معرفی
Zhigui Li is an Associate Research Scientist in the Department of Nephrology at Yale School of Medicine, Yale University. His work focuses on molecular mechanisms underlying kidney diseases, particularly podocyte biology, autophagy regulation, and oxidative stress responses. He holds a PhD from Nankai University and a BS from Guangxi University.
Research Interests: Dr. Li's research explores the interplay between miRNA regulation, autophagy pathways, and kidney dysfunction. Key areas include:
- Nephrology: Kidney disease pathogenesis and therapeutic targets
- Podocyte Differentiation: miRNA-driven developmental mechanisms
- Oxidative Stress: Role in cellular injury and neuroprotection
- Autophagy: Protective roles in diabetes, neurodegeneration, and toxicant exposure
Publications: His recent work addresses topics like Polycystin-1 dosage effects in kidney disease (2023 JASN), miR-200's role in podocyte maturation (2016 Scientific Reports), and autophagy's neuroprotective role in diabetes (2016 BBR). These studies highlight his multidisciplinary approach bridging nephrology, cell biology, and molecular medicine.
