Zhanzhong Shi

Dr. Zhanzhong Shi is a Senior Lecturer in Biomedical Sciences at Middlesex University, affiliated with the Department of Natural Sciences. His research focuses on antimicrobial peptides and cancer biology, particularly exploring molecular signaling pathways and drug design strategies. He has contributed to studies on peptide structure-activity relationships, tumor cell proliferation mechanisms, and erythropoietin's role in oncogenesis.

Dr. Shi's work spans antimicrobial peptide optimization, including D-amino acid modifications and truncated analog design, as well as investigations into JAK/STAT signaling in cervical cancer and BRCA1 mutations in breast cancer. His studies often integrate molecular biology techniques with clinical applications, aiming to bridge basic research and therapeutic development.

Notable contributions include analyses of Erythropoietin (EPO) signaling in malignancies, revealing its role in promoting tumor cell survival and metastasis through multiple signaling pathways. His research also addresses challenges in antibody specificity and diagnostic biomarker validation in lung and blood cancers.

Dr. Shi has published extensively in peer-reviewed journals such as Antibiotics and Journal of Cellular Physiology, focusing on interdisciplinary approaches to understand disease mechanisms and develop novel treatment strategies. His work emphasizes translational research with potential clinical applications in oncology and infectious disease management.