-specific blood and lymphatic vasculature in development and disease, with expertise in obesity, diabetes, and inflammation . She applies intravital imaging and single-cell RNA sequencing to study vascular leakage and lymphatic dysfunction. Recent work includes multi-omics analyses of lymphedema-induced adipose tissue , Notch-WNT crosstalk in melanoma metastasis , and VEGFR3 signaling in dural lymphatics . She has published extensively in journals like Nature Cardiovascular Research and Cell Reports Medicine . Scientific Awards: Academy Research Fellow (2020) Early Career Researcher (2018) Research Grant (2018) Travel Award for Poster (2018) She leads projects funded by the Sigrid Jusélius Foundation , Finska Läkaresällskapet , and Åland Foundations , focusing on lymphatic regulation in metabolic diseases and adipose tissue dysfunction . Her lab supervises doctoral theses and collaborates internationally.

Lianping Xingمشاهده پروفایل

استاد

• Bone Biology
• Inflammatory Bone Diseases
• Osteoimmunology
• +۳ مورد دیگر

Lianping Xing is a Professor in the Department of Pathology and Laboratory Medicine at the University of Rochester School of Medicine and Dentistry. Her research focuses on inflammatory bone loss mechanisms using genetically modified animal models, in vivo imaging, and molecular approaches. NIH-funded research programs Expertise in osteoclast/osteoblast regulation Proposed novel arthritis therapeutics via lymphatic modulation Key contributions include: Elucidating TNF's role in joint tissue injury Discovering ubiquitin-mediated proteasomal degradation in mesenchymal stem cells Developing bone-targeted bortezomib conjugates Patent holder for inflammatory condition treatments Scientific Awards ASBMR Travel Award (2000) ORS Young Investigator Award (2000) ASBMR Most Outstanding Abstract (1997) ASBMR Young Investigator Award (1996)

Nick Willettمشاهده پروفایل

دانشیار

• Musculoskeletal Engineering
• Regenerative Medicine
• Biomechanics
• +۳ مورد دیگر

Nick Willett is an Associate Professor in the Department of Bioengineering at the University of Oregon’s Phil and Penny Knight Campus for Accelerating Scientific Impact. Previously, he served as an Associate Professor in the Department of Orthopaedics at Emory University. His research focuses on systems integration approaches for musculoskeletal disease and regenerative engineering, combining mechanical engineering principles with molecular biology techniques. Willett holds a PhD in Biomedical Engineering (2010) from a joint program between Georgia Tech and Emory University, and a B.S. in Mechanical Engineering (2005) from the University of Colorado at Boulder. His postdoctoral training was at Georgia Tech in Mechanical Engineering. His research interests include cell and biologic therapies for bone/muscle defects, multi-scale mechanical regulation of bone regeneration, and intra-articular therapeutic delivery for post-traumatic osteoarthritis. Key approaches involve biomaterial design, immune modulation, and rehabilitation strategies. Willett’s lab explores regenerative engineering solutions for complex extremity trauma, including novel imaging techniques and engineered therapies to address unmet clinical needs. Current projects emphasize musculoskeletal integration, lymphatic function optimization, and resolving chronic inflammation. His work bridges engineering and clinical disciplines, with applications in tissue regeneration, orthopedic trauma, and chronic injury recovery. Collaborations include academic and clinical institutions focusing on translational research.