Yue Leng

Dr. Yue Leng is an Associate Professor in Psychiatry at the University of California, San Francisco (UCSF) Weill Institute for Neurosciences, with a research focus on sleep epidemiology and its relationship to neurodegenerative diseases. She holds a PhD in Epidemiology from the University of Cambridge and completed postdoctoral training in sleep and neurodegeneration at UCSF.

Research Interests

Her work bridges sleep science, neurodegeneration, and machine learning, investigating how

• napping patterns
• circadian disruptions
• sleep architecture
• digital sleep biomarkers

influence risk of Alzheimer's and Parkinson's disease. She develops behavioral sleep interventions for mild cognitive impairment patients.

Scientific Awards

• National Institute on Aging Pathway to Independence Award (K99/R00)
• Global Brain Health Institute Atlantic Fellow
• Cambridge International Scholarship
• China Medical Board Next Generation Fellowship

Research Funding

Principal Investigator for multiple NIH grants including

• R01AG083836 (2024-2029): Lifecourse sleep and Alzheimer's risk
• R21AG085495 (2023-2025): Polysomnography-based digital biomarkers
• R00AG056598 (2017-2024): Sleep and cognitive decline

Collaborations

Key collaborations with Kristine Yaffe, Katie Stone, and Sonia Ancoli-Israel across multiple institutions including UCSF and UCSD.