Zhilei Shen

Dr. Zhilei Shen is Assistant Professor of Clinical Radiation Oncology at the University of Southern California, affiliated with USC Norris Cancer Hospital and USC + Los Angeles County Medical Center. She specializes in medical physics with expertise in Gamma Knife, SBRT, and brachytherapy.

Her research focuses on advanced treatment planning, deformable image registration, and image-guided radiation therapy. Key innovations include machine learning applications in instrument calibration and computational modeling for tumor targeting.

Publications demonstrate progressive refinement in radiation therapy techniques, particularly for complex brain and spinal cases. Recent work emphasizes spatially fractionated radiation, dosimetric validation, and patient-specific QA protocols.

Dr. Shen collaborates with multidisciplinary teams to develop portable monitoring devices and AI-driven calibration methods, enhancing precision in oncology practice.