معرفی
Dr. Ysobel Baker is a Royal Society University Research Fellow at the School of Chemistry, University of Southampton. Her research focuses on DNA chemistry, Nucleic acid therapeutics, and Chemical biology, with a particular emphasis on designing novel nucleic acid modifications for biomedical applications.
- PhD in Chemistry (2015), University of Cambridge
- MChem (2011), University of Southampton (1st Class Honors)
Her work lies at the intersection of synthetic organic chemistry and biomedical sciences, developing antisense oligonucleotides (ASOs) for disease targeting RNA and creating bioconjugation tools to improve therapeutic delivery. She also develops chemically modified DNA for studying biological systems and advancing diagnostic technologies.
Recent publications highlight her team's breakthroughs in triazole-linked DNA modifications, amide linkages for stability, and metal-DNA nanoflowers with applications in drug delivery and bioimaging. These works reflect her expertise in organic synthesis, nucleic acid engineering, and nanomaterials.
She actively supervises PhD students in the ChemLife Network and collaborates with the Institute for Life Sciences, Chemical Biology, and Organic and Biological Chemistry groups. Her research is funded by the Royal Society and Wessex Medical Research.
