Yuji Nakada

Yuji Nakada is an Associate Professor specializing in cardiovascular regeneration and cell cycle regulation. His work focuses on understanding mechanisms of cardiomyocyte proliferation and myocardial regeneration across species, including mice, pigs, and humans. He employs advanced techniques such as single-nucleus RNA sequencing and artificial intelligence for data analysis. Key research themes include hypoxia-induced regeneration, drug discovery for heart repair, and engineered cardiac tissue models. Nakada's studies explore metabolic pathways, gene expression modulation, and surgical interventions to enhance cardiac function post-injury.

Recent projects involve identifying FDA-approved drugs that stimulate heart regeneration and developing three-dimensional cardiac spheroid cultures for better cell maturation. His laboratory also investigates the HIF-FOXM1 axis and YAP signaling pathways in promoting cardiomyocyte proliferation. Collaborative efforts integrate bioengineering approaches with biological insights to advance regenerative medicine strategies for cardiovascular diseases.