معرفی
Dr. Zhaoyu Li is a Group Leader at the Queensland Brain Institute, The University of Queensland. His research focuses on understanding neural circuit function and behavior using the model organism Caenorhabditis elegans. Dr. Li employs advanced techniques including calcium imaging, optogenetics, and behavioral genetic screens to study how neural networks operate in healthy and diseased states, particularly in the context of neurodegenerative diseases. His work bridges molecular, cellular, and systems-level neuroscience to uncover fundamental principles of neural network dynamics.
Key research interests include neural circuit architecture, the impact of aging on locomotion behaviors, and the development of computational models to predict neural connectivity. Collaborative projects involve interdisciplinary approaches combining neuroscience with artificial intelligence for spatio-temporal behavior analysis.
Dr. Li's publications highlight contributions to understanding sensory processing (e.g., chemosensation, mechanosensation), neural network plasticity, and the molecular mechanisms underlying neurodegenerative conditions. His team's work has implications for translational research in Alzheimer's disease and other neurological disorders.
Current research emphasizes leveraging the fully mapped C. elegans connectome to dissect neural circuit dysfunction, with potential applications in therapeutic development. The Li Group actively develops novel tools for in vivo imaging and behavioral analysis to advance systems neuroscience.
