معرفی
Professor Yun Wu is a faculty member in the Department of Biomedical Engineering at the School of Engineering and Applied Sciences, University at Buffalo. She leads the Engineered Theranostics Laboratory, focusing on nanotechnology-enabled solutions for cancer detection and treatment. Her research integrates engineering principles with biomedical applications.
- PhD in Chemical and Biomolecular Engineering from The Ohio State University (2009)
- Postdoctoral work at Ohio State's Nanoscale Science and Engineering Center (2009-2013)
- Assistant/Associate/Full Professor at University at Buffalo (2013-present)
Yun Wu's research spans cancer theranostics through:
- Development of multifunctional nanoparticles for drug/gene delivery
- Exosome-based biosensor platforms for liquid biopsy
- Microfluidic methods for nanoparticle synthesis
- Targeted cancer therapies overcoming drug resistance
- Biodegradable zwitterionic polymers as PEG alternatives
- Surface plasmon resonance biosensors for protein/RNA detection
Her 15 most recent publications demonstrate expertise in:
- Exosome isolation and biomarker analysis
- Lipoplex nanoparticle engineering
- Multi-drug delivery systems
- Photoacoustic and fluorescence imaging
- Pharmacokinetic modeling
- Clinical translation of nanotherapeutics
Current research grants include:
- $3.1M NCI grant for Exo-PROS lung cancer detection (2022-2027)
- $2.4M NIBIB project on zwitterionic polymer-drug conjugates (2023-2027)
- $0.4M NCI grant for exosomal glycoantigen biomarkers (2022-2024)
- Co-investigator in $0.9M NHLBI fibrosis-on-chip system (2020-2023)
Lab members include PhD, MS, and undergraduate researchers. Collaborations exist with Roswell Park Comprehensive Cancer Center and Mayo Clinic clinicians.
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