Yuri Schwartz

Yuri Schwartz is an Associate Professor at the Department of Molecular Biology, Umeå University, Sweden. His research focuses on epigenetic regulation mediated by the Polycomb-Trithorax system, investigating how histone modifications and chromatin organization control gene expression in Drosophila melanogaster and human cell cultures.

Key research areas include:

• Epigenetic memory and transgenerational inheritance
• Polycomb/Trithorax-mediated chromatin folding
• Histone methylation and transcriptional repression
• Identification of non-histone substrates for Trithorax proteins

Recent publications highlight work on:

• 3D genome organization and chromatin dynamics
• CRISPR-Cas9 editing challenges in heterochromatin
• Evolutionary conservation of Polycomb complexes
• Role of H3K36 methylation in transposon control

His group employs genetic, biochemical, and computational approaches to address fundamental questions about epigenetic stability and its implications for personalized medicine and stem cell therapies.