Yosta de Stigter

Yosta de Stigter is a doctoral candidate at the Department of Biomedical Engineering, Eindhoven University of Technology, with a focus on protein engineering and bioluminescence-based diagnostic tools. She has published two peer-reviewed articles and is actively contributing to interdisciplinary research.

Research interests include

• Engineering luciferase-intercalating dye conjugates for nucleic acid detection
• Artificial intelligence in protein design
• Bioluminescence and its applications in diagnostics
• Isothermal nucleic acid detection methods

Recent publications highlight trends in integrating computational approaches with biochemical innovation

• 2025 commentary in Chem on AI-driven luciferase design
• 2024 article in ACS Chemical Biology on bioluminescent dyes for ratiometric DNA/RNA detection

Yosta's work has accumulated 4 citations and is available in open access. She collaborates with researchers such as M. Merkx, H. J. van der Veer, and B. J. H. M. Rosier. Contact her at y.d.stigter@tue.nl.